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The map label for this gene is mrp [C]

Identifier: 220904461

GI number: 220904461

Start: 1403748

End: 1404662

Strand: Direct

Name: mrp [C]

Synonym: Ddes_1191

Alternate gene names: 220904461

Gene position: 1403748-1404662 (Clockwise)

Preceding gene: 220904460

Following gene: 220904462

Centisome position: 48.85

GC content: 55.85

Gene sequence:

>915_bases
ATGGCTTCCTGTTCCTCCTGTTCTTCATCTTCCTCCTGTCCAAGCGCCACGGGCAAGGGTGGAGACGGAAAATGCAGTGA
CCCTGTCGCCCGGCAGGACAAAATCATCGCCGACAGGCTCGGGCATATACGGCACAAGCTTTTCGTCATGAGCGGCAAGG
GCGGGGTGGGTAAAAGTTCCGTCACCGTCAATACTGCCGCAGCCCTGGCCCGGCGTGGTTTCAAGGTGGGCATTCTCGAT
GTGGACCTGCACGGCCCCAGTGTGCCCAACCTGCTGGGCCTCAAAAGCACCGTCGAGATGGACCCCGGCGGCGAGCTTAT
GCTGCCAGCGACCTATAATGAAAATTTGTCTGTCATTTCTATGGACTCACTGCTGCAGGACAAGGATCAGGCCATCCTGT
GGCGTGGTCCGAAAAAAACGGCTGCTATCAGGCAGTTTATTTCGGATGTGAAGTGGGGCGATCTTGATTTTCTGCTTATT
GACTCGCCTCCAGGCACTGGTGATGAGCATATGACGGTCATGCAGTCCATCCCTGACGCGCTTTGTGTGGTCGTGACCAC
ACCGCAGGAAATTTCCCTGGCGGATGTGCGCAAGGCCATCAATTTTCTCCAGTATACCAACTCCAATGTTCTTGGCGTAG
TAGAAAATATGAGCGGTCTTGTGTGCCCGCACTGTCATCAGGAAATTGATCTTTTCAAGAAAGGCGGCGGCGAAGATCTC
GCAAAACGCTACGGCCTCAAGTTCCTGGGGGCCGTGCCTTTGGATCCCACCACTGTGGTTGCTGCGGACCGCGGGGTTCC
TGTGGTGTATCTTGAATCGGAAAGCCCAGCCAAAGCTGCCTTTCTTCAATTGGCAGACGCCATTGCCGATGCCTGCGACA
ACAGCCTGGAGGCTTTGGCCACCTCGCGCTCCTAG

Upstream 100 bases:

>100_bases
CGCATGACCGGGGAAGACCTCGGTCCCGCTATTTTTGTGGACCTGGTGGGCGACCACGGCTGGTAGCACGGCCTCTCGCC
ATCAAAAACAAGGAGATGTC

Downstream 100 bases:

>100_bases
GAATGCCCCTGGCCCCGGCTGACACTGATTCGCCGCAGTGCACAAGGCTGTTTTTCAGTAATTTGTGCAAGAAGGTAAAA
GCCGGAAAAGCGGGTGGAGT

Product: Mrp protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MASCSSCSSSSSCPSATGKGGDGKCSDPVARQDKIIADRLGHIRHKLFVMSGKGGVGKSSVTVNTAAALARRGFKVGILD
VDLHGPSVPNLLGLKSTVEMDPGGELMLPATYNENLSVISMDSLLQDKDQAILWRGPKKTAAIRQFISDVKWGDLDFLLI
DSPPGTGDEHMTVMQSIPDALCVVVTTPQEISLADVRKAINFLQYTNSNVLGVVENMSGLVCPHCHQEIDLFKKGGGEDL
AKRYGLKFLGAVPLDPTTVVAADRGVPVVYLESESPAKAAFLQLADAIADACDNSLEALATSRS

Sequences:

>Translated_304_residues
MASCSSCSSSSSCPSATGKGGDGKCSDPVARQDKIIADRLGHIRHKLFVMSGKGGVGKSSVTVNTAAALARRGFKVGILD
VDLHGPSVPNLLGLKSTVEMDPGGELMLPATYNENLSVISMDSLLQDKDQAILWRGPKKTAAIRQFISDVKWGDLDFLLI
DSPPGTGDEHMTVMQSIPDALCVVVTTPQEISLADVRKAINFLQYTNSNVLGVVENMSGLVCPHCHQEIDLFKKGGGEDL
AKRYGLKFLGAVPLDPTTVVAADRGVPVVYLESESPAKAAFLQLADAIADACDNSLEALATSRS
>Mature_303_residues
ASCSSCSSSSSCPSATGKGGDGKCSDPVARQDKIIADRLGHIRHKLFVMSGKGGVGKSSVTVNTAAALARRGFKVGILDV
DLHGPSVPNLLGLKSTVEMDPGGELMLPATYNENLSVISMDSLLQDKDQAILWRGPKKTAAIRQFISDVKWGDLDFLLID
SPPGTGDEHMTVMQSIPDALCVVVTTPQEISLADVRKAINFLQYTNSNVLGVVENMSGLVCPHCHQEIDLFKKGGGEDLA
KRYGLKFLGAVPLDPTTVVAADRGVPVVYLESESPAKAAFLQLADAIADACDNSLEALATSRS

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=257, Percent_Identity=45.5252918287938, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI118572611, Length=298, Percent_Identity=38.255033557047, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI157384956, Length=245, Percent_Identity=39.5918367346939, Blast_Score=173, Evalue=2e-43,
Organism=Escherichia coli, GI87082045, Length=247, Percent_Identity=43.7246963562753, Blast_Score=195, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI25143050, Length=294, Percent_Identity=41.4965986394558, Blast_Score=214, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6322188, Length=250, Percent_Identity=46.8, Blast_Score=235, Evalue=7e-63,
Organism=Saccharomyces cerevisiae, GI6321347, Length=296, Percent_Identity=42.5675675675676, Blast_Score=223, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24667611, Length=224, Percent_Identity=48.6607142857143, Blast_Score=223, Evalue=9e-59,
Organism=Drosophila melanogaster, GI19921440, Length=273, Percent_Identity=42.1245421245421, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI221511043, Length=247, Percent_Identity=36.0323886639676, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 32114; Mature: 31983

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASCSSCSSSSSCPSATGKGGDGKCSDPVARQDKIIADRLGHIRHKLFVMSGKGGVGKSS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCC
VTVNTAAALARRGFKVGILDVDLHGPSVPNLLGLKSTVEMDPGGELMLPATYNENLSVIS
EEEHHHHHHHHCCCEEEEEEEECCCCCCCCHHCCCEEEEECCCCCEEEEEECCCCEEEEE
MDSLLQDKDQAILWRGPKKTAAIRQFISDVKWGDLDFLLIDSPPGTGDEHMTVMQSIPDA
HHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCE
LCVVVTTPQEISLADVRKAINFLQYTNSNVLGVVENMSGLVCPHCHQEIDLFKKGGGEDL
EEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHH
AKRYGLKFLGAVPLDPTTVVAADRGVPVVYLESESPAKAAFLQLADAIADACDNSLEALA
HHHCCCCEEECCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHH
TSRS
CCCC
>Mature Secondary Structure 
ASCSSCSSSSSCPSATGKGGDGKCSDPVARQDKIIADRLGHIRHKLFVMSGKGGVGKSS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCC
VTVNTAAALARRGFKVGILDVDLHGPSVPNLLGLKSTVEMDPGGELMLPATYNENLSVIS
EEEHHHHHHHHCCCEEEEEEEECCCCCCCCHHCCCEEEEECCCCCEEEEEECCCCEEEEE
MDSLLQDKDQAILWRGPKKTAAIRQFISDVKWGDLDFLLIDSPPGTGDEHMTVMQSIPDA
HHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCE
LCVVVTTPQEISLADVRKAINFLQYTNSNVLGVVENMSGLVCPHCHQEIDLFKKGGGEDL
EEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHH
AKRYGLKFLGAVPLDPTTVVAADRGVPVVYLESESPAKAAFLQLADAIADACDNSLEALA
HHHCCCCEEECCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHH
TSRS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]