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The map label for this gene is pgsA [H]

Identifier: 220904462

GI number: 220904462

Start: 1404891

End: 1405451

Strand: Direct

Name: pgsA [H]

Synonym: Ddes_1192

Alternate gene names: 220904462

Gene position: 1404891-1405451 (Clockwise)

Preceding gene: 220904461

Following gene: 220904463

Centisome position: 48.89

GC content: 53.65

Gene sequence:

>561_bases
ATGCTTAACCTTGCTAATAAAATTACGCTGTTACGTATTCTTATGACCCCTCTGGTGGTTTTACTGCTTTACTTTGAAGG
TCCGACGGTGTGCAAGATCGCGGCCTTGGCCTTTATTTTTGCCTCAGTGACTGACTGGGCTGACGGTTATGTGGCCCGGC
GTTCCAACATGGTTACCAGCATGGGCAAGTTTCTGGACCCGCTGGCCGACAAGGTGCTCATCTGCTCTGTGCTCATCATG
TTTGTTCAGCTCGGCTGGACTGAGGCCTGGGTCGTTATCATCATGGTTTGTCGTGAACTTGTAGTCACAGGCCTTCGCGC
CATTGCCATTGACGAAGGCATTGTGCTTGCTGCGGACAAGTTCGGCAAGGCCAAGACGATTCTGCAGGTTTTTGCCATTG
TTCCCCTGACCCTGCATTATCCCCTGTGGGGTATGGACCCGCAGCCCATAGGGCAGCTCCTGTTGTATGCCGCGCTGGCG
CTGGCGCTTATTTCCGGCACCAACTACTGCTATGATTTCTACCGTCGTACCCGCGAGCGCAAGGATTCCGGCAAGGCATG
A

Upstream 100 bases:

>100_bases
CGGATTGCGCAAACCCGGCAGGGAGATTTTTTCTTCTTTTCTCTCGTCTGCTTTTATGTTACTTGGACAAAAATTCTCCG
GGAGAGTCAAAATAAATACA

Downstream 100 bases:

>100_bases
GCACGCTGCAGATACGCCTCAAAAACTGTATCCAGACCATACTGGAGCTGGAGCCGGATATGAAAGCCGGAATGTGGGGG
CGCTATTTCGATTCAGAATT

Product: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MLNLANKITLLRILMTPLVVLLLYFEGPTVCKIAALAFIFASVTDWADGYVARRSNMVTSMGKFLDPLADKVLICSVLIM
FVQLGWTEAWVVIIMVCRELVVTGLRAIAIDEGIVLAADKFGKAKTILQVFAIVPLTLHYPLWGMDPQPIGQLLLYAALA
LALISGTNYCYDFYRRTRERKDSGKA

Sequences:

>Translated_186_residues
MLNLANKITLLRILMTPLVVLLLYFEGPTVCKIAALAFIFASVTDWADGYVARRSNMVTSMGKFLDPLADKVLICSVLIM
FVQLGWTEAWVVIIMVCRELVVTGLRAIAIDEGIVLAADKFGKAKTILQVFAIVPLTLHYPLWGMDPQPIGQLLLYAALA
LALISGTNYCYDFYRRTRERKDSGKA
>Mature_186_residues
MLNLANKITLLRILMTPLVVLLLYFEGPTVCKIAALAFIFASVTDWADGYVARRSNMVTSMGKFLDPLADKVLICSVLIM
FVQLGWTEAWVVIIMVCRELVVTGLRAIAIDEGIVLAADKFGKAKTILQVFAIVPLTLHYPLWGMDPQPIGQLLLYAALA
LALISGTNYCYDFYRRTRERKDSGKA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=173, Percent_Identity=33.5260115606936, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20675; Mature: 20675

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLANKITLLRILMTPLVVLLLYFEGPTVCKIAALAFIFASVTDWADGYVARRSNMVTS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGKFLDPLADKVLICSVLIMFVQLGWTEAWVVIIMVCRELVVTGLRAIAIDEGIVLAADK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
FGKAKTILQVFAIVPLTLHYPLWGMDPQPIGQLLLYAALALALISGTNYCYDFYRRTRER
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KDSGKA
HCCCCC
>Mature Secondary Structure
MLNLANKITLLRILMTPLVVLLLYFEGPTVCKIAALAFIFASVTDWADGYVARRSNMVTS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGKFLDPLADKVLICSVLIMFVQLGWTEAWVVIIMVCRELVVTGLRAIAIDEGIVLAADK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
FGKAKTILQVFAIVPLTLHYPLWGMDPQPIGQLLLYAALALALISGTNYCYDFYRRTRER
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KDSGKA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA