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The map label for this gene is xerD [H]

Identifier: 220904455

GI number: 220904455

Start: 1394435

End: 1395367

Strand: Reverse

Name: xerD [H]

Synonym: Ddes_1185

Alternate gene names: 220904455

Gene position: 1395367-1394435 (Counterclockwise)

Preceding gene: 220904458

Following gene: 220904454

Centisome position: 48.56

GC content: 55.84

Gene sequence:

>933_bases
ATGATCAAACAAGACACGGCCCCATCATTCCTCTGTCCGCTGGCCCCTCTGTTGCCGCTATGGCAGGATTATCTGCTGGC
CCAACGGGGGCTGTCGCCCCAGACCGTTGCCTCTTACGGGCAAGACCTTGAAAATTTTTTCCTTTTTCGTCAGGAACTGG
CCCAGGGCGAAGCAGTAAGCCCCCAACCAGATGAACAGGAAATTTTCCTCTATCTGGCATGGTTGCGCGCCCGGCAGAAC
ACAGGACGGACATTGGCGCGCCGCCTTTCAGCATTGCGGGCTTTTTTTGATTTTGCCGTACAGGAAAACGCCATAAAAAA
TAATCCTGCGCAATTGCTGGACAATCCAAAACTGCCCCAACACCTGCCCGAAGTACTGAGCCGGGATGAAATGGAATCCC
TGCTGGCACGGCCCGATCTGCGTGACAGGGGCGGCCAGCGCGACCGCTGCATACTCGAACTGCTCTATGCCGCTGGCCTG
CGGGTGTCTGAACTGTGCGATCTGTGTTTGCCCGATCTGGACCTTCAGCGCGGATTGGTACGTGTTTTCGGCAAGGGAGC
CAAAGAACGCCTTGTGCCGCTGCATGATCTTATGCAGAACATGCTTGAAAATTACATCCGTGATTGGCGCCCGGCTTTTT
CACCCACAGGCAACCAGCTTTTCGTCAATCGTTCCGGCCGTGCGCTGACACGGCAGTATATCTGGAAGATGGTAAAAAAA
TACGCTCTGGAGGCAGGCATACGCCGCCCGGTTTCTCCCCATACATTCCGTCATTCTTTTGCCACACACCTGCTTGAAGG
CGGCGCGGACCTGCGGGCGGTGCAATTGCTGCTCGGTCATGCCGACATCAGCGCCACAGAAATATATACCCATGTACAGG
CAGAGCGCCTGCGTAGCATCCACCGCAAATTCCACCCCCGGAGCCAGATGTGA

Upstream 100 bases:

>100_bases
CAAAAGGAACAAAAGCCTCTGCACAAACCTTTTGTACCGCATCCGGTTGGGAACATGTAAAAAACTTGCCCGTCCGGCAC
AAGGCGGCTAGCATACGCGT

Downstream 100 bases:

>100_bases
GCCATGTGAGTGCTGCCAAAGCCACGCTGATAACCTGCCATGCCAATGCGGACTTTGACGCCTTCGCCGCCATGCTGGCC
GCCCGCCACCTGTACAGCCC

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MIKQDTAPSFLCPLAPLLPLWQDYLLAQRGLSPQTVASYGQDLENFFLFRQELAQGEAVSPQPDEQEIFLYLAWLRARQN
TGRTLARRLSALRAFFDFAVQENAIKNNPAQLLDNPKLPQHLPEVLSRDEMESLLARPDLRDRGGQRDRCILELLYAAGL
RVSELCDLCLPDLDLQRGLVRVFGKGAKERLVPLHDLMQNMLENYIRDWRPAFSPTGNQLFVNRSGRALTRQYIWKMVKK
YALEAGIRRPVSPHTFRHSFATHLLEGGADLRAVQLLLGHADISATEIYTHVQAERLRSIHRKFHPRSQM

Sequences:

>Translated_310_residues
MIKQDTAPSFLCPLAPLLPLWQDYLLAQRGLSPQTVASYGQDLENFFLFRQELAQGEAVSPQPDEQEIFLYLAWLRARQN
TGRTLARRLSALRAFFDFAVQENAIKNNPAQLLDNPKLPQHLPEVLSRDEMESLLARPDLRDRGGQRDRCILELLYAAGL
RVSELCDLCLPDLDLQRGLVRVFGKGAKERLVPLHDLMQNMLENYIRDWRPAFSPTGNQLFVNRSGRALTRQYIWKMVKK
YALEAGIRRPVSPHTFRHSFATHLLEGGADLRAVQLLLGHADISATEIYTHVQAERLRSIHRKFHPRSQM
>Mature_310_residues
MIKQDTAPSFLCPLAPLLPLWQDYLLAQRGLSPQTVASYGQDLENFFLFRQELAQGEAVSPQPDEQEIFLYLAWLRARQN
TGRTLARRLSALRAFFDFAVQENAIKNNPAQLLDNPKLPQHLPEVLSRDEMESLLARPDLRDRGGQRDRCILELLYAAGL
RVSELCDLCLPDLDLQRGLVRVFGKGAKERLVPLHDLMQNMLENYIRDWRPAFSPTGNQLFVNRSGRALTRQYIWKMVKK
YALEAGIRRPVSPHTFRHSFATHLLEGGADLRAVQLLLGHADISATEIYTHVQAERLRSIHRKFHPRSQM

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=42.1232876712329, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1790244, Length=286, Percent_Identity=39.8601398601399, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1790768, Length=157, Percent_Identity=33.7579617834395, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790767, Length=179, Percent_Identity=28.4916201117318, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35572; Mature: 35572

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQDTAPSFLCPLAPLLPLWQDYLLAQRGLSPQTVASYGQDLENFFLFRQELAQGEAVS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQPDEQEIFLYLAWLRARQNTGRTLARRLSALRAFFDFAVQENAIKNNPAQLLDNPKLPQ
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHH
HLPEVLSRDEMESLLARPDLRDRGGQRDRCILELLYAAGLRVSELCDLCLPDLDLQRGLV
HHHHHHCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH
RVFGKGAKERLVPLHDLMQNMLENYIRDWRPAFSPTGNQLFVNRSGRALTRQYIWKMVKK
HHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
YALEAGIRRPVSPHTFRHSFATHLLEGGADLRAVQLLLGHADISATEIYTHVQAERLRSI
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HRKFHPRSQM
HHHCCCCCCC
>Mature Secondary Structure
MIKQDTAPSFLCPLAPLLPLWQDYLLAQRGLSPQTVASYGQDLENFFLFRQELAQGEAVS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQPDEQEIFLYLAWLRARQNTGRTLARRLSALRAFFDFAVQENAIKNNPAQLLDNPKLPQ
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHH
HLPEVLSRDEMESLLARPDLRDRGGQRDRCILELLYAAGLRVSELCDLCLPDLDLQRGLV
HHHHHHCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH
RVFGKGAKERLVPLHDLMQNMLENYIRDWRPAFSPTGNQLFVNRSGRALTRQYIWKMVKK
HHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
YALEAGIRRPVSPHTFRHSFATHLLEGGADLRAVQLLLGHADISATEIYTHVQAERLRSI
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HRKFHPRSQM
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA