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The map label for this gene is udg [H]

Identifier: 220904415

GI number: 220904415

Start: 1346906

End: 1348240

Strand: Direct

Name: udg [H]

Synonym: Ddes_1145

Alternate gene names: 220904415

Gene position: 1346906-1348240 (Clockwise)

Preceding gene: 220904409

Following gene: 220904416

Centisome position: 46.87

GC content: 55.36

Gene sequence:

>1335_bases
ATGAAATTGTGCATTATCGGCACCGGCTATGTTGGTCTGGTCAGCGCCGCCTGCTTTGCGGAAATGGGCAATACCGTAAC
GTGCGTTGATGTGAATCCCGAAGTGGTAAAAAAGCTGAATGCGGGATCTGTGCATATATTTGAACCCGGCCTTGAGCCGA
TGGTGCGCCACAGTCGCGCAGACGGGCGGCTGACCTTCACTACCAGGCTTGAAGAAGGCATTGCCCAGGCTGATTGTGCT
TTTATTTGTGTAGGCACGCCGCCGCAACCTGACGGCTCGTGCGACTTGAGCTTTGTCCGGCAGGTTGCCAGAGAAATCGG
CCAGTACATGCAGAAAGACATGGTAGTTGTGGATAAGTCCACTGTACCTGTGGGAACTGCGGACGAAGTGCGCGGCCTCA
TTGACAAGGAATTGAAAAAACGTGGCGTGGATTTGCGTGTGGATGTGGTTTCCAATCCAGAGTTTCTTAAAGAAGGCGAT
GCCATTGCCGACTTTATGAAGCCTGACCGCGTGGTCATCGGTACGGATTCGGAGAAGGCCGCTACCCTTATGCGTGAGCT
TTACTCACCGTTTGCCCGCACCCGGGATAAAATCATTGTTATGGGCGTGCGCAGTGCGGAAATGACCAAGTACGCGGCCA
ACTGCATGCTTGCCACGAAAATTTCATTTATCAATGAAATTGCCACCATCTGCGAACAGGTGGGCGCGGATGTGCGTGAT
GTGCGCACGGGCATCGGCTCGGATTCCCGTATCGGCTATCAGTTCATCTACCCCGGCGTGGGGTACGGCGGCTCGTGCTT
TCCCAAGGACGTAAAGGCGCTTATCCGCACTGCGGAAAACGCGGGGGTCGAGCCGAGGCTGCTCAACGCGGTTGAGGCCG
TCAATGCCAGACAGAAAAAATATATGGCTGCCCGGGTGGAAGAATACTTTGCGCCGCAGGGAGGCGTGGCAGGCAAAACC
CTGACCATGTGGGGACTGGCCTTCAAGGCCAACACCGATGATATGCGTGAAGCCGCCGCCATTACCATTATCAATGAGCT
GACGGCCAAGGGCATGAAAATTCGTGCATTTGACCCCGTTGCCGCTGACAATGCCCGTAGTATCTTTGCGGATAACAAGC
TGGTAGAGATCGTGGATGACCAGTACGCGGCCTGTCAGGGCGCACAGGGCCTTATGGTTGTGACGGAATGGAACCAGTTC
CGCAATCCCGACTTTGAAAAAGTACGCGGGCTGCTGACGGCGCCTCTGCTGTTCGATGGGCGTAACCTGTACTCTCCTTC
CGCCATGGCCGAGCGCGGCTTTGCCTATTTTTGCATCGGCCGGGCAAGCGTTTAG

Upstream 100 bases:

>100_bases
AAAAATGTCGTATATGCGGCCATTCGGAAAACTATTTTGACCCGTTCCTGGCTGTAACGTCAAGGGCGCAGCCAGGTCAG
GACGCAGGAGAACGTCATAT

Downstream 100 bases:

>100_bases
CTTATAAGCTGCGCCGGATTGCAATGGCCTTGCAGTACGCCAAGGGGGGTGAACGAATCACGTTCACCCCCCTTTTTGTA
TATGTAAAGATGGTCGCCGT

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKLCIIGTGYVGLVSAACFAEMGNTVTCVDVNPEVVKKLNAGSVHIFEPGLEPMVRHSRADGRLTFTTRLEEGIAQADCA
FICVGTPPQPDGSCDLSFVRQVAREIGQYMQKDMVVVDKSTVPVGTADEVRGLIDKELKKRGVDLRVDVVSNPEFLKEGD
AIADFMKPDRVVIGTDSEKAATLMRELYSPFARTRDKIIVMGVRSAEMTKYAANCMLATKISFINEIATICEQVGADVRD
VRTGIGSDSRIGYQFIYPGVGYGGSCFPKDVKALIRTAENAGVEPRLLNAVEAVNARQKKYMAARVEEYFAPQGGVAGKT
LTMWGLAFKANTDDMREAAAITIINELTAKGMKIRAFDPVAADNARSIFADNKLVEIVDDQYAACQGAQGLMVVTEWNQF
RNPDFEKVRGLLTAPLLFDGRNLYSPSAMAERGFAYFCIGRASV

Sequences:

>Translated_444_residues
MKLCIIGTGYVGLVSAACFAEMGNTVTCVDVNPEVVKKLNAGSVHIFEPGLEPMVRHSRADGRLTFTTRLEEGIAQADCA
FICVGTPPQPDGSCDLSFVRQVAREIGQYMQKDMVVVDKSTVPVGTADEVRGLIDKELKKRGVDLRVDVVSNPEFLKEGD
AIADFMKPDRVVIGTDSEKAATLMRELYSPFARTRDKIIVMGVRSAEMTKYAANCMLATKISFINEIATICEQVGADVRD
VRTGIGSDSRIGYQFIYPGVGYGGSCFPKDVKALIRTAENAGVEPRLLNAVEAVNARQKKYMAARVEEYFAPQGGVAGKT
LTMWGLAFKANTDDMREAAAITIINELTAKGMKIRAFDPVAADNARSIFADNKLVEIVDDQYAACQGAQGLMVVTEWNQF
RNPDFEKVRGLLTAPLLFDGRNLYSPSAMAERGFAYFCIGRASV
>Mature_444_residues
MKLCIIGTGYVGLVSAACFAEMGNTVTCVDVNPEVVKKLNAGSVHIFEPGLEPMVRHSRADGRLTFTTRLEEGIAQADCA
FICVGTPPQPDGSCDLSFVRQVAREIGQYMQKDMVVVDKSTVPVGTADEVRGLIDKELKKRGVDLRVDVVSNPEFLKEGD
AIADFMKPDRVVIGTDSEKAATLMRELYSPFARTRDKIIVMGVRSAEMTKYAANCMLATKISFINEIATICEQVGADVRD
VRTGIGSDSRIGYQFIYPGVGYGGSCFPKDVKALIRTAENAGVEPRLLNAVEAVNARQKKYMAARVEEYFAPQGGVAGKT
LTMWGLAFKANTDDMREAAAITIINELTAKGMKIRAFDPVAADNARSIFADNKLVEIVDDQYAACQGAQGLMVVTEWNQF
RNPDFEKVRGLLTAPLLFDGRNLYSPSAMAERGFAYFCIGRASV

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=466, Percent_Identity=35.6223175965665, Blast_Score=261, Evalue=7e-70,
Organism=Homo sapiens, GI296040438, Length=368, Percent_Identity=35.3260869565217, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI296040443, Length=314, Percent_Identity=35.6687898089172, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1788340, Length=368, Percent_Identity=27.7173913043478, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI48994968, Length=360, Percent_Identity=30.2777777777778, Blast_Score=136, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17560350, Length=467, Percent_Identity=35.9743040685225, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI17136908, Length=467, Percent_Identity=34.475374732334, Blast_Score=253, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48388; Mature: 48388

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLCIIGTGYVGLVSAACFAEMGNTVTCVDVNPEVVKKLNAGSVHIFEPGLEPMVRHSRA
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCEEEEECCCCHHHHHHCCC
DGRLTFTTRLEEGIAQADCAFICVGTPPQPDGSCDLSFVRQVAREIGQYMQKDMVVVDKS
CCEEEEEEEHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEECC
TVPVGTADEVRGLIDKELKKRGVDLRVDVVSNPEFLKEGDAIADFMKPDRVVIGTDSEKA
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCHHHHHCCCCEEEEECCCHHH
ATLMRELYSPFARTRDKIIVMGVRSAEMTKYAANCMLATKISFINEIATICEQVGADVRD
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRTGIGSDSRIGYQFIYPGVGYGGSCFPKDVKALIRTAENAGVEPRLLNAVEAVNARQKK
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YMAARVEEYFAPQGGVAGKTLTMWGLAFKANTDDMREAAAITIINELTAKGMKIRAFDPV
HHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEECCC
AADNARSIFADNKLVEIVDDQYAACQGAQGLMVVTEWNQFRNPDFEKVRGLLTAPLLFDG
CCCCCCEECCCCCEEEECCCHHHHHCCCCCEEEEEECHHCCCCCHHHHHHHHHCCEEECC
RNLYSPSAMAERGFAYFCIGRASV
CCCCCCHHHHHCCCEEEEEECCCC
>Mature Secondary Structure
MKLCIIGTGYVGLVSAACFAEMGNTVTCVDVNPEVVKKLNAGSVHIFEPGLEPMVRHSRA
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCEEEEECCCCHHHHHHCCC
DGRLTFTTRLEEGIAQADCAFICVGTPPQPDGSCDLSFVRQVAREIGQYMQKDMVVVDKS
CCEEEEEEEHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEECC
TVPVGTADEVRGLIDKELKKRGVDLRVDVVSNPEFLKEGDAIADFMKPDRVVIGTDSEKA
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCHHHHHCCCCEEEEECCCHHH
ATLMRELYSPFARTRDKIIVMGVRSAEMTKYAANCMLATKISFINEIATICEQVGADVRD
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRTGIGSDSRIGYQFIYPGVGYGGSCFPKDVKALIRTAENAGVEPRLLNAVEAVNARQKK
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YMAARVEEYFAPQGGVAGKTLTMWGLAFKANTDDMREAAAITIINELTAKGMKIRAFDPV
HHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEECCC
AADNARSIFADNKLVEIVDDQYAACQGAQGLMVVTEWNQFRNPDFEKVRGLLTAPLLFDG
CCCCCCEECCCCCEEEECCCHHHHHCCCCCEEEEEECHHCCCCCHHHHHHHHHCCEEECC
RNLYSPSAMAERGFAYFCIGRASV
CCCCCCHHHHHCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]