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The map label for this gene is argD [H]

Identifier: 218905269

GI number: 218905269

Start: 3964835

End: 3965995

Strand: Reverse

Name: argD [H]

Synonym: BCAH820_4153

Alternate gene names: 218905269

Gene position: 3965995-3964835 (Counterclockwise)

Preceding gene: 218905270

Following gene: 218905268

Centisome position: 74.79

GC content: 38.85

Gene sequence:

>1161_bases
ATGATAAGTCATCTTTTTCAAACGTATGGGAGAAGAACTGTTGAGTTTGTAAAGGGGAATGGAACGAAAGTCATTGATAA
CAACGGTAAACAATATTTAGATTTCACATCAGGGATTGGTGTATGTAATTTAGGGCATTGCCATCCTACTGTTATGAAAG
CGGTACAAGAGCAACTTAATGATATATGGCATATATCTAATTTGTTTACAAATAGCTTACAAGAAGAAGTCGCGTCATTA
TTAACAGAAAATATAGCATTAGATTATGTGTTCTTCTGTAATAGCGGGGCAGAGGCGAATGAAGCAGCTTTGAAGCTAGC
CCGTAAGCATACTGGAAAATCTCTCGTCGTAACGTGTGAGCAGTCTTTTCACGGTAGAACATTCGGAACGATGAGTGCGA
CGGGACAAAATAAAGTGAAAGAAGGGTTTGGTCCGCTCCTTCCGTCTTTTTTACATACTCCATTTAACGATATAAAGGCG
CTCAAGGAAGTAATGAATGAAGAAGTTGCGGCAGTAATGGTAGAAGTTGTTCAAGGAGAGGGAGGAGTCATACCTGCTGA
TCTATCCTTTTTGAAAGAGATTGAAACATTATGTAAGAAGTTTGGTTCCTTATTTATTATAGACGAAGTACAAACAGGGA
TCGGAAGAACAGGTACATTATTTGCTTACGAACAAATGGGAATAGATCCTCATATCGTTACTACCGCTAAGGCGCTTGGA
AATGGGATTCCTGTCGGAGCAATGATTGGCCGGAAAGAACTCGGAACGTCGTTCACTGCAGGATCGCACGGTTCAACGTT
TGGCGGAAATTATGTTGCAATGGCTGCAGCGGAAGCAGTATTGCAAGTAAGTAAAAGACCATCGTTTTTAAAAGAAGTAC
AAGAAAAGGGCGAGTACGTATTACAGAAGTTGCAAGAGGAATTACAACATGTCGAATGTATTCAAAATATACGTGGAAAG
GGGCTTATGATTGGGATTGAGTGTAAGCATGAAGTTGCAAGTTTTATAGAACAACTAGAGAAAGAAGGGCTTCTCGTATT
ACAAGCAGGACCTAATGTGATAAGACTATTACCACCACTTATTGTGACGAATGAAGAGTTAGAACAGGCAGTATATATGA
TAAAAAAAGTAGTTTGTACAAAAAACGTATCAATTATATAA

Upstream 100 bases:

>100_bases
TGGGAGTGCAAAAGATAAGTATCGTAAATGGTACAAAAGATTTTACTGAAGATACAGGAGAATGTATTGGAACGACGGTA
ACGAGGGGAGTGAGTATCGT

Downstream 100 bases:

>100_bases
GGGGGAAATTTCATGTCAACTGTACAAGTACCGAAATTAAATACGAAAGATCTTTTAACATTAGAAGAACTGACGCAAGA
AGAAATCATTTCTTTAATTG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYVLQKLQEELQHVECIQNIRGK
GLMIGIECKHEVASFIEQLEKEGLLVLQAGPNVIRLLPPLIVTNEELEQAVYMIKKVVCTKNVSII

Sequences:

>Translated_386_residues
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYVLQKLQEELQHVECIQNIRGK
GLMIGIECKHEVASFIEQLEKEGLLVLQAGPNVIRLLPPLIVTNEELEQAVYMIKKVVCTKNVSII
>Mature_386_residues
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYVLQKLQEELQHVECIQNIRGK
GLMIGIECKHEVASFIEQLEKEGLLVLQAGPNVIRLLPPLIVTNEELEQAVYMIKKVVCTKNVSII

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=388, Percent_Identity=32.2164948453608, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=31.1059907834101, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=33.5548172757475, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI37574042, Length=413, Percent_Identity=27.8450363196126, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=27.9411764705882, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI226442709, Length=378, Percent_Identity=28.042328042328, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI226442705, Length=413, Percent_Identity=26.8765133171913, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI188536080, Length=415, Percent_Identity=22.8915662650602, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI38679950, Length=415, Percent_Identity=22.8915662650602, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI38679946, Length=415, Percent_Identity=22.8915662650602, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1789759, Length=376, Percent_Identity=41.7553191489362, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1788044, Length=361, Percent_Identity=42.382271468144, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI145693181, Length=400, Percent_Identity=36.25, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1789016, Length=396, Percent_Identity=33.0808080808081, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787560, Length=386, Percent_Identity=33.160621761658, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786349, Length=327, Percent_Identity=30.2752293577982, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786991, Length=417, Percent_Identity=27.3381294964029, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=384, Percent_Identity=35.6770833333333, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=32.258064516129, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI25144274, Length=376, Percent_Identity=31.3829787234043, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI71992977, Length=410, Percent_Identity=30.7317073170732, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI71981843, Length=193, Percent_Identity=31.0880829015544, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=23.6902050113895, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=35.7142857142857, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=33.5820895522388, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=346, Percent_Identity=26.5895953757225, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6321456, Length=366, Percent_Identity=25.4098360655738, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357415, Length=386, Percent_Identity=31.8652849740933, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI161085790, Length=408, Percent_Identity=31.6176470588235, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28574759, Length=408, Percent_Identity=31.6176470588235, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=31.1274509803922, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI281366494, Length=418, Percent_Identity=24.8803827751196, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24667139, Length=418, Percent_Identity=24.8803827751196, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24667143, Length=418, Percent_Identity=24.8803827751196, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42147; Mature: 42147

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLN
CHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHH
DIWHISNLFTNSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALKEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
CCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYV
CCCCCHHHHCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQKLQEELQHVECIQNIRGKGLMIGIECKHEVASFIEQLEKEGLLVLQAGPNVIRLLPPL
HHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCH
IVTNEELEQAVYMIKKVVCTKNVSII
HCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLN
CHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHH
DIWHISNLFTNSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALKEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
CCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYV
CCCCCHHHHCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQKLQEELQHVECIQNIRGKGLMIGIECKHEVASFIEQLEKEGLLVLQAGPNVIRLLPPL
HHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCH
IVTNEELEQAVYMIKKVVCTKNVSII
HCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]