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The map label for this gene is argF2 [H]

Identifier: 218905268

GI number: 218905268

Start: 3963872

End: 3964822

Strand: Reverse

Name: argF2 [H]

Synonym: BCAH820_4152

Alternate gene names: 218905268

Gene position: 3964822-3963872 (Counterclockwise)

Preceding gene: 218905269

Following gene: 218905267

Centisome position: 74.77

GC content: 36.91

Gene sequence:

>951_bases
ATGTCAACTGTACAAGTACCGAAATTAAATACGAAAGATCTTTTAACATTAGAAGAACTGACGCAAGAAGAAATCATTTC
TTTAATTGAGTTCGCTATCTATTTAAAAAAGAATAAGCAAGAGCCTTTATTACAAGGCAAAATATTAGGGCTTATCTTTG
ATAAACATTCAACTCGTACTCGCGTATCTTTTGAAGCAGGAATGGTACAGCTCGGAGGACATGGTATGTTTTTAAGTGGG
AAAGAGATGCAGATTGGAAGAGGGGAGAGTGTTTCAGATACTGCGAAAGTATTATCTCATTATATTGACGGGATCATGAT
ACGTACATTTTCACATGCCGATGTAGAAGAGTTTGCAAAAGAATCGAGCATACCTGTAATTAACGGTTTAACGGACGATC
ATCATCCTTGTCAAGCATTAGCAGACTTAATGACGATATATGAAGAAAAAAATACATTTGAAGGAATAAAATTGGCTTAC
GTAGGTGACGGAAATAATGTATGTCATTCATTGTTGTTAGCAAGTGCAAAAGTTGGAATGCATATGACTGTTGCAACGCC
TGTAGGGTATGAACCGAATGAGGAAATTGTAAAAAAAGCATTAGCGATTGCTGAAGAAACAGGAGCGAAAATTGAAATTT
TGCATAACCCTGAACTAGCGGTGAGTGAAGCAGATTTCATTTATGCTGACGTTTGGATGAGCATGGGGCAAGAGGGTGAA
GAAGAGAAATATACTTTATTTCAACCATACCAAATCAATAACGAACTTGTTAAGCATGCGAAACAAACATATCGTTTCTT
ACACTGTTTACCTGCCCATCGTGAAGAGGAAGTGACAGGAGAAATTATAGACGGACCACAGTCTATCGTTTTTGAGCAAG
CTGGTAATCGATTGCATGCGCAAAAAGCGTTATTAGTAAGTTTGTTTAAAAATGTAGAAGAGCTTTCCTAA

Upstream 100 bases:

>100_bases
ACCACTTATTGTGACGAATGAAGAGTTAGAACAGGCAGTATATATGATAAAAAAAGTAGTTTGTACAAAAAACGTATCAA
TTATATAAGGGGGAAATTTC

Downstream 100 bases:

>100_bases
ATGGTGTGCACCTCCAGTTGTTACGTACAAATAACAATTGGAGGTGCGCTTTTTTACATTGAAATGTCATATGTATATTT
AGTTAACCACTTCGATATCA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSTVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRTRVSFEAGMVQLGGHGMFLSG
KEMQIGRGESVSDTAKVLSHYIDGIMIRTFSHADVEEFAKESSIPVINGLTDDHHPCQALADLMTIYEEKNTFEGIKLAY
VGDGNNVCHSLLLASAKVGMHMTVATPVGYEPNEEIVKKALAIAEETGAKIEILHNPELAVSEADFIYADVWMSMGQEGE
EEKYTLFQPYQINNELVKHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHAQKALLVSLFKNVEELS

Sequences:

>Translated_316_residues
MSTVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRTRVSFEAGMVQLGGHGMFLSG
KEMQIGRGESVSDTAKVLSHYIDGIMIRTFSHADVEEFAKESSIPVINGLTDDHHPCQALADLMTIYEEKNTFEGIKLAY
VGDGNNVCHSLLLASAKVGMHMTVATPVGYEPNEEIVKKALAIAEETGAKIEILHNPELAVSEADFIYADVWMSMGQEGE
EEKYTLFQPYQINNELVKHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHAQKALLVSLFKNVEELS
>Mature_315_residues
STVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRTRVSFEAGMVQLGGHGMFLSGK
EMQIGRGESVSDTAKVLSHYIDGIMIRTFSHADVEEFAKESSIPVINGLTDDHHPCQALADLMTIYEEKNTFEGIKLAYV
GDGNNVCHSLLLASAKVGMHMTVATPVGYEPNEEIVKKALAIAEETGAKIEILHNPELAVSEADFIYADVWMSMGQEGEE
EKYTLFQPYQINNELVKHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHAQKALLVSLFKNVEELS

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=310, Percent_Identity=43.8709677419355, Blast_Score=268, Evalue=6e-72,
Organism=Homo sapiens, GI18105007, Length=310, Percent_Identity=29.0322580645161, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1790703, Length=324, Percent_Identity=37.6543209876543, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1786469, Length=327, Percent_Identity=37.6146788990826, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI2367364, Length=309, Percent_Identity=30.42071197411, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI48994908, Length=358, Percent_Identity=25.6983240223464, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI193204318, Length=172, Percent_Identity=34.8837209302326, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322373, Length=320, Percent_Identity=38.4375, Blast_Score=222, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6322331, Length=272, Percent_Identity=32.7205882352941, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24642586, Length=309, Percent_Identity=28.8025889967638, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35258; Mature: 35127

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEEEEECCCCCE
RVSFEAGMVQLGGHGMFLSGKEMQIGRGESVSDTAKVLSHYIDGIMIRTFSHADVEEFAK
EEEEECCEEEECCCEEEECCCCEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHH
ESSIPVINGLTDDHHPCQALADLMTIYEEKNTFEGIKLAYVGDGNNVCHSLLLASAKVGM
HCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCE
HMTVATPVGYEPNEEIVKKALAIAEETGAKIEILHNPELAVSEADFIYADVWMSMGQEGE
EEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCHHHHHHHHHCCCCCC
EEKYTLFQPYQINNELVKHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHA
CCCEEEECCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHCCHHHH
QKALLVSLFKNVEELS
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEEEEECCCCCE
RVSFEAGMVQLGGHGMFLSGKEMQIGRGESVSDTAKVLSHYIDGIMIRTFSHADVEEFAK
EEEEECCEEEECCCEEEECCCCEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHH
ESSIPVINGLTDDHHPCQALADLMTIYEEKNTFEGIKLAYVGDGNNVCHSLLLASAKVGM
HCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCE
HMTVATPVGYEPNEEIVKKALAIAEETGAKIEILHNPELAVSEADFIYADVWMSMGQEGE
EEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCHHHHHHHHHCCCCCC
EEKYTLFQPYQINNELVKHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHA
CCCEEEECCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHCCHHHH
QKALLVSLFKNVEELS
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA