Click here to switch to the map view.

The map label for this gene is mraY [H]

Identifier: 218905044

GI number: 218905044

Start: 3766762

End: 3767736

Strand: Reverse

Name: mraY [H]

Synonym: BCAH820_3928

Alternate gene names: 218905044

Gene position: 3767736-3766762 (Counterclockwise)

Preceding gene: 218905045

Following gene: 218905043

Centisome position: 71.05

GC content: 36.21

Gene sequence:

>975_bases
GTGCTTGAGCAAGGTTTATTAGTAACGGCTGGGGTAGCATTCTTAATTTCTGTTGCCCTTTCGCCATTGTTTATTCCATT
TTTAAGAAAATTAAAGTTCGGACAGAGTATTCGTGATGAGGGACCAAAGTCACATCAAAAAAAATCAGGAACACCGACAA
TGGGTGGTATTGTCATATATGTATCTATGATGGTAACTTCACTTATTATGGCGATTAAGTTTAATCATTTAGGTGCAGAA
GTTTCGTTATTACTATTAGTAACATTTGGTTACGGATTGATTGGGTTTTTAGATGACTACATAAAGGTAGTTAAGAAGAG
AAATCTTGGTTTGACATCAAAACAAAAATTAGTAGGTCAGCTTGTTATTGCAATTGCGTTCTTTTTAATTGGAAAAGGGC
AAGCGTTCCACACATACATTATGATTCCAGGAACGGATGTTAAGTTTGAATTAGGTTGGGCGTATTTTGTACTTGTACTA
TTTATGCTTATTGGTGGATCAAATGCAGTTAACTTAACTGACGGTTTAGATGGTTTATTATCAGGAACAGCTGCTATTGC
ATTTGGAGCTTTTAGTATTATTGCTGTTGCACAAGAGCAATTTGGCGTAGCGATATTCTGTATGGCGGTTGTAGGAGCTG
TACTTGGATTTTTAGTATTCAATGCGAATCCAGCGAAAGTGTTTATGGGAGATACAGGTTCTTTAGCTTTAGGTGGAGCT
ATTGCAGCCGTAGCAATTTTATTAAAACAAGAATTGCTACTTGTAATCATAGGCGGAGTATTCGTAATGGAAACTTTATC
GGTTATTATTCAGGTCATTTCATTTAAAACAACAGGAAAACGTGTCTTTAAAATGAGCCCATTACACCATCATTATGAAT
TATGTGGTTGGTCAGAGTGGCGTGTTGTTGTAACGTTTTGGTCTGTAGGATTTTTATTAGCTGTGTTAGGAATTTATATC
GGGGTGTGGATGTAA

Upstream 100 bases:

>100_bases
GGTAAAGATGTTCATCATTTTGACGATCGTGAAGTCGCTAAAGAAGCAATTACAGAGCGTTTAAACAACGAAGAGTAACA
ACGTGAGAGGAGGACTACAT

Downstream 100 bases:

>100_bases
TTGAAAACTGTAACTGAATTTCAAAATAAAAATATTCTTGTATTAGGCATTGCAAAAAGTGGTTATGCAGCAGCTACGCT
GTTACAAAAGTTAGGGGCAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNHLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYI
GVWM

Sequences:

>Translated_324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNHLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYI
GVWM
>Mature_324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNHLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYI
GVWM

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=326, Percent_Identity=47.5460122699387, Blast_Score=257, Evalue=6e-70,
Organism=Escherichia coli, GI1790218, Length=206, Percent_Identity=30.0970873786408, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 34907; Mature: 34907

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHCCCCCCCCHHHHHHH
VSMMVTSLIMAIKFNHLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVLFMLIGGSNAVNLTDGLDGLL
HHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
SGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCH
RVVVTFWSVGFLLAVLGIYIGVWM
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHCCCCCCCCHHHHHHH
VSMMVTSLIMAIKFNHLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVLFMLIGGSNAVNLTDGLDGLL
HHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
SGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCH
RVVVTFWSVGFLLAVLGIYIGVWM
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA