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The map label for this gene is rnhB [H]

Identifier: 218904966

GI number: 218904966

Start: 3688648

End: 3689421

Strand: Reverse

Name: rnhB [H]

Synonym: BCAH820_3850

Alternate gene names: 218904966

Gene position: 3689421-3688648 (Counterclockwise)

Preceding gene: 218904967

Following gene: 218904965

Centisome position: 69.58

GC content: 36.74

Gene sequence:

>774_bases
ATGCAAAAAGTGACGATTCAAGAAGCGGAACATTTACTGCAAGAAATTATAAGTGAAGAGGACGATCGCTTTCAAATATT
AATAAAAGATGAACGAAAAGGGGTACAAAAACTCATTTCGAAGTGGTATAAACAAAAAGAGTTAGCACAAAAGGAAAAAG
AAAAATTTCTAGAAATGTCTAAGTATGAAAATGCGTTACGTGAAAAAGGCCTTACATATATCGCAGGTATAGATGAAGTA
GGGCGTGGACCGCTAGCTGGACCTGTTGTGACGGCAGCTGTTATCCTTCCAGAAGATTTTTATATTCCAGGGTTAAATGA
TTCGAAAAAGCTGAGTGAGGCGAAGCGAGAGCGTTTTTATGGTGAGATTAAAGCAAAAGCAATCGCGATTGGAGTTGRGA
TTGTATCACCGCAAGTTATTGATGAGATAAATATTTATCAAGCGACGAAACAAGCGATGTTAGATGCTATTGCGAATTTA
TCTTGTACACCAGAATATTTATTAATTGATGCGATGAAACTTCCTACACCAATTCCGCAAACATCCATCATTAAAGGTGA
TGCGAAAAGTATTTCCATTTCAGCTGCATCCATTATTGCGAAAGTAACGAGAGATCGTATGATGAAAGAGCTTGGAGAAA
AGTATCCAGCATATGGATTTGAACAACATATGGGATATGGTACGAAACAACATTTAGAAGCGATTGAAGCACATGGAGTA
TTAGAAGAACATCGCAAATCGTTTGCGCCAATTAAAGATATGATTCAAAAATAA

Upstream 100 bases:

>100_bases
AGAGTTTGCAGAGCAGACAGAAGATGCAGAAAAAGTAGAAGAAGTATAAGACGTGCGTTTGTACGTCTTTTCTTTTTTGT
ATATAAAGGGAGTGGCATGA

Downstream 100 bases:

>100_bases
GCTGCGAAAACGCAGCTTATTTTTTATTTTCACATATAAACATTACTATTTTCAAAAAAGAATAAAGCGATTTCAGTTTT
CTGACACTTTATTGTAGACA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MQKVTIQEAEHLLQEIISEEDDRFQILIKDERKGVQKLISKWYKQKELAQKEKEKFLEMSKYENALREKGLTYIAGIDEV
GRGPLAGPVVTAAVILPEDFYIPGLNDSKKLSEAKRERFYGEIKAKAIAIGVXIVSPQVIDEINIYQATKQAMLDAIANL
SCTPEYLLIDAMKLPTPIPQTSIIKGDAKSISISAASIIAKVTRDRMMKELGEKYPAYGFEQHMGYGTKQHLEAIEAHGV
LEEHRKSFAPIKDMIQK

Sequences:

>Translated_257_residues
MQKVTIQEAEHLLQEIISEEDDRFQILIKDERKGVQKLISKWYKQKELAQKEKEKFLEMSKYENALREKGLTYIAGIDEV
GRGPLAGPVVTAAVILPEDFYIPGLNDSKKLSEAKRERFYGEIKAKAIAIGVXIVSPQVIDEINIYQATKQAMLDAIANL
SCTPEYLLIDAMKLPTPIPQTSIIKGDAKSISISAASIIAKVTRDRMMKELGEKYPAYGFEQHMGYGTKQHLEAIEAHGV
LEEHRKSFAPIKDMIQK
>Mature_257_residues
MQKVTIQEAEHLLQEIISEEDDRFQILIKDERKGVQKLISKWYKQKELAQKEKEKFLEMSKYENALREKGLTYIAGIDEV
GRGPLAGPVVTAAVILPEDFYIPGLNDSKKLSEAKRERFYGEIKAKAIAIGVXIVSPQVIDEINIYQATKQAMLDAIANL
SCTPEYLLIDAMKLPTPIPQTSIIKGDAKSISISAASIIAKVTRDRMMKELGEKYPAYGFEQHMGYGTKQHLEAIEAHGV
LEEHRKSFAPIKDMIQK

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=180, Percent_Identity=53.8888888888889, Blast_Score=185, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17536263, Length=241, Percent_Identity=30.2904564315353, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 28905; Mature: 28905

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVTIQEAEHLLQEIISEEDDRFQILIKDERKGVQKLISKWYKQKELAQKEKEKFLEMS
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYENALREKGLTYIAGIDEVGRGPLAGPVVTAAVILPEDFYIPGLNDSKKLSEAKRERFY
HHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
GEIKAKAIAIGVXIVSPQVIDEINIYQATKQAMLDAIANLSCTPEYLLIDAMKLPTPIPQ
HHHHHHHHEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
TSIIKGDAKSISISAASIIAKVTRDRMMKELGEKYPAYGFEQHMGYGTKQHLEAIEAHGV
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHH
LEEHRKSFAPIKDMIQK
HHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MQKVTIQEAEHLLQEIISEEDDRFQILIKDERKGVQKLISKWYKQKELAQKEKEKFLEMS
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYENALREKGLTYIAGIDEVGRGPLAGPVVTAAVILPEDFYIPGLNDSKKLSEAKRERFY
HHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
GEIKAKAIAIGVXIVSPQVIDEINIYQATKQAMLDAIANLSCTPEYLLIDAMKLPTPIPQ
HHHHHHHHEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
TSIIKGDAKSISISAASIIAKVTRDRMMKELGEKYPAYGFEQHMGYGTKQHLEAIEAHGV
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHH
LEEHRKSFAPIKDMIQK
HHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA