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The map label for this gene is soxA [H]

Identifier: 218884191

GI number: 218884191

Start: 842263

End: 843519

Strand: Reverse

Name: soxA [H]

Synonym: DKAM_0880

Alternate gene names: 218884191

Gene position: 843519-842263 (Counterclockwise)

Preceding gene: 218884192

Following gene: 218884190

Centisome position: 61.79

GC content: 46.06

Gene sequence:

>1257_bases
ATGGAGACCCTTGTATACGATGTAGTCGTCATCGGGGGAGGCCCTGCCGGGATAGCCTCAGCAATAAAAGCCGATAGCCT
TGGCTTGAAGACAGCACTGATAGAGAACAGGGATATACTTGGGGGAATACCGCTTCAATGCATACATCCCGGCTTTGGAA
TACACTACTTTAAGGAGGATTTAACAGGGACAGAGTTTATTGAGAGATTGATTGATAGACTCCGTGTATCCAGTGTAGAT
GTATATACTAAAACCCATGTCCACGCAATAGATGTAATAGCCCATGATGAGAAAATAGTGAACACGGTTAGAAGAAGCGG
TGTCACACGGTTTGTAGCAAAGACGATAATATATGCCACTGGTGCAAGAGAGAGACATCTATATGAAATAGGAGTAGTAG
GAGATAGACCCGGCTCAGGCATCTATACAGCTGGCGAGGCTCAGGCCTTAATGGATATCTATGGTGTCCTCCCAGGTAGA
GAAATAGTGATAATCGGCTCAGGCGATGTAGGACTCATAATGGCTAGGAGATTCAGTCTGGAAGGAGCCAGGGTAAAAGC
TGTAGTGGAGATGCTCCCGTATCCAGGTGGGTTAACTAGAAACATTGTGCAATGCCTCTACGACTTTAATATACCTCTTT
ACCTAGGACATGTGGTTACAGGGGTTAAGGGTAGAAACCGTGTAGAGAAAGTCATAGTGGCTAGAATCGGTGAAAACGGT
AAGCCGTTGAAAGAAACAGAGTTCGAGATACCCTGTGACACTGTGGTGGTTGCAGCTGGATTAATACCCAATGTAGGTTT
ACTCGAGAAAATAGGGGTTGCAATGGATCCCGCTACTAGGGGGCCGGTTGTAAACGAGCTCCTCGAAGCATCTATCCCAG
GTGTATTCGTAGCAGGTAACGCACTCATTATAAACGATCTAGTGGACTACGTCGTTGAGCAGGGTGAACTAGCTGCTAAA
GGAGCTAAGCTATTCATAGAGAATAATGGAGTACCATCAGTAGACTGGGTTAGAGTCGAGAAGGGCAGGAATATAAGGCT
AGTTGTACCACACTATATCAGCGGCGAGAGAGACGTGGTTATTTATGCCAGGGTTCAACAACCAGAGAGAAACGTGTATG
TCTCAATCCCTGAGATAGGGTACTTTATAAGGCTTACTAGTGTAAAGCCAGCTGAGATGCTTAGACTATGGATACCTGGG
AGAATCCTCTCCAGGGTCGATACTAGAAGGATAACACTGGAGGTGAAGCCGGCTTGA

Upstream 100 bases:

>100_bases
ATTGCTGGCTTGGAGGGTAAGGAGATGCATGAAGTTGTAGTCAAGATGGAGAGATATGGTTTGGGAGATGTTAAAAAGAT
GCTGAGAGAGGAAGCCTAGG

Downstream 100 bases:

>100_bases
CTACAAGGGAGTTAACCTGTATAGTATGCCCCATTGGATGCACGCTAAGAGTAACAATCCTCGGAGATGGCAACATAAAG
GTTGAGGGAGCTATGTGCAA

Product: NADH oxidase

Products: NA

Alternate protein names: Sarcosine oxidase subunit [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
METLVYDVVVIGGGPAGIASAIKADSLGLKTALIENRDILGGIPLQCIHPGFGIHYFKEDLTGTEFIERLIDRLRVSSVD
VYTKTHVHAIDVIAHDEKIVNTVRRSGVTRFVAKTIIYATGARERHLYEIGVVGDRPGSGIYTAGEAQALMDIYGVLPGR
EIVIIGSGDVGLIMARRFSLEGARVKAVVEMLPYPGGLTRNIVQCLYDFNIPLYLGHVVTGVKGRNRVEKVIVARIGENG
KPLKETEFEIPCDTVVVAAGLIPNVGLLEKIGVAMDPATRGPVVNELLEASIPGVFVAGNALIINDLVDYVVEQGELAAK
GAKLFIENNGVPSVDWVRVEKGRNIRLVVPHYISGERDVVIYARVQQPERNVYVSIPEIGYFIRLTSVKPAEMLRLWIPG
RILSRVDTRRITLEVKPA

Sequences:

>Translated_418_residues
METLVYDVVVIGGGPAGIASAIKADSLGLKTALIENRDILGGIPLQCIHPGFGIHYFKEDLTGTEFIERLIDRLRVSSVD
VYTKTHVHAIDVIAHDEKIVNTVRRSGVTRFVAKTIIYATGARERHLYEIGVVGDRPGSGIYTAGEAQALMDIYGVLPGR
EIVIIGSGDVGLIMARRFSLEGARVKAVVEMLPYPGGLTRNIVQCLYDFNIPLYLGHVVTGVKGRNRVEKVIVARIGENG
KPLKETEFEIPCDTVVVAAGLIPNVGLLEKIGVAMDPATRGPVVNELLEASIPGVFVAGNALIINDLVDYVVEQGELAAK
GAKLFIENNGVPSVDWVRVEKGRNIRLVVPHYISGERDVVIYARVQQPERNVYVSIPEIGYFIRLTSVKPAEMLRLWIPG
RILSRVDTRRITLEVKPA
>Mature_418_residues
METLVYDVVVIGGGPAGIASAIKADSLGLKTALIENRDILGGIPLQCIHPGFGIHYFKEDLTGTEFIERLIDRLRVSSVD
VYTKTHVHAIDVIAHDEKIVNTVRRSGVTRFVAKTIIYATGARERHLYEIGVVGDRPGSGIYTAGEAQALMDIYGVLPGR
EIVIIGSGDVGLIMARRFSLEGARVKAVVEMLPYPGGLTRNIVQCLYDFNIPLYLGHVVTGVKGRNRVEKVIVARIGENG
KPLKETEFEIPCDTVVVAAGLIPNVGLLEKIGVAMDPATRGPVVNELLEASIPGVFVAGNALIINDLVDYVVEQGELAAK
GAKLFIENNGVPSVDWVRVEKGRNIRLVVPHYISGERDVVIYARVQQPERNVYVSIPEIGYFIRLTSVKPAEMLRLWIPG
RILSRVDTRRITLEVKPA

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=372, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006277 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C; PF07992 Pyr_redox_2 [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45654; Mature: 45654

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLVYDVVVIGGGPAGIASAIKADSLGLKTALIENRDILGGIPLQCIHPGFGIHYFKED
CCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCCCCEEHHHHC
LTGTEFIERLIDRLRVSSVDVYTKTHVHAIDVIAHDEKIVNTVRRSGVTRFVAKTIIYAT
CCHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCHHHHHHHHHCCHHHHHHHHHHEEC
GARERHLYEIGVVGDRPGSGIYTAGEAQALMDIYGVLPGREIVIIGSGDVGLIMARRFSL
CCCCCEEEEEEEEECCCCCCCEECCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECC
EGARVKAVVEMLPYPGGLTRNIVQCLYDFNIPLYLGHVVTGVKGRNRVEKVIVARIGENG
CCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCCCCHHHHHHHHHHCCCCC
KPLKETEFEIPCDTVVVAAGLIPNVGLLEKIGVAMDPATRGPVVNELLEASIPGVFVAGN
CCCCCCCCCCCCHHHHHHHCCCCCCCHHHHCCCEECCCCCCHHHHHHHHHCCCCEEEECC
ALIINDLVDYVVEQGELAAKGAKLFIENNGVPSVDWVRVEKGRNIRLVVPHYISGERDVV
EEEHHHHHHHHHCCCCEEECCEEEEEECCCCCCEEEEEEECCCEEEEEECCCCCCCCCEE
IYARVQQPERNVYVSIPEIGYFIRLTSVKPAEMLRLWIPGRILSRVDTRRITLEVKPA
EEEEECCCCCCEEEEECCCCEEEEEECCCHHHHHEEECCHHHHHCCCCEEEEEEEECC
>Mature Secondary Structure
METLVYDVVVIGGGPAGIASAIKADSLGLKTALIENRDILGGIPLQCIHPGFGIHYFKED
CCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCCCCEEHHHHC
LTGTEFIERLIDRLRVSSVDVYTKTHVHAIDVIAHDEKIVNTVRRSGVTRFVAKTIIYAT
CCHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCHHHHHHHHHCCHHHHHHHHHHEEC
GARERHLYEIGVVGDRPGSGIYTAGEAQALMDIYGVLPGREIVIIGSGDVGLIMARRFSL
CCCCCEEEEEEEEECCCCCCCEECCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECC
EGARVKAVVEMLPYPGGLTRNIVQCLYDFNIPLYLGHVVTGVKGRNRVEKVIVARIGENG
CCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCCCCHHHHHHHHHHCCCCC
KPLKETEFEIPCDTVVVAAGLIPNVGLLEKIGVAMDPATRGPVVNELLEASIPGVFVAGN
CCCCCCCCCCCCHHHHHHHCCCCCCCHHHHCCCEECCCCCCHHHHHHHHHCCCCEEEECC
ALIINDLVDYVVEQGELAAKGAKLFIENNGVPSVDWVRVEKGRNIRLVVPHYISGERDVV
EEEHHHHHHHHHCCCCEEECCEEEEEECCCCCCEEEEEEECCCEEEEEECCCCCCCCCEE
IYARVQQPERNVYVSIPEIGYFIRLTSVKPAEMLRLWIPGRILSRVDTRRITLEVKPA
EEEEECCCCCCEEEEECCCCEEEEEECCCHHHHHEEECCHHHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]