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The map label for this gene is 218884123

Identifier: 218884123

GI number: 218884123

Start: 780890

End: 781438

Strand: Reverse

Name: 218884123

Synonym: DKAM_0812

Alternate gene names: NA

Gene position: 781438-780890 (Counterclockwise)

Preceding gene: 218884124

Following gene: 218884122

Centisome position: 57.24

GC content: 44.63

Gene sequence:

>549_bases
ATGAAAATCATTATTACAGGCCGCCCCGGTGTGGGTAAGTCGACGTTTTTCGAGAAGTTAATATCAGAGCTCAGAGAGAA
CAATCTATTGGTTGGCGGTATTAAAGCGCCTGAAGTAAGGGAACATGGTGTGAGGGTAGGGTTTAAAGTTATTGATTTAT
TAAGTGGTGAAAAAGCATGGTTAGCAAAAAAGAGTATCCCTGGTTCGGTGAGGATAGGGTCTTATACTGTGCTCGTTGAA
GAGGCATCCAGGATCATTGAGACAGCGTTAAGGAGGGCTCTTGGAGAAGCCAGCGTCATAGGTATAGATGAAGTGGGGCC
CATGGAGCTTAAAATACCTGTTTTCAAGCCATTGCTCCTGGAGATCCTCGACTCCGGTAAACCAGTCATACTTGTCGTAC
ATTATAGATTGACCGATAGAGATGTACTGGGTAGACTTAGTGACGCCGAAAAAATAGTGTTAACTATGGAGAACAGGGAG
CACGTTAAATCAAGTACGAAGGGGTTGATTAATAAAGTAATCGAGGCCCTGGCTCCGTCTCGATCCTGA

Upstream 100 bases:

>100_bases
GAAGTCAGGCCCAGGTTGAGTGGCACGATGCATATTTAAACCCATCAATCTATGGGCTTCCATGGATCACTAGCCAGGTT
CTAAAGTAAAGGGGGGATTC

Downstream 100 bases:

>100_bases
GGGAGGATCTCAACCGTGGAGATATGGGGACAAACGGTGGTGTATAGTCAATGACTGAAGTAAAGATACTCAGCCGTGAA
CAATTGATCCAGGAGGGATT

Product: putative nucleotide kinase

Products: NA

Alternate protein names: NTPase THEP1; Nucleoside triphosphate phosphohydrolase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKIIITGRPGVGKSTFFEKLISELRENNLLVGGIKAPEVREHGVRVGFKVIDLLSGEKAWLAKKSIPGSVRIGSYTVLVE
EASRIIETALRRALGEASVIGIDEVGPMELKIPVFKPLLLEILDSGKPVILVVHYRLTDRDVLGRLSDAEKIVLTMENRE
HVKSSTKGLINKVIEALAPSRS

Sequences:

>Translated_182_residues
MKIIITGRPGVGKSTFFEKLISELRENNLLVGGIKAPEVREHGVRVGFKVIDLLSGEKAWLAKKSIPGSVRIGSYTVLVE
EASRIIETALRRALGEASVIGIDEVGPMELKIPVFKPLLLEILDSGKPVILVVHYRLTDRDVLGRLSDAEKIVLTMENRE
HVKSSTKGLINKVIEALAPSRS
>Mature_182_residues
MKIIITGRPGVGKSTFFEKLISELRENNLLVGGIKAPEVREHGVRVGFKVIDLLSGEKAWLAKKSIPGSVRIGSYTVLVE
EASRIIETALRRALGEASVIGIDEVGPMELKIPVFKPLLLEILDSGKPVILVVHYRLTDRDVLGRLSDAEKIVLTMENRE
HVKSSTKGLINKVIEALAPSRS

Specific function: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency [H]

COG id: COG1618

COG function: function code F; Predicted nucleotide kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the THEP1 NTPase family [H]

Homologues:

Organism=Drosophila melanogaster, GI85726488, Length=144, Percent_Identity=30.5555555555556, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004948 [H]

Pfam domain/function: PF03266 DUF265 [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 19957; Mature: 19957

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIITGRPGVGKSTFFEKLISELRENNLLVGGIKAPEVREHGVRVGFKVIDLLSGEKAW
CEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHCCHHHHHHHHHHHCCCHHH
LAKKSIPGSVRIGSYTVLVEEASRIIETALRRALGEASVIGIDEVGPMELKIPVFKPLLL
HECCCCCCCEEECEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECHHHHHHHH
EILDSGKPVILVVHYRLTDRDVLGRLSDAEKIVLTMENREHVKSSTKGLINKVIEALAPS
HHHCCCCCEEEEEEEEECCHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCC
RS
CC
>Mature Secondary Structure
MKIIITGRPGVGKSTFFEKLISELRENNLLVGGIKAPEVREHGVRVGFKVIDLLSGEKAW
CEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHCCHHHHHHHHHHHCCCHHH
LAKKSIPGSVRIGSYTVLVEEASRIIETALRRALGEASVIGIDEVGPMELKIPVFKPLLL
HECCCCCCCEEECEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECHHHHHHHH
EILDSGKPVILVVHYRLTDRDVLGRLSDAEKIVLTMENREHVKSSTKGLINKVIEALAPS
HHHCCCCCEEEEEEEEECCHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCC
RS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA