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The map label for this gene is cysS [H]

Identifier: 218884115

GI number: 218884115

Start: 774242

End: 775687

Strand: Direct

Name: cysS [H]

Synonym: DKAM_0804

Alternate gene names: 218884115

Gene position: 774242-775687 (Clockwise)

Preceding gene: 218884114

Following gene: 218884116

Centisome position: 56.71

GC content: 46.2

Gene sequence:

>1446_bases
TTGGGAGGCATGCTTCCAGCTATAAAAATATATGATACTTTATCCAGGGATTTAAAGGAGCTGCAGCCCATTGAGCCAGG
CATAGTTAAAATGTATGTATGCGGGCCAACAGTCTATGATTATACACATATAGGGCATGGGAAGACGTATGTTATATACG
ATGCGTTCAAGAGGTATCTTTCTCTAAGGGGATACCACGTAGTCCACGTCATGAATATCACTGATATAGATGATAAGATC
ATAAAGCGCTCCCAGGATGAGGGTAGGGATTGGAGTGAAATCGTGGATGAATACACACGCGACTATTTATCAGCCCTGGA
GAAATTGAATGTGACAATAGATCATCATCCACGTGTTTCAGAGCACATCAATGAGATAATAGGCTTCATCCAGGGGTTAA
TAGACAAGGGGTATGCCTATATCGCATCCAGTGGAAGCGTATACTTCAATGTAGACAAGTACGATGACTATGGCCACTTA
TCCGGTAGAGTGAGTAAGGAGACATGGGGCCAGGAGCAGGAGTTCCTCTCAGAGAAACGGAACCCATACGACTTCGCCCT
CTGGAAGGCTGCCAAGCCTGGTGAACCATACTGGGAGAGCCCGTGGGGAAGGGGTAGGCCTGGATGGCATATAGAATGCA
GTGTTATGAGTAGCCGATACCTGGGCTCCAGGTTCGATATACATGGCGGTGGAACCGACCTGATATTTCCACACCACGAG
AACGAGAGGGCTCAGAGCGAGGCTTTCTTCGGGTCTAAGCCATGGGTAAGCATATGGATGCATTCAGGGCTTGTAATGGT
TGGCAAGGATAAGATGAGTAAGAGCCTTAAGAATATTATACCGTTAAAGGAGGCATTCAATAAATGGGGTCCCATGCCCC
TGAGGCTCTGGTATCTCTCAACGCATTACAGGAAGCCGCTATATTTCTCCGAGGAGGCTCTCGAAAACTCTGTGAAACTA
TATGAGAGACTAACTACAGCAGCCCAGCTACTGAGGAGGCTGGCCCATGAGTCAACAGGCCTACACTATGCACGCGAGGA
GGACTTGAAGGTGTTTAACCAGCTTGTATCACTCCACACGCGCTTCCATAACGCGTTAAGCGATGACTTTAACACGGCGG
AGGCTCTTGCAGTGGTTAACGAGTACCTTACAATATTATTCAGGGATATACAGTATAATCCAAGACACCTACTTGTATCA
ACAAGCATAAAGTTACTCAGGGAATTCAATACAGTGCTCGGCGTACTAGATAGGGAGCTGGAAGGAGTGGAGGAGAGTGA
GGCATTACTGGATAGCATGGTAGAGATACTTATAAATGTCAGGAAGGAGCTCAGAAAGAGAGGCATATACGACTTATCAG
ACACTATAAGAAGCGACTTATCAAAGATAGGTATACAGCTAATGGATAAGGGGCTTGAAACAACGTGGGTAAGGGTTAGA
AAGTGA

Upstream 100 bases:

>100_bases
GAAGCTATGAAGAAATACTTGACTACGGAGGAGCTGGCCGAGGTCTTCTTAAAGGTTGCGAAGCTGGTTCTCGATGTCTT
CCACAAGTATTATTGAAGGA

Downstream 100 bases:

>100_bases
GTATTAGTTCCAGTAGAAAATGGCGAAGCAGTGAGCTAATAGCGTTAGAATACCTTGAGAAACAAGGATTTAGAATCGAG
GAAACGAGGAAGAAGATAAA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MGGMLPAIKIYDTLSRDLKELQPIEPGIVKMYVCGPTVYDYTHIGHGKTYVIYDAFKRYLSLRGYHVVHVMNITDIDDKI
IKRSQDEGRDWSEIVDEYTRDYLSALEKLNVTIDHHPRVSEHINEIIGFIQGLIDKGYAYIASSGSVYFNVDKYDDYGHL
SGRVSKETWGQEQEFLSEKRNPYDFALWKAAKPGEPYWESPWGRGRPGWHIECSVMSSRYLGSRFDIHGGGTDLIFPHHE
NERAQSEAFFGSKPWVSIWMHSGLVMVGKDKMSKSLKNIIPLKEAFNKWGPMPLRLWYLSTHYRKPLYFSEEALENSVKL
YERLTTAAQLLRRLAHESTGLHYAREEDLKVFNQLVSLHTRFHNALSDDFNTAEALAVVNEYLTILFRDIQYNPRHLLVS
TSIKLLREFNTVLGVLDRELEGVEESEALLDSMVEILINVRKELRKRGIYDLSDTIRSDLSKIGIQLMDKGLETTWVRVR
K

Sequences:

>Translated_481_residues
MGGMLPAIKIYDTLSRDLKELQPIEPGIVKMYVCGPTVYDYTHIGHGKTYVIYDAFKRYLSLRGYHVVHVMNITDIDDKI
IKRSQDEGRDWSEIVDEYTRDYLSALEKLNVTIDHHPRVSEHINEIIGFIQGLIDKGYAYIASSGSVYFNVDKYDDYGHL
SGRVSKETWGQEQEFLSEKRNPYDFALWKAAKPGEPYWESPWGRGRPGWHIECSVMSSRYLGSRFDIHGGGTDLIFPHHE
NERAQSEAFFGSKPWVSIWMHSGLVMVGKDKMSKSLKNIIPLKEAFNKWGPMPLRLWYLSTHYRKPLYFSEEALENSVKL
YERLTTAAQLLRRLAHESTGLHYAREEDLKVFNQLVSLHTRFHNALSDDFNTAEALAVVNEYLTILFRDIQYNPRHLLVS
TSIKLLREFNTVLGVLDRELEGVEESEALLDSMVEILINVRKELRKRGIYDLSDTIRSDLSKIGIQLMDKGLETTWVRVR
K
>Mature_480_residues
GGMLPAIKIYDTLSRDLKELQPIEPGIVKMYVCGPTVYDYTHIGHGKTYVIYDAFKRYLSLRGYHVVHVMNITDIDDKII
KRSQDEGRDWSEIVDEYTRDYLSALEKLNVTIDHHPRVSEHINEIIGFIQGLIDKGYAYIASSGSVYFNVDKYDDYGHLS
GRVSKETWGQEQEFLSEKRNPYDFALWKAAKPGEPYWESPWGRGRPGWHIECSVMSSRYLGSRFDIHGGGTDLIFPHHEN
ERAQSEAFFGSKPWVSIWMHSGLVMVGKDKMSKSLKNIIPLKEAFNKWGPMPLRLWYLSTHYRKPLYFSEEALENSVKLY
ERLTTAAQLLRRLAHESTGLHYAREEDLKVFNQLVSLHTRFHNALSDDFNTAEALAVVNEYLTILFRDIQYNPRHLLVST
SIKLLREFNTVLGVLDRELEGVEESEALLDSMVEILINVRKELRKRGIYDLSDTIRSDLSKIGIQLMDKGLETTWVRVRK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=507, Percent_Identity=34.3195266272189, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI21269877, Length=418, Percent_Identity=34.4497607655502, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI10835051, Length=418, Percent_Identity=34.4497607655502, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI303304987, Length=418, Percent_Identity=34.4497607655502, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI62240992, Length=418, Percent_Identity=34.4497607655502, Blast_Score=221, Evalue=1e-57,
Organism=Escherichia coli, GI1786737, Length=479, Percent_Identity=41.1273486430063, Blast_Score=343, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI17509795, Length=442, Percent_Identity=31.9004524886878, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17509797, Length=442, Percent_Identity=31.9004524886878, Blast_Score=223, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6324082, Length=405, Percent_Identity=35.0617283950617, Blast_Score=221, Evalue=2e-58,
Organism=Drosophila melanogaster, GI19922218, Length=512, Percent_Identity=36.5234375, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI19922364, Length=400, Percent_Identity=34.25, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 55707; Mature: 55576

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGMLPAIKIYDTLSRDLKELQPIEPGIVKMYVCGPTVYDYTHIGHGKTYVIYDAFKRYL
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEECCCCCEEEEHHHHHHHH
SLRGYHVVHVMNITDIDDKIIKRSQDEGRDWSEIVDEYTRDYLSALEKLNVTIDHHPRVS
HCCCEEEEEEEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCHH
EHINEIIGFIQGLIDKGYAYIASSGSVYFNVDKYDDYGHLSGRVSKETWGQEQEFLSEKR
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHCC
NPYDFALWKAAKPGEPYWESPWGRGRPGWHIECSVMSSRYLGSRFDIHGGGTDLIFPHHE
CCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCEEEECCCCCCEECCCCC
NERAQSEAFFGSKPWVSIWMHSGLVMVGKDKMSKSLKNIIPLKEAFNKWGPMPLRLWYLS
CCHHHHHHCCCCCCCEEEEECCCEEEECHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEH
THYRKPLYFSEEALENSVKLYERLTTAAQLLRRLAHESTGLHYAREEDLKVFNQLVSLHT
HHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
RFHNALSDDFNTAEALAVVNEYLTILFRDIQYNPRHLLVSTSIKLLREFNTVLGVLDREL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
EGVEESEALLDSMVEILINVRKELRKRGIYDLSDTIRSDLSKIGIQLMDKGLETTWVRVR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
K
C
>Mature Secondary Structure 
GGMLPAIKIYDTLSRDLKELQPIEPGIVKMYVCGPTVYDYTHIGHGKTYVIYDAFKRYL
CCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEECCCCCEEEEHHHHHHHH
SLRGYHVVHVMNITDIDDKIIKRSQDEGRDWSEIVDEYTRDYLSALEKLNVTIDHHPRVS
HCCCEEEEEEEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCHH
EHINEIIGFIQGLIDKGYAYIASSGSVYFNVDKYDDYGHLSGRVSKETWGQEQEFLSEKR
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHCC
NPYDFALWKAAKPGEPYWESPWGRGRPGWHIECSVMSSRYLGSRFDIHGGGTDLIFPHHE
CCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCEEEECCCCCCEECCCCC
NERAQSEAFFGSKPWVSIWMHSGLVMVGKDKMSKSLKNIIPLKEAFNKWGPMPLRLWYLS
CCHHHHHHCCCCCCCEEEEECCCEEEECHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEH
THYRKPLYFSEEALENSVKLYERLTTAAQLLRRLAHESTGLHYAREEDLKVFNQLVSLHT
HHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
RFHNALSDDFNTAEALAVVNEYLTILFRDIQYNPRHLLVSTSIKLLREFNTVLGVLDREL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
EGVEESEALLDSMVEILINVRKELRKRGIYDLSDTIRSDLSKIGIQLMDKGLETTWVRVR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA