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The map label for this gene is ygjE [C]

Identifier: 218884071

GI number: 218884071

Start: 732488

End: 733216

Strand: Reverse

Name: ygjE [C]

Synonym: DKAM_0760

Alternate gene names: 218884071

Gene position: 733216-732488 (Counterclockwise)

Preceding gene: 218884072

Following gene: 218884070

Centisome position: 53.71

GC content: 52.4

Gene sequence:

>729_bases
TTGCTCTACCCGCCTGAGCGGGAGGTCAAGACAGTGAGCAGGGAGGCGATTGAAAGAGAGCTCAGGAGCATGGGGCCCCT
TACGCTGGTGCAAAAGAGGACCATAGCGTTGATGGCGCTTGCAGTCATACTCTGGCTCATTGAGCCGCTCGCAGTTTTGC
TGCTAAGCGGACAGCAGTGGGTACTTGACTGGACCTACGTGGTCTCGCTGCTGGTAATAATGCTATTCTTCATGCCTGGC
ATTGGCGTCCTAGAGGCTAAGCAGATAAGTGAACTGGACTGGGGAGTAGTGTTCCTCGTAGCGGGCGGACTCGCTCTCGG
CGAGGGACTCAGGGAGACGGGTATTCTCAAGTTAATCGCCGACTCTCTGAAGAGCCCACTTCAGGCCTATCCACCGAGCC
TCGTCTCAGTAATAATTGCAGCTATATCGGTTCTGAGCATTACTGTAATATGTAGCATAACAGCAACTAGTGCAACAATG
GTTCCACTTGCCATTAGCGTGGCAAAGACGCTGGGTATGGACCCCAGGACAAGCGCGGTGGTTGCAGTAGCAGCTGGGCT
TGCCTCGTGCTACGCCTTCCTGCTCCCAGCAAATACACCCCCAAACGCTATAACGTACTCCTACGGCTACTTCAAGAGCT
ATGAAATGGCTAAGGCAGGCGTTATCGTCATACTTGCAGGCATAGCACTAATAATCGTTATAATGCCTCTAGTATCCCTA
TTGATTTAG

Upstream 100 bases:

>100_bases
GAGAGCTCCTTGGGAATCAGGATAAGCTTTGTAAAGTGGATGATATGGGGGGGTTCCAATAGTGCTTGCACTGACTCTAA
CTGCCTGGAGAGTTCTCCTA

Downstream 100 bases:

>100_bases
GAGGGTTTTTAAATTAAGATACCTGGTAGGGGTTAATTGATCGTAAAAAGGTGTCTTCGATGGATGCTGGGAGATGCCTT
ATAATAGCGAGGTTTCAGCC

Product: anion transporter

Products: tartrate [Cytoplasm]; succinate [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MLYPPEREVKTVSREAIERELRSMGPLTLVQKRTIALMALAVILWLIEPLAVLLLSGQQWVLDWTYVVSLLVIMLFFMPG
IGVLEAKQISELDWGVVFLVAGGLALGEGLRETGILKLIADSLKSPLQAYPPSLVSVIIAAISVLSITVICSITATSATM
VPLAISVAKTLGMDPRTSAVVAVAAGLASCYAFLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLVSL
LI

Sequences:

>Translated_242_residues
MLYPPEREVKTVSREAIERELRSMGPLTLVQKRTIALMALAVILWLIEPLAVLLLSGQQWVLDWTYVVSLLVIMLFFMPG
IGVLEAKQISELDWGVVFLVAGGLALGEGLRETGILKLIADSLKSPLQAYPPSLVSVIIAAISVLSITVICSITATSATM
VPLAISVAKTLGMDPRTSAVVAVAAGLASCYAFLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLVSL
LI
>Mature_242_residues
MLYPPEREVKTVSREAIERELRSMGPLTLVQKRTIALMALAVILWLIEPLAVLLLSGQQWVLDWTYVVSLLVIMLFFMPG
IGVLEAKQISELDWGVVFLVAGGLALGEGLRETGILKLIADSLKSPLQAYPPSLVSVIIAAISVLSITVICSITATSATM
VPLAISVAKTLGMDPRTSAVVAVAAGLASCYAFLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLVSL
LI

Specific function: Responsible For The Uptake Of Tartrate In Exchange To The Efflux Of Succinate (Potential). [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=256, Percent_Identity=26.953125, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI4506979, Length=252, Percent_Identity=28.968253968254, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI225637549, Length=252, Percent_Identity=28.968253968254, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI225637552, Length=252, Percent_Identity=28.968253968254, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI19923838, Length=156, Percent_Identity=34.6153846153846, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI31377715, Length=259, Percent_Identity=25.4826254826255, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI301069346, Length=259, Percent_Identity=25.4826254826255, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI58761541, Length=259, Percent_Identity=25.4826254826255, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI301069353, Length=253, Percent_Identity=25.296442687747, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI31795546, Length=140, Percent_Identity=32.8571428571429, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI301069349, Length=228, Percent_Identity=25.8771929824561, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1789444, Length=239, Percent_Identity=28.4518828451883, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786829, Length=241, Percent_Identity=25.3112033195021, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71989118, Length=244, Percent_Identity=28.2786885245902, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71988385, Length=160, Percent_Identity=34.375, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32565804, Length=160, Percent_Identity=34.375, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551790, Length=255, Percent_Identity=23.5294117647059, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45551633, Length=241, Percent_Identity=24.896265560166, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281366409, Length=241, Percent_Identity=24.896265560166, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737623, Length=241, Percent_Identity=24.896265560166, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666468, Length=241, Percent_Identity=24.896265560166, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 25828; Mature: 25828

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPPEREVKTVSREAIERELRSMGPLTLVQKRTIALMALAVILWLIEPLAVLLLSGQQW
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VLDWTYVVSLLVIMLFFMPGIGVLEAKQISELDWGVVFLVAGGLALGEGLRETGILKLIA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
DSLKSPLQAYPPSLVSVIIAAISVLSITVICSITATSATMVPLAISVAKTLGMDPRTSAV
HHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHH
VAVAAGLASCYAFLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLVSL
HHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LI
HC
>Mature Secondary Structure
MLYPPEREVKTVSREAIERELRSMGPLTLVQKRTIALMALAVILWLIEPLAVLLLSGQQW
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VLDWTYVVSLLVIMLFFMPGIGVLEAKQISELDWGVVFLVAGGLALGEGLRETGILKLIA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
DSLKSPLQAYPPSLVSVIIAAISVLSITVICSITATSATMVPLAISVAKTLGMDPRTSAV
HHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHH
VAVAAGLASCYAFLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLVSL
HHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LI
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: tartrate [Periplasm]; succinate [Cytoplasm] [C]

Specific reaction: tartrate [Periplasm] + succinate [Cytoplasm] = tartrate [Cytoplasm] + succinate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]