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The map label for this gene is sdcS [H]

Identifier: 218884072

GI number: 218884072

Start: 733200

End: 733913

Strand: Reverse

Name: sdcS [H]

Synonym: DKAM_0761

Alternate gene names: 218884072

Gene position: 733913-733200 (Counterclockwise)

Preceding gene: 218884080

Following gene: 218884071

Centisome position: 53.76

GC content: 51.4

Gene sequence:

>714_bases
ATGAATACCAGACTAAAGCTCCTTATAGCTGTGTTAACGCTCATGACAGCTCATTTAGTGGCGTCGGCATCGCCCATAGG
TGGGCTGGATCAGAGAGGTATGGCGATGCTGGGAATAGCCCTACTGGCACTCGTGTACTGGTCTACGGAGTGCGTTCCAA
TACCAGTAACAGGCCTCATAGTAATGTTGTTGCTCACGCTATACGGCATCTTTCCCTTCTCCAAGTCCGTGTCCTTCATA
GCAAGTAAGGTGAACATACTCATCATAGCCGGCCTCGTGATATCTGCCGCGCTCTCCACACATAAGCTCGACAAGCTCCT
GGGACTCAAAGTGCTCTCCCTAGTTGGAGTCAGGGTGCATATGGTAGTGCTTGGAATGATGCTTGCAACAGCCCTTATAT
CGATGTTGATGTCAAACACAGCTGCAGCGGCCCTCATGGCCCCCGTCGCAGTAAGCATTCTCAGCATGGTGGGTGCTAAG
TCAGGGGAGAGCAACCTTGGTAAGGCCTTAATGATAGGCATCGCATATGCAGCAACAATAGGCGGTATAGGAACGCCTGT
GGGCACGCCGCCCGTGCCAATAACGATTGGAAACATCGAGAGCTCCTTGGGAATCAGGATAAGCTTTGTAAAGTGGATGA
TATGGGGGGGTTCCAATAGTGCTTGCACTGACTCTAACTGCCTGGAGAGTTCTCCTATTGCTCTACCCGCCTGA

Upstream 100 bases:

>100_bases
GAAGCCGGGGTGGCCTACAGGGGACCACGATCTTTTTATACTCCTGCTTCCAATTCATTTGTACTAGCCTACATGAAGGA
GTAATGTGGGGTTTAGTGTC

Downstream 100 bases:

>100_bases
GCGGGAGGTCAAGACAGTGAGCAGGGAGGCGATTGAAAGAGAGCTCAGGAGCATGGGGCCCCTTACGCTGGTGCAAAAGA
GGACCATAGCGTTGATGGCG

Product: anion transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNTRLKLLIAVLTLMTAHLVASASPIGGLDQRGMAMLGIALLALVYWSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFI
ASKVNILIIAGLVISAALSTHKLDKLLGLKVLSLVGVRVHMVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAK
SGESNLGKALMIGIAYAATIGGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGGSNSACTDSNCLESSPIALPA

Sequences:

>Translated_237_residues
MNTRLKLLIAVLTLMTAHLVASASPIGGLDQRGMAMLGIALLALVYWSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFI
ASKVNILIIAGLVISAALSTHKLDKLLGLKVLSLVGVRVHMVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAK
SGESNLGKALMIGIAYAATIGGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGGSNSACTDSNCLESSPIALPA
>Mature_237_residues
MNTRLKLLIAVLTLMTAHLVASASPIGGLDQRGMAMLGIALLALVYWSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFI
ASKVNILIIAGLVISAALSTHKLDKLLGLKVLSLVGVRVHMVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAK
SGESNLGKALMIGIAYAATIGGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGGSNSACTDSNCLESSPIALPA

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI31377715, Length=136, Percent_Identity=37.5, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI301069346, Length=136, Percent_Identity=37.5, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI301069349, Length=118, Percent_Identity=39.8305084745763, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI58761541, Length=118, Percent_Identity=39.8305084745763, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4506979, Length=236, Percent_Identity=28.3898305084746, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI219802232, Length=129, Percent_Identity=34.1085271317829, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI29171306, Length=132, Percent_Identity=34.0909090909091, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI19923838, Length=118, Percent_Identity=32.2033898305085, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI225637549, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI225637552, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551790, Length=207, Percent_Identity=29.951690821256, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71988385, Length=148, Percent_Identity=29.7297297297297, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32564681, Length=245, Percent_Identity=27.7551020408163, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32565804, Length=183, Percent_Identity=27.8688524590164, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324340, Length=191, Percent_Identity=29.3193717277487, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281362114, Length=185, Percent_Identity=29.1891891891892, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362112, Length=185, Percent_Identity=29.1891891891892, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362116, Length=185, Percent_Identity=29.1891891891892, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281366409, Length=187, Percent_Identity=25.1336898395722, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737623, Length=187, Percent_Identity=25.1336898395722, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666468, Length=187, Percent_Identity=25.1336898395722, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551633, Length=187, Percent_Identity=25.1336898395722, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 24399; Mature: 24399

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRLKLLIAVLTLMTAHLVASASPIGGLDQRGMAMLGIALLALVYWSTECVPIPVTGLI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VMLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTHKLDKLLGLKVLSLVGVRVH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAKSGESNLGKALMIGIAYAATI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGGSNSACTDSNCLESSPIALPA
CCCCCCCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNTRLKLLIAVLTLMTAHLVASASPIGGLDQRGMAMLGIALLALVYWSTECVPIPVTGLI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VMLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTHKLDKLLGLKVLSLVGVRVH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAKSGESNLGKALMIGIAYAATI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGGSNSACTDSNCLESSPIALPA
CCCCCCCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA