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The map label for this gene is ydjH [H]

Identifier: 218883926

GI number: 218883926

Start: 582445

End: 583371

Strand: Reverse

Name: ydjH [H]

Synonym: DKAM_0615

Alternate gene names: 218883926

Gene position: 583371-582445 (Counterclockwise)

Preceding gene: 218883927

Following gene: 218883925

Centisome position: 42.73

GC content: 44.98

Gene sequence:

>927_bases
ATGGTGAATAAAAGTATTGATGTAGTGACAGTAGGACACGCACTAGTCGACATACGGATAGTTGTGAACGAGTTCCCAAC
GATAGACTTGGAGAGCAAGGTGTTAAATCAGTCATGGGGTTCTGGAGGCTCGGCGGTAAATGTGGCTATAGGTGTGAGAA
GGCTGGGCATGAAGTCCTCCCTGATAGCTAGGGTAGGCTTCGACAGCTTCGGTAGGATAATCGTCGATGAATTACTCAGG
GAGGGAGTCGATATAAGTGGGCTTAGAATAGGTTTCACGCAGACGGGCTTTACTATAGTCGCTATAAATAATAGAGGGGA
AATCATGATGTACGGGTATAAGGGGGCAGCGGAAGAACTAGTGCCAGACGACATCAGTGAATACGCTATATCAAGAGCTA
GATGGATGCATATAGCTAGCCTTAGGCTAGATACCACCATAAGGGCTATTGAGCTAGCTAGGAAACATGGTCTAACAATT
TCATGGGATCCTGGCAGGGTACTTGCTTCACAGGGACTTAGCAACTTAAAGGATGTAGTGGCTAATGTAGACTACATCAT
GCTTAACGAGAAGGAGGCGAGATTAATGACGGGAATAGACGACTATAGAGAAGCTGCTAAGGTGATAGCTAATGAAACCA
GTGCAGTAATATTATTGAAGAGGGGGAGTAAAGGAGTATATGTCCTCTCAAAAGAATACACTGGTGAAATACCTGCTTAT
CTCGTGGAAAACGTTATAGACACCACCGGTGCAGGTGATGCTTTTGCTTCTGGCTTCATAACAGGAATACTACGTGGATA
CATGTTAAGAAAAGCCGTTCAATATGGTAACGCTGTCGCCGCATTGAAGATAAAGAAACTGGGATCGCACCAAGTCCCTC
AGCACGATGAAGTAGTAGAGTTCATATGGGAGAGAGAGCAGGGTTAA

Upstream 100 bases:

>100_bases
CGGTGCCATAAAAGCAATAATGAAGGTCGTACACGAGGAAATGCCGCCCGAAGAAGCTATCAAATACGCTGAGTAAGGGA
GTATAGAAACATGGTGGTTC

Downstream 100 bases:

>100_bases
CACTACTATTGATTCTAAGATACTGGTACCATATTAGTTTTCCTATTAACGTGTTCATCAAGTAATGCTTAATATGGAGA
ACACTTCAATATCTTAGTTC

Product: ATP-dependent 6-phosphofructokinase

Products: ADP; D-ribose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MVNKSIDVVTVGHALVDIRIVVNEFPTIDLESKVLNQSWGSGGSAVNVAIGVRRLGMKSSLIARVGFDSFGRIIVDELLR
EGVDISGLRIGFTQTGFTIVAINNRGEIMMYGYKGAAEELVPDDISEYAISRARWMHIASLRLDTTIRAIELARKHGLTI
SWDPGRVLASQGLSNLKDVVANVDYIMLNEKEARLMTGIDDYREAAKVIANETSAVILLKRGSKGVYVLSKEYTGEIPAY
LVENVIDTTGAGDAFASGFITGILRGYMLRKAVQYGNAVAALKIKKLGSHQVPQHDEVVEFIWEREQG

Sequences:

>Translated_308_residues
MVNKSIDVVTVGHALVDIRIVVNEFPTIDLESKVLNQSWGSGGSAVNVAIGVRRLGMKSSLIARVGFDSFGRIIVDELLR
EGVDISGLRIGFTQTGFTIVAINNRGEIMMYGYKGAAEELVPDDISEYAISRARWMHIASLRLDTTIRAIELARKHGLTI
SWDPGRVLASQGLSNLKDVVANVDYIMLNEKEARLMTGIDDYREAAKVIANETSAVILLKRGSKGVYVLSKEYTGEIPAY
LVENVIDTTGAGDAFASGFITGILRGYMLRKAVQYGNAVAALKIKKLGSHQVPQHDEVVEFIWEREQG
>Mature_308_residues
MVNKSIDVVTVGHALVDIRIVVNEFPTIDLESKVLNQSWGSGGSAVNVAIGVRRLGMKSSLIARVGFDSFGRIIVDELLR
EGVDISGLRIGFTQTGFTIVAINNRGEIMMYGYKGAAEELVPDDISEYAISRARWMHIASLRLDTTIRAIELARKHGLTI
SWDPGRVLASQGLSNLKDVVANVDYIMLNEKEARLMTGIDDYREAAKVIANETSAVILLKRGSKGVYVLSKEYTGEIPAY
LVENVIDTTGAGDAFASGFITGILRGYMLRKAVQYGNAVAALKIKKLGSHQVPQHDEVVEFIWEREQG

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=269, Percent_Identity=29.7397769516729, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI87081971, Length=313, Percent_Identity=28.1150159744409, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082343, Length=301, Percent_Identity=26.9102990033223, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790193, Length=273, Percent_Identity=27.8388278388278, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788417, Length=301, Percent_Identity=22.2591362126246, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17532905, Length=306, Percent_Identity=29.4117647058824, Blast_Score=100, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.15

Molecular weight: Translated: 33729; Mature: 33729

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKSIDVVTVGHALVDIRIVVNEFPTIDLESKVLNQSWGSGGSAVNVAIGVRRLGMKSS
CCCCCEEEEEECHHEEEEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEEEHHHHHCCHHH
LIARVGFDSFGRIIVDELLREGVDISGLRIGFTQTGFTIVAINNRGEIMMYGYKGAAEEL
HHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCEEEEECCCCHHHC
VPDDISEYAISRARWMHIASLRLDTTIRAIELARKHGLTISWDPGRVLASQGLSNLKDVV
CCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHCCCEEEECCCHHHHHCCHHHHHHHH
ANVDYIMLNEKEARLMTGIDDYREAAKVIANETSAVILLKRGSKGVYVLSKEYTGEIPAY
HCCCEEEECCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCHHH
LVENVIDTTGAGDAFASGFITGILRGYMLRKAVQYGNAVAALKIKKLGSHQVPQHDEVVE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHH
FIWEREQG
HHHHCCCC
>Mature Secondary Structure
MVNKSIDVVTVGHALVDIRIVVNEFPTIDLESKVLNQSWGSGGSAVNVAIGVRRLGMKSS
CCCCCEEEEEECHHEEEEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEEEHHHHHCCHHH
LIARVGFDSFGRIIVDELLREGVDISGLRIGFTQTGFTIVAINNRGEIMMYGYKGAAEEL
HHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCEEEEECCCCHHHC
VPDDISEYAISRARWMHIASLRLDTTIRAIELARKHGLTISWDPGRVLASQGLSNLKDVV
CCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHCCCEEEECCCHHHHHCCHHHHHHHH
ANVDYIMLNEKEARLMTGIDDYREAAKVIANETSAVILLKRGSKGVYVLSKEYTGEIPAY
HCCCEEEECCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCHHH
LVENVIDTTGAGDAFASGFITGILRGYMLRKAVQYGNAVAALKIKKLGSHQVPQHDEVVE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHH
FIWEREQG
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-ribose

Specific reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]