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The map label for this gene is thrC [H]

Identifier: 218883925

GI number: 218883925

Start: 581054

End: 582322

Strand: Reverse

Name: thrC [H]

Synonym: DKAM_0614

Alternate gene names: 218883925

Gene position: 582322-581054 (Counterclockwise)

Preceding gene: 218883926

Following gene: 218883924

Centisome position: 42.65

GC content: 47.04

Gene sequence:

>1269_bases
TTGTATGTAAGAGAATTGAAGTGTAGTAGGTGTGGTAGAAGACTACTTCTAAGCGAGAAACCATTGACATGCCCCAGCAA
GGATCTGGGTAGGCTAGATATAGTGTATGACTATGAAGCGATAGCTGAGAGCATTAATAGAGATATTCTCTCACAAAGAT
CATTCAACATGTGGAGATACATGGAATTCCTCCCAGTGCCAAGCAGAGACTATATTGTCTCACTTGGTGAAGGGGGTACC
CCCCTACTAAAGGCGAGGAGACTTGGAGAGAAGTTGGGCCTGAGAAACCTGTATCTTAAGGATGAAACAAGGAACCCAAC
TGGGAGCTTTAAGGATAGAGCAATGAGCGTGTCTGTGTCCATGGCCGTGTACTTCGGCTTCAAGAAGGCAGTGATCGCTA
GCAGTGGTAATGCAGCCGCATCTCTAGCAGCCTATGGGGCTAAAGCCGGTATAGAAGTCTATGCATTTGTCCCTGATTTC
GCTGGCTATGGTAAAATAGCCCAATTACTCTATTATGGAGCCAAAGTATTTAAGGTTAGATGGAGTGAAGCAGAGGATCC
CACGGTTAAAATGATGCGTATCCTCTATGAGGAACACGGCTTCTACCCGAGTCCAAGCTTCGGCGTCTTCAACCCATACC
AGGTGGAGGGACCTAAGACCATCTCTATGGAAATAGTAGAGCAATTGAAATGGATAGTTCCGGATCAAGTTTTTGTACCA
ACCGGTGCAGCCAGCCTATTAACCGGGGTCTTCAACGGGTTCAGGGACTTCAATATGGTTGGATGGATAAACCGGTATCC
TAAGCTAGTAGCTGTACAGCCCGAGGGAAATCACCCCTTTGTAAGGGCTTGGAGAGAAAGGGCTGATCCGATGAATATAC
GTCCCTGGGAGAAGCCGCCGGATACAATAGCTACCGGGCTAGAAGACACTTATCCATGGGATGGCGATGCCGGATTAAAG
GCCTTATACACCACCAATGGTTACGGTGTAGTTGTAAGCGATAAGGAAATACTGGATTCAATGAAGATGCTGGCTAGTCT
TGAAGGCGTATTCGCTGAGCCAAGTGGTGCAGCCGGTTTAGCCGGCCTAATAAAGGCTATTGAGGAGAAACAGGTGGATA
GGGATGAAGTAATCGTGGTACTAGTCACAGGACACGGCCTAAAGGATCCTGATATAATTAGGAAAACAGCCGGGGAACCC
CCATTAATAAACCCAAATGTTGAGGAATTCAGGAAGACTGCCCGCGAATTCTATGGTGTTTTAGCCTAG

Upstream 100 bases:

>100_bases
CTGGTACCATATTAGTTTTCCTATTAACGTGTTCATCAAGTAATGCTTAATATGGAGAACACTTCAATATCTTAGTTCAA
GAACCCGGGGTGTAAAGATA

Downstream 100 bases:

>100_bases
TCTTAATCAAATAAGGTTTTTCACTCCCTATCCTAAATATTATTGCCTTGAGTGTGTCATCCATGATGATTATTCATACA
GGAGACCTACACTTAGGGTG

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MYVRELKCSRCGRRLLLSEKPLTCPSKDLGRLDIVYDYEAIAESINRDILSQRSFNMWRYMEFLPVPSRDYIVSLGEGGT
PLLKARRLGEKLGLRNLYLKDETRNPTGSFKDRAMSVSVSMAVYFGFKKAVIASSGNAAASLAAYGAKAGIEVYAFVPDF
AGYGKIAQLLYYGAKVFKVRWSEAEDPTVKMMRILYEEHGFYPSPSFGVFNPYQVEGPKTISMEIVEQLKWIVPDQVFVP
TGAASLLTGVFNGFRDFNMVGWINRYPKLVAVQPEGNHPFVRAWRERADPMNIRPWEKPPDTIATGLEDTYPWDGDAGLK
ALYTTNGYGVVVSDKEILDSMKMLASLEGVFAEPSGAAGLAGLIKAIEEKQVDRDEVIVVLVTGHGLKDPDIIRKTAGEP
PLINPNVEEFRKTAREFYGVLA

Sequences:

>Translated_422_residues
MYVRELKCSRCGRRLLLSEKPLTCPSKDLGRLDIVYDYEAIAESINRDILSQRSFNMWRYMEFLPVPSRDYIVSLGEGGT
PLLKARRLGEKLGLRNLYLKDETRNPTGSFKDRAMSVSVSMAVYFGFKKAVIASSGNAAASLAAYGAKAGIEVYAFVPDF
AGYGKIAQLLYYGAKVFKVRWSEAEDPTVKMMRILYEEHGFYPSPSFGVFNPYQVEGPKTISMEIVEQLKWIVPDQVFVP
TGAASLLTGVFNGFRDFNMVGWINRYPKLVAVQPEGNHPFVRAWRERADPMNIRPWEKPPDTIATGLEDTYPWDGDAGLK
ALYTTNGYGVVVSDKEILDSMKMLASLEGVFAEPSGAAGLAGLIKAIEEKQVDRDEVIVVLVTGHGLKDPDIIRKTAGEP
PLINPNVEEFRKTAREFYGVLA
>Mature_422_residues
MYVRELKCSRCGRRLLLSEKPLTCPSKDLGRLDIVYDYEAIAESINRDILSQRSFNMWRYMEFLPVPSRDYIVSLGEGGT
PLLKARRLGEKLGLRNLYLKDETRNPTGSFKDRAMSVSVSMAVYFGFKKAVIASSGNAAASLAAYGAKAGIEVYAFVPDF
AGYGKIAQLLYYGAKVFKVRWSEAEDPTVKMMRILYEEHGFYPSPSFGVFNPYQVEGPKTISMEIVEQLKWIVPDQVFVP
TGAASLLTGVFNGFRDFNMVGWINRYPKLVAVQPEGNHPFVRAWRERADPMNIRPWEKPPDTIATGLEDTYPWDGDAGLK
ALYTTNGYGVVVSDKEILDSMKMLASLEGVFAEPSGAAGLAGLIKAIEEKQVDRDEVIVVLVTGHGLKDPDIIRKTAGEP
PLINPNVEEFRKTAREFYGVLA

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322631, Length=291, Percent_Identity=28.1786941580756, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 47059; Mature: 47059

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00037 MYB_1 ; PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVRELKCSRCGRRLLLSEKPLTCPSKDLGRLDIVYDYEAIAESINRDILSQRSFNMWRY
CCCHHHHHHHHCCEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHH
MEFLPVPSRDYIVSLGEGGTPLLKARRLGEKLGLRNLYLKDETRNPTGSFKDRAMSVSVS
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHEEEEEEE
MAVYFGFKKAVIASSGNAAASLAAYGAKAGIEVYAFVPDFAGYGKIAQLLYYGAKVFKVR
EEEHHHHHHHEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEE
WSEAEDPTVKMMRILYEEHGFYPSPSFGVFNPYQVEGPKTISMEIVEQLKWIVPDQVFVP
ECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEHHHHHHHHHHHCCCCEEEC
TGAASLLTGVFNGFRDFNMVGWINRYPKLVAVQPEGNHPFVRAWRERADPMNIRPWEKPP
CCHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCC
DTIATGLEDTYPWDGDAGLKALYTTNGYGVVVSDKEILDSMKMLASLEGVFAEPSGAAGL
HHHHCCCCCCCCCCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHH
AGLIKAIEEKQVDRDEVIVVLVTGHGLKDPDIIRKTAGEPPLINPNVEEFRKTAREFYGV
HHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
LA
CC
>Mature Secondary Structure
MYVRELKCSRCGRRLLLSEKPLTCPSKDLGRLDIVYDYEAIAESINRDILSQRSFNMWRY
CCCHHHHHHHHCCEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHH
MEFLPVPSRDYIVSLGEGGTPLLKARRLGEKLGLRNLYLKDETRNPTGSFKDRAMSVSVS
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHEEEEEEE
MAVYFGFKKAVIASSGNAAASLAAYGAKAGIEVYAFVPDFAGYGKIAQLLYYGAKVFKVR
EEEHHHHHHHEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEE
WSEAEDPTVKMMRILYEEHGFYPSPSFGVFNPYQVEGPKTISMEIVEQLKWIVPDQVFVP
ECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEHHHHHHHHHHHCCCCEEEC
TGAASLLTGVFNGFRDFNMVGWINRYPKLVAVQPEGNHPFVRAWRERADPMNIRPWEKPP
CCHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCC
DTIATGLEDTYPWDGDAGLKALYTTNGYGVVVSDKEILDSMKMLASLEGVFAEPSGAAGL
HHHHCCCCCCCCCCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHH
AGLIKAIEEKQVDRDEVIVVLVTGHGLKDPDIIRKTAGEPPLINPNVEEFRKTAREFYGV
HHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
LA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]