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The map label for this gene is 218883894

Identifier: 218883894

GI number: 218883894

Start: 544030

End: 545583

Strand: Reverse

Name: 218883894

Synonym: DKAM_0583

Alternate gene names: NA

Gene position: 545583-544030 (Counterclockwise)

Preceding gene: 218883895

Following gene: 218883893

Centisome position: 39.96

GC content: 44.92

Gene sequence:

>1554_bases
GTGGGTCCAGTGAGTAGGGAAAGAGAAACATGGGCAACCAGGTTCGGATTGATATTATCAATGGCTGGGAACGCTATTGG
ACTAGGTAATTTCTGGCGATTCCCCAGGCTACTCGCTGCAAACGGTGGCGGCGCATTCATGATACCATACTTCATAGCAT
TGCTGTTACTGGGTATACCATTGATGTGGGTTGAATGGAGTACAGGGAGATATGGCGGTAAATACGGGCATGGAACGCTC
GGTCCAATGTTCTACCTGATGGCCAGGGAGTCGGTTAAGCCTAGGACAGCATTAATATTCGGCATTATAGGGGGCATGTT
AGCCTTTGCTGTGACCACATTGCTAAACTCTTATTACATCCATGTGATAGGTTGGACAGCAGCATACGTTATATATAGTG
CAGCAGGGTCATACTATGGAGCAAACACTGTAGAATTCTTCAATAACCATATAGCTAACACCAGCATGGTGCTTGCCACA
TGGAGTATACCCATGATACTGCTCTTTATAGCTGCCTATAGGGGGGTGGCCAAAGGCATTGAGTTATTTAACAAGATCAT
GATGCCGTTGCTCTATGTCTTTGCCATTATTCTAGCAATAAGATCGATAACAACTGGAGCACCGGTGAGGCCTGACTGGA
GCTCCTGGGCCGGGCTCCGGTACAGCTGGAATCCGGACTTTGAAACATTGAGAAGTAACTTCTGGGTTATCTCGCTAGCT
GCGGCGGGCCAGATATTCTTTACATTAAGCCTTGGAATGGGTATAATACATAATTATGCGTCATACGTTAAGAAGGATGA
TGATATAGCACTAGCAGGCTTAACAACAACATCCCTCAACGAGGTGGCAGAGGTAATACTAGGCGGCACAATAGCGGTAC
CATTAGCATACGCATATCTAGGTCCAGACGTGGTTAAACAAGGCTCGCTGGGATTAGCTTTCATGGCACTACCAAATGTC
TTCACGGCCCTAGGTGATGTAGGCAGGGTCTTCGGCATGTTATGGTTCCTCCTACTGTTCTTCGCAGGGTGGACATCCGC
TATAGCAATGTATAATTATCTAGTGGCATTACTAGAGGAGGACTTAGGCATCAATAGGAGGCTTGGGTCACTTATAGTAT
TTATACTGTACTTCTTGCTGGGATTACCGGTGGCGCTAGACTCTTCTCTTACATACTTCGGTGAACTAGATAACTGGGTT
GGCTCATACCTGCTGGTAGTTCTTGGGTTATTCGATGTAATAGTGGGAGTCTACCTGTTTAAACCAGATAACTTATGGAA
GGAGCTCCATACTGGTGCATTGATACGTGTACCATCATTATTCAAGTATATATTAATGACGCTGACCCCGATATACATAT
TAATACTATTGGTTGGAACAACAATAGATTATTATAACCAAGGGGTCTTCGCGCAAGCAGATCCCTTGATAGTGCGCGCC
AGGATAGCTATAATACTTGTATTGATCATCGGAGCGATTGAAACATACTATGGAATCAAGAAGAAATATGGTAAGGAATT
GGCTGAAAACAGGAAGATCATAGTGGTCGAGTAG

Upstream 100 bases:

>100_bases
TATTATTTTTAAAGTGAAACATTGGTGGGTTAGAAATATTTGTTCTATAATTCAGTTAATATTTTTATACTTAATACTAT
AAAAATGAGTATTATGTTAG

Downstream 100 bases:

>100_bases
AGGTGGAAGACATGGAGCAGTTGTGGATAGTCTTCATGCTGGGATCATGGCTATTCATACTGGGCTTGTCGGCCTGGTGT
ATCTGGAAGAATCTTAAGGC

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MGPVSRERETWATRFGLILSMAGNAIGLGNFWRFPRLLAANGGGAFMIPYFIALLLLGIPLMWVEWSTGRYGGKYGHGTL
GPMFYLMARESVKPRTALIFGIIGGMLAFAVTTLLNSYYIHVIGWTAAYVIYSAAGSYYGANTVEFFNNHIANTSMVLAT
WSIPMILLFIAAYRGVAKGIELFNKIMMPLLYVFAIILAIRSITTGAPVRPDWSSWAGLRYSWNPDFETLRSNFWVISLA
AAGQIFFTLSLGMGIIHNYASYVKKDDDIALAGLTTTSLNEVAEVILGGTIAVPLAYAYLGPDVVKQGSLGLAFMALPNV
FTALGDVGRVFGMLWFLLLFFAGWTSAIAMYNYLVALLEEDLGINRRLGSLIVFILYFLLGLPVALDSSLTYFGELDNWV
GSYLLVVLGLFDVIVGVYLFKPDNLWKELHTGALIRVPSLFKYILMTLTPIYILILLVGTTIDYYNQGVFAQADPLIVRA
RIAIILVLIIGAIETYYGIKKKYGKELAENRKIIVVE

Sequences:

>Translated_517_residues
MGPVSRERETWATRFGLILSMAGNAIGLGNFWRFPRLLAANGGGAFMIPYFIALLLLGIPLMWVEWSTGRYGGKYGHGTL
GPMFYLMARESVKPRTALIFGIIGGMLAFAVTTLLNSYYIHVIGWTAAYVIYSAAGSYYGANTVEFFNNHIANTSMVLAT
WSIPMILLFIAAYRGVAKGIELFNKIMMPLLYVFAIILAIRSITTGAPVRPDWSSWAGLRYSWNPDFETLRSNFWVISLA
AAGQIFFTLSLGMGIIHNYASYVKKDDDIALAGLTTTSLNEVAEVILGGTIAVPLAYAYLGPDVVKQGSLGLAFMALPNV
FTALGDVGRVFGMLWFLLLFFAGWTSAIAMYNYLVALLEEDLGINRRLGSLIVFILYFLLGLPVALDSSLTYFGELDNWV
GSYLLVVLGLFDVIVGVYLFKPDNLWKELHTGALIRVPSLFKYILMTLTPIYILILLVGTTIDYYNQGVFAQADPLIVRA
RIAIILVLIIGAIETYYGIKKKYGKELAENRKIIVVE
>Mature_516_residues
GPVSRERETWATRFGLILSMAGNAIGLGNFWRFPRLLAANGGGAFMIPYFIALLLLGIPLMWVEWSTGRYGGKYGHGTLG
PMFYLMARESVKPRTALIFGIIGGMLAFAVTTLLNSYYIHVIGWTAAYVIYSAAGSYYGANTVEFFNNHIANTSMVLATW
SIPMILLFIAAYRGVAKGIELFNKIMMPLLYVFAIILAIRSITTGAPVRPDWSSWAGLRYSWNPDFETLRSNFWVISLAA
AGQIFFTLSLGMGIIHNYASYVKKDDDIALAGLTTTSLNEVAEVILGGTIAVPLAYAYLGPDVVKQGSLGLAFMALPNVF
TALGDVGRVFGMLWFLLLFFAGWTSAIAMYNYLVALLEEDLGINRRLGSLIVFILYFLLGLPVALDSSLTYFGELDNWVG
SYLLVVLGLFDVIVGVYLFKPDNLWKELHTGALIRVPSLFKYILMTLTPIYILILLVGTTIDYYNQGVFAQADPLIVRAR
IAIILVLIIGAIETYYGIKKKYGKELAENRKIIVVE

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=499, Percent_Identity=28.0561122244489, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI7657587, Length=520, Percent_Identity=25.3846153846154, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI21361581, Length=514, Percent_Identity=25.2918287937743, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI67782317, Length=517, Percent_Identity=25.531914893617, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI67782313, Length=517, Percent_Identity=25.531914893617, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI67782315, Length=517, Percent_Identity=25.531914893617, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI171184408, Length=500, Percent_Identity=25.2, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI171184406, Length=500, Percent_Identity=25.2, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI171184404, Length=500, Percent_Identity=25.2, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI289191377, Length=507, Percent_Identity=24.8520710059172, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI289191351, Length=507, Percent_Identity=24.8520710059172, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4557046, Length=507, Percent_Identity=24.8520710059172, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4507043, Length=401, Percent_Identity=24.9376558603491, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI4507041, Length=507, Percent_Identity=24.2603550295858, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI33354281, Length=313, Percent_Identity=27.1565495207668, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI134304856, Length=503, Percent_Identity=23.6580516898608, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI197276623, Length=519, Percent_Identity=23.8921001926782, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI54607094, Length=519, Percent_Identity=23.8921001926782, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI194018524, Length=306, Percent_Identity=30.3921568627451, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI58219014, Length=310, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI197276625, Length=153, Percent_Identity=35.2941176470588, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI5032097, Length=367, Percent_Identity=24.5231607629428, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI11181770, Length=312, Percent_Identity=25.3205128205128, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI51468073, Length=517, Percent_Identity=23.21083172147, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI21361693, Length=126, Percent_Identity=35.7142857142857, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI218563756, Length=310, Percent_Identity=24.8387096774194, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI92859670, Length=74, Percent_Identity=45.945945945946, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI6005715, Length=79, Percent_Identity=46.8354430379747, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555248, Length=523, Percent_Identity=24.4741873804971, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25146584, Length=504, Percent_Identity=25.5952380952381, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71995588, Length=498, Percent_Identity=24.6987951807229, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI133952791, Length=545, Percent_Identity=25.6880733944954, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17554804, Length=411, Percent_Identity=27.2506082725061, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17542050, Length=123, Percent_Identity=38.2113821138211, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17535731, Length=134, Percent_Identity=34.3283582089552, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI212642127, Length=463, Percent_Identity=24.622030237581, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136952, Length=532, Percent_Identity=23.3082706766917, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281364394, Length=532, Percent_Identity=23.3082706766917, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28574704, Length=532, Percent_Identity=23.3082706766917, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI17136950, Length=532, Percent_Identity=23.3082706766917, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28574702, Length=532, Percent_Identity=23.3082706766917, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24762620, Length=516, Percent_Identity=25, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19921936, Length=507, Percent_Identity=23.8658777120316, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45550877, Length=491, Percent_Identity=24.847250509165, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281365034, Length=519, Percent_Identity=24.0847784200385, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI45551088, Length=389, Percent_Identity=25.9640102827763, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19921352, Length=509, Percent_Identity=24.3614931237721, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24584353, Length=509, Percent_Identity=24.3614931237721, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24652942, Length=389, Percent_Identity=25.9640102827763, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI45551183, Length=449, Percent_Identity=25.3897550111359, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281364136, Length=496, Percent_Identity=26.8145161290323, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24582567, Length=351, Percent_Identity=24.5014245014245, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24639516, Length=326, Percent_Identity=26.6871165644172, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24639514, Length=535, Percent_Identity=23.7383177570093, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221329674, Length=535, Percent_Identity=23.7383177570093, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24655079, Length=543, Percent_Identity=23.0202578268877, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24654186, Length=84, Percent_Identity=45.2380952380952, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363702, Length=72, Percent_Identity=41.6666666666667, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363700, Length=72, Percent_Identity=41.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24661428, Length=74, Percent_Identity=35.1351351351351, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 57158; Mature: 57027

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVSRERETWATRFGLILSMAGNAIGLGNFWRFPRLLAANGGGAFMIPYFIALLLLGIP
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHEEECCCCEEHHHHHHHHHHHCCC
LMWVEWSTGRYGGKYGHGTLGPMFYLMARESVKPRTALIFGIIGGMLAFAVTTLLNSYYI
CEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HVIGWTAAYVIYSAAGSYYGANTVEFFNNHIANTSMVLATWSIPMILLFIAAYRGVAKGI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
ELFNKIMMPLLYVFAIILAIRSITTGAPVRPDWSSWAGLRYSWNPDFETLRSNFWVISLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCHHHHHCCCEEEEEE
AAGQIFFTLSLGMGIIHNYASYVKKDDDIALAGLTTTSLNEVAEVILGGTIAVPLAYAYL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHH
GPDVVKQGSLGLAFMALPNVFTALGDVGRVFGMLWFLLLFFAGWTSAIAMYNYLVALLEE
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGINRRLGSLIVFILYFLLGLPVALDSSLTYFGELDNWVGSYLLVVLGLFDVIVGVYLF
HCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPDNLWKELHTGALIRVPSLFKYILMTLTPIYILILLVGTTIDYYNQGVFAQADPLIVRA
CCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RIAIILVLIIGAIETYYGIKKKYGKELAENRKIIVVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
GPVSRERETWATRFGLILSMAGNAIGLGNFWRFPRLLAANGGGAFMIPYFIALLLLGIP
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHEEECCCCEEHHHHHHHHHHHCCC
LMWVEWSTGRYGGKYGHGTLGPMFYLMARESVKPRTALIFGIIGGMLAFAVTTLLNSYYI
CEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HVIGWTAAYVIYSAAGSYYGANTVEFFNNHIANTSMVLATWSIPMILLFIAAYRGVAKGI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
ELFNKIMMPLLYVFAIILAIRSITTGAPVRPDWSSWAGLRYSWNPDFETLRSNFWVISLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCHHHHHCCCEEEEEE
AAGQIFFTLSLGMGIIHNYASYVKKDDDIALAGLTTTSLNEVAEVILGGTIAVPLAYAYL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHH
GPDVVKQGSLGLAFMALPNVFTALGDVGRVFGMLWFLLLFFAGWTSAIAMYNYLVALLEE
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGINRRLGSLIVFILYFLLGLPVALDSSLTYFGELDNWVGSYLLVVLGLFDVIVGVYLF
HCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPDNLWKELHTGALIRVPSLFKYILMTLTPIYILILLVGTTIDYYNQGVFAQADPLIVRA
CCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RIAIILVLIIGAIETYYGIKKKYGKELAENRKIIVVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]