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The map label for this gene is thiL [H]

Identifier: 218883885

GI number: 218883885

Start: 537210

End: 538232

Strand: Direct

Name: thiL [H]

Synonym: DKAM_0574

Alternate gene names: 218883885

Gene position: 537210-538232 (Clockwise)

Preceding gene: 218883884

Following gene: 218883886

Centisome position: 39.35

GC content: 47.21

Gene sequence:

>1023_bases
GTGGCTTCATTGAGGGGATCCCTTGGGGAAATGGGTGAGGAAGCTGTAATAAATCTTATAGCTGATAAACTGATCAGCAA
GCCTGAATCGGGCGAGAGTCTTACGTATCCCGATGATGCTAGAGATTTACTGCCAAAAGGCCCTAGGTTAATATATTCCA
TGGATGCTTATAGAATAAAATCGCTTATGCTTCCATGGAGGACCTGGAGCGATATCGGGTGGATGGCTTTAACCGGTGCC
CTTAGCGATGTAGTGGTTAAAGGCGGAGTGCCTAGTGTAGCAATGATTGGGTTAGGACTTAGCAGTGAAACAGATATCCT
GGATTTAGAGGAGCTGGTCAAGGGGCTCCGTGAAGCGAGTAACTACTATGATGTGAGGATTACAGGGGGAGATACAAATG
AAAGCCTTGATCCATGGATAGCTGTCTCAGTAATGGGGTTTACAACCTGTAAACGTCCCCCAAGTAGGCGTGGAGCCAGG
CCAGGCGACATCGTTATCGCCACGGGATCTTATGGCTCGATGGGTTTTGTAGCGCTCCACGGTGTCGTGGAGGCTAGTGG
AATAAGCTGGGTCGTTGATAACACTAAGAGGGTGTATTTGAAGCTCGAAGTAGCCAACGTGATCATGTCTACTTATAGAT
TCATTCATGCTTCAATGGATGTAAGTGATGGACTTGGATATACCTTGGAACAACTCTCAGAGCTCAGCGGGTATGGTATA
CTCCTTGAGAATCTCCCGGTACACCCAGCAGGACTTAGAGAGTATTGCAAGAACAGTATTGAATGCATGTGGAGGCATGT
ACTAGTTGGAGGAGAGGAGTATGGTGCCGTGCTAATTGTCGCTGGAGAGTACCTGGATAAAGTGGCTGAGGAACTAGATT
ACTATGAGATACCATATAGTATCATAGGGAGGGTGGGAAACATATCCCCGGGAATATATATTAATGGAGCCAGGATCACT
GTGGAAAGATGGGATCAATTCAGGGGGTGGGGGAAACGTTTTCCAATGGGTGATGCCCGGTAA

Upstream 100 bases:

>100_bases
GATGAAACCAGCTTATATAAACCTATATGAGACCTAAACCCCTTTAACATGGAGCTCTAACTAAATATTTCATGAAGAGA
GATAAAAACATGTAGTCAAG

Downstream 100 bases:

>100_bases
GCTAGCTCAATCACCTATGCCTAGATTAAGTGATATCCCTGCACTGACACGATACTTTACCGGGGTAGTGGCATTAATGG
ATCAGCATGATGCACCGTTA

Product: AIR synthase-like protein domain-containing protein

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MASLRGSLGEMGEEAVINLIADKLISKPESGESLTYPDDARDLLPKGPRLIYSMDAYRIKSLMLPWRTWSDIGWMALTGA
LSDVVVKGGVPSVAMIGLGLSSETDILDLEELVKGLREASNYYDVRITGGDTNESLDPWIAVSVMGFTTCKRPPSRRGAR
PGDIVIATGSYGSMGFVALHGVVEASGISWVVDNTKRVYLKLEVANVIMSTYRFIHASMDVSDGLGYTLEQLSELSGYGI
LLENLPVHPAGLREYCKNSIECMWRHVLVGGEEYGAVLIVAGEYLDKVAEELDYYEIPYSIIGRVGNISPGIYINGARIT
VERWDQFRGWGKRFPMGDAR

Sequences:

>Translated_340_residues
MASLRGSLGEMGEEAVINLIADKLISKPESGESLTYPDDARDLLPKGPRLIYSMDAYRIKSLMLPWRTWSDIGWMALTGA
LSDVVVKGGVPSVAMIGLGLSSETDILDLEELVKGLREASNYYDVRITGGDTNESLDPWIAVSVMGFTTCKRPPSRRGAR
PGDIVIATGSYGSMGFVALHGVVEASGISWVVDNTKRVYLKLEVANVIMSTYRFIHASMDVSDGLGYTLEQLSELSGYGI
LLENLPVHPAGLREYCKNSIECMWRHVLVGGEEYGAVLIVAGEYLDKVAEELDYYEIPYSIIGRVGNISPGIYINGARIT
VERWDQFRGWGKRFPMGDAR
>Mature_339_residues
ASLRGSLGEMGEEAVINLIADKLISKPESGESLTYPDDARDLLPKGPRLIYSMDAYRIKSLMLPWRTWSDIGWMALTGAL
SDVVVKGGVPSVAMIGLGLSSETDILDLEELVKGLREASNYYDVRITGGDTNESLDPWIAVSVMGFTTCKRPPSRRGARP
GDIVIATGSYGSMGFVALHGVVEASGISWVVDNTKRVYLKLEVANVIMSTYRFIHASMDVSDGLGYTLEQLSELSGYGIL
LENLPVHPAGLREYCKNSIECMWRHVLVGGEEYGAVLIVAGEYLDKVAEELDYYEIPYSIIGRVGNISPGIYINGARITV
ERWDQFRGWGKRFPMGDAR

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=270, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 37345; Mature: 37214

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLRGSLGEMGEEAVINLIADKLISKPESGESLTYPDDARDLLPKGPRLIYSMDAYRIK
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCEEEEECCHHHHH
SLMLPWRTWSDIGWMALTGALSDVVVKGGVPSVAMIGLGLSSETDILDLEELVKGLREAS
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC
NYYDVRITGGDTNESLDPWIAVSVMGFTTCKRPPSRRGARPGDIVIATGSYGSMGFVALH
CEEEEEEECCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHH
GVVEASGISWVVDNTKRVYLKLEVANVIMSTYRFIHASMDVSDGLGYTLEQLSELSGYGI
HHHHCCCCEEEEECCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEE
LLENLPVHPAGLREYCKNSIECMWRHVLVGGEEYGAVLIVAGEYLDKVAEELDYYEIPYS
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHCCCEECCHH
IIGRVGNISPGIYINGARITVERWDQFRGWGKRFPMGDAR
HHCCCCCCCCCEEEECCEEEHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ASLRGSLGEMGEEAVINLIADKLISKPESGESLTYPDDARDLLPKGPRLIYSMDAYRIK
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCEEEEECCHHHHH
SLMLPWRTWSDIGWMALTGALSDVVVKGGVPSVAMIGLGLSSETDILDLEELVKGLREAS
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC
NYYDVRITGGDTNESLDPWIAVSVMGFTTCKRPPSRRGARPGDIVIATGSYGSMGFVALH
CEEEEEEECCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHH
GVVEASGISWVVDNTKRVYLKLEVANVIMSTYRFIHASMDVSDGLGYTLEQLSELSGYGI
HHHHCCCCEEEEECCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEE
LLENLPVHPAGLREYCKNSIECMWRHVLVGGEEYGAVLIVAGEYLDKVAEELDYYEIPYS
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHCCCEECCHH
IIGRVGNISPGIYINGARITVERWDQFRGWGKRFPMGDAR
HHCCCCCCCCCEEEECCEEEHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]