Click here to switch to the map view.

The map label for this gene is ybiK [C]

Identifier: 218883855

GI number: 218883855

Start: 509745

End: 510806

Strand: Reverse

Name: ybiK [C]

Synonym: DKAM_0544

Alternate gene names: 218883855

Gene position: 510806-509745 (Counterclockwise)

Preceding gene: 218883857

Following gene: 218883854

Centisome position: 37.42

GC content: 49.62

Gene sequence:

>1062_bases
ATGGTAATACAGTGGTTCACTCATAGCTGTCTTAGAGTTTTAAACTATAGTAGCAATCTATACTATGATGGTGAAAACAT
GGTTAAGGCCCTTATTCTCCATGGTGGAGCTGGAAGCTGGAGAGATGAATCTATTAGAGTTAAAGCCGAGAAGGTTATCG
AGGAGTGTACCAGGCGTGCTTGGCGGATACTCGGGGAATCCAATAACGCCCTCAACACAGTAGTTGAGGCCGTGAGATGC
ATGGAGGACTCGGGAATCCTTAACGCTGGCTACGGCTCTACCCTTGATCTACTCGGTGGGAGAAGCCTTGATGCCGGTTT
AATGACTTCAACAGGCCTCCTCGGTGCTGTCGCAGCTGTGAAGGCTACACGTAACCCAATCCTACTGGCTAGAATAGTCG
CGGAGGAGACACCCCATGTACTACTGGCTGGCGGGAGCGCTGATGAATTAGCCATGTTAAAGGGTTTACCACCACTGCCG
CCACCGCCTCCACACGTTGTTGAGAGATATGTTCAGGCAGGTAGGAAGCTACTGGGTGGAGACTTGAAGCAGGACTACTA
TATGAAGATACGTGAATTCGTGTATAGGCATGGTAGCTCATACTACACTATGCTCAAGGAACTTGTAAACGTCTACGATA
CAGTGGGGGCTGTGGCGCTGGATGAAAAAGGAGTCTTGGCAGCAGCAACAAGTACTGGGGGAGTCATATTGAAGCTCCCC
GGCAGAGTAGGGGACACACCAATACCTGGGGCCGGGTTTTACGCGTCGAGCACTACAGCCTGCAGTGCTACAGGGATCGG
TGAATACATTATAAGGGTGATGCCGTGTCTGAGGCTAGACATGGAGGTCTCAGGCGGCATGGATCTCGAGGAGGCGCTCG
GAAAGATAATGTATTATACTGAGAAAACCGTTGGGCAGGATGCACTCGGATTCATCGGTGTAAGCAGGGATGGCAGGATA
TTCTATGCGTACAATACTGATGGCATGCTAATAGGGTACATGAGGGATGATGGGGAAATATATGTTGCATCACAGCATCC
AGTTAAGGTAAAGGTAGTTTAG

Upstream 100 bases:

>100_bases
TTCCCATGGCTACACTGCTCATTCGCTCTCACCACGAATCTGGTATCTATCTTTATCTGGAAGCTAGTTAAATACATTAT
TAATATAAGGATCCTAATCC

Downstream 100 bases:

>100_bases
GGATGAGCTGTATCGAGACAATAGTCATAGATGTAGATGGAACACTGATACCAAGCCTAGTAGACTTCGATAAACTCAGG
AGGAGAATAAGGGAAGAACT

Product: Asparaginase

Products: NA

Alternate protein names: L-asparagine amidohydrolase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MVIQWFTHSCLRVLNYSSNLYYDGENMVKALILHGGAGSWRDESIRVKAEKVIEECTRRAWRILGESNNALNTVVEAVRC
MEDSGILNAGYGSTLDLLGGRSLDAGLMTSTGLLGAVAAVKATRNPILLARIVAEETPHVLLAGGSADELAMLKGLPPLP
PPPPHVVERYVQAGRKLLGGDLKQDYYMKIREFVYRHGSSYYTMLKELVNVYDTVGAVALDEKGVLAAATSTGGVILKLP
GRVGDTPIPGAGFYASSTTACSATGIGEYIIRVMPCLRLDMEVSGGMDLEEALGKIMYYTEKTVGQDALGFIGVSRDGRI
FYAYNTDGMLIGYMRDDGEIYVASQHPVKVKVV

Sequences:

>Translated_353_residues
MVIQWFTHSCLRVLNYSSNLYYDGENMVKALILHGGAGSWRDESIRVKAEKVIEECTRRAWRILGESNNALNTVVEAVRC
MEDSGILNAGYGSTLDLLGGRSLDAGLMTSTGLLGAVAAVKATRNPILLARIVAEETPHVLLAGGSADELAMLKGLPPLP
PPPPHVVERYVQAGRKLLGGDLKQDYYMKIREFVYRHGSSYYTMLKELVNVYDTVGAVALDEKGVLAAATSTGGVILKLP
GRVGDTPIPGAGFYASSTTACSATGIGEYIIRVMPCLRLDMEVSGGMDLEEALGKIMYYTEKTVGQDALGFIGVSRDGRI
FYAYNTDGMLIGYMRDDGEIYVASQHPVKVKVV
>Mature_353_residues
MVIQWFTHSCLRVLNYSSNLYYDGENMVKALILHGGAGSWRDESIRVKAEKVIEECTRRAWRILGESNNALNTVVEAVRC
MEDSGILNAGYGSTLDLLGGRSLDAGLMTSTGLLGAVAAVKATRNPILLARIVAEETPHVLLAGGSADELAMLKGLPPLP
PPPPHVVERYVQAGRKLLGGDLKQDYYMKIREFVYRHGSSYYTMLKELVNVYDTVGAVALDEKGVLAAATSTGGVILKLP
GRVGDTPIPGAGFYASSTTACSATGIGEYIIRVMPCLRLDMEVSGGMDLEEALGKIMYYTEKTVGQDALGFIGVSRDGRI
FYAYNTDGMLIGYMRDDGEIYVASQHPVKVKVV

Specific function: Unknown

COG id: COG1446

COG function: function code E; Asparaginase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ntn-hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI145275202, Length=308, Percent_Identity=32.7922077922078, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI145275200, Length=308, Percent_Identity=32.7922077922078, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI98991769, Length=356, Percent_Identity=28.6516853932584, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI285002251, Length=269, Percent_Identity=29.368029739777, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1787050, Length=311, Percent_Identity=35.3697749196142, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17569239, Length=265, Percent_Identity=27.1698113207547, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18921183, Length=320, Percent_Identity=33.4375, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357893, Length=360, Percent_Identity=28.6111111111111, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24652135, Length=236, Percent_Identity=33.8983050847458, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI221330102, Length=236, Percent_Identity=33.8983050847458, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24655553, Length=317, Percent_Identity=29.6529968454259, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000246 [H]

Pfam domain/function: PF01112 Asparaginase_2 [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 38199; Mature: 38199

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIQWFTHSCLRVLNYSSNLYYDGENMVKALILHGGAGSWRDESIRVKAEKVIEECTRRA
CEEEHHHHHHHHHHCCCCCEEECCHHHEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHH
WRILGESNNALNTVVEAVRCMEDSGILNAGYGSTLDLLGGRSLDAGLMTSTGLLGAVAAV
HHHHCCCCCHHHHHHHHHHHHHCCCCEECCCCCEEHHCCCCCCCCCHHHHHHHHHHHHHH
KATRNPILLARIVAEETPHVLLAGGSADELAMLKGLPPLPPPPPHVVERYVQAGRKLLGG
HHCCCCEEEEEEHHCCCCEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
DLKQDYYMKIREFVYRHGSSYYTMLKELVNVYDTVGAVALDEKGVLAAATSTGGVILKLP
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCEEEECC
GRVGDTPIPGAGFYASSTTACSATGIGEYIIRVMPCLRLDMEVSGGMDLEEALGKIMYYT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHEEHH
EKTVGQDALGFIGVSRDGRIFYAYNTDGMLIGYMRDDGEIYVASQHPVKVKVV
HHHCCCCCCEEEEECCCCEEEEEECCCCEEEEEEECCCEEEEECCCCEEEEEC
>Mature Secondary Structure
MVIQWFTHSCLRVLNYSSNLYYDGENMVKALILHGGAGSWRDESIRVKAEKVIEECTRRA
CEEEHHHHHHHHHHCCCCCEEECCHHHEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHH
WRILGESNNALNTVVEAVRCMEDSGILNAGYGSTLDLLGGRSLDAGLMTSTGLLGAVAAV
HHHHCCCCCHHHHHHHHHHHHHCCCCEECCCCCEEHHCCCCCCCCCHHHHHHHHHHHHHH
KATRNPILLARIVAEETPHVLLAGGSADELAMLKGLPPLPPPPPHVVERYVQAGRKLLGG
HHCCCCEEEEEEHHCCCCEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
DLKQDYYMKIREFVYRHGSSYYTMLKELVNVYDTVGAVALDEKGVLAAATSTGGVILKLP
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCEEEECC
GRVGDTPIPGAGFYASSTTACSATGIGEYIIRVMPCLRLDMEVSGGMDLEEALGKIMYYT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHEEHH
EKTVGQDALGFIGVSRDGRIFYAYNTDGMLIGYMRDDGEIYVASQHPVKVKVV
HHHCCCCCCEEEEECCCCEEEEEECCCCEEEEEEECCCEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]