Click here to switch to the map view.

The map label for this gene is pucD [H]

Identifier: 218883686

GI number: 218883686

Start: 346848

End: 349253

Strand: Reverse

Name: pucD [H]

Synonym: DKAM_0375

Alternate gene names: 218883686

Gene position: 349253-346848 (Counterclockwise)

Preceding gene: 218883687

Following gene: 218883683

Centisome position: 25.58

GC content: 46.84

Gene sequence:

>2406_bases
ATGAGTAAGCCCGAGTATGTTGAAATAGTTGAAAAGATATTCAATGAAACAAGGAGTAAGCCTACGAAGGACTTCAAGTA
TATAGGTAAGCATGTAGTGAGATGGGACGCCATAAGTAAGGCAACAGGTAAGCCAATATTCACAGCGGATCTAATTAATC
TATTAAAGAACCCCGTATTCGTCTACAGCGTTAGATCCAAGTATGCCCATGCATTAATCAAGGGTATCGATGTATCAGAG
GCAGTTAACTACCCAGGTGTGATAAAAGTTATAACATCCAGGGATATACCGGGTATAAATGACGTTGGCTATGTACTACC
GGATCAACCACTTATAGCCGATAGAAAGGTAAGGTATATAGGGGATACCGTAGCACTAATAGTGGCTGAGAGCCTTGAGA
ACGCCAGAGACGCTGGGGAAAGAGTCCACGTTGACTACGAGCCATTAGAGGTATACCTAGACCCGTTGCAGATAATTGAA
TGGAATGGATTAAAGGAGAAGCCTCATACATTAATACATGATGAACGTGGAAGCGACGTATTAACGAGGTACAAGATCAG
AGTTGGAGACGTAGAGAAAGCATTCAAGGAGGCCAGCGTCATAGTTGAGAACGAGTATAGGACACCTATGCAGGAACACG
CCTATCTTGAGCCAGAGGTGGCAATAGCAATACCCGAGCCGGATGGAGGAGTTACAATATATGCTAAGACGCAGTGCCCC
TTCGATACAAGGAAAGCTGTTTCAAACGTATTAGGACTACCATTCAACATGATAAGGGTCATAGCTCCAGCACTGGGTGG
AGGTTTCGGCGGCGCTGAGGACGTGGGCAACGAGATAGCTGCTAAAGCCGCGTTAGCAGCTCTATACACGAAGAAACCAG
CGGTTGTATTACATACAAGGGAAGAATCCATAATAGGACACACGAAGAGGCACCCGATTATCGCTAGATACAAGCATGCA
GCTAGGAGAGATGGAACATTACTCGGCGTCGAGGCCGAGATAATACTAGATAAGGGAGCATACGCTAGCCTCGGCCCATT
CGTCACATGGAGGGCGATAGTACATAGCACCGGGCCCTACAGGGTTCCCAACGCGAAAATAGATCTCGCAGCGGTGTACA
CGAATAAAGTTCCCGGAGGAGCGTTCAGAGGCTTCGGTAACCCACAGGTAACATTCGCGGTTGAAAGGCAGATGGATATA
CTTGCTGAGGAACTAGGCTTGGACCCAGTGGAGATAAGACTTAGGAACGCGTTGAGACCAGGTGATAGAACGGTTCATGG
ACAATTACTGGATCACGGCGTTGGACTAGTAGATGCTATCAAGAAAGCAGTTGAATTAAGCGGGTGGTATGAGAAGAGGA
AACTGTACTCCGAGGCCAAGGGTACTATTAGGCGTGGAATAGGCATAGCCGTATTCTACCATGGAAACAGTATTGGCGCG
GAGGGAGCCGACTACTCGTCTGTAACACTAATCATACAGAGGGATGGAAGCATAATATTTAGGACAGGGTTAACCGATAT
GGGCCAAGGCTCTATCCAGGGCTTAATCAATATAGCTGCTGAAATACTGGGTGTCCCGCCAAGCTACTTCAAAGTAGAGT
TACCGGATACAGCATCAACACCTGATGCAGGACCCACGGTTGCGTCTAGAAGCACTGCGATGGGCGGTAATGCAACACTT
GTGGCGGCATATAAGCTAAGAAAAAGACTCAATGAGCTAGCCTCCTCTATGCTTGGATGTAGTAGCCCTGATGACGTTGT
AATAGATGCTCCAAAGGTTTATTGCAGAGACGACCCAGAACACTATATAACATGGAAAGAACTAGTGGAGCAATCTTTCT
GGAAAGGTGTTCCACTGCAAGAATTCGGCTACTATAGGGCTCCACCGGCAGAGTGGCATGAGGAGACAGGCACCGGTCAA
CCCTACTTCACATACACATTTGGCGCCATAGTGAGTGATGTGGAGGTAGACCTCGAAACAGGAGTTGTGAGAGTAAAAGA
CGCTGTAACAGTATATGATATTGGAAGAGTAATCAATCGGACTGGTGCAGAGCACCACGGTGTTGGAGGATATATCCAGG
GTATGGGATACGCCCTAATGGAGGATACGTATTATAGCCCTGAAGGACACGTCTACAATACAAACTTATCGACATACCAT
ATACCCACAGGCCTGGATATTCCAGAGAGAATACTAGTAGACTTCGTGGAGGCAGGGTATATTAGGGGGCCGTTTGGAGC
TAAGGGGCTTGGAGAACCCTCTATAGTTGGCATAGCTCCAAGCATCGCCAATGCTGTAGCGCATGCATTAGGGAGTAAAG
ATGCGAACAGGGATGTAAATAGAATACCATTAACCCCAGATACGGTGTTCAGCATCATAAAGAAGCGTGGATTAAATAAG
AGGTAA

Upstream 100 bases:

>100_bases
CAAGCTTGCAGCCAAGTACATCAATGAGGGCAAGATCTACTTCGATGAAAAACAGGTGAGAGAAAAGTATCATTTAAAAG
TTGTCTAGTAGGTGGTTCAC

Downstream 100 bases:

>100_bases
TAGGTTTTAACCATATTCTTCTTTTTCCCTTATACCACTTTCCCTCCTCTCCCTTAAGTTAGATTCAATGCCGTAGTATA
GGCTTCAGCAATCCATGGTC

Product: aldehyde oxidase and xanthine dehydrogenase family protein, large subunit

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 801; Mature: 800

Protein sequence:

>801_residues
MSKPEYVEIVEKIFNETRSKPTKDFKYIGKHVVRWDAISKATGKPIFTADLINLLKNPVFVYSVRSKYAHALIKGIDVSE
AVNYPGVIKVITSRDIPGINDVGYVLPDQPLIADRKVRYIGDTVALIVAESLENARDAGERVHVDYEPLEVYLDPLQIIE
WNGLKEKPHTLIHDERGSDVLTRYKIRVGDVEKAFKEASVIVENEYRTPMQEHAYLEPEVAIAIPEPDGGVTIYAKTQCP
FDTRKAVSNVLGLPFNMIRVIAPALGGGFGGAEDVGNEIAAKAALAALYTKKPAVVLHTREESIIGHTKRHPIIARYKHA
ARRDGTLLGVEAEIILDKGAYASLGPFVTWRAIVHSTGPYRVPNAKIDLAAVYTNKVPGGAFRGFGNPQVTFAVERQMDI
LAEELGLDPVEIRLRNALRPGDRTVHGQLLDHGVGLVDAIKKAVELSGWYEKRKLYSEAKGTIRRGIGIAVFYHGNSIGA
EGADYSSVTLIIQRDGSIIFRTGLTDMGQGSIQGLINIAAEILGVPPSYFKVELPDTASTPDAGPTVASRSTAMGGNATL
VAAYKLRKRLNELASSMLGCSSPDDVVIDAPKVYCRDDPEHYITWKELVEQSFWKGVPLQEFGYYRAPPAEWHEETGTGQ
PYFTYTFGAIVSDVEVDLETGVVRVKDAVTVYDIGRVINRTGAEHHGVGGYIQGMGYALMEDTYYSPEGHVYNTNLSTYH
IPTGLDIPERILVDFVEAGYIRGPFGAKGLGEPSIVGIAPSIANAVAHALGSKDANRDVNRIPLTPDTVFSIIKKRGLNK
R

Sequences:

>Translated_801_residues
MSKPEYVEIVEKIFNETRSKPTKDFKYIGKHVVRWDAISKATGKPIFTADLINLLKNPVFVYSVRSKYAHALIKGIDVSE
AVNYPGVIKVITSRDIPGINDVGYVLPDQPLIADRKVRYIGDTVALIVAESLENARDAGERVHVDYEPLEVYLDPLQIIE
WNGLKEKPHTLIHDERGSDVLTRYKIRVGDVEKAFKEASVIVENEYRTPMQEHAYLEPEVAIAIPEPDGGVTIYAKTQCP
FDTRKAVSNVLGLPFNMIRVIAPALGGGFGGAEDVGNEIAAKAALAALYTKKPAVVLHTREESIIGHTKRHPIIARYKHA
ARRDGTLLGVEAEIILDKGAYASLGPFVTWRAIVHSTGPYRVPNAKIDLAAVYTNKVPGGAFRGFGNPQVTFAVERQMDI
LAEELGLDPVEIRLRNALRPGDRTVHGQLLDHGVGLVDAIKKAVELSGWYEKRKLYSEAKGTIRRGIGIAVFYHGNSIGA
EGADYSSVTLIIQRDGSIIFRTGLTDMGQGSIQGLINIAAEILGVPPSYFKVELPDTASTPDAGPTVASRSTAMGGNATL
VAAYKLRKRLNELASSMLGCSSPDDVVIDAPKVYCRDDPEHYITWKELVEQSFWKGVPLQEFGYYRAPPAEWHEETGTGQ
PYFTYTFGAIVSDVEVDLETGVVRVKDAVTVYDIGRVINRTGAEHHGVGGYIQGMGYALMEDTYYSPEGHVYNTNLSTYH
IPTGLDIPERILVDFVEAGYIRGPFGAKGLGEPSIVGIAPSIANAVAHALGSKDANRDVNRIPLTPDTVFSIIKKRGLNK
R
>Mature_800_residues
SKPEYVEIVEKIFNETRSKPTKDFKYIGKHVVRWDAISKATGKPIFTADLINLLKNPVFVYSVRSKYAHALIKGIDVSEA
VNYPGVIKVITSRDIPGINDVGYVLPDQPLIADRKVRYIGDTVALIVAESLENARDAGERVHVDYEPLEVYLDPLQIIEW
NGLKEKPHTLIHDERGSDVLTRYKIRVGDVEKAFKEASVIVENEYRTPMQEHAYLEPEVAIAIPEPDGGVTIYAKTQCPF
DTRKAVSNVLGLPFNMIRVIAPALGGGFGGAEDVGNEIAAKAALAALYTKKPAVVLHTREESIIGHTKRHPIIARYKHAA
RRDGTLLGVEAEIILDKGAYASLGPFVTWRAIVHSTGPYRVPNAKIDLAAVYTNKVPGGAFRGFGNPQVTFAVERQMDIL
AEELGLDPVEIRLRNALRPGDRTVHGQLLDHGVGLVDAIKKAVELSGWYEKRKLYSEAKGTIRRGIGIAVFYHGNSIGAE
GADYSSVTLIIQRDGSIIFRTGLTDMGQGSIQGLINIAAEILGVPPSYFKVELPDTASTPDAGPTVASRSTAMGGNATLV
AAYKLRKRLNELASSMLGCSSPDDVVIDAPKVYCRDDPEHYITWKELVEQSFWKGVPLQEFGYYRAPPAEWHEETGTGQP
YFTYTFGAIVSDVEVDLETGVVRVKDAVTVYDIGRVINRTGAEHHGVGGYIQGMGYALMEDTYYSPEGHVYNTNLSTYHI
PTGLDIPERILVDFVEAGYIRGPFGAKGLGEPSIVGIAPSIANAVAHALGSKDANRDVNRIPLTPDTVFSIIKKRGLNKR

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=775, Percent_Identity=28.3870967741935, Blast_Score=304, Evalue=3e-82,
Organism=Homo sapiens, GI71773480, Length=773, Percent_Identity=27.0375161707633, Blast_Score=266, Evalue=5e-71,
Organism=Escherichia coli, GI1789230, Length=791, Percent_Identity=31.3527180783818, Blast_Score=326, Evalue=4e-90,
Organism=Escherichia coli, GI1789246, Length=803, Percent_Identity=27.8953922789539, Blast_Score=262, Evalue=7e-71,
Organism=Escherichia coli, GI1786478, Length=787, Percent_Identity=25.7941550190597, Blast_Score=171, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17540638, Length=758, Percent_Identity=26.9129287598945, Blast_Score=231, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI32566215, Length=810, Percent_Identity=24.9382716049383, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17539860, Length=789, Percent_Identity=24.9683143219265, Blast_Score=159, Evalue=6e-39,
Organism=Drosophila melanogaster, GI17737937, Length=752, Percent_Identity=29.5212765957447, Blast_Score=276, Evalue=5e-74,
Organism=Drosophila melanogaster, GI24647193, Length=784, Percent_Identity=24.1071428571429, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24647199, Length=790, Percent_Identity=23.2911392405063, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24647195, Length=805, Percent_Identity=23.6024844720497, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24647197, Length=778, Percent_Identity=23.7789203084833, Blast_Score=146, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24647201, Length=789, Percent_Identity=23.3206590621039, Blast_Score=140, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 87726; Mature: 87595

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPEYVEIVEKIFNETRSKPTKDFKYIGKHVVRWDAISKATGKPIFTADLINLLKNPVF
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
VYSVRSKYAHALIKGIDVSEAVNYPGVIKVITSRDIPGINDVGYVLPDQPLIADRKVRYI
EEEHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHH
GDTVALIVAESLENARDAGERVHVDYEPLEVYLDPLQIIEWNGLKEKPHTLIHDERGSDV
CHHHHHHHHHHHHHHHCCCCEEEECCCHHHEEECCEEEEECCCCCCCCCCEEECCCCCCC
LTRYKIRVGDVEKAFKEASVIVENEYRTPMQEHAYLEPEVAIAIPEPDGGVTIYAKTQCP
EEEEEEEECHHHHHHHHHHEEEECCCCCCHHHCCCCCCCEEEEEECCCCCEEEEEECCCC
FDTRKAVSNVLGLPFNMIRVIAPALGGGFGGAEDVGNEIAAKAALAALYTKKPAVVLHTR
CHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
EESIIGHTKRHPIIARYKHAARRDGTLLGVEAEIILDKGAYASLGPFVTWRAIVHSTGPY
CHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCC
RVPNAKIDLAAVYTNKVPGGAFRGFGNPQVTFAVERQMDILAEELGLDPVEIRLRNALRP
CCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHCCCC
GDRTVHGQLLDHGVGLVDAIKKAVELSGWYEKRKLYSEAKGTIRRGIGIAVFYHGNSIGA
CCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
EGADYSSVTLIIQRDGSIIFRTGLTDMGQGSIQGLINIAAEILGVPPSYFKVELPDTAST
CCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
PDAGPTVASRSTAMGGNATLVAAYKLRKRLNELASSMLGCSSPDDVVIDAPKVYCRDDPE
CCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEECCCCH
HYITWKELVEQSFWKGVPLQEFGYYRAPPAEWHEETGTGQPYFTYTFGAIVSDVEVDLET
HEEEHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHCCCCCCCEEEEEHHHHHHCCEEECCC
GVVRVKDAVTVYDIGRVINRTGAEHHGVGGYIQGMGYALMEDTYYSPEGHVYNTNLSTYH
CEEEEECCEEHHHHHHHHHHCCCCCCCCCCHHHCCCEEEECCCEECCCCCEEECCCEEEE
IPTGLDIPERILVDFVEAGYIRGPFGAKGLGEPSIVGIAPSIANAVAHALGSKDANRDVN
CCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCC
RIPLTPDTVFSIIKKRGLNKR
CCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKPEYVEIVEKIFNETRSKPTKDFKYIGKHVVRWDAISKATGKPIFTADLINLLKNPVF
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
VYSVRSKYAHALIKGIDVSEAVNYPGVIKVITSRDIPGINDVGYVLPDQPLIADRKVRYI
EEEHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHH
GDTVALIVAESLENARDAGERVHVDYEPLEVYLDPLQIIEWNGLKEKPHTLIHDERGSDV
CHHHHHHHHHHHHHHHCCCCEEEECCCHHHEEECCEEEEECCCCCCCCCCEEECCCCCCC
LTRYKIRVGDVEKAFKEASVIVENEYRTPMQEHAYLEPEVAIAIPEPDGGVTIYAKTQCP
EEEEEEEECHHHHHHHHHHEEEECCCCCCHHHCCCCCCCEEEEEECCCCCEEEEEECCCC
FDTRKAVSNVLGLPFNMIRVIAPALGGGFGGAEDVGNEIAAKAALAALYTKKPAVVLHTR
CHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
EESIIGHTKRHPIIARYKHAARRDGTLLGVEAEIILDKGAYASLGPFVTWRAIVHSTGPY
CHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCC
RVPNAKIDLAAVYTNKVPGGAFRGFGNPQVTFAVERQMDILAEELGLDPVEIRLRNALRP
CCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHCCCC
GDRTVHGQLLDHGVGLVDAIKKAVELSGWYEKRKLYSEAKGTIRRGIGIAVFYHGNSIGA
CCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
EGADYSSVTLIIQRDGSIIFRTGLTDMGQGSIQGLINIAAEILGVPPSYFKVELPDTAST
CCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
PDAGPTVASRSTAMGGNATLVAAYKLRKRLNELASSMLGCSSPDDVVIDAPKVYCRDDPE
CCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEECCCCH
HYITWKELVEQSFWKGVPLQEFGYYRAPPAEWHEETGTGQPYFTYTFGAIVSDVEVDLET
HEEEHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHCCCCCCCEEEEEHHHHHHCCEEECCC
GVVRVKDAVTVYDIGRVINRTGAEHHGVGGYIQGMGYALMEDTYYSPEGHVYNTNLSTYH
CEEEEECCEEHHHHHHHHHHCCCCCCCCCCHHHCCCEEEECCCEECCCCCEEECCCEEEE
IPTGLDIPERILVDFVEAGYIRGPFGAKGLGEPSIVGIAPSIANAVAHALGSKDANRDVN
CCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCC
RIPLTPDTVFSIIKKRGLNKR
CCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]