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The map label for this gene is hcrC [H]

Identifier: 218883687

GI number: 218883687

Start: 349266

End: 349799

Strand: Reverse

Name: hcrC [H]

Synonym: DKAM_0376

Alternate gene names: 218883687

Gene position: 349799-349266 (Counterclockwise)

Preceding gene: 218883688

Following gene: 218883686

Centisome position: 25.62

GC content: 47.38

Gene sequence:

>534_bases
TTGGCGGGGATCGTTAAAGTCAGGTTAGAGGTTAATGGTAGGGAGTACATAGTTGATGTACCTCCTCATGAGAGGTTAAT
TGACACACTAAGGTATAGACTAGGTTATACAAGTGTTAGAGAGGGATGTGGTAGAGGGGAATGCGGAACATGCATAGTCC
TCGTGAACGGGTTACCAAGGCACTCATGTCTCACGCTAACATCCACGCTTGATGGAGCCAAGATAACGACTGTGGAAGGC
CTGGCCCCCGAGGGCAAGCTACACGCTATCCAAGTAGCATTCATCGAGACCAGAGGCATGCAATGCGGTTTCTGTACATC
GGGCTTCATAATGATGACTAAGGCGTTGCTCGACCATAATCCAAACCCAAGCTACGACGAAATAAAGGAGTGGCTTAGCA
GCACATTGTGCAGGTGTGGGAGCTACCACTACTACTTTGCAGCAGCCAAGCTTGCAGCCAAGTACATCAATGAGGGCAAG
ATCTACTTCGATGAAAAACAGGTGAGAGAAAAGTATCATTTAAAAGTTGTCTAG

Upstream 100 bases:

>100_bases
TGGTGGGCTACCAGTGAATACAGGCTTGAAATGTCTAAGGCTATTTTAAGGAAGGGTCTGCGCCTCGTACACAATAGAAT
CCTAAACGGGGTGATGTAGG

Downstream 100 bases:

>100_bases
TAGGTGGTTCACATGAGTAAGCCCGAGTATGTTGAAATAGTTGAAAAGATATTCAATGAAACAAGGAGTAAGCCTACGAA
GGACTTCAAGTATATAGGTA

Product: aldehyde oxidase and xanthine dehydrogenase family protein, small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MAGIVKVRLEVNGREYIVDVPPHERLIDTLRYRLGYTSVREGCGRGECGTCIVLVNGLPRHSCLTLTSTLDGAKITTVEG
LAPEGKLHAIQVAFIETRGMQCGFCTSGFIMMTKALLDHNPNPSYDEIKEWLSSTLCRCGSYHYYFAAAKLAAKYINEGK
IYFDEKQVREKYHLKVV

Sequences:

>Translated_177_residues
MAGIVKVRLEVNGREYIVDVPPHERLIDTLRYRLGYTSVREGCGRGECGTCIVLVNGLPRHSCLTLTSTLDGAKITTVEG
LAPEGKLHAIQVAFIETRGMQCGFCTSGFIMMTKALLDHNPNPSYDEIKEWLSSTLCRCGSYHYYFAAAKLAAKYINEGK
IYFDEKQVREKYHLKVV
>Mature_176_residues
AGIVKVRLEVNGREYIVDVPPHERLIDTLRYRLGYTSVREGCGRGECGTCIVLVNGLPRHSCLTLTSTLDGAKITTVEGL
APEGKLHAIQVAFIETRGMQCGFCTSGFIMMTKALLDHNPNPSYDEIKEWLSSTLCRCGSYHYYFAAAKLAAKYINEGKI
YFDEKQVREKYHLKVV

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=36.1842105263158, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI91823271, Length=149, Percent_Identity=34.2281879194631, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786480, Length=168, Percent_Identity=40.4761904761905, Blast_Score=123, Evalue=6e-30,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=39.7163120567376, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=134, Percent_Identity=39.5522388059701, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=32.0261437908497, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=30.718954248366, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737937, Length=145, Percent_Identity=34.4827586206897, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=33.5403726708075, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=33.5403726708075, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647199, Length=152, Percent_Identity=31.5789473684211, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24647201, Length=149, Percent_Identity=31.5436241610738, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647193, Length=165, Percent_Identity=30.9090909090909, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR017606
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 19841; Mature: 19710

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGIVKVRLEVNGREYIVDVPPHERLIDTLRYRLGYTSVREGCGRGECGTCIVLVNGLPR
CCCEEEEEEEECCCEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEECCCCC
HSCLTLTSTLDGAKITTVEGLAPEGKLHAIQVAFIETRGMQCGFCTSGFIMMTKALLDHN
CCEEEEEECCCCCEEEEECCCCCCCCEEEEEEEEEEECCCEECCCCCCHHHHHHHHHCCC
PNPSYDEIKEWLSSTLCRCGSYHYYFAAAKLAAKYINEGKIYFDEKQVREKYHLKVV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHCEECC
>Mature Secondary Structure 
AGIVKVRLEVNGREYIVDVPPHERLIDTLRYRLGYTSVREGCGRGECGTCIVLVNGLPR
CCEEEEEEEECCCEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEECCCCC
HSCLTLTSTLDGAKITTVEGLAPEGKLHAIQVAFIETRGMQCGFCTSGFIMMTKALLDHN
CCEEEEEECCCCCEEEEECCCCCCCCEEEEEEEEEEECCCEECCCCCCHHHHHHHHHCCC
PNPSYDEIKEWLSSTLCRCGSYHYYFAAAKLAAKYINEGKIYFDEKQVREKYHLKVV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]