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The map label for this gene is 218883536

Identifier: 218883536

GI number: 218883536

Start: 208442

End: 209545

Strand: Reverse

Name: 218883536

Synonym: DKAM_0225

Alternate gene names: NA

Gene position: 209545-208442 (Counterclockwise)

Preceding gene: 218883539

Following gene: 218883533

Centisome position: 15.35

GC content: 47.55

Gene sequence:

>1104_bases
ATGGTGGACCCCAGGATCTCTAATCTAGCCCGCCTTATAGTCAACTATTGTGTATATCTGAGGAAAGGGGAAGAAGTCGT
AATCAATGCCTCAGTTGAATCAATACCGTTGGTCAGAGAGATAGTCAGATATACCGTGGAGGCCGGGGCTTACCCAGTAT
TCATAAATATAGGTGATGAATCAATAACCGAGGCATTCTACAAGTATGCACCACAAGAAGTCCTCTCACATGTAAGCATA
CTCGAGAAGGAAATCGTGTCGAGAGTGAACGCGCAGATAAGCATACTCTCACCATCCCACACTAAGCCGCTTATCGGAAT
AGACCCGGAGAAGCTTAAGGTGAGGAGTCAGGCTAGAAGGGAGCTAAATAAAATATACTTGGAGAGAAGCGCGAAGGGTG
AGCTGAAATGGGTTATAGCCCCATATCCAACGAGGGCATTAGCCCAGGAAGCCGGTATGAGTATAAGTGAATACGAAGAC
TTCGTCTACCACGCCACATACGCTGACTCAGCTGACCCGGTATCTGTGTGGAGCGAGATCGGGAAGAGACAGCAGAGGAT
AGCTGAGTTCCTGAATAAGGCCAGGGAGATAAGATACGTGGGCCCCGGGATAGACCTCTATCTACGCGTGGATGGAAGAA
CATGGATTAATGATGATGGACACTACAATATGCCTGGTGGCGAGGTATTCTCAGCCCCTGTAGAGGATAGTGTCGAGGGA
TATGTGGAGTTCGAGTATCCGGCCATATGGCGTGGTGTAGAAGTAGAAGGTGTTAAATTGGTCTTCAGAAAAGGCGAGGT
AGTAGAGGCTACCGCTAGACGCGGCGAGGCATTTTTAAAGAAGATGCTTGAAACGGATGATGGAGCCAGGAAAGTGGGTG
AGATAGCATTCGGGTTGAACTATAATATAACCAGGTTCACTAAGGAAATACTGTTCGACGAGAAGATCGGGGGCACAATA
CATCTAGCCCTAGGTTCGGCTTACCCTGAGACAGGTGGGAGGAATGTTTCAGCAATACACTGGGATATGATTAAGGACAT
GAGGAACGCGAAGGTCTACGTGGATAACGAGTTAATCTATGAAAACGGTCGGTTCATAATCTAG

Upstream 100 bases:

>100_bases
GTTCAACTGCTTATTTAATGCCTCGATTAACTCAGGGTGCATATGGGACACCTAAAATTATTTTATTGTATTCGATCATT
TTAAATCATTGGTGTATTGC

Downstream 100 bases:

>100_bases
CCTGTTGCGGGTTGAAGCTTTTCATAGATCGTTTTCCCACTCACTATATCGCTTAACCCGGTTTTATCCTCTATAATAAC
AGTATAGCTGATCAGCCCAT

Product: peptidase M29, aminopeptidase II

Products: NA

Alternate protein names: Aminopeptidase II; AP-II [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MVDPRISNLARLIVNYCVYLRKGEEVVINASVESIPLVREIVRYTVEAGAYPVFINIGDESITEAFYKYAPQEVLSHVSI
LEKEIVSRVNAQISILSPSHTKPLIGIDPEKLKVRSQARRELNKIYLERSAKGELKWVIAPYPTRALAQEAGMSISEYED
FVYHATYADSADPVSVWSEIGKRQQRIAEFLNKAREIRYVGPGIDLYLRVDGRTWINDDGHYNMPGGEVFSAPVEDSVEG
YVEFEYPAIWRGVEVEGVKLVFRKGEVVEATARRGEAFLKKMLETDDGARKVGEIAFGLNYNITRFTKEILFDEKIGGTI
HLALGSAYPETGGRNVSAIHWDMIKDMRNAKVYVDNELIYENGRFII

Sequences:

>Translated_367_residues
MVDPRISNLARLIVNYCVYLRKGEEVVINASVESIPLVREIVRYTVEAGAYPVFINIGDESITEAFYKYAPQEVLSHVSI
LEKEIVSRVNAQISILSPSHTKPLIGIDPEKLKVRSQARRELNKIYLERSAKGELKWVIAPYPTRALAQEAGMSISEYED
FVYHATYADSADPVSVWSEIGKRQQRIAEFLNKAREIRYVGPGIDLYLRVDGRTWINDDGHYNMPGGEVFSAPVEDSVEG
YVEFEYPAIWRGVEVEGVKLVFRKGEVVEATARRGEAFLKKMLETDDGARKVGEIAFGLNYNITRFTKEILFDEKIGGTI
HLALGSAYPETGGRNVSAIHWDMIKDMRNAKVYVDNELIYENGRFII
>Mature_367_residues
MVDPRISNLARLIVNYCVYLRKGEEVVINASVESIPLVREIVRYTVEAGAYPVFINIGDESITEAFYKYAPQEVLSHVSI
LEKEIVSRVNAQISILSPSHTKPLIGIDPEKLKVRSQARRELNKIYLERSAKGELKWVIAPYPTRALAQEAGMSISEYED
FVYHATYADSADPVSVWSEIGKRQQRIAEFLNKAREIRYVGPGIDLYLRVDGRTWINDDGHYNMPGGEVFSAPVEDSVEG
YVEFEYPAIWRGVEVEGVKLVFRKGEVVEATARRGEAFLKKMLETDDGARKVGEIAFGLNYNITRFTKEILFDEKIGGTI
HLALGSAYPETGGRNVSAIHWDMIKDMRNAKVYVDNELIYENGRFII

Specific function: Broad specificity metal-dependent exopeptidase, releasing all N-terminal amino acids [H]

COG id: COG2309

COG function: function code E; Leucyl aminopeptidase (aminopeptidase T)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M29 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000787 [H]

Pfam domain/function: PF02073 Peptidase_M29 [H]

EC number: NA

Molecular weight: Translated: 41551; Mature: 41551

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDPRISNLARLIVNYCVYLRKGEEVVINASVESIPLVREIVRYTVEAGAYPVFINIGDE
CCCCHHHHHHHHHHHHHHHEECCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCH
SITEAFYKYAPQEVLSHVSILEKEIVSRVNAQISILSPSHTKPLIGIDPEKLKVRSQARR
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHH
ELNKIYLERSAKGELKWVIAPYPTRALAQEAGMSISEYEDFVYHATYADSADPVSVWSEI
HHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHEEEEECCCCCCHHHHHHHH
GKRQQRIAEFLNKAREIRYVGPGIDLYLRVDGRTWINDDGHYNMPGGEVFSAPVEDSVEG
HHHHHHHHHHHHHHHEEEEECCCEEEEEEECCCEEECCCCCCCCCCCCEEECCCCCCCCC
YVEFEYPAIWRGVEVEGVKLVFRKGEVVEATARRGEAFLKKMLETDDGARKVGEIAFGLN
EEEEECCCEECCCEECCEEEEEECCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCC
YNITRFTKEILFDEKIGGTIHLALGSAYPETGGRNVSAIHWDMIKDMRNAKVYVDNELIY
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHCCCEEEECCEEEE
ENGRFII
ECCCEEC
>Mature Secondary Structure
MVDPRISNLARLIVNYCVYLRKGEEVVINASVESIPLVREIVRYTVEAGAYPVFINIGDE
CCCCHHHHHHHHHHHHHHHEECCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCH
SITEAFYKYAPQEVLSHVSILEKEIVSRVNAQISILSPSHTKPLIGIDPEKLKVRSQARR
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHH
ELNKIYLERSAKGELKWVIAPYPTRALAQEAGMSISEYEDFVYHATYADSADPVSVWSEI
HHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHEEEEECCCCCCHHHHHHHH
GKRQQRIAEFLNKAREIRYVGPGIDLYLRVDGRTWINDDGHYNMPGGEVFSAPVEDSVEG
HHHHHHHHHHHHHHHEEEEECCCEEEEEEECCCEEECCCCCCCCCCCCEEECCCCCCCCC
YVEFEYPAIWRGVEVEGVKLVFRKGEVVEATARRGEAFLKKMLETDDGARKVGEIAFGLN
EEEEECCCEECCCEECCEEEEEECCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCC
YNITRFTKEILFDEKIGGTIHLALGSAYPETGGRNVSAIHWDMIKDMRNAKVYVDNELIY
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHCCCEEEECCEEEE
ENGRFII
ECCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9362117; 938681 [H]