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The map label for this gene is moaA [H]

Identifier: 218883525

GI number: 218883525

Start: 199108

End: 200022

Strand: Reverse

Name: moaA [H]

Synonym: DKAM_0214

Alternate gene names: 218883525

Gene position: 200022-199108 (Counterclockwise)

Preceding gene: 218883526

Following gene: 218883524

Centisome position: 14.65

GC content: 41.97

Gene sequence:

>915_bases
ATGTTGGTTGATAGGTTCGGTAGGAAAATAGATAGCTTCAGGATCGCTGTAACCTCGAGATGCAACTATCAATGCATATT
TTGCCACCGGGAAGGAATGATGAATGACCAGGGGAATGAAGCATTAGATGCCGGGGACTATGGCTTCTTAACCGAGGTAG
CGGTAAAACATGGCATAAAATCCTTCAAGCTAACTGGAGGGGAGCCCTTGGTGAGGAGTGATATAGTAGATATAGTTAGA
GAGATAGCCATCTATACAAGGGACGTCTCAATGACTACGAATGGGAGTTTATTACTTGAAAAAGTAGGATTGCTTGCCGA
GGCTGGGTTAAATAGAATCAATGTAAGCATACACTCCCTTAAGCCCCCCGTATATAGATTTATAACCGGGGGATCCACGC
TACTCGAGAAGGTCTTGAAAGGCGTTGACGAGGCATTGAACCATGGAATCAAGGTTAAAATAGATTTCTTAGTAATGAAG
GTGAACATTGATGAAGTAAAGAATATAATAGAATACGCGTCGGATAAGGGACTTGACGTAAACATCATAGAGCTTATACC
CCTTGGGATACCACAAGATGTCTACAGGGATCAGCATGTTATAGTGGATCCGATTATAGAGTTTCTCGAGAAAAACTCCA
TCGCTAAAACAGTAAGGGAGTTCCAGAGTAGGCCAGAGTACATTATGCCAAGCGGTATAAAGGTAGATGTTGTAAAAGGG
TATGGAAATCCAGCTCTTTGTTCAAGGTGTACAAGGCTTAGGCTTACACCGGAGGGATGGATCAAGACATGCCTATTTGT
AAATAAACCAATAGTAGATATATCTAGGGAGCTTAAGAATAGGGATGAGAAAGGAGTTATAAACGGTATAAAGAGAGCTG
TTTACTTGAGGGAGCCATTCTTTAAACCTGGGTGA

Upstream 100 bases:

>100_bases
ATGAGTGGTCCAAGCTAAATGATTTCGGGGGAGGTAAGAGGATACTCCTCTATATGAGCAGGGAGCACACCTACTTAATC
GATCAGGAAAGTGGTTAAAA

Downstream 100 bases:

>100_bases
TCCACTTGGGCATCAGAATGGCTGATATAACCGGGAAGGAGGACGTGTACAGGGAGGCAACGGCGACAGGCTATATAAAA
CTTAAGCCTTCAACCATAGA

Product: putative molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLVDRFGRKIDSFRIAVTSRCNYQCIFCHREGMMNDQGNEALDAGDYGFLTEVAVKHGIKSFKLTGGEPLVRSDIVDIVR
EIAIYTRDVSMTTNGSLLLEKVGLLAEAGLNRINVSIHSLKPPVYRFITGGSTLLEKVLKGVDEALNHGIKVKIDFLVMK
VNIDEVKNIIEYASDKGLDVNIIELIPLGIPQDVYRDQHVIVDPIIEFLEKNSIAKTVREFQSRPEYIMPSGIKVDVVKG
YGNPALCSRCTRLRLTPEGWIKTCLFVNKPIVDISRELKNRDEKGVINGIKRAVYLREPFFKPG

Sequences:

>Translated_304_residues
MLVDRFGRKIDSFRIAVTSRCNYQCIFCHREGMMNDQGNEALDAGDYGFLTEVAVKHGIKSFKLTGGEPLVRSDIVDIVR
EIAIYTRDVSMTTNGSLLLEKVGLLAEAGLNRINVSIHSLKPPVYRFITGGSTLLEKVLKGVDEALNHGIKVKIDFLVMK
VNIDEVKNIIEYASDKGLDVNIIELIPLGIPQDVYRDQHVIVDPIIEFLEKNSIAKTVREFQSRPEYIMPSGIKVDVVKG
YGNPALCSRCTRLRLTPEGWIKTCLFVNKPIVDISRELKNRDEKGVINGIKRAVYLREPFFKPG
>Mature_304_residues
MLVDRFGRKIDSFRIAVTSRCNYQCIFCHREGMMNDQGNEALDAGDYGFLTEVAVKHGIKSFKLTGGEPLVRSDIVDIVR
EIAIYTRDVSMTTNGSLLLEKVGLLAEAGLNRINVSIHSLKPPVYRFITGGSTLLEKVLKGVDEALNHGIKVKIDFLVMK
VNIDEVKNIIEYASDKGLDVNIIELIPLGIPQDVYRDQHVIVDPIIEFLEKNSIAKTVREFQSRPEYIMPSGIKVDVVKG
YGNPALCSRCTRLRLTPEGWIKTCLFVNKPIVDISRELKNRDEKGVINGIKRAVYLREPFFKPG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=291, Percent_Identity=31.2714776632302, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI22027536, Length=291, Percent_Identity=31.2714776632302, Blast_Score=117, Evalue=9e-27,
Organism=Escherichia coli, GI1786999, Length=283, Percent_Identity=27.9151943462898, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32566329, Length=280, Percent_Identity=30, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32566331, Length=280, Percent_Identity=30, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17561210, Length=283, Percent_Identity=28.6219081272085, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574488, Length=287, Percent_Identity=31.3588850174216, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28574490, Length=287, Percent_Identity=31.3588850174216, Blast_Score=124, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013485
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 34166; Mature: 34166

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDRFGRKIDSFRIAVTSRCNYQCIFCHREGMMNDQGNEALDAGDYGFLTEVAVKHGIK
CCCHHHCCHHHHEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
SFKLTGGEPLVRSDIVDIVREIAIYTRDVSMTTNGSLLLEKVGLLAEAGLNRINVSIHSL
EEEECCCCCHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHCCCCEEEEEEECC
KPPVYRFITGGSTLLEKVLKGVDEALNHGIKVKIDFLVMKVNIDEVKNIIEYASDKGLDV
CCCHHEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECHHHHHHHHHHHCCCCCCE
NIIELIPLGIPQDVYRDQHVIVDPIIEFLEKNSIAKTVREFQSRPEYIMPSGIKVDVVKG
EEEEEEECCCCHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEEEEC
YGNPALCSRCTRLRLTPEGWIKTCLFVNKPIVDISRELKNRDEKGVINGIKRAVYLREPF
CCCHHHHHHHHHCEECCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
FKPG
CCCC
>Mature Secondary Structure
MLVDRFGRKIDSFRIAVTSRCNYQCIFCHREGMMNDQGNEALDAGDYGFLTEVAVKHGIK
CCCHHHCCHHHHEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
SFKLTGGEPLVRSDIVDIVREIAIYTRDVSMTTNGSLLLEKVGLLAEAGLNRINVSIHSL
EEEECCCCCHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHCCCCEEEEEEECC
KPPVYRFITGGSTLLEKVLKGVDEALNHGIKVKIDFLVMKVNIDEVKNIIEYASDKGLDV
CCCHHEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECHHHHHHHHHHHCCCCCCE
NIIELIPLGIPQDVYRDQHVIVDPIIEFLEKNSIAKTVREFQSRPEYIMPSGIKVDVVKG
EEEEEEECCCCHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEEEEC
YGNPALCSRCTRLRLTPEGWIKTCLFVNKPIVDISRELKNRDEKGVINGIKRAVYLREPF
CCCHHHHHHHHHCEECCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
FKPG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA