Click here to switch to the map view.

The map label for this gene is moaC [H]

Identifier: 218883524

GI number: 218883524

Start: 198662

End: 199090

Strand: Reverse

Name: moaC [H]

Synonym: DKAM_0213

Alternate gene names: 218883524

Gene position: 199090-198662 (Counterclockwise)

Preceding gene: 218883525

Following gene: 218883523

Centisome position: 14.58

GC content: 42.19

Gene sequence:

>429_bases
ATGGCTGATATAACCGGGAAGGAGGACGTGTACAGGGAGGCAACGGCGACAGGCTATATAAAACTTAAGCCTTCAACCAT
AGAAATTATTAAAAAAGGGCTTGTTGAGAAGGGAGACGTGTTTTCAGTGTCAACAATAGCAGCTATAATGAGTGTTAAGG
AGACACCTAGAATACTGCCTTTAACACATAACATCCCCATAACAAATGTCAAAGTTGATTTCGAGGTACTCGATGACGGC
ATAAGAGTCTATATAACAGTTAAGACAACGGCTAGGACAGGGGTGGAAATGGAGGCTTTAACAGGTGCGGCCATAGCATT
ACTGAACATATGGGATATGGTTAAGAAATACGAGAAGAATGAAGACGGGCAATACCCATATACGGTTATAACTGATCTCA
GAGTCGTAGAGAAGAAGAAAGGGGTGTAG

Upstream 100 bases:

>100_bases
TTAAGAATAGGGATGAGAAAGGAGTTATAAACGGTATAAAGAGAGCTGTTTACTTGAGGGAGCCATTCTTTAAACCTGGG
TGATCCACTTGGGCATCAGA

Downstream 100 bases:

>100_bases
CCATGAGGATCACTATCAGGTCGTACTCCATATTCTCGGATTTCCTTGGAAACGAAGTGAGAATCGAGCTCGATGAGTCT
ATCACGGTGGGCGAGCTACT

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MADITGKEDVYREATATGYIKLKPSTIEIIKKGLVEKGDVFSVSTIAAIMSVKETPRILPLTHNIPITNVKVDFEVLDDG
IRVYITVKTTARTGVEMEALTGAAIALLNIWDMVKKYEKNEDGQYPYTVITDLRVVEKKKGV

Sequences:

>Translated_142_residues
MADITGKEDVYREATATGYIKLKPSTIEIIKKGLVEKGDVFSVSTIAAIMSVKETPRILPLTHNIPITNVKVDFEVLDDG
IRVYITVKTTARTGVEMEALTGAAIALLNIWDMVKKYEKNEDGQYPYTVITDLRVVEKKKGV
>Mature_141_residues
ADITGKEDVYREATATGYIKLKPSTIEIIKKGLVEKGDVFSVSTIAAIMSVKETPRILPLTHNIPITNVKVDFEVLDDGI
RVYITVKTTARTGVEMEALTGAAIALLNIWDMVKKYEKNEDGQYPYTVITDLRVVEKKKGV

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=143, Percent_Identity=35.6643356643357, Blast_Score=92, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566331, Length=141, Percent_Identity=31.9148936170213, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28574492, Length=143, Percent_Identity=34.965034965035, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28574490, Length=143, Percent_Identity=34.965034965035, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 15761; Mature: 15629

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADITGKEDVYREATATGYIKLKPSTIEIIKKGLVEKGDVFSVSTIAAIMSVKETPRILP
CCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCEEE
LTHNIPITNVKVDFEVLDDGIRVYITVKTTARTGVEMEALTGAAIALLNIWDMVKKYEKN
EECCCCEEEEEEEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EDGQYPYTVITDLRVVEKKKGV
CCCCCCEEEEEHHEEEHHCCCC
>Mature Secondary Structure 
ADITGKEDVYREATATGYIKLKPSTIEIIKKGLVEKGDVFSVSTIAAIMSVKETPRILP
CCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCEEE
LTHNIPITNVKVDFEVLDDGIRVYITVKTTARTGVEMEALTGAAIALLNIWDMVKKYEKN
EECCCCEEEEEEEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EDGQYPYTVITDLRVVEKKKGV
CCCCCCEEEEEHHEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA