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The map label for this gene is lgrB [H]

Identifier: 218532966

GI number: 218532966

Start: 5450124

End: 5453585

Strand: Reverse

Name: lgrB [H]

Synonym: Mchl_5090

Alternate gene names: 218532966

Gene position: 5453585-5450124 (Counterclockwise)

Preceding gene: 218532967

Following gene: 218532965

Centisome position: 94.39

GC content: 73.19

Gene sequence:

>3462_bases
ATGTCCTGCATCGACGGCGAAGCTGTTTTCCAGTCGATCCCGGCCCGTTACGCCGCGCCCGGTTCGGGCGGGGAGGGGCG
GCCGGTCGTCCCCCTCGCCACGCCGACGCCGGAGGAACTGCAGGAGGTCTTCCGGCATCAGCTCGATGCCGTGTGCCGCG
TGGTGGAGGAGCAGCTTCGCACGCTCGCGCTGACCTTCACAGCCGCGCGGGTGAGCCTGCCGGAACCGCACTCATCGCCG
GCTCTGCCGATGGCGGATCGCGGGGCAGAGCGGCCGCTGACCGACGGGGAGGCCGAGATCTGGCTCGCCGCGCAGTTCGG
CGCCGACGCCAATGCCGCGATGACCGAGATCGTCACCCTGCGGCTCGACGGGCCGCTCGACGCCGAGCGGCTTCTCTCCG
TCGTGAGAGCGGTGCTCGGCCGCTACGACGCCCTGCGCAGCCGCTTCTCCCCGAGCGGCGAGACCGTGCGGATCGATCCC
GCAGGCCTCGTGCCGGTGCGGTGGGTCGATCTCGCAGGCGAATCCGATCCGGAGGCCGCTCTAGCGGCGCATCTTCACGC
GCAAGCGGGCCTCTCGTTCGATCCGGTCGCCGGCCCGGTGGCGCGGGCCGACCTCGTTCGCCTCGGCGAGGGGCATCACA
TCCTCGTCCTCTCGGCCCACCACATCGCCTGCGACGGCTGGTCCTTCGCGGTCCTGGCCGACGCGATCGCGAGCGCCTAT
CGCGCTGCGCCGGAGGAGCTGGCTCCGGCCCCGCAGACCACGGGCTGTGCCCCATCGGAGGCGGAGGCGAGCCGGGCGCT
GGATTACTGGGCCGAGCTCTATGCGAGCTTGCCCGAACCGCTCGACCTGCCGGCCGACCATCCGCGGCCAAAGCTGCGCG
GCTTTGCCGGCGACACCCGAAGCGCCACCTTGCCGCTGCCGCTCGTCGCCGCGCTGAAAGCGCTCGCGGCGCGCCAGGGG
CAGACGCTGAACGCCACGCTGCTCGCGGCCTTTCAGGTGCTCCTCGCGCGGCTCTCGGGGCAGGACGACCTCGTCGTCGG
CGTGCCGATGGCGGGCCAGCCGCGCCGCGGCGAGCCGGGCCTCGTCGGGCACCACGCCGATTTCCTGCCGCTGCGGGCCC
GGTTCGACCCGGACGAGCCCTTCGCTGCCCATCTCGCCCGCACCGGCGCAGCCTTGGCCGAGGCCGCCGCTAACGCGGAC
TGCACCCTAGGGCGGCTGCTGCGCCACCTCGACCGACCGCACGATCCGGCGCGCCCGCCGCTGGCGCAGGTGCAGTTCAA
CCTCCAGCGTTTCGCCGACGCCATCGATTTCGGGGCGGGCCTGCGCGGCACCCTTGCACCCGCGCCGAAGCGCTTCTCGA
CGTTCGAACTCACCGTCAGCCTCAGCGAGACCGCCGACGGGCTGACCGTTGACGCCACCTACAACCGCGCCCTGTTCGAG
CCGGCCACGATCGAGCGCTGGATCGGGCACTACCTCACCCTGCTCGGGCATCTCGCCCGCGATCCCGCGCAGCCGGTCGG
GCGCGTTCCGCTGCTCGCTGCAGCCGAGCGGCAGACCATGCTGGTGGACTGGAACGCGACCGAGACAGCCCATCCGCTCA
AGGTCGGGGCGATGCGCGCCTTCAGCCTCCACGCCCGGCGCGACCCGGACCGGATCGCGATCCGTTTCGGCGAAGAGACC
GTCTCCTACGGCGCCCTCGACCGCTGGGCCGATCGCGTCGCCGCGGCGTTGCAGGGAAGCGCTCTGCCCGAGGGGGCCCG
CGTCGGCCTGCTCATGCGCCGCTCGCCCGGCCTCGTCGCGGCGATGCTCGGCGCTTTGCGCGCCGGCATCCCTTACGTCC
CGCTCGACCCGGCGATGCCGCCTGCCCGCCGCGCGGGAATCGTCGCCGATGCCGGGATCGGCGCGATGCTCACGCTCGCG
GCCGACCGCGCGCTCCTGCCGGAGGGCCCCCGAGTCATTGAGGTCGATCGTCTCGCCGGGCCGGCGCCGACCCGCTTCCC
GCGCGTGCCGGCGGAGCGGGCCGCCTACCTGATCTACACGTCGAGCACGACCGGCGCGCCGAAGGGCGTCGAGGTGCTGC
ATCGCGGCCTTTCGAACCTGCTGTTCTCGATGGCCCAGGCACCGGGAATCGCTCGTGACGACCGGCTGCTGGCGGTGACG
ACGGTCACCTTCGACATCGCCGGGCTCGAATTGCTGCTGCCGCTGATCCGCGGCGCCCAGATCGTGCTCGCCTCCGCCGA
GGAGGCGCGCGACGGCCACGCCCTCCTCGCCCGCCTGGAACGGGGCGAGGCCACCATGCTCCAGGCGACGCCGATGACGT
GGCGGCTCCTGCTGGAGGCGGGTTTCCGCTCGCGCCCCGGCTTCAAGATGCTGTGCGGCGGTGAAGCGCTTCCGCTCGAT
CTGGCCCGGCGCCTCACCGAGGGCGGAGGCGAACTCTGGAACCTCTACGGGCCGACGGAGACGACGATCTGGTCCTCGGC
CGCGCGGGTCGATCCGGAGGAGGAGACGGTCACGGTCGGGCGGCCGATCGACAACACCAGCCTGTTCATCCTCGACGCGC
AGGACGAGCCGGTGCCGGTCGGGGTCACGGGTGAATTGCTGATCGGCGGGATCGGGCTCGCCCGCGGCTATCTCGGACGG
CCGGACCTGACGCAGCGCAGCTTCATCGCCAGTGCGCTGCCGGAATGCGCCGGGGGGCGGCTCTACCGGACCGGCGACCG
GGCGCGCTACCGGCCGGACGGACGCGTCGAGATCCTGGGACGGGCCGACCACCAGATCAAGCTGCGCGGCTACCGGATCG
AGCCCGCTGAGATCGAGGCGGTGCTGCTGCGCCAGACCGGGCTGCACGCCGTCGTGGTGCTGCGCCCCGACGCGGCGGGC
GAGGATCGCCTCGTCTGCTACTTCGTGCGCCCCGAGGGCGAGGCAGCGCCCACCCTGCGCAATCTGCGCGCCGCGCTCGC
CCGCGAACTCCCGGATTACATGATCCCCTCGGAATGGGTCCGACTGCCGGCCCTGCCGCTGACGGCGAGCGGAAAGGTCG
ATCGCCGGGCGCTGCCCGCTCCCGAGGCCCGGCCCACCGGCCCCGCCGAGCCGGCCGCCGCGATCAAGCTTACCCTCAAG
CCTGCTCCGGTCCCGGCATCCGACGACGGCCTCGAGACCACCCTCGCGGCGATCTGGCGGGAGGTGCTGGGGCTCGCCAG
TGTGGAGAGGGACGACGACCTGATCGCACTCGGGGCGGATTCGCTCAGCGTGTTCCGCATCGTCGCGCGGGCGCGGCGTG
AGAACCTGCCGCTCGGGGCCGGCGACCTGTTTCAGGAACGCACCATCGCCCGGGTCGCGGCCCTGCTGCACGGGCGCCTC
GGGGAGGGAGGCGGAACACCGGCCGCCGCGCGCGCGCCGATCCCGTCGATCCGGCGCCCAAGGACTGCCGACGCCGACCG
CGCCGCGGTCGGTCAGGCGTGA

Upstream 100 bases:

>100_bases
ATCGCCGAGAGCGCCCGGTTCCAACCCGGCGGCGCGGCTGGCGTCCGGTGCGGGATGCCCGGCCTCCGCCGATGAGCCGC
ACGGCCAGACGAGGATCGGG

Downstream 100 bases:

>100_bases
GGGCGGGCGGGATGCGGCATTTCACGCAGGAATCGCCGGCCATGACCGGCGAGGTTCACGGCGGCGACGCCTTCACAGCC
CGCTGCTCCCACAGCCAGAC

Product: amino acid adenylation protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1153; Mature: 1152

Protein sequence:

>1153_residues
MSCIDGEAVFQSIPARYAAPGSGGEGRPVVPLATPTPEELQEVFRHQLDAVCRVVEEQLRTLALTFTAARVSLPEPHSSP
ALPMADRGAERPLTDGEAEIWLAAQFGADANAAMTEIVTLRLDGPLDAERLLSVVRAVLGRYDALRSRFSPSGETVRIDP
AGLVPVRWVDLAGESDPEAALAAHLHAQAGLSFDPVAGPVARADLVRLGEGHHILVLSAHHIACDGWSFAVLADAIASAY
RAAPEELAPAPQTTGCAPSEAEASRALDYWAELYASLPEPLDLPADHPRPKLRGFAGDTRSATLPLPLVAALKALAARQG
QTLNATLLAAFQVLLARLSGQDDLVVGVPMAGQPRRGEPGLVGHHADFLPLRARFDPDEPFAAHLARTGAALAEAAANAD
CTLGRLLRHLDRPHDPARPPLAQVQFNLQRFADAIDFGAGLRGTLAPAPKRFSTFELTVSLSETADGLTVDATYNRALFE
PATIERWIGHYLTLLGHLARDPAQPVGRVPLLAAAERQTMLVDWNATETAHPLKVGAMRAFSLHARRDPDRIAIRFGEET
VSYGALDRWADRVAAALQGSALPEGARVGLLMRRSPGLVAAMLGALRAGIPYVPLDPAMPPARRAGIVADAGIGAMLTLA
ADRALLPEGPRVIEVDRLAGPAPTRFPRVPAERAAYLIYTSSTTGAPKGVEVLHRGLSNLLFSMAQAPGIARDDRLLAVT
TVTFDIAGLELLLPLIRGAQIVLASAEEARDGHALLARLERGEATMLQATPMTWRLLLEAGFRSRPGFKMLCGGEALPLD
LARRLTEGGGELWNLYGPTETTIWSSAARVDPEEETVTVGRPIDNTSLFILDAQDEPVPVGVTGELLIGGIGLARGYLGR
PDLTQRSFIASALPECAGGRLYRTGDRARYRPDGRVEILGRADHQIKLRGYRIEPAEIEAVLLRQTGLHAVVVLRPDAAG
EDRLVCYFVRPEGEAAPTLRNLRAALARELPDYMIPSEWVRLPALPLTASGKVDRRALPAPEARPTGPAEPAAAIKLTLK
PAPVPASDDGLETTLAAIWREVLGLASVERDDDLIALGADSLSVFRIVARARRENLPLGAGDLFQERTIARVAALLHGRL
GEGGGTPAAARAPIPSIRRPRTADADRAAVGQA

Sequences:

>Translated_1153_residues
MSCIDGEAVFQSIPARYAAPGSGGEGRPVVPLATPTPEELQEVFRHQLDAVCRVVEEQLRTLALTFTAARVSLPEPHSSP
ALPMADRGAERPLTDGEAEIWLAAQFGADANAAMTEIVTLRLDGPLDAERLLSVVRAVLGRYDALRSRFSPSGETVRIDP
AGLVPVRWVDLAGESDPEAALAAHLHAQAGLSFDPVAGPVARADLVRLGEGHHILVLSAHHIACDGWSFAVLADAIASAY
RAAPEELAPAPQTTGCAPSEAEASRALDYWAELYASLPEPLDLPADHPRPKLRGFAGDTRSATLPLPLVAALKALAARQG
QTLNATLLAAFQVLLARLSGQDDLVVGVPMAGQPRRGEPGLVGHHADFLPLRARFDPDEPFAAHLARTGAALAEAAANAD
CTLGRLLRHLDRPHDPARPPLAQVQFNLQRFADAIDFGAGLRGTLAPAPKRFSTFELTVSLSETADGLTVDATYNRALFE
PATIERWIGHYLTLLGHLARDPAQPVGRVPLLAAAERQTMLVDWNATETAHPLKVGAMRAFSLHARRDPDRIAIRFGEET
VSYGALDRWADRVAAALQGSALPEGARVGLLMRRSPGLVAAMLGALRAGIPYVPLDPAMPPARRAGIVADAGIGAMLTLA
ADRALLPEGPRVIEVDRLAGPAPTRFPRVPAERAAYLIYTSSTTGAPKGVEVLHRGLSNLLFSMAQAPGIARDDRLLAVT
TVTFDIAGLELLLPLIRGAQIVLASAEEARDGHALLARLERGEATMLQATPMTWRLLLEAGFRSRPGFKMLCGGEALPLD
LARRLTEGGGELWNLYGPTETTIWSSAARVDPEEETVTVGRPIDNTSLFILDAQDEPVPVGVTGELLIGGIGLARGYLGR
PDLTQRSFIASALPECAGGRLYRTGDRARYRPDGRVEILGRADHQIKLRGYRIEPAEIEAVLLRQTGLHAVVVLRPDAAG
EDRLVCYFVRPEGEAAPTLRNLRAALARELPDYMIPSEWVRLPALPLTASGKVDRRALPAPEARPTGPAEPAAAIKLTLK
PAPVPASDDGLETTLAAIWREVLGLASVERDDDLIALGADSLSVFRIVARARRENLPLGAGDLFQERTIARVAALLHGRL
GEGGGTPAAARAPIPSIRRPRTADADRAAVGQA
>Mature_1152_residues
SCIDGEAVFQSIPARYAAPGSGGEGRPVVPLATPTPEELQEVFRHQLDAVCRVVEEQLRTLALTFTAARVSLPEPHSSPA
LPMADRGAERPLTDGEAEIWLAAQFGADANAAMTEIVTLRLDGPLDAERLLSVVRAVLGRYDALRSRFSPSGETVRIDPA
GLVPVRWVDLAGESDPEAALAAHLHAQAGLSFDPVAGPVARADLVRLGEGHHILVLSAHHIACDGWSFAVLADAIASAYR
AAPEELAPAPQTTGCAPSEAEASRALDYWAELYASLPEPLDLPADHPRPKLRGFAGDTRSATLPLPLVAALKALAARQGQ
TLNATLLAAFQVLLARLSGQDDLVVGVPMAGQPRRGEPGLVGHHADFLPLRARFDPDEPFAAHLARTGAALAEAAANADC
TLGRLLRHLDRPHDPARPPLAQVQFNLQRFADAIDFGAGLRGTLAPAPKRFSTFELTVSLSETADGLTVDATYNRALFEP
ATIERWIGHYLTLLGHLARDPAQPVGRVPLLAAAERQTMLVDWNATETAHPLKVGAMRAFSLHARRDPDRIAIRFGEETV
SYGALDRWADRVAAALQGSALPEGARVGLLMRRSPGLVAAMLGALRAGIPYVPLDPAMPPARRAGIVADAGIGAMLTLAA
DRALLPEGPRVIEVDRLAGPAPTRFPRVPAERAAYLIYTSSTTGAPKGVEVLHRGLSNLLFSMAQAPGIARDDRLLAVTT
VTFDIAGLELLLPLIRGAQIVLASAEEARDGHALLARLERGEATMLQATPMTWRLLLEAGFRSRPGFKMLCGGEALPLDL
ARRLTEGGGELWNLYGPTETTIWSSAARVDPEEETVTVGRPIDNTSLFILDAQDEPVPVGVTGELLIGGIGLARGYLGRP
DLTQRSFIASALPECAGGRLYRTGDRARYRPDGRVEILGRADHQIKLRGYRIEPAEIEAVLLRQTGLHAVVVLRPDAAGE
DRLVCYFVRPEGEAAPTLRNLRAALARELPDYMIPSEWVRLPALPLTASGKVDRRALPAPEARPTGPAEPAAAIKLTLKP
APVPASDDGLETTLAAIWREVLGLASVERDDDLIALGADSLSVFRIVARARRENLPLGAGDLFQERTIARVAALLHGRLG
EGGGTPAAARAPIPSIRRPRTADADRAAVGQA

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=621, Percent_Identity=23.0273752012882, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI156151445, Length=541, Percent_Identity=23.6598890942699, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI187761345, Length=485, Percent_Identity=24.9484536082474, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI187761343, Length=485, Percent_Identity=24.9484536082474, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI157311624, Length=498, Percent_Identity=23.0923694779116, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI157311622, Length=498, Percent_Identity=23.0923694779116, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI38505220, Length=362, Percent_Identity=25.9668508287293, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI58082049, Length=499, Percent_Identity=23.2464929859719, Blast_Score=80, Evalue=8e-15,
Organism=Escherichia coli, GI1786801, Length=676, Percent_Identity=32.5443786982249, Blast_Score=245, Evalue=1e-65,
Organism=Escherichia coli, GI145693145, Length=509, Percent_Identity=24.5579567779961, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1788107, Length=533, Percent_Identity=25.515947467167, Blast_Score=93, Evalue=8e-20,
Organism=Escherichia coli, GI1786810, Length=504, Percent_Identity=24.8015873015873, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17556356, Length=548, Percent_Identity=27.1897810218978, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17550940, Length=935, Percent_Identity=21.9251336898396, Blast_Score=129, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994690, Length=535, Percent_Identity=23.9252336448598, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994694, Length=535, Percent_Identity=23.9252336448598, Blast_Score=104, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994703, Length=535, Percent_Identity=23.9252336448598, Blast_Score=104, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564422, Length=371, Percent_Identity=25.8760107816712, Blast_Score=102, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI32564420, Length=371, Percent_Identity=25.8760107816712, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560308, Length=355, Percent_Identity=27.0422535211268, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17558820, Length=496, Percent_Identity=23.5887096774194, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563687, Length=494, Percent_Identity=21.0526315789474, Blast_Score=81, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=965, Percent_Identity=22.5906735751295, Blast_Score=158, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6319699, Length=381, Percent_Identity=24.4094488188976, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24648676, Length=635, Percent_Identity=27.5590551181102, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24656500, Length=500, Percent_Identity=25.4, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24581924, Length=528, Percent_Identity=24.4318181818182, Blast_Score=76, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582852, Length=477, Percent_Identity=22.4318658280922, Blast_Score=73, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 122895; Mature: 122764

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCIDGEAVFQSIPARYAAPGSGGEGRPVVPLATPTPEELQEVFRHQLDAVCRVVEEQLR
CCCCCHHHHHHHCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
TLALTFTAARVSLPEPHSSPALPMADRGAERPLTDGEAEIWLAAQFGADANAAMTEIVTL
HHHHEEEEHEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEE
RLDGPLDAERLLSVVRAVLGRYDALRSRFSPSGETVRIDPAGLVPVRWVDLAGESDPEAA
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCCHHH
LAAHLHAQAGLSFDPVAGPVARADLVRLGEGHHILVLSAHHIACDGWSFAVLADAIASAY
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECEEEECCCHHHHHHHHHHHHH
RAAPEELAPAPQTTGCAPSEAEASRALDYWAELYASLPEPLDLPADHPRPKLRGFAGDTR
HCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCC
SATLPLPLVAALKALAARQGQTLNATLLAAFQVLLARLSGQDDLVVGVPMAGQPRRGEPG
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC
LVGHHADFLPLRARFDPDEPFAAHLARTGAALAEAAANADCTLGRLLRHLDRPHDPARPP
EECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC
LAQVQFNLQRFADAIDFGAGLRGTLAPAPKRFSTFELTVSLSETADGLTVDATYNRALFE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEEECCCHHCC
PATIERWIGHYLTLLGHLARDPAQPVGRVPLLAAAERQTMLVDWNATETAHPLKVGAMRA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHE
FSLHARRDPDRIAIRFGEETVSYGALDRWADRVAAALQGSALPEGARVGLLMRRSPGLVA
EEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHH
AMLGALRAGIPYVPLDPAMPPARRAGIVADAGIGAMLTLAADRALLPEGPRVIEVDRLAG
HHHHHHHCCCCCCCCCCCCCCHHHCCEEECCCCCHHHHHHHCCCCCCCCCCEEEECCCCC
PAPTRFPRVPAERAAYLIYTSSTTGAPKGVEVLHRGLSNLLFSMAQAPGIARDDRLLAVT
CCCCCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
TVTFDIAGLELLLPLIRGAQIVLASAEEARDGHALLARLERGEATMLQATPMTWRLLLEA
EEEEEHHHHHHHHHHHCCCEEEEECCHHCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHH
GFRSRPGFKMLCGGEALPLDLARRLTEGGGELWNLYGPTETTIWSSAARVDPEEETVTVG
CCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCHHHCCCHHCCCCCCCEEEEC
RPIDNTSLFILDAQDEPVPVGVTGELLIGGIGLARGYLGRPDLTQRSFIASALPECAGGR
CCCCCCEEEEEECCCCCEEECCCHHHHEECHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
LYRTGDRARYRPDGRVEILGRADHQIKLRGYRIEPAEIEAVLLRQTGLHAVVVLRPDAAG
EEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCHHHHHEEEEEECCCEEEEEECCCCCC
EDRLVCYFVRPEGEAAPTLRNLRAALARELPDYMIPSEWVRLPALPLTASGKVDRRALPA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
PEARPTGPAEPAAAIKLTLKPAPVPASDDGLETTLAAIWREVLGLASVERDDDLIALGAD
CCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
SLSVFRIVARARRENLPLGAGDLFQERTIARVAALLHGRLGEGGGTPAAARAPIPSIRRP
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
RTADADRAAVGQA
CCCCCCCHHCCCC
>Mature Secondary Structure 
SCIDGEAVFQSIPARYAAPGSGGEGRPVVPLATPTPEELQEVFRHQLDAVCRVVEEQLR
CCCCHHHHHHHCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
TLALTFTAARVSLPEPHSSPALPMADRGAERPLTDGEAEIWLAAQFGADANAAMTEIVTL
HHHHEEEEHEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEE
RLDGPLDAERLLSVVRAVLGRYDALRSRFSPSGETVRIDPAGLVPVRWVDLAGESDPEAA
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCCHHH
LAAHLHAQAGLSFDPVAGPVARADLVRLGEGHHILVLSAHHIACDGWSFAVLADAIASAY
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECEEEECCCHHHHHHHHHHHHH
RAAPEELAPAPQTTGCAPSEAEASRALDYWAELYASLPEPLDLPADHPRPKLRGFAGDTR
HCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCC
SATLPLPLVAALKALAARQGQTLNATLLAAFQVLLARLSGQDDLVVGVPMAGQPRRGEPG
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC
LVGHHADFLPLRARFDPDEPFAAHLARTGAALAEAAANADCTLGRLLRHLDRPHDPARPP
EECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC
LAQVQFNLQRFADAIDFGAGLRGTLAPAPKRFSTFELTVSLSETADGLTVDATYNRALFE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEEECCCHHCC
PATIERWIGHYLTLLGHLARDPAQPVGRVPLLAAAERQTMLVDWNATETAHPLKVGAMRA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHE
FSLHARRDPDRIAIRFGEETVSYGALDRWADRVAAALQGSALPEGARVGLLMRRSPGLVA
EEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHH
AMLGALRAGIPYVPLDPAMPPARRAGIVADAGIGAMLTLAADRALLPEGPRVIEVDRLAG
HHHHHHHCCCCCCCCCCCCCCHHHCCEEECCCCCHHHHHHHCCCCCCCCCCEEEECCCCC
PAPTRFPRVPAERAAYLIYTSSTTGAPKGVEVLHRGLSNLLFSMAQAPGIARDDRLLAVT
CCCCCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
TVTFDIAGLELLLPLIRGAQIVLASAEEARDGHALLARLERGEATMLQATPMTWRLLLEA
EEEEEHHHHHHHHHHHCCCEEEEECCHHCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHH
GFRSRPGFKMLCGGEALPLDLARRLTEGGGELWNLYGPTETTIWSSAARVDPEEETVTVG
CCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCHHHCCCHHCCCCCCCEEEEC
RPIDNTSLFILDAQDEPVPVGVTGELLIGGIGLARGYLGRPDLTQRSFIASALPECAGGR
CCCCCCEEEEEECCCCCEEECCCHHHHEECHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
LYRTGDRARYRPDGRVEILGRADHQIKLRGYRIEPAEIEAVLLRQTGLHAVVVLRPDAAG
EEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCHHHHHEEEEEECCCEEEEEECCCCCC
EDRLVCYFVRPEGEAAPTLRNLRAALARELPDYMIPSEWVRLPALPLTASGKVDRRALPA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
PEARPTGPAEPAAAIKLTLKPAPVPASDDGLETTLAAIWREVLGLASVERDDDLIALGAD
CCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
SLSVFRIVARARRENLPLGAGDLFQERTIARVAALLHGRLGEGGGTPAAARAPIPSIRRP
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
RTADADRAAVGQA
CCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA