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The map label for this gene is hsaB [H]

Identifier: 218532937

GI number: 218532937

Start: 5413440

End: 5414012

Strand: Reverse

Name: hsaB [H]

Synonym: Mchl_5060

Alternate gene names: 218532937

Gene position: 5414012-5413440 (Counterclockwise)

Preceding gene: 218532940

Following gene: 218532936

Centisome position: 93.7

GC content: 72.08

Gene sequence:

>573_bases
ATGGCCGCCGCGCTGGCGCCGGAGCCCGCCATCGACGGGGGGCTTCTCAAGCAGGCGATGCGCCGCCTCGTCGGCGGGGT
CGTCGTGATCACCGCCGGAACCGGCGAGGACCGGGTCGGGCTCACTGCGACCTCGGCCGTCTCCCTCTCCGTCGATCCGC
CGACCATGCTGGTCTGCGTCAACCGCGCCTCCTCGACCTGGCCGGTCATCGCCCGGCGGCGGCATTTCTGCGTCAGCATC
CTCGGGGCCGGGCAGCAGGCCACCGCCGAGCGCTTCGCCGGCATCGGCGGGCTGCGGGGCGCCGCCCGCTATCGCGGCGC
GGATTGGACGATCATGGCATCGGGCGCCTCCGGCCTCACCGAGGCGCAGGCCATCGTCGATTGCGCGCTGGAGGAGGTCA
TCGAGCGGCACAGCCACGCCATCCTCCTCGGCGCGGTACGCGCGGTGCGGCTGAACCGGTTGGAGCGGCCCTCCCTGGCC
TATGGCGGCGGGCGCTTCATCGGGATCTCACCGGATGAGGCGGCACGCGGCACCGGTCGCATTCACAGTGCCGCTGACAA
CAAGACAGATTAA

Upstream 100 bases:

>100_bases
CCCATTTCACATCGACGAACGGATTGCGAACCATGCTTGCGCACCGGAGATCATCGACACCGGTCACCTCGGCCGGCTCG
TTCGGCGGATGGGGGGCGTG

Downstream 100 bases:

>100_bases
CCAGCAACACACTTAATATCGATAAATGCTTTTTCGGCACAATCAGCAAGAGTATTGATAAAACTTAGGTCGTATTGAAA
TCGAAGCGGCCACAGATCAA

Product: flavin reductase domain protein FMN-binding

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MAAALAPEPAIDGGLLKQAMRRLVGGVVVITAGTGEDRVGLTATSAVSLSVDPPTMLVCVNRASSTWPVIARRRHFCVSI
LGAGQQATAERFAGIGGLRGAARYRGADWTIMASGASGLTEAQAIVDCALEEVIERHSHAILLGAVRAVRLNRLERPSLA
YGGGRFIGISPDEAARGTGRIHSAADNKTD

Sequences:

>Translated_190_residues
MAAALAPEPAIDGGLLKQAMRRLVGGVVVITAGTGEDRVGLTATSAVSLSVDPPTMLVCVNRASSTWPVIARRRHFCVSI
LGAGQQATAERFAGIGGLRGAARYRGADWTIMASGASGLTEAQAIVDCALEEVIERHSHAILLGAVRAVRLNRLERPSLA
YGGGRFIGISPDEAARGTGRIHSAADNKTD
>Mature_189_residues
AAALAPEPAIDGGLLKQAMRRLVGGVVVITAGTGEDRVGLTATSAVSLSVDPPTMLVCVNRASSTWPVIARRRHFCVSIL
GAGQQATAERFAGIGGLRGAARYRGADWTIMASGASGLTEAQAIVDCALEEVIERHSHAILLGAVRAVRLNRLERPSLAY
GGGRFIGISPDEAARGTGRIHSAADNKTD

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

Organism=Escherichia coli, GI87081819, Length=152, Percent_Identity=32.2368421052632, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 19711; Mature: 19580

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAALAPEPAIDGGLLKQAMRRLVGGVVVITAGTGEDRVGLTATSAVSLSVDPPTMLVCV
CCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEECEEEEEECCCEEEEEE
NRASSTWPVIARRRHFCVSILGAGQQATAERFAGIGGLRGAARYRGADWTIMASGASGLT
CCCCCCCHHHHHHHHHEEHEECCCCHHHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCH
EAQAIVDCALEEVIERHSHAILLGAVRAVRLNRLERPSLAYGGGRFIGISPDEAARGTGR
HHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCCCCEECCCCEEEEECCCHHCCCCCC
IHSAADNKTD
EECCCCCCCC
>Mature Secondary Structure 
AAALAPEPAIDGGLLKQAMRRLVGGVVVITAGTGEDRVGLTATSAVSLSVDPPTMLVCV
CCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEECEEEEEECCCEEEEEE
NRASSTWPVIARRRHFCVSILGAGQQATAERFAGIGGLRGAARYRGADWTIMASGASGLT
CCCCCCCHHHHHHHHHEEHEECCCCHHHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCH
EAQAIVDCALEEVIERHSHAILLGAVRAVRLNRLERPSLAYGGGRFIGISPDEAARGTGR
HHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCCCCEECCCCEEEEECCCHHCCCCCC
IHSAADNKTD
EECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA