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The map label for this gene is qorA [H]

Identifier: 218532878

GI number: 218532878

Start: 5346412

End: 5347434

Strand: Reverse

Name: qorA [H]

Synonym: Mchl_5001

Alternate gene names: 218532878

Gene position: 5347434-5346412 (Counterclockwise)

Preceding gene: 218532880

Following gene: 218532870

Centisome position: 92.55

GC content: 69.5

Gene sequence:

>1023_bases
ATGCAAGCCCTCCAGCTCTTCGGCGACCGAGATCTGCGCCTCACCGAGGTCGAGCCGCCGCCCGCGCCGGGACCGGGCGA
AGTGCAGATCCGGGTCCGGGCGGTCGGCCTCAACTTCATCGACGTGTGGGGCTTTCGCGGCATGGCCTTCGCCAAGCGCA
AGCTGCCGCTGACCGTCGGCGCGGAGGCTGCGGGTGAGATCGCGGCGGTCGGCGAGGGCGTCGAGGGGCTCTCCGTCGGC
GATGCGGTCGTGCCCTACGGCGCGCTGACCTGCGGCCGATGCCGCGCCTGCCAGGAGGGGCGAGATAACCTGTGCGAGGA
CGTCTCCGGCGTGATGGGCTTCCATCTCGACGGCTTCGCCCGTGAGCGGGTGAACCTGCCGGCCCGCCTCGTGGTGCGGG
TGCCGGGGGGCGTCGATCACGTCCAGGCGGCCTGCGCCGGCATCGCCTTCGGCACGGTGCAGCACATGCTGTTCGACAAC
GCGCGGCTAGAGCCGGGCGAGTCGATCCTCGTCCATGCCGGCGGCTCGGGCATCGGCACGGCGGCGATCAAGATGGCCAA
GGCGATCGGCTGCACCGTCTACACGACGGTCGGCGACGACGCGAAGGGCGAGAAGGCGAAGGCGCTCGGCGCCGACCACG
TCGTCAACTACCGCGAGGAGCGCTTCGAGGGCGAGGTGCGGCGGCTGACCAAGCGCAAGGGCGTGGACGTGGTGTTCGAG
CATGTCGGCGCCGAGACGTGGAACGGCTCGCTGCTCTGCCTGAAGCGCGGCGGGCGGCTCGTCACCTGCGGCTCGACCTC
CGGCGTGTCGGTGCAGATGAACCTGATGCAGTTGTTCCAGCAGCAATACCGCATCACCGGCTCGTTCGGCTGCCGCATCG
CCAATATGAGCCAGAGCCTCGACAAGATGGCCGCCGGCCTGACCCCGGTCATCGACACGGTGCTGCCGCTCGCCGATTTC
GCCAGCGGCCTGGAGCGCCTGGAATCGCGCAAGGTGTTCGGAAAAATTCTCGTGACGCTCTGA

Upstream 100 bases:

>100_bases
CGGTGCCCGCTGTTTCGCGGTACGGCGTCGGGCGACCCCGGCCGGGCCCGGTTCGTACGCCGCGCCAGTCCCTCTTCAAC
GCCAGACGAGTTCGATCCTG

Downstream 100 bases:

>100_bases
CGCGTTCAGGCGAAGAGGCGGCTGCCGAGGCCGGGAAGATCGCGAAAACTGTCCGCCACATGGCCCGCGAGCGCCCGCGC
CGCCGGCCCGGCACCGTCGC

Product: alcohol dehydrogenase zinc-binding domain protein

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQALQLFGDRDLRLTEVEPPPAPGPGEVQIRVRAVGLNFIDVWGFRGMAFAKRKLPLTVGAEAAGEIAAVGEGVEGLSVG
DAVVPYGALTCGRCRACQEGRDNLCEDVSGVMGFHLDGFARERVNLPARLVVRVPGGVDHVQAACAGIAFGTVQHMLFDN
ARLEPGESILVHAGGSGIGTAAIKMAKAIGCTVYTTVGDDAKGEKAKALGADHVVNYREERFEGEVRRLTKRKGVDVVFE
HVGAETWNGSLLCLKRGGRLVTCGSTSGVSVQMNLMQLFQQQYRITGSFGCRIANMSQSLDKMAAGLTPVIDTVLPLADF
ASGLERLESRKVFGKILVTL

Sequences:

>Translated_340_residues
MQALQLFGDRDLRLTEVEPPPAPGPGEVQIRVRAVGLNFIDVWGFRGMAFAKRKLPLTVGAEAAGEIAAVGEGVEGLSVG
DAVVPYGALTCGRCRACQEGRDNLCEDVSGVMGFHLDGFARERVNLPARLVVRVPGGVDHVQAACAGIAFGTVQHMLFDN
ARLEPGESILVHAGGSGIGTAAIKMAKAIGCTVYTTVGDDAKGEKAKALGADHVVNYREERFEGEVRRLTKRKGVDVVFE
HVGAETWNGSLLCLKRGGRLVTCGSTSGVSVQMNLMQLFQQQYRITGSFGCRIANMSQSLDKMAAGLTPVIDTVLPLADF
ASGLERLESRKVFGKILVTL
>Mature_340_residues
MQALQLFGDRDLRLTEVEPPPAPGPGEVQIRVRAVGLNFIDVWGFRGMAFAKRKLPLTVGAEAAGEIAAVGEGVEGLSVG
DAVVPYGALTCGRCRACQEGRDNLCEDVSGVMGFHLDGFARERVNLPARLVVRVPGGVDHVQAACAGIAFGTVQHMLFDN
ARLEPGESILVHAGGSGIGTAAIKMAKAIGCTVYTTVGDDAKGEKAKALGADHVVNYREERFEGEVRRLTKRKGVDVVFE
HVGAETWNGSLLCLKRGGRLVTCGSTSGVSVQMNLMQLFQQQYRITGSFGCRIANMSQSLDKMAAGLTPVIDTVLPLADF
ASGLERLESRKVFGKILVTL

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=349, Percent_Identity=27.7936962750716, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI22538444, Length=349, Percent_Identity=27.7936962750716, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI18379349, Length=338, Percent_Identity=26.3313609467456, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI194239674, Length=337, Percent_Identity=26.4094955489614, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI13236495, Length=337, Percent_Identity=26.4094955489614, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI24308257, Length=349, Percent_Identity=25.7879656160458, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI4501929, Length=364, Percent_Identity=29.9450549450549, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI67078404, Length=332, Percent_Identity=24.6987951807229, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI34577061, Length=352, Percent_Identity=27.5568181818182, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI41872631, Length=135, Percent_Identity=34.8148148148148, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI67078406, Length=324, Percent_Identity=25, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI28557745, Length=259, Percent_Identity=27.7992277992278, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4501933, Length=363, Percent_Identity=28.099173553719, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI194239676, Length=240, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI197927207, Length=178, Percent_Identity=27.5280898876405, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI156627571, Length=341, Percent_Identity=28.1524926686217, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI262073058, Length=350, Percent_Identity=25.1428571428571, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI71743840, Length=350, Percent_Identity=25.1428571428571, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790485, Length=338, Percent_Identity=31.0650887573964, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790045, Length=354, Percent_Identity=28.2485875706215, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788073, Length=320, Percent_Identity=28.125, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787863, Length=219, Percent_Identity=31.5068493150685, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI226510992, Length=315, Percent_Identity=28.2539682539683, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786518, Length=290, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081918, Length=289, Percent_Identity=24.9134948096886, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87082401, Length=256, Percent_Identity=27.734375, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=266, Percent_Identity=29.6992481203008, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562878, Length=324, Percent_Identity=28.3950617283951, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=320, Percent_Identity=21.875, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=324, Percent_Identity=21.9135802469136, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=246, Percent_Identity=26.0162601626016, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI212642053, Length=136, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324486, Length=325, Percent_Identity=25.5384615384615, Blast_Score=99, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=343, Percent_Identity=25.9475218658892, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6319621, Length=323, Percent_Identity=26.3157894736842, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=328, Percent_Identity=24.6951219512195, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6319520, Length=347, Percent_Identity=23.9193083573487, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322619, Length=342, Percent_Identity=23.3918128654971, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319955, Length=342, Percent_Identity=23.0994152046784, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323099, Length=328, Percent_Identity=25.609756097561, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221330659, Length=140, Percent_Identity=35, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920632, Length=140, Percent_Identity=35, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581345, Length=139, Percent_Identity=34.5323741007194, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 36170; Mature: 36170

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALQLFGDRDLRLTEVEPPPAPGPGEVQIRVRAVGLNFIDVWGFRGMAFAKRKLPLTVG
CCCHHHCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCEEEECCCCCHHHHHHCCCEEEC
AEAAGEIAAVGEGVEGLSVGDAVVPYGALTCGRCRACQEGRDNLCEDVSGVMGFHLDGFA
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RERVNLPARLVVRVPGGVDHVQAACAGIAFGTVQHMLFDNARLEPGESILVHAGGSGIGT
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
AAIKMAKAIGCTVYTTVGDDAKGEKAKALGADHVVNYREERFEGEVRRLTKRKGVDVVFE
HHHHHHHHHCEEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
HVGAETWNGSLLCLKRGGRLVTCGSTSGVSVQMNLMQLFQQQYRITGSFGCRIANMSQSL
HCCCCCCCCCEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHEECCCCCEEEEHHHHHH
DKMAAGLTPVIDTVLPLADFASGLERLESRKVFGKILVTL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MQALQLFGDRDLRLTEVEPPPAPGPGEVQIRVRAVGLNFIDVWGFRGMAFAKRKLPLTVG
CCCHHHCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCEEEECCCCCHHHHHHCCCEEEC
AEAAGEIAAVGEGVEGLSVGDAVVPYGALTCGRCRACQEGRDNLCEDVSGVMGFHLDGFA
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RERVNLPARLVVRVPGGVDHVQAACAGIAFGTVQHMLFDNARLEPGESILVHAGGSGIGT
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
AAIKMAKAIGCTVYTTVGDDAKGEKAKALGADHVVNYREERFEGEVRRLTKRKGVDVVFE
HHHHHHHHHCEEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
HVGAETWNGSLLCLKRGGRLVTCGSTSGVSVQMNLMQLFQQQYRITGSFGCRIANMSQSL
HCCCCCCCCCEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHEECCCCCEEEEHHHHHH
DKMAAGLTPVIDTVLPLADFASGLERLESRKVFGKILVTL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]