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The map label for this gene is iorA [H]

Identifier: 218532866

GI number: 218532866

Start: 5334210

End: 5334695

Strand: Reverse

Name: iorA [H]

Synonym: Mchl_4989

Alternate gene names: 218532866

Gene position: 5334695-5334210 (Counterclockwise)

Preceding gene: 218532867

Following gene: 218532865

Centisome position: 92.33

GC content: 66.87

Gene sequence:

>486_bases
ATGACAGCGATGATAAAACTCACGGTCAACGGAGCCGAACGCAGCTTCGACGGCGATCCCGAAATGCCGTTGCTCTGGTA
CCTGCGCGACGAACTTGGCCTCACCGGCACCAAGTTCGGCTGCGGCATCGCCCAGTGCGGCGCCTGCACGGTCCATCTCG
GCGGAACCGCCGCGCGGGCCTGCATCACCCCCGTCTCCGCGGCGGAAGGCCAGGAGATCACGACGATCGAGGGGCTCTCG
CCCGACGGCAACCACCCGGTTCAGGTGGCGTGGCGCGACCTCAACGTCGCCCAGTGCGGCTACTGCCAGACCGGTCAGAT
CATGCAGGCGGCGTCCCTCCTCAAGGACAGCCCGAAGCCGACCGACCAGCAGATCGACGAGAACATGAGCGGCAACATCT
GCCGCTGCGGCACCTATCCACGCATCCGCGCCGCGATCCATCAGGCTGCCGGTCAGGCGCCCGCCACCAAGGGAGATCGC
CTGTGA

Upstream 100 bases:

>100_bases
TTCGGGCCGGTCCCGTACGGCATCCCTGGGGACGGCAGATCGATCTGGCCGCCGGGCGGGCATTCCTTCCGCTCGCGCGC
CCTCCATCCTGAAACGGCAG

Downstream 100 bases:

>100_bases
TTCACGAAGCCAAGCTGATGGTCGAACTCGCCGCCTCGCAGAACGCCGCCGGCCCGGTCCGGATCGACAATGTCAGCCGC
CGCGGCATCCTCGGCGGCAT

Product: (2Fe-2S)-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTAMIKLTVNGAERSFDGDPEMPLLWYLRDELGLTGTKFGCGIAQCGACTVHLGGTAARACITPVSAAEGQEITTIEGLS
PDGNHPVQVAWRDLNVAQCGYCQTGQIMQAASLLKDSPKPTDQQIDENMSGNICRCGTYPRIRAAIHQAAGQAPATKGDR
L

Sequences:

>Translated_161_residues
MTAMIKLTVNGAERSFDGDPEMPLLWYLRDELGLTGTKFGCGIAQCGACTVHLGGTAARACITPVSAAEGQEITTIEGLS
PDGNHPVQVAWRDLNVAQCGYCQTGQIMQAASLLKDSPKPTDQQIDENMSGNICRCGTYPRIRAAIHQAAGQAPATKGDR
L
>Mature_160_residues
TAMIKLTVNGAERSFDGDPEMPLLWYLRDELGLTGTKFGCGIAQCGACTVHLGGTAARACITPVSAAEGQEITTIEGLSP
DGNHPVQVAWRDLNVAQCGYCQTGQIMQAASLLKDSPKPTDQQIDENMSGNICRCGTYPRIRAAIHQAAGQAPATKGDRL

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=135, Percent_Identity=40, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI71773480, Length=133, Percent_Identity=36.0902255639098, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=45.1219512195122, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789232, Length=144, Percent_Identity=39.5833333333333, Blast_Score=91, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=38.0645161290323, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17540638, Length=145, Percent_Identity=38.6206896551724, Blast_Score=109, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI32566215, Length=161, Percent_Identity=36.6459627329193, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI17737937, Length=151, Percent_Identity=35.0993377483444, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=34.7826086956522, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=30.5194805194805, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17050; Mature: 16918

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAMIKLTVNGAERSFDGDPEMPLLWYLRDELGLTGTKFGCGIAQCGACTVHLGGTAARA
CCEEEEEEECCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCEEEEEECCCHHHH
CITPVSAAEGQEITTIEGLSPDGNHPVQVAWRDLNVAQCGYCQTGQIMQAASLLKDSPKP
HHCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
TDQQIDENMSGNICRCGTYPRIRAAIHQAAGQAPATKGDRL
CHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TAMIKLTVNGAERSFDGDPEMPLLWYLRDELGLTGTKFGCGIAQCGACTVHLGGTAARA
CEEEEEEECCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCEEEEEECCCHHHH
CITPVSAAEGQEITTIEGLSPDGNHPVQVAWRDLNVAQCGYCQTGQIMQAASLLKDSPKP
HHCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
TDQQIDENMSGNICRCGTYPRIRAAIHQAAGQAPATKGDRL
CHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]