| Definition | Methylobacterium chloromethanicum CM4, complete genome. |
|---|---|
| Accession | NC_011757 |
| Length | 5,777,908 |
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The map label for this gene is xdhA [C]
Identifier: 218532865
GI number: 218532865
Start: 5331862
End: 5334213
Strand: Reverse
Name: xdhA [C]
Synonym: Mchl_4988
Alternate gene names: 218532865
Gene position: 5334213-5331862 (Counterclockwise)
Preceding gene: 218532866
Following gene: 218532864
Centisome position: 92.32
GC content: 68.79
Gene sequence:
>2352_bases GTGATTCACGAAGCCAAGCTGATGGTCGAACTCGCCGCCTCGCAGAACGCCGCCGGCCCGGTCCGGATCGACAATGTCAG CCGCCGCGGCATCCTCGGCGGCATGGGCGCCCTCGTGCTCGCCCTCTCGCTCTCGGACCGTGCCAAGGCCGACGAGGGCC AGACCGAGGAGCAGAAGGCGAAGAAGTTCGGCGCCGACGGCATGCCGAACGGCTGGCGCGACGATCCGAAGGTCTTCGTC GCGATCGCCAAGGACGGCACCGTCACCGTCACCAACCACCGCTCCGAGATGGGCCAGGGCGTTCGCACCTCGATCGCCTT CACCGTCGCCGACGAGCTGGAGGCCGATTGGTCGAAGGTGAAAGTGGTCCAGGCCTGGGGTGAGGAGACTCATTTCGGCA ACCAGGACACCGACGGCTCGCGCTCGCTCCGCCACTTCTTCCAGCATTTCCGCCATGCGGGTGCGTCCGCGCGGCTGATG CTGATCCAGGCCGCCGCCAAGCAATGGGGCGTGCCGGCCGGTGAAGTGAAGGCCGAGAACCACGTCCTGACCCACGCCAA GTCGGGCCGTACGCTGGGCTACGGTGACGTCGCCGAGGCGGCCGCCGCCCTGCCGGTGCCGGCCCGCGAGAGCGTTCAGC TCAAGAAGCCGGAGGCCTTCCGCTACATCGGCAAGGGCAAGATCGGCCTGATCGACAACCACGACATCACCACCGGCAAG GCGATCTACGCCCTCGACGTGAAGCTCGACGGCATGCTCTACGCCCTCGTCGCGCGTCCGGCCGTCTACGGCGGCAAGGT CGTCTCGTTCGACGACACCGAGGCCAAGAAGGTCCCGGGCGTGGTCAAGATCATCAAGATCGAGGGCGGCGAGATCCCGT CCGAGTTCATGCCGCTGGGCGGCATCGCGGTGATCGCCAAGAACACCTGGGCGGCGATGAAGGGCCGCGAGGCCCTGAAG ATCACCTGGGATGACGGCCCGAACGCGTCCTACGACACCACCGCCTTCCGCAAGGAACTGGAGAAGGCCGCCCGTGCGCC GGGCAAGGTCGTGCGGGTCGCAGGCGACGTCGATGGCGCGATGAAGACCGCCAAGGCGAAGTTCGAGGCGGAGTACTTCG TGCCCCACCTCGCCCAGGCGCCGATGGAGCCGCCGGCCGCGGTCGCCCGCATCAAGGACGGCGCCTGCGAGATCTGGGCC TGCACGCAGGGGCCGCAGGCCGCCCATGACCGAGTGGTGAAGCGCCTCAACCTGCCCGCCGACAAGGTGCGGGTGAACGT GACACTGCTCGGCGGCGGGTTCGGCCGCAAGTCGAAGCCCGACTACGTGGTCGAGGCCGCCCTCTGCTCGCAGGCCATGG ACGGCCAGCCGGTCAAGCTGGTCTGGACCCGCGAGGACGACATCCAGCACAGCTACTACCACACCATCTCGGTCGAGCGG ATCGAGGCGGGCGTTGACGAGAAGGGCATGCCGGTGGCGTGGCTCCACCGCTCGGTGGCGCCGACGATCGGCTCGATCTT CGCGCCCGACCCGAAGCACGAGCTGCCATTCGAGCTCGGCATGGGCCTCGTCAACAACCCGCTGGCGCTGAAGAACCTGC GGTTCGAGAACCCGGAAGCCTCCGCCCATACCCGGATCGGCTGGTTCCGCTCGGTCTCGAACATCCCGCACGCCTTCGCG ATCCAGTCCTTCGTGGCCGAACTCGCGCACGCGGCGGGCCGCGACCCGAAGGACTACCTGCTGGAGCTGATCGGCCCCGC CCGGAAGATCGACCCGACCGAGATCGGCGACGTCTGGAACTACGGCGAGGATCCGAAGCGCTACCCCGTCGATACCGGCC GCCTGCGCCGCGTCATCGAGACGGTGGCCGACGGCGCCAAGTGGGGCCGCAAGCTGGAGAAGGGCCGGGGGCTCGGCATC GCCGGCCACTACAGCTTCGTGACCTACACCGCGGTCGCGGCCGAGGTGGAGGTCGATGACAAGGGCCAGGTGAAGGTCCA CGCCATCGACATCGCCGTCGATTGCGGGCCGCAGGTGAACCCGGAGCGCGTCCGCTCGCAGATGGAGGGCGCGGTGGTCA TGGGGATGGGCCTCGCCCTCACCTCGAAGATCACCTTCAAGAACGGCCGGGCCGAGCAGTCCAACTACGACGGCTACGAG GTTCTGCGCATCGACGCCGCCCCGAAGGTGGTGCGGGTGCATCTCGTGCCGTCCAACAACTACGACAGCCCGCTCGGCGG CGTCGGCGAGCCGGGTGTTCCCCCGGTCGCGCCGGCCATCGCCAACGCGGTCTTCGCCGCCACCGGACGCCGGGTGCGCG AGCTGCCGCTGCGCGACCAGCTCAGCACCTGA
Upstream 100 bases:
>100_bases ACATGAGCGGCAACATCTGCCGCTGCGGCACCTATCCACGCATCCGCGCCGCGATCCATCAGGCTGCCGGTCAGGCGCCC GCCACCAAGGGAGATCGCCT
Downstream 100 bases:
>100_bases GGTCGCCGGCCGACGCCCTTCCCCTTCGCCGGGGGAGGGCGCCGTCCGAAGGTCGAGGGGACGAGGATCGGCCGTGCCGG CAACTCTCGGACCCCTCCGC
Product: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding
Products: NA
Alternate protein names: ALDH [H]
Number of amino acids: Translated: 783; Mature: 783
Protein sequence:
>783_residues MIHEAKLMVELAASQNAAGPVRIDNVSRRGILGGMGALVLALSLSDRAKADEGQTEEQKAKKFGADGMPNGWRDDPKVFV AIAKDGTVTVTNHRSEMGQGVRTSIAFTVADELEADWSKVKVVQAWGEETHFGNQDTDGSRSLRHFFQHFRHAGASARLM LIQAAAKQWGVPAGEVKAENHVLTHAKSGRTLGYGDVAEAAAALPVPARESVQLKKPEAFRYIGKGKIGLIDNHDITTGK AIYALDVKLDGMLYALVARPAVYGGKVVSFDDTEAKKVPGVVKIIKIEGGEIPSEFMPLGGIAVIAKNTWAAMKGREALK ITWDDGPNASYDTTAFRKELEKAARAPGKVVRVAGDVDGAMKTAKAKFEAEYFVPHLAQAPMEPPAAVARIKDGACEIWA CTQGPQAAHDRVVKRLNLPADKVRVNVTLLGGGFGRKSKPDYVVEAALCSQAMDGQPVKLVWTREDDIQHSYYHTISVER IEAGVDEKGMPVAWLHRSVAPTIGSIFAPDPKHELPFELGMGLVNNPLALKNLRFENPEASAHTRIGWFRSVSNIPHAFA IQSFVAELAHAAGRDPKDYLLELIGPARKIDPTEIGDVWNYGEDPKRYPVDTGRLRRVIETVADGAKWGRKLEKGRGLGI AGHYSFVTYTAVAAEVEVDDKGQVKVHAIDIAVDCGPQVNPERVRSQMEGAVVMGMGLALTSKITFKNGRAEQSNYDGYE VLRIDAAPKVVRVHLVPSNNYDSPLGGVGEPGVPPVAPAIANAVFAATGRRVRELPLRDQLST
Sequences:
>Translated_783_residues MIHEAKLMVELAASQNAAGPVRIDNVSRRGILGGMGALVLALSLSDRAKADEGQTEEQKAKKFGADGMPNGWRDDPKVFV AIAKDGTVTVTNHRSEMGQGVRTSIAFTVADELEADWSKVKVVQAWGEETHFGNQDTDGSRSLRHFFQHFRHAGASARLM LIQAAAKQWGVPAGEVKAENHVLTHAKSGRTLGYGDVAEAAAALPVPARESVQLKKPEAFRYIGKGKIGLIDNHDITTGK AIYALDVKLDGMLYALVARPAVYGGKVVSFDDTEAKKVPGVVKIIKIEGGEIPSEFMPLGGIAVIAKNTWAAMKGREALK ITWDDGPNASYDTTAFRKELEKAARAPGKVVRVAGDVDGAMKTAKAKFEAEYFVPHLAQAPMEPPAAVARIKDGACEIWA CTQGPQAAHDRVVKRLNLPADKVRVNVTLLGGGFGRKSKPDYVVEAALCSQAMDGQPVKLVWTREDDIQHSYYHTISVER IEAGVDEKGMPVAWLHRSVAPTIGSIFAPDPKHELPFELGMGLVNNPLALKNLRFENPEASAHTRIGWFRSVSNIPHAFA IQSFVAELAHAAGRDPKDYLLELIGPARKIDPTEIGDVWNYGEDPKRYPVDTGRLRRVIETVADGAKWGRKLEKGRGLGI AGHYSFVTYTAVAAEVEVDDKGQVKVHAIDIAVDCGPQVNPERVRSQMEGAVVMGMGLALTSKITFKNGRAEQSNYDGYE VLRIDAAPKVVRVHLVPSNNYDSPLGGVGEPGVPPVAPAIANAVFAATGRRVRELPLRDQLST >Mature_783_residues MIHEAKLMVELAASQNAAGPVRIDNVSRRGILGGMGALVLALSLSDRAKADEGQTEEQKAKKFGADGMPNGWRDDPKVFV AIAKDGTVTVTNHRSEMGQGVRTSIAFTVADELEADWSKVKVVQAWGEETHFGNQDTDGSRSLRHFFQHFRHAGASARLM LIQAAAKQWGVPAGEVKAENHVLTHAKSGRTLGYGDVAEAAAALPVPARESVQLKKPEAFRYIGKGKIGLIDNHDITTGK AIYALDVKLDGMLYALVARPAVYGGKVVSFDDTEAKKVPGVVKIIKIEGGEIPSEFMPLGGIAVIAKNTWAAMKGREALK ITWDDGPNASYDTTAFRKELEKAARAPGKVVRVAGDVDGAMKTAKAKFEAEYFVPHLAQAPMEPPAAVARIKDGACEIWA CTQGPQAAHDRVVKRLNLPADKVRVNVTLLGGGFGRKSKPDYVVEAALCSQAMDGQPVKLVWTREDDIQHSYYHTISVER IEAGVDEKGMPVAWLHRSVAPTIGSIFAPDPKHELPFELGMGLVNNPLALKNLRFENPEASAHTRIGWFRSVSNIPHAFA IQSFVAELAHAAGRDPKDYLLELIGPARKIDPTEIGDVWNYGEDPKRYPVDTGRLRRVIETVADGAKWGRKLEKGRGLGI AGHYSFVTYTAVAAEVEVDDKGQVKVHAIDIAVDCGPQVNPERVRSQMEGAVVMGMGLALTSKITFKNGRAEQSNYDGYE VLRIDAAPKVVRVHLVPSNNYDSPLGGVGEPGVPPVAPAIANAVFAATGRRVRELPLRDQLST
Specific function: Presumed To Be A Dehydrogenase, But Possibly An Oxidase. Participates In Limited Purine Salvage (Requires Aspartate) But Does Not Support Aerobic Growth On Purines As The Sole Carbon Source (Purine Catabolism). Deletion Results In Increased Adenine Sensit
COG id: COG1529
COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1786478, Length=143, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=7e-13, Organism=Escherichia coli, GI1789246, Length=156, Percent_Identity=32.6923076923077, Blast_Score=65, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000674 - InterPro: IPR008274 - InterPro: IPR012368 - InterPro: IPR006311 [H]
Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]
EC number: =1.2.99.3 [H]
Molecular weight: Translated: 84628; Mature: 84628
Theoretical pI: Translated: 8.51; Mature: 8.51
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIHEAKLMVELAASQNAAGPVRIDNVSRRGILGGMGALVLALSLSDRAKADEGQTEEQKA CCCHHEEHEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCHHHHH KKFGADGMPNGWRDDPKVFVAIAKDGTVTVTNHRSEMGQGVRTSIAFTVADELEADWSKV HHCCCCCCCCCCCCCCEEEEEEECCCEEEEECCHHHHCCCCEEEEEEEEHHHHHCCHHHE KVVQAWGEETHFGNQDTDGSRSLRHFFQHFRHAGASARLMLIQAAAKQWGVPAGEVKAEN EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHEEHHHHHHCCCCCCCCCCC HVLTHAKSGRTLGYGDVAEAAAALPVPARESVQLKKPEAFRYIGKGKIGLIDNHDITTGK EEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCEECCCHHHHEECCCCEEEEECCCCCCCC AIYALDVKLDGMLYALVARPAVYGGKVVSFDDTEAKKVPGVVKIIKIEGGEIPSEFMPLG EEEEEEEEECCCCEEEHHCCHHCCCEEEEECCCCHHHCCCEEEEEEECCCCCCHHHCCCC GIAVIAKNTWAAMKGREALKITWDDGPNASYDTTAFRKELEKAARAPGKVVRVAGDVDGA CEEEEECCCHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHH MKTAKAKFEAEYFVPHLAQAPMEPPAAVARIKDGACEIWACTQGPQAAHDRVVKRLNLPA HHHHHHHHCHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCH DKVRVNVTLLGGGFGRKSKPDYVVEAALCSQAMDGQPVKLVWTREDDIQHSYYHTISVER HHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEH IEAGVDEKGMPVAWLHRSVAPTIGSIFAPDPKHELPFELGMGLVNNPLALKNLRFENPEA HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCEEECCCCCCCCCC SAHTRIGWFRSVSNIPHAFAIQSFVAELAHAAGRDPKDYLLELIGPARKIDPTEIGDVWN CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHCHHCC YGEDPKRYPVDTGRLRRVIETVADGAKWGRKLEKGRGLGIAGHYSFVTYTAVAAEVEVDD CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHEEEEEEEEEEEECC KGQVKVHAIDIAVDCGPQVNPERVRSQMEGAVVMGMGLALTSKITFKNGRAEQSNYDGYE CCCEEEEEEEEEEECCCCCCHHHHHHHHCCEEEEECCEEEEEEEEECCCCCCCCCCCCEE VLRIDAAPKVVRVHLVPSNNYDSPLGGVGEPGVPPVAPAIANAVFAATGRRVRELPLRDQ EEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCHHC LST CCC >Mature Secondary Structure MIHEAKLMVELAASQNAAGPVRIDNVSRRGILGGMGALVLALSLSDRAKADEGQTEEQKA CCCHHEEHEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCHHHHH KKFGADGMPNGWRDDPKVFVAIAKDGTVTVTNHRSEMGQGVRTSIAFTVADELEADWSKV HHCCCCCCCCCCCCCCEEEEEEECCCEEEEECCHHHHCCCCEEEEEEEEHHHHHCCHHHE KVVQAWGEETHFGNQDTDGSRSLRHFFQHFRHAGASARLMLIQAAAKQWGVPAGEVKAEN EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHEEHHHHHHCCCCCCCCCCC HVLTHAKSGRTLGYGDVAEAAAALPVPARESVQLKKPEAFRYIGKGKIGLIDNHDITTGK EEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCEECCCHHHHEECCCCEEEEECCCCCCCC AIYALDVKLDGMLYALVARPAVYGGKVVSFDDTEAKKVPGVVKIIKIEGGEIPSEFMPLG EEEEEEEEECCCCEEEHHCCHHCCCEEEEECCCCHHHCCCEEEEEEECCCCCCHHHCCCC GIAVIAKNTWAAMKGREALKITWDDGPNASYDTTAFRKELEKAARAPGKVVRVAGDVDGA CEEEEECCCHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHH MKTAKAKFEAEYFVPHLAQAPMEPPAAVARIKDGACEIWACTQGPQAAHDRVVKRLNLPA HHHHHHHHCHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCH DKVRVNVTLLGGGFGRKSKPDYVVEAALCSQAMDGQPVKLVWTREDDIQHSYYHTISVER HHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEH IEAGVDEKGMPVAWLHRSVAPTIGSIFAPDPKHELPFELGMGLVNNPLALKNLRFENPEA HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCEEECCCCCCCCCC SAHTRIGWFRSVSNIPHAFAIQSFVAELAHAAGRDPKDYLLELIGPARKIDPTEIGDVWN CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHCHHCC YGEDPKRYPVDTGRLRRVIETVADGAKWGRKLEKGRGLGIAGHYSFVTYTAVAAEVEVDD CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHEEEEEEEEEEEECC KGQVKVHAIDIAVDCGPQVNPERVRSQMEGAVVMGMGLALTSKITFKNGRAEQSNYDGYE CCCEEEEEEEEEEECCCCCCHHHHHHHHCCEEEEECCEEEEEEEEECCCCCCCCCCCCEE VLRIDAAPKVVRVHLVPSNNYDSPLGGVGEPGVPPVAPAIANAVFAATGRRVRELPLRDQ EEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCHHC LST CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 2606906 [H]