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The map label for this gene is nahR [H]

Identifier: 218532855

GI number: 218532855

Start: 5320604

End: 5321563

Strand: Reverse

Name: nahR [H]

Synonym: Mchl_4978

Alternate gene names: 218532855

Gene position: 5321563-5320604 (Counterclockwise)

Preceding gene: 218532857

Following gene: 218532854

Centisome position: 92.1

GC content: 67.29

Gene sequence:

>960_bases
ATGCGCATCGATCACGTGCATCTTTCCCGGCTCGATCTCAACCTGCTCGTCGCCCTCGACGCGCTGCTGACGGAGCGGAG
CGTGACCCGCGCGGCCGGACGGATCGGCATCAGCCAGTCGGCGATGAGCCATGCCCTGGCGCGACTGCGCACCGCCTTCT
CGGATGAGCTGCTGACGCGGGGCCCCGACGGCATGCGGCCGACGCCGCGCGCGCTGGCGCTCCTTGGGCCGGTACAGGCG
GCACTCTCCCAGATTCAGGAGATCACGACGCCGCCGGCTGCCTTCGATCCGGCCACGGCCGACCTCACCTTCACCCTCGG
CATCCCGGACTCGACCGAGGTGCTCCTGATGCCGACCCTCATCGCGCATCTCCAGGCGGTGGCACCGGGGGTGAAGCTTC
TGCTGCACACGGTCGATCGGCATCGCATCCTCGACGACCTCGATACGGGGCGGGTCGATCTCGGCATCGGCGTGTTCGAG
CAGGGCCAGACGCATCACAAGCGACGGATTCTCAACAAGGAGAGCTACCTCTGCATCTTCAACGCCGAGCTGGTCGGGGT
GACGGCGCCGATTTCGCTCGACGACTACGTGCGGCTCCCGCACCTGCTCACGAGCTTGGTCGAGAGCGCCCACGGCGTGG
TGGACGACGCGCTGGCCAAGATCGGCCGCAAGCGCGTCATCGCGCTGACCTCGCCGCGGTTCTCGGTGATGCCCTTCGTG
GTGCGACAGGCCCCCGTCATCGCCACGATGCACGCCCGGCTCGCGCGCTTCTTCGCCGACAGCATGGGCCTGACCGTCAG
CCCGGCACCGATCACACTGCCGGACGTCTCCATCTCGATGATCTGGCACACGTCCAACGACGCCATTCCCAGTCAGCGCT
GGCTGCGGGAGACCATCATAAAGCTACGCAAATCCGATCCCCGGCCGCCGACCGACGGCTCTCACACGACATCCGATTGA

Upstream 100 bases:

>100_bases
ACATCGAGATCAGCCTCTTTTCGTGCGGCGGGCTCCCCGTCGCTTCGTGAGACTGTATGTGCTGGGTCATGGCCCATGAA
TCAAATGGATCGATTTCATA

Downstream 100 bases:

>100_bases
TCCCTACGGGATGTCGGCGTCGCTCAAGCGCCGTAGGCTTCCCGCATCAGCCGTGGATCAGCATCATCGCTACATCAACG
GCTTGAAGGCGGTTGCCTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRIDHVHLSRLDLNLLVALDALLTERSVTRAAGRIGISQSAMSHALARLRTAFSDELLTRGPDGMRPTPRALALLGPVQA
ALSQIQEITTPPAAFDPATADLTFTLGIPDSTEVLLMPTLIAHLQAVAPGVKLLLHTVDRHRILDDLDTGRVDLGIGVFE
QGQTHHKRRILNKESYLCIFNAELVGVTAPISLDDYVRLPHLLTSLVESAHGVVDDALAKIGRKRVIALTSPRFSVMPFV
VRQAPVIATMHARLARFFADSMGLTVSPAPITLPDVSISMIWHTSNDAIPSQRWLRETIIKLRKSDPRPPTDGSHTTSD

Sequences:

>Translated_319_residues
MRIDHVHLSRLDLNLLVALDALLTERSVTRAAGRIGISQSAMSHALARLRTAFSDELLTRGPDGMRPTPRALALLGPVQA
ALSQIQEITTPPAAFDPATADLTFTLGIPDSTEVLLMPTLIAHLQAVAPGVKLLLHTVDRHRILDDLDTGRVDLGIGVFE
QGQTHHKRRILNKESYLCIFNAELVGVTAPISLDDYVRLPHLLTSLVESAHGVVDDALAKIGRKRVIALTSPRFSVMPFV
VRQAPVIATMHARLARFFADSMGLTVSPAPITLPDVSISMIWHTSNDAIPSQRWLRETIIKLRKSDPRPPTDGSHTTSD
>Mature_319_residues
MRIDHVHLSRLDLNLLVALDALLTERSVTRAAGRIGISQSAMSHALARLRTAFSDELLTRGPDGMRPTPRALALLGPVQA
ALSQIQEITTPPAAFDPATADLTFTLGIPDSTEVLLMPTLIAHLQAVAPGVKLLLHTVDRHRILDDLDTGRVDLGIGVFE
QGQTHHKRRILNKESYLCIFNAELVGVTAPISLDDYVRLPHLLTSLVESAHGVVDDALAKIGRKRVIALTSPRFSVMPFV
VRQAPVIATMHARLARFFADSMGLTVSPAPITLPDVSISMIWHTSNDAIPSQRWLRETIIKLRKSDPRPPTDGSHTTSD

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=298, Percent_Identity=26.1744966442953, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790147, Length=305, Percent_Identity=26.5573770491803, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34832; Mature: 34832

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDHVHLSRLDLNLLVALDALLTERSVTRAAGRIGISQSAMSHALARLRTAFSDELLTR
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
GPDGMRPTPRALALLGPVQAALSQIQEITTPPAAFDPATADLTFTLGIPDSTEVLLMPTL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHH
IAHLQAVAPGVKLLLHTVDRHRILDDLDTGRVDLGIGVFEQGQTHHKRRILNKESYLCIF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHCCCCCEEEEE
NAELVGVTAPISLDDYVRLPHLLTSLVESAHGVVDDALAKIGRKRVIALTSPRFSVMPFV
ECEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCHHHHHHH
VRQAPVIATMHARLARFFADSMGLTVSPAPITLPDVSISMIWHTSNDAIPSQRWLRETII
HHCCCHHHHHHHHHHHHHHHHCCCEECCCCEEECCCEEEEEEECCCCCCCHHHHHHHHHH
KLRKSDPRPPTDGSHTTSD
HHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIDHVHLSRLDLNLLVALDALLTERSVTRAAGRIGISQSAMSHALARLRTAFSDELLTR
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
GPDGMRPTPRALALLGPVQAALSQIQEITTPPAAFDPATADLTFTLGIPDSTEVLLMPTL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHH
IAHLQAVAPGVKLLLHTVDRHRILDDLDTGRVDLGIGVFEQGQTHHKRRILNKESYLCIF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHCCCCCEEEEE
NAELVGVTAPISLDDYVRLPHLLTSLVESAHGVVDDALAKIGRKRVIALTSPRFSVMPFV
ECEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCHHHHHHH
VRQAPVIATMHARLARFFADSMGLTVSPAPITLPDVSISMIWHTSNDAIPSQRWLRETII
HHCCCHHHHHHHHHHHHHHHHCCCEECCCCEEECCCEEEEEEECCCCCCCHHHHHHHHHH
KLRKSDPRPPTDGSHTTSD
HHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]