Click here to switch to the map view.

The map label for this gene is accD

Identifier: 218532786

GI number: 218532786

Start: 5231046

End: 5231969

Strand: Reverse

Name: accD

Synonym: Mchl_4909

Alternate gene names: 218532786

Gene position: 5231969-5231046 (Counterclockwise)

Preceding gene: 218532787

Following gene: 218532785

Centisome position: 90.55

GC content: 68.29

Gene sequence:

>924_bases
ATGGTCGAGCCGATGAACTGGATCTCGGAGGTCGTACGGCCCCGGATCAAGACGCTGTTCAAGCGCGAGACGCCGGAGAA
CCTCTGGGTCAAGTGCCCCGACACGGGCCAGATGGTCTTCCATAAGGAAGTCGAGCAGAACCACTGGGTCATTCCCGGCT
CCGAACACCATCTCAAGATGTCGGCCACGGCGCGTCTCAAGATGATGTTCGACGAGGGCACCTGGATCGACGTGCCGCTG
CCCGAGGTGCCGGCCGACCCGCTCAAGTTCCGCGACGAGAAGCGCTACGTCGACCGTCTCAAGGAGGCGCGGGCCAAGAC
CGGGATGCCCGACGCGTTCAAGATCGGCTTCGGCCGGGTCGGCAGCCTGCCGATGACGATCGCGGCTCAGGAATTCGGCT
TCATGGCCGGCTCCCTCGGCATGGCCGGCGGCGAGGCCTTCGTCCGCGGCGCCGAGACGGCGCTCGAGAAGCGCACCCCC
TACGTGCTGTTCGCGGCCTCCGGCGGGGCGCGGATGCAGGAGGGGATCCTCTCGCTTATGCAGATGCCCCGCACCACGGT
CGCCGTGCGCCGGCTCCGGGCCGCGCGGCTGCCCTATATCGTGGTGCTGACCAACCCGACCACCGGCGGCGTCACCGCCT
CCTACGCCATGCTCGGCGACGTGCATCTGGCCGAGCCCGGCGCGCTGATCTGCTTTGCCGGCCCGCGCGTCATCGAGCAG
ACCATCCGCGAGAAGCTGCCCGACGGCTTCCAGCGGGCGGAGTATCTGCGCGAGCACGGCATGGTCGATCAGGTCGTCCA
CCGGCATCAGCTCAAGGAAACGATCAGCCGGCTCTGCGGCTTGCTGATGGACGTGCGCCGGACGCCCCAACCCGGTACCG
CCCCCGAGCCGACCACACCCGAACCCCTGCCGAACGCGGCCTGA

Upstream 100 bases:

>100_bases
TCAGCAGGGAGATCCCCTGGGATCGAGGCGGCGGCGATCCGATATCGATGTGGCAAGGGAACGCGGCAAGTGAACGCGCT
GGGACAGGGAGTCTGACGCC

Downstream 100 bases:

>100_bases
ACTCAATCCGCGACAGAAGGTCTCCGCGCGAGATGGAATCCTCCGACGCGTTGATGGCGCGCTTCCTCGCCCTGCATCCG
CGCACGATCGACCTGTCGCT

Product: acetyl-CoA carboxylase, carboxyl transferase, beta subunit

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MVEPMNWISEVVRPRIKTLFKRETPENLWVKCPDTGQMVFHKEVEQNHWVIPGSEHHLKMSATARLKMMFDEGTWIDVPL
PEVPADPLKFRDEKRYVDRLKEARAKTGMPDAFKIGFGRVGSLPMTIAAQEFGFMAGSLGMAGGEAFVRGAETALEKRTP
YVLFAASGGARMQEGILSLMQMPRTTVAVRRLRAARLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGALICFAGPRVIEQ
TIREKLPDGFQRAEYLREHGMVDQVVHRHQLKETISRLCGLLMDVRRTPQPGTAPEPTTPEPLPNAA

Sequences:

>Translated_307_residues
MVEPMNWISEVVRPRIKTLFKRETPENLWVKCPDTGQMVFHKEVEQNHWVIPGSEHHLKMSATARLKMMFDEGTWIDVPL
PEVPADPLKFRDEKRYVDRLKEARAKTGMPDAFKIGFGRVGSLPMTIAAQEFGFMAGSLGMAGGEAFVRGAETALEKRTP
YVLFAASGGARMQEGILSLMQMPRTTVAVRRLRAARLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGALICFAGPRVIEQ
TIREKLPDGFQRAEYLREHGMVDQVVHRHQLKETISRLCGLLMDVRRTPQPGTAPEPTTPEPLPNAA
>Mature_307_residues
MVEPMNWISEVVRPRIKTLFKRETPENLWVKCPDTGQMVFHKEVEQNHWVIPGSEHHLKMSATARLKMMFDEGTWIDVPL
PEVPADPLKFRDEKRYVDRLKEARAKTGMPDAFKIGFGRVGSLPMTIAAQEFGFMAGSLGMAGGEAFVRGAETALEKRTP
YVLFAASGGARMQEGILSLMQMPRTTVAVRRLRAARLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGALICFAGPRVIEQ
TIREKLPDGFQRAEYLREHGMVDQVVHRHQLKETISRLCGLLMDVRRTPQPGTAPEPTTPEPLPNAA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=301, Percent_Identity=46.1794019933555, Blast_Score=277, Evalue=7e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_METC4 (B7KSK6)

Other databases:

- EMBL:   CP001298
- RefSeq:   YP_002423602.1
- ProteinModelPortal:   B7KSK6
- SMR:   B7KSK6
- GeneID:   7114330
- GenomeReviews:   CP001298_GR
- KEGG:   mch:Mchl_4909
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   CLSK2332180
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 34197; Mature: 34197

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEPMNWISEVVRPRIKTLFKRETPENLWVKCPDTGQMVFHKEVEQNHWVIPGSEHHLKM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEHHHHCCCCEECCCCCCEEEE
SATARLKMMFDEGTWIDVPLPEVPADPLKFRDEKRYVDRLKEARAKTGMPDAFKIGFGRV
ECCEEEEEEECCCCEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHCCCCCCEEECCCCC
GSLPMTIAAQEFGFMAGSLGMAGGEAFVRGAETALEKRTPYVLFAASGGARMQEGILSLM
CCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
QMPRTTVAVRRLRAARLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGALICFAGPRVIEQ
HCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEHHHHHCCEEECCCCEEEEECCHHHHHH
TIREKLPDGFQRAEYLREHGMVDQVVHRHQLKETISRLCGLLMDVRRTPQPGTAPEPTTP
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EPLPNAA
CCCCCCC
>Mature Secondary Structure
MVEPMNWISEVVRPRIKTLFKRETPENLWVKCPDTGQMVFHKEVEQNHWVIPGSEHHLKM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEHHHHCCCCEECCCCCCEEEE
SATARLKMMFDEGTWIDVPLPEVPADPLKFRDEKRYVDRLKEARAKTGMPDAFKIGFGRV
ECCEEEEEEECCCCEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHCCCCCCEEECCCCC
GSLPMTIAAQEFGFMAGSLGMAGGEAFVRGAETALEKRTPYVLFAASGGARMQEGILSLM
CCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
QMPRTTVAVRRLRAARLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGALICFAGPRVIEQ
HCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEHHHHHCCEEECCCCEEEEECCHHHHHH
TIREKLPDGFQRAEYLREHGMVDQVVHRHQLKETISRLCGLLMDVRRTPQPGTAPEPTTP
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EPLPNAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA