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The map label for this gene is yliI [H]

Identifier: 218532782

GI number: 218532782

Start: 5226269

End: 5227555

Strand: Reverse

Name: yliI [H]

Synonym: Mchl_4905

Alternate gene names: 218532782

Gene position: 5227555-5226269 (Counterclockwise)

Preceding gene: 218532784

Following gene: 218532779

Centisome position: 90.47

GC content: 68.45

Gene sequence:

>1287_bases
GTGACGCGCACCCTTTCCCTCTTGCTCGCCACCGTTGCGGCCCTCGGCCTCGATGCCCCAGCCTTCGCTCAGCAGCCGGC
CGGACAGGAGTCGCGCTCGCCCCGCATCGAGGGTGAGTCCTTCCAGGCGCCGGCCGCGCCGAGTGCCGGCACATCGATCG
CCGAGAAGGAAGCGCCGAACACTGAGTACAAGCCGCTCCTGCCCAACCAGACCCGTGCGCCGGAGCCCGCGCAGAAGACC
GAGTTCGAGACCGCCGTCGTGGCCAAGGGCCTGGAAAGCCCCTGGGCGATGGAGTTCCTGCCCGACGGCCGCATGATCGT
GACCGAGAAGGCCGGCAAGATCCGCCTGATCGCCAAGGACGGCACGGTGGGCCAGCCGGTGGCGGGCGTGCCGAAGGTCG
ATTCCAAGGGGCAGGGCGGTCTTCTCGACGTCGCGCTGAGCCCGAGCTTCGCCGCGGATCGCACGATCTACTTCAGCTAC
AGCGAGCCGCGCGACAAGGGCAACGGCACCACCGTCGCCAAGGCCAAGCTGGTCGAGAGCGACGGCAAGGCCAAGCTCGA
CGACGTCAAGGTCATCTTCCGCCAGATGCCGACCTATGACGGCGACAAGCATTTCGGCTCGCGCCTCGTCTTCGCGCCGG
ACGGCAAGCTGTTCGTCACCGTGGGCGAGCGCTCCGACAAGCAGACCCGCGGGCAGGCGCAGGATCTGACGAGCGGGCTC
GGCAAGGTCTTCCGCATCGACACCGACGGCAACGCCCCGAAGGACAACCCCTTCACCGGCGGCGAGAAGGCCAAGCCCGA
GATCTGGTCCTACGGCCACCGCAACGTTCAGGCCGCCGCCCTGGACAACCAGGGCCGGCTCTGGACCGTGGAGCACGGGC
CCCGCGGCGGCGACGAGCTGAACCGCCCGCGCCCCGGCCTCAACTACGGCTGGCCGGTGGTCACTTACGGCATCGAATAT
TCCGGCGAGAAGATCGGCGACGGCCAGACCCAGGCCGGCGGCACGGTGCAGCCGGTCTATTACTGGGATCCGGTGATCGG
CCCCTCGGGCATGGCGCTCTACGACAAGGACGCGTTCCCGGCCTGGAAGAACCAGTTCCTTATCGGCGGCCTCGTCAGCA
CCGGGATCGTTGCGGTCAAGCTCGACGGCGACAAGGTCGTCACCGAGGAGCGTATCCCGCTGGAACACCGCGTCCGCGAC
GTGCGGGTCGGCCCCGATGGTGCCGTCTACGCGGTGACCGAGGATGACGGCCAGATCGTCAAGCTGACGCCGAAGAAGGG
CAGCTGA

Upstream 100 bases:

>100_bases
CGTGGCGAGTCCGCCTCCTCGCGCGGCCCAACCCTCGCCGTGGGCCACCTGCGCCCCATTTGGCGAGCAAGATCGGCGAC
CCGCACAAGGATCAATCGAC

Downstream 100 bases:

>100_bases
GGAAGACGGAACGGGCCTCGCGGGGGGCTCCCCCCTCTCCCCGCTGTGCGGGGGGAGGGACTGTGCGTCTCATGGTGCTC
GATCATCGGGCAGCGCTCAT

Product: glucose sorbosone dehydrogenase

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTRTLSLLLATVAALGLDAPAFAQQPAGQESRSPRIEGESFQAPAAPSAGTSIAEKEAPNTEYKPLLPNQTRAPEPAQKT
EFETAVVAKGLESPWAMEFLPDGRMIVTEKAGKIRLIAKDGTVGQPVAGVPKVDSKGQGGLLDVALSPSFAADRTIYFSY
SEPRDKGNGTTVAKAKLVESDGKAKLDDVKVIFRQMPTYDGDKHFGSRLVFAPDGKLFVTVGERSDKQTRGQAQDLTSGL
GKVFRIDTDGNAPKDNPFTGGEKAKPEIWSYGHRNVQAAALDNQGRLWTVEHGPRGGDELNRPRPGLNYGWPVVTYGIEY
SGEKIGDGQTQAGGTVQPVYYWDPVIGPSGMALYDKDAFPAWKNQFLIGGLVSTGIVAVKLDGDKVVTEERIPLEHRVRD
VRVGPDGAVYAVTEDDGQIVKLTPKKGS

Sequences:

>Translated_428_residues
MTRTLSLLLATVAALGLDAPAFAQQPAGQESRSPRIEGESFQAPAAPSAGTSIAEKEAPNTEYKPLLPNQTRAPEPAQKT
EFETAVVAKGLESPWAMEFLPDGRMIVTEKAGKIRLIAKDGTVGQPVAGVPKVDSKGQGGLLDVALSPSFAADRTIYFSY
SEPRDKGNGTTVAKAKLVESDGKAKLDDVKVIFRQMPTYDGDKHFGSRLVFAPDGKLFVTVGERSDKQTRGQAQDLTSGL
GKVFRIDTDGNAPKDNPFTGGEKAKPEIWSYGHRNVQAAALDNQGRLWTVEHGPRGGDELNRPRPGLNYGWPVVTYGIEY
SGEKIGDGQTQAGGTVQPVYYWDPVIGPSGMALYDKDAFPAWKNQFLIGGLVSTGIVAVKLDGDKVVTEERIPLEHRVRD
VRVGPDGAVYAVTEDDGQIVKLTPKKGS
>Mature_427_residues
TRTLSLLLATVAALGLDAPAFAQQPAGQESRSPRIEGESFQAPAAPSAGTSIAEKEAPNTEYKPLLPNQTRAPEPAQKTE
FETAVVAKGLESPWAMEFLPDGRMIVTEKAGKIRLIAKDGTVGQPVAGVPKVDSKGQGGLLDVALSPSFAADRTIYFSYS
EPRDKGNGTTVAKAKLVESDGKAKLDDVKVIFRQMPTYDGDKHFGSRLVFAPDGKLFVTVGERSDKQTRGQAQDLTSGLG
KVFRIDTDGNAPKDNPFTGGEKAKPEIWSYGHRNVQAAALDNQGRLWTVEHGPRGGDELNRPRPGLNYGWPVVTYGIEYS
GEKIGDGQTQAGGTVQPVYYWDPVIGPSGMALYDKDAFPAWKNQFLIGGLVSTGIVAVKLDGDKVVTEERIPLEHRVRDV
RVGPDGAVYAVTEDDGQIVKLTPKKGS

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI187936955, Length=323, Percent_Identity=26.625386996904, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI187936953, Length=323, Percent_Identity=26.625386996904, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI124248546, Length=343, Percent_Identity=26.530612244898, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1787060, Length=348, Percent_Identity=44.5402298850575, Blast_Score=287, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 45947; Mature: 45816

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTLSLLLATVAALGLDAPAFAQQPAGQESRSPRIEGESFQAPAAPSAGTSIAEKEAPN
CCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCC
TEYKPLLPNQTRAPEPAQKTEFETAVVAKGLESPWAMEFLPDGRMIVTEKAGKIRLIAKD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCEEEEEEEC
GTVGQPVAGVPKVDSKGQGGLLDVALSPSFAADRTIYFSYSEPRDKGNGTTVAKAKLVES
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEEEECC
DGKAKLDDVKVIFRQMPTYDGDKHFGSRLVFAPDGKLFVTVGERSDKQTRGQAQDLTSGL
CCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCHHCCHHHHHHHCC
GKVFRIDTDGNAPKDNPFTGGEKAKPEIWSYGHRNVQAAALDNQGRLWTVEHGPRGGDEL
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCC
NRPRPGLNYGWPVVTYGIEYSGEKIGDGQTQAGGTVQPVYYWDPVIGPSGMALYDKDAFP
CCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCC
AWKNQFLIGGLVSTGIVAVKLDGDKVVTEERIPLEHRVRDVRVGPDGAVYAVTEDDGQIV
CHHCCEEEEEEHHCCEEEEEECCCEEEECCCCCHHHCCEEEEECCCCEEEEEECCCCEEE
KLTPKKGS
EEECCCCC
>Mature Secondary Structure 
TRTLSLLLATVAALGLDAPAFAQQPAGQESRSPRIEGESFQAPAAPSAGTSIAEKEAPN
CHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCC
TEYKPLLPNQTRAPEPAQKTEFETAVVAKGLESPWAMEFLPDGRMIVTEKAGKIRLIAKD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCEEEEEEEC
GTVGQPVAGVPKVDSKGQGGLLDVALSPSFAADRTIYFSYSEPRDKGNGTTVAKAKLVES
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEEEECC
DGKAKLDDVKVIFRQMPTYDGDKHFGSRLVFAPDGKLFVTVGERSDKQTRGQAQDLTSGL
CCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCHHCCHHHHHHHCC
GKVFRIDTDGNAPKDNPFTGGEKAKPEIWSYGHRNVQAAALDNQGRLWTVEHGPRGGDEL
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCC
NRPRPGLNYGWPVVTYGIEYSGEKIGDGQTQAGGTVQPVYYWDPVIGPSGMALYDKDAFP
CCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCC
AWKNQFLIGGLVSTGIVAVKLDGDKVVTEERIPLEHRVRDVRVGPDGAVYAVTEDDGQIV
CHHCCEEEEEEHHCCEEEEEECCCEEEECCCCCHHHCCEEEEECCCCEEEEEECCCCEEE
KLTPKKGS
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]