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The map label for this gene is divL [H]

Identifier: 218532773

GI number: 218532773

Start: 5209135

End: 5211663

Strand: Reverse

Name: divL [H]

Synonym: Mchl_4896

Alternate gene names: 218532773

Gene position: 5211663-5209135 (Counterclockwise)

Preceding gene: 218532774

Following gene: 218532772

Centisome position: 90.2

GC content: 71.45

Gene sequence:

>2529_bases
ATGGGTCTGGAACGGGCGGCGCGCGCCCTGTCGCGCGTCGGCGTCCTCGTCGTCGCGGCACCGGTCGCGGCACTCGCCGA
GGGCGCTCCGTCCATCGAAGCGAGGCCGATGCTGGGAGCGATGCAGACGCACAACGTTGCCGGCCTCGCCGTCGTCCTCG
GCCTGATCCTGTTCGCGACCATCCTGTCGCTGGTCTACCTGCGCGAGCGCGTCGGCTGGACGCGCAAGGAGCGCGCGCTT
CAAGACGAACTCGCCCAGCTGCGCGGCGCGCACGACCGGGCGGAGATGCTGCTCCATTCCGAGCGTCAGGTTCTCGTCGC
CTGGGCCGGGCGCGGCGAGCCGTCGATCGTCGGCGATGCGGGCTTTGCCCAAGATCTTCGAAATCAGGATCTGCGCGGTC
AGGATTCGCGCGGGCTTCAGGGCGGCTCCCGGCATCTGCTCGCCTTCGGCACGTGGCTCGCGCCGCAGGACGCGCAGCTG
CTCGACTCCGCCGTCGCGACGCTGCGCGAGCGCGGCACCGGCTTCCGGATGAACCTGCGCAGCCTCGCCGGGCGCTACAT
CGAGGCACAGGGCCAGGCGGTCGGCGGGCGGGCGCTGCTGCGCCTGCGCGAGACGACCGACGAGCGCCGTGAGCTGATCG
AGCTGCGCCACACGCTGGAGGAGGCCAATCGCGGCCTGTCCGCGCTGGCGGGCCTGCTCGATGCGCTGCCGCAGCCGATC
TGGCACCGGAGCCCGGACGGGGCGCTCGCCTTCGTCAACGCGGCCTACGCCGCCGCCGTGGAGGCCCCGAGCCGCGAGGC
CGCCCTGAGCCACGGCCTCGAACTGCTCGACCGGAGCGCCCGCGAACAGATCGTCCGGCAGGCGCGCCGGCCGGGTCTCC
CCGCCCAGGCCCTGCGCCTCTCGGCGGTGGTGGCGGGTGCGCGCCGGACCCTCGATGTCAGCGAGAGCACGCTGGAAGCC
GGCCGGGTCGGCATCGCCGTCGATGTCTCGGAGCTGGAGAGCGTACGGGCCGACCTGCAGCGCCAGATGGATGCCAACGT
CCGCACCCTCGACCAATTGCCGACCGCGGTCGCGATGTTCGACGCGCGCCAGCGCCTGATCTTCCACAACGCCGCCTACC
AGCGCCTGTGGGATCTCGACCCGGCCTTCCTCGAAGGCCGCCCGCTCGACGGCGAAATCCTCGACCGCCTGCGCGCCGCG
CGCAAACTGCCCGAGCAGGCCGATTTCCGTTCGTGGAAGACCGATGTCCTGGCCGCCTACCGCGCGGTCGAGCCCACCGA
CACGCCCTGGTACCTGCCCGACGGGCGGACGCTGCGCGTCGTCGCCGACCCCAACCCGCAGGGCGGCCTGACTTATCTCT
ACCACGACGTCTCGGAGAGCATGAAGCTCGCCTCGCGCTACGACGCGCTGATGAAGGAGCAGGCCGAGACCCTGGAAGCC
CTCAAGGAGCCGGTGGCGGTGTTCGGCGCCGACGGGCGCCTCACGGTGGCCAACCGCGCTTTCGCCGCGACCTGGCGCCT
CGACCCAGCGACGCTGGCGGGCAAACCGCATGTCGATGCGGTGATCGCCGCCTGCCGGGCGCTGACGCCGGACCAGAGCC
CCTGGGCCGGCATCCGCCAATCGGTCACCGGCCTGTCCGAGACCCGCAGCGGCCATGGCTGCCGCCTCGACATCAACGAC
GGCACGGTGCTCGATTGCTCCTCGCAGCCGCTGCCGCTCGGCGCGACGCTGCTGACCTTCATCGACGTCACCGCGAGCGC
CAATGTGGAGCGGGCGCTGACCGAGAAGAACGACGCCCTGGAGCGCGCCTCGCAACTACGCGACACCTTCGTCCACCACG
TCTCCTACGAGCTGCGCTCGCCGCTGACCAACATCATCGGCTTCACCCAGCTTCTCGGCGACGAGACCGTCGGCGCCCTG
AACGAGCGCCAGCGCGAATATTCCGAGCACATCATGCGCTCGTCGGCCGCGCTGCTCGTCATCATCAACGACATCCTCGA
CCTCGCCTCGATCGATGCCGGCTCGCTCGAACTCCAGCGCGAGACGATCGACGTGCGCGCCACCGTGGAAGCCGCCGTCC
GCGGCATCGAGGACCGGCTGGCGGAATCCGATATCGGCCTCGACCTCGACGTGCCGGAGGGTGTCGGCAGCGTGTTCGCC
GACGGCAAGCGGGTGCGTCAGATCCTGTTCAACCTGCTCTCCAACGCGGTCGGCTTCTCCGCGCCCGGCCAGCAGGTCCG
CGTCGAGGCGCGGCGCGAGGGGCGGGAATTGCGGCTGACGGTGACCGATCGCGGCCGCGGCATCGCGCCCGAGGTCATCG
ACCGGGTGTTCGACCGGTTCGAGAGCAACACGCTGGGCACCAAGCATCGCGGTGTCGGGCTGGGCCTCTCGATCGTGCGC
TCCTTCGTCGAGCTGCACGGCGGGCGGGTCGAGATCCACTCGGCACCCGGCACGGGCACCCGCGTCACCTGCCTGTTCCC
GGTCGAGCCGCCGCCGGGCAATGGCGGGCTCGCCGAGGCCGCCGAGTAG

Upstream 100 bases:

>100_bases
CGGTCGCGGCAGCGGGTATTTGCCCGGTGCGGTCCGGGAGCTTTCCAGGCGTGGGCCCGACGGCCTGCGGAGTGTGCCGG
GTTTGGGGTGGGGGCGGGAC

Downstream 100 bases:

>100_bases
GACCGGGCGCTCACGGGATCGGGATCAGGTTGGCCGCCGCCGAGGGTGCGGGGCTCACCGGAGCCGGCAAAAACGGTTAA
ACATCCCCTGCTAGAGCGCC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 842; Mature: 841

Protein sequence:

>842_residues
MGLERAARALSRVGVLVVAAPVAALAEGAPSIEARPMLGAMQTHNVAGLAVVLGLILFATILSLVYLRERVGWTRKERAL
QDELAQLRGAHDRAEMLLHSERQVLVAWAGRGEPSIVGDAGFAQDLRNQDLRGQDSRGLQGGSRHLLAFGTWLAPQDAQL
LDSAVATLRERGTGFRMNLRSLAGRYIEAQGQAVGGRALLRLRETTDERRELIELRHTLEEANRGLSALAGLLDALPQPI
WHRSPDGALAFVNAAYAAAVEAPSREAALSHGLELLDRSAREQIVRQARRPGLPAQALRLSAVVAGARRTLDVSESTLEA
GRVGIAVDVSELESVRADLQRQMDANVRTLDQLPTAVAMFDARQRLIFHNAAYQRLWDLDPAFLEGRPLDGEILDRLRAA
RKLPEQADFRSWKTDVLAAYRAVEPTDTPWYLPDGRTLRVVADPNPQGGLTYLYHDVSESMKLASRYDALMKEQAETLEA
LKEPVAVFGADGRLTVANRAFAATWRLDPATLAGKPHVDAVIAACRALTPDQSPWAGIRQSVTGLSETRSGHGCRLDIND
GTVLDCSSQPLPLGATLLTFIDVTASANVERALTEKNDALERASQLRDTFVHHVSYELRSPLTNIIGFTQLLGDETVGAL
NERQREYSEHIMRSSAALLVIINDILDLASIDAGSLELQRETIDVRATVEAAVRGIEDRLAESDIGLDLDVPEGVGSVFA
DGKRVRQILFNLLSNAVGFSAPGQQVRVEARREGRELRLTVTDRGRGIAPEVIDRVFDRFESNTLGTKHRGVGLGLSIVR
SFVELHGGRVEIHSAPGTGTRVTCLFPVEPPPGNGGLAEAAE

Sequences:

>Translated_842_residues
MGLERAARALSRVGVLVVAAPVAALAEGAPSIEARPMLGAMQTHNVAGLAVVLGLILFATILSLVYLRERVGWTRKERAL
QDELAQLRGAHDRAEMLLHSERQVLVAWAGRGEPSIVGDAGFAQDLRNQDLRGQDSRGLQGGSRHLLAFGTWLAPQDAQL
LDSAVATLRERGTGFRMNLRSLAGRYIEAQGQAVGGRALLRLRETTDERRELIELRHTLEEANRGLSALAGLLDALPQPI
WHRSPDGALAFVNAAYAAAVEAPSREAALSHGLELLDRSAREQIVRQARRPGLPAQALRLSAVVAGARRTLDVSESTLEA
GRVGIAVDVSELESVRADLQRQMDANVRTLDQLPTAVAMFDARQRLIFHNAAYQRLWDLDPAFLEGRPLDGEILDRLRAA
RKLPEQADFRSWKTDVLAAYRAVEPTDTPWYLPDGRTLRVVADPNPQGGLTYLYHDVSESMKLASRYDALMKEQAETLEA
LKEPVAVFGADGRLTVANRAFAATWRLDPATLAGKPHVDAVIAACRALTPDQSPWAGIRQSVTGLSETRSGHGCRLDIND
GTVLDCSSQPLPLGATLLTFIDVTASANVERALTEKNDALERASQLRDTFVHHVSYELRSPLTNIIGFTQLLGDETVGAL
NERQREYSEHIMRSSAALLVIINDILDLASIDAGSLELQRETIDVRATVEAAVRGIEDRLAESDIGLDLDVPEGVGSVFA
DGKRVRQILFNLLSNAVGFSAPGQQVRVEARREGRELRLTVTDRGRGIAPEVIDRVFDRFESNTLGTKHRGVGLGLSIVR
SFVELHGGRVEIHSAPGTGTRVTCLFPVEPPPGNGGLAEAAE
>Mature_841_residues
GLERAARALSRVGVLVVAAPVAALAEGAPSIEARPMLGAMQTHNVAGLAVVLGLILFATILSLVYLRERVGWTRKERALQ
DELAQLRGAHDRAEMLLHSERQVLVAWAGRGEPSIVGDAGFAQDLRNQDLRGQDSRGLQGGSRHLLAFGTWLAPQDAQLL
DSAVATLRERGTGFRMNLRSLAGRYIEAQGQAVGGRALLRLRETTDERRELIELRHTLEEANRGLSALAGLLDALPQPIW
HRSPDGALAFVNAAYAAAVEAPSREAALSHGLELLDRSAREQIVRQARRPGLPAQALRLSAVVAGARRTLDVSESTLEAG
RVGIAVDVSELESVRADLQRQMDANVRTLDQLPTAVAMFDARQRLIFHNAAYQRLWDLDPAFLEGRPLDGEILDRLRAAR
KLPEQADFRSWKTDVLAAYRAVEPTDTPWYLPDGRTLRVVADPNPQGGLTYLYHDVSESMKLASRYDALMKEQAETLEAL
KEPVAVFGADGRLTVANRAFAATWRLDPATLAGKPHVDAVIAACRALTPDQSPWAGIRQSVTGLSETRSGHGCRLDINDG
TVLDCSSQPLPLGATLLTFIDVTASANVERALTEKNDALERASQLRDTFVHHVSYELRSPLTNIIGFTQLLGDETVGALN
ERQREYSEHIMRSSAALLVIINDILDLASIDAGSLELQRETIDVRATVEAAVRGIEDRLAESDIGLDLDVPEGVGSVFAD
GKRVRQILFNLLSNAVGFSAPGQQVRVEARREGRELRLTVTDRGRGIAPEVIDRVFDRFESNTLGTKHRGVGLGLSIVRS
FVELHGGRVEIHSAPGTGTRVTCLFPVEPPPGNGGLAEAAE

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=29.3893129770992, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=31.203007518797, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=32.8, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=33.1967213114754, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1788713, Length=373, Percent_Identity=26.0053619302949, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI87081816, Length=231, Percent_Identity=32.4675324675325, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=276, Percent_Identity=28.6231884057971, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=27.5229357798165, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=23.921568627451, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1786783, Length=254, Percent_Identity=28.3464566929134, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87082128, Length=240, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1790861, Length=266, Percent_Identity=27.0676691729323, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=370, Percent_Identity=25.1351351351351, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=27.0386266094421, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790300, Length=279, Percent_Identity=25.4480286738351, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91482; Mature: 91351

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLERAARALSRVGVLVVAAPVAALAEGAPSIEARPMLGAMQTHNVAGLAVVLGLILFAT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHH
ILSLVYLRERVGWTRKERALQDELAQLRGAHDRAEMLLHSERQVLVAWAGRGEPSIVGDA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCCCCEECCC
GFAQDLRNQDLRGQDSRGLQGGSRHLLAFGTWLAPQDAQLLDSAVATLRERGTGFRMNLR
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEHH
SLAGRYIEAQGQAVGGRALLRLRETTDERRELIELRHTLEEANRGLSALAGLLDALPQPI
HHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCH
WHRSPDGALAFVNAAYAAAVEAPSREAALSHGLELLDRSAREQIVRQARRPGLPAQALRL
HCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SAVVAGARRTLDVSESTLEAGRVGIAVDVSELESVRADLQRQMDANVRTLDQLPTAVAMF
HHHHHHHHHCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DARQRLIFHNAAYQRLWDLDPAFLEGRPLDGEILDRLRAARKLPEQADFRSWKTDVLAAY
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RAVEPTDTPWYLPDGRTLRVVADPNPQGGLTYLYHDVSESMKLASRYDALMKEQAETLEA
HCCCCCCCCEECCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKEPVAVFGADGRLTVANRAFAATWRLDPATLAGKPHVDAVIAACRALTPDQSPWAGIRQ
HHCCHHEECCCCCEEEECCEEEEEEECCHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
SVTGLSETRSGHGCRLDINDGTVLDCSSQPLPLGATLLTFIDVTASANVERALTEKNDAL
HHHHHHHCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
ERASQLRDTFVHHVSYELRSPLTNIIGFTQLLGDETVGALNERQREYSEHIMRSSAALLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHH
IINDILDLASIDAGSLELQRETIDVRATVEAAVRGIEDRLAESDIGLDLDVPEGVGSVFA
HHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
DGKRVRQILFNLLSNAVGFSAPGQQVRVEARREGRELRLTVTDRGRGIAPEVIDRVFDRF
CHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHH
ESNTLGTKHRGVGLGLSIVRSFVELHGGRVEIHSAPGTGTRVTCLFPVEPPPGNGGLAEA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCC
AE
CC
>Mature Secondary Structure 
GLERAARALSRVGVLVVAAPVAALAEGAPSIEARPMLGAMQTHNVAGLAVVLGLILFAT
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHH
ILSLVYLRERVGWTRKERALQDELAQLRGAHDRAEMLLHSERQVLVAWAGRGEPSIVGDA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCCCCEECCC
GFAQDLRNQDLRGQDSRGLQGGSRHLLAFGTWLAPQDAQLLDSAVATLRERGTGFRMNLR
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEHH
SLAGRYIEAQGQAVGGRALLRLRETTDERRELIELRHTLEEANRGLSALAGLLDALPQPI
HHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCH
WHRSPDGALAFVNAAYAAAVEAPSREAALSHGLELLDRSAREQIVRQARRPGLPAQALRL
HCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SAVVAGARRTLDVSESTLEAGRVGIAVDVSELESVRADLQRQMDANVRTLDQLPTAVAMF
HHHHHHHHHCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DARQRLIFHNAAYQRLWDLDPAFLEGRPLDGEILDRLRAARKLPEQADFRSWKTDVLAAY
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RAVEPTDTPWYLPDGRTLRVVADPNPQGGLTYLYHDVSESMKLASRYDALMKEQAETLEA
HCCCCCCCCEECCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKEPVAVFGADGRLTVANRAFAATWRLDPATLAGKPHVDAVIAACRALTPDQSPWAGIRQ
HHCCHHEECCCCCEEEECCEEEEEEECCHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
SVTGLSETRSGHGCRLDINDGTVLDCSSQPLPLGATLLTFIDVTASANVERALTEKNDAL
HHHHHHHCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
ERASQLRDTFVHHVSYELRSPLTNIIGFTQLLGDETVGALNERQREYSEHIMRSSAALLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHH
IINDILDLASIDAGSLELQRETIDVRATVEAAVRGIEDRLAESDIGLDLDVPEGVGSVFA
HHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
DGKRVRQILFNLLSNAVGFSAPGQQVRVEARREGRELRLTVTDRGRGIAPEVIDRVFDRF
CHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHH
ESNTLGTKHRGVGLGLSIVRSFVELHGGRVEIHSAPGTGTRVTCLFPVEPPPGNGGLAEA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCC
AE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]