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The map label for this gene is nahR [H]

Identifier: 218710392

GI number: 218710392

Start: 2599287

End: 2600213

Strand: Reverse

Name: nahR [H]

Synonym: VS_2429

Alternate gene names: 218710392

Gene position: 2600213-2599287 (Counterclockwise)

Preceding gene: 218710394

Following gene: 218710391

Centisome position: 78.81

GC content: 43.58

Gene sequence:

>927_bases
GTGGCTGATTTTAACTGGAAAGGAATTGACCTTAACTTATTGATTGCACTGCAAGCTCTGTATAAAACCAACAGTGTGAG
TAAGGCGGCAGAACGTTGTTATGTCAGCCAATCTGCGATGAGTCATAGCTTACAAAGACTGAGAAAGCTGTTTGATGACC
CTCTGTTTGAGCGTGTCGGTAGCAAGATGGAGGCGACCGATCGAGCCATTGAACTGTCCAGTACGGTAGAAGCTCTGCTC
AATACCATCCAGTCAGAGGTGTTACTGTCTAAATCGTTTGATGCCGCGACTTATAAAGGGACTTGGAAGATTGGTCTTAC
CGATTATGCTGAGCAGATGTTCGCGCCAGCATTGTTTGACCTCATCAAGCAATCCTCTCCTAATTCGCAAGTCGTGCTGT
TCAATGTAAACCGGAGTAACTATCAGCAAGTATTTGAAGACGCCAAGCTTGATATGGCAATAGGCAGTTTTGGTGAGGTC
TCAAAGCAATATCGAACCACGCATTTGTACACAGAGCAACATGTCTGTTTATTCGACAAGTCGGTTGTATCTATTGAGGG
GCCGATATCGTTAGAACAGTTTGTTGCTGTCGAGCATGCTCTTGTTTCACCTGCTGGATCTTTAAAGACTGGCGTTGATA
AACGTTTGGCTGAATTAGGCTTCAGCCGAAAAGTGGCTATATGTTCAAGCAATTTTTTAACAGTAAAACGTTTGATAAGA
GGTAGGGAGTTATTGTGTATCGTCCCCAAACTGGTGGCACGCAATGATATTCAAGACCAAGATACCGTGGTAGCAGTGGA
GCCACCTATCGATGTGCCTGATTTTGATATACAGCTCATCTATCGCAAGACTAAGCATTTAGATGATAAAAATAAGCTAC
TTAGGAAGCTTTTTACACAAGCCGTTTCATCTGTGGTTGCTGCATAG

Upstream 100 bases:

>100_bases
GATCGATTCCAGATAAATGTTTAGCGTAATTTAGGTGGAGTTGAACTATGATTCAAATTAATTGTTTTAATTATAACTAT
GAATGATATGGGATTGATTT

Downstream 100 bases:

>100_bases
TTGCAGTAGTTGTTCGGTCATCAATTTTATGCGAATTATTTTTAGAAAAATCCGGCTTATTATAAGAACCCGACTATACT
TAATTTAAGGCTCAAAGCAG

Product: putative LysR-like regular protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MADFNWKGIDLNLLIALQALYKTNSVSKAAERCYVSQSAMSHSLQRLRKLFDDPLFERVGSKMEATDRAIELSSTVEALL
NTIQSEVLLSKSFDAATYKGTWKIGLTDYAEQMFAPALFDLIKQSSPNSQVVLFNVNRSNYQQVFEDAKLDMAIGSFGEV
SKQYRTTHLYTEQHVCLFDKSVVSIEGPISLEQFVAVEHALVSPAGSLKTGVDKRLAELGFSRKVAICSSNFLTVKRLIR
GRELLCIVPKLVARNDIQDQDTVVAVEPPIDVPDFDIQLIYRKTKHLDDKNKLLRKLFTQAVSSVVAA

Sequences:

>Translated_308_residues
MADFNWKGIDLNLLIALQALYKTNSVSKAAERCYVSQSAMSHSLQRLRKLFDDPLFERVGSKMEATDRAIELSSTVEALL
NTIQSEVLLSKSFDAATYKGTWKIGLTDYAEQMFAPALFDLIKQSSPNSQVVLFNVNRSNYQQVFEDAKLDMAIGSFGEV
SKQYRTTHLYTEQHVCLFDKSVVSIEGPISLEQFVAVEHALVSPAGSLKTGVDKRLAELGFSRKVAICSSNFLTVKRLIR
GRELLCIVPKLVARNDIQDQDTVVAVEPPIDVPDFDIQLIYRKTKHLDDKNKLLRKLFTQAVSSVVAA
>Mature_307_residues
ADFNWKGIDLNLLIALQALYKTNSVSKAAERCYVSQSAMSHSLQRLRKLFDDPLFERVGSKMEATDRAIELSSTVEALLN
TIQSEVLLSKSFDAATYKGTWKIGLTDYAEQMFAPALFDLIKQSSPNSQVVLFNVNRSNYQQVFEDAKLDMAIGSFGEVS
KQYRTTHLYTEQHVCLFDKSVVSIEGPISLEQFVAVEHALVSPAGSLKTGVDKRLAELGFSRKVAICSSNFLTVKRLIRG
RELLCIVPKLVARNDIQDQDTVVAVEPPIDVPDFDIQLIYRKTKHLDDKNKLLRKLFTQAVSSVVAA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081766, Length=245, Percent_Identity=26.9387755102041, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786820, Length=260, Percent_Identity=27.3076923076923, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081684, Length=200, Percent_Identity=25, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34458; Mature: 34327

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFNWKGIDLNLLIALQALYKTNSVSKAAERCYVSQSAMSHSLQRLRKLFDDPLFERVG
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
SKMEATDRAIELSSTVEALLNTIQSEVLLSKSFDAATYKGTWKIGLTDYAEQMFAPALFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEECHHHHHHHHHHHHHHH
LIKQSSPNSQVVLFNVNRSNYQQVFEDAKLDMAIGSFGEVSKQYRTTHLYTEQHVCLFDK
HHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCEEEECC
SVVSIEGPISLEQFVAVEHALVSPAGSLKTGVDKRLAELGFSRKVAICSSNFLTVKRLIR
CEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHC
GRELLCIVPKLVARNDIQDQDTVVAVEPPIDVPDFDIQLIYRKTKHLDDKNKLLRKLFTQ
CCCEEEHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHEEEHHHHCCCHHHHHHHHHHHH
AVSSVVAA
HHHHHHCC
>Mature Secondary Structure 
ADFNWKGIDLNLLIALQALYKTNSVSKAAERCYVSQSAMSHSLQRLRKLFDDPLFERVG
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
SKMEATDRAIELSSTVEALLNTIQSEVLLSKSFDAATYKGTWKIGLTDYAEQMFAPALFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEECHHHHHHHHHHHHHHH
LIKQSSPNSQVVLFNVNRSNYQQVFEDAKLDMAIGSFGEVSKQYRTTHLYTEQHVCLFDK
HHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCEEEECC
SVVSIEGPISLEQFVAVEHALVSPAGSLKTGVDKRLAELGFSRKVAICSSNFLTVKRLIR
CEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHC
GRELLCIVPKLVARNDIQDQDTVVAVEPPIDVPDFDIQLIYRKTKHLDDKNKLLRKLFTQ
CCCEEEHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHEEEHHHHCCCHHHHHHHHHHHH
AVSSVVAA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]