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The map label for this gene is nrdR [H]

Identifier: 218710377

GI number: 218710377

Start: 2583311

End: 2583760

Strand: Reverse

Name: nrdR [H]

Synonym: VS_2414

Alternate gene names: 218710377

Gene position: 2583760-2583311 (Counterclockwise)

Preceding gene: 218710378

Following gene: 218710376

Centisome position: 78.31

GC content: 46.22

Gene sequence:

>450_bases
ATGCATTGTCCTTTTTGTTCAGAGAACGACACTAAAGTAATCGATTCAAGACTGGTAGCCGATGGCCATCAGGTTCGTCG
TCGCCGTCAATGCCTTGCATGTAGTGAACGTTTTACGACGTTCGAATCGGCAGAACTTGTGATGCCTAAAGTCATAAAGT
CGAATGGAAACCGCGAACCATTTAATGAAGATAAAATGGTCGGTGGTGTGCAGCGCGCCCTAGAAAAACGCCCAGTGAGT
GCTGATGCGATTGAACTTGCGATCAGCACGATTAAGTCACAACTCCGTGCGACTGGTGAGCGTGAAGTACCAAGCGAGAT
GATTGGTAACCTTGTGATGGGCCAATTGAAAGAATTGGACAAAGTGGCGTACATTCGTTTTGCCTCTGTTTACCGCAGCT
TTGAAGACATCCGAGAGTTTGGCGAAGAAATCGCTAAATTAGAGGATTAA

Upstream 100 bases:

>100_bases
TAATCAATGAATTACCACACAAAAGGGCCTTAATTGGCCCTTTTTCTTTCCTAACGTTTGTCAATTCCGTTACACTGATA
TTCAATTATTTGGAGGTGAT

Downstream 100 bases:

>100_bases
CTCCTCAATCATGTCAAACTTTACTCCCCTAGATTTTCAAATGATGTCACGTGCTATTAAGTTAGCCAAACGCGGCATTT
ACACTACTGCACCAAACCCG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREPFNEDKMVGGVQRALEKRPVS
ADAIELAISTIKSQLRATGEREVPSEMIGNLVMGQLKELDKVAYIRFASVYRSFEDIREFGEEIAKLED

Sequences:

>Translated_149_residues
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREPFNEDKMVGGVQRALEKRPVS
ADAIELAISTIKSQLRATGEREVPSEMIGNLVMGQLKELDKVAYIRFASVYRSFEDIREFGEEIAKLED
>Mature_149_residues
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREPFNEDKMVGGVQRALEKRPVS
ADAIELAISTIKSQLRATGEREVPSEMIGNLVMGQLKELDKVAYIRFASVYRSFEDIREFGEEIAKLED

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=79.1946308724832, Blast_Score=245, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 16912; Mature: 16912

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREP
CCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FNEDKMVGGVQRALEKRPVSADAIELAISTIKSQLRATGEREVPSEMIGNLVMGQLKELD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDIREFGEEIAKLED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREP
CCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FNEDKMVGGVQRALEKRPVSADAIELAISTIKSQLRATGEREVPSEMIGNLVMGQLKELD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDIREFGEEIAKLED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]