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The map label for this gene is yaeL [C]

Identifier: 218710311

GI number: 218710311

Start: 2514889

End: 2516247

Strand: Reverse

Name: yaeL [C]

Synonym: VS_2345

Alternate gene names: 218710311

Gene position: 2516247-2514889 (Counterclockwise)

Preceding gene: 218710312

Following gene: 218710310

Centisome position: 76.27

GC content: 43.78

Gene sequence:

>1359_bases
ATGAGTGGAATTCTGTGGAACTTCGCATCTTTTATTGTAGCGCTTGGTATTCTGGTTGCTGTTCATGAGTTTGGACACTT
CTGGGTTGCTCGTCGTTGTGGTGTGAAAGTAGAAAAATTCTCGATTGGTTTTGGTAAATCAATCTGGAGCAAGATCGGCC
GTGATGGTACAGAGTACAGCTTGTCAGTGATTCCGCTAGGCGGCTACGTTAAGATGCTCGATGGGCGTGTTGATGACCTT
TCTGAAGACGAACAGCAATACGCTTTTGATAAGAAACCGTTGTGGAAGCGAACGGCGATTGTGGGTGCAGGTCCAGCATT
CAACTTTATATTTGCCGTGTTCGCATATTGGCTGGTTTTTTTTATTGGTGTTCCAGCGGTTAAGCCTGTGATTGGAGAGG
TCACCCCGCAATCTATTGTTGCACAAGCCGGAATTGAAAGTGGAATGGAACTTAAATCTATTTCAGGAATCAAAACCGCA
GATTGGGAATCAGTAAACTTGGGTTTGATATCACATATTGGTGATGAGTCCATGACTGTAACGGTTTCTTCTCAAGACGA
CATCGGCCTTGAACAACAGATAACATTGGATATTTCTGACTGGTCGTTCAACCCAGAAACTGAGTCAGCAATGACAACGC
TTGGTTTTAGACCGTATTCTCCAGAGATATCGACAGTGCTCGCTCAAGTTATTGATGACGGTGCTGCCTATTCTGCAGGG
CTAGAGTCTGGCGACAAAATTGTCGAAATTAATGGTCAGCCTATTGAACAGTGGAAGTCGGTTGTTGAATTAATCCGTTC
ACACCCAATGATGCCCTTGGACCTTGTCGTATTACGAAATGGTGTTGAGCGGTCCTTGGTTATGACGCCCAATAGTCGCG
AATTTTCTGATGGTTCTACAATCGGCTATGCGGGTATTGCTCCCGAAGTCGCAGAATGGCCAGAAGATTATCGCTTTGAG
TTACAATTTGGTGTAATTGAGTCTGTAGGAAAAGCATTTGATAAAACAGGTCAAATCATAGGTTTGACGCTGACAATGCT
TAAGAAGCTCATCGTTGGTGATGTTGGCTTAAATAACTTGAGTGGCCCAATTTCAATTGCTAAAGGCGCAGGGGCAACCG
CCGATTACGGTTTGGTTTACTTCTTAGGTTTTTTAGCTCTGATTAGTGTTAACTTGGGTATTATTAATTTAGTTCCGCTG
CCTATGCTTGATGGCGGACATTTGCTCTTTTTCGCTATTGAGGCCGTTACTCGTAAACCTGTACCTGAAAAAGTTCAAGA
AATGGGATACAGAGTGGGAGGCGCAATCCTCTTCTCTTTGATGGCTCTGGCAATATTTAATGATTTTACTCGTCTGTGA

Upstream 100 bases:

>100_bases
AACAACATAACTCTGAGGGCTTAGATAGCTTGGAAAGCCTTCTTGAGCTAGATAATATGTCTCGTCAAATAGCCATTCAA
TTTATTAAAGAGCAGCTAGC

Downstream 100 bases:

>100_bases
ATGGTTTCTCACAGGCATTGGTAGTAGCAAGGAATAATTAGAATAAGTATGGCGATTAAGCAAATTCTGTTCGCAAGTCT
ATTGGCCACTAGTGTGGCTG

Product: putative M50 family membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSGILWNFASFIVALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWSKIGRDGTEYSLSVIPLGGYVKMLDGRVDDL
SEDEQQYAFDKKPLWKRTAIVGAGPAFNFIFAVFAYWLVFFIGVPAVKPVIGEVTPQSIVAQAGIESGMELKSISGIKTA
DWESVNLGLISHIGDESMTVTVSSQDDIGLEQQITLDISDWSFNPETESAMTTLGFRPYSPEISTVLAQVIDDGAAYSAG
LESGDKIVEINGQPIEQWKSVVELIRSHPMMPLDLVVLRNGVERSLVMTPNSREFSDGSTIGYAGIAPEVAEWPEDYRFE
LQFGVIESVGKAFDKTGQIIGLTLTMLKKLIVGDVGLNNLSGPISIAKGAGATADYGLVYFLGFLALISVNLGIINLVPL
PMLDGGHLLFFAIEAVTRKPVPEKVQEMGYRVGGAILFSLMALAIFNDFTRL

Sequences:

>Translated_452_residues
MSGILWNFASFIVALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWSKIGRDGTEYSLSVIPLGGYVKMLDGRVDDL
SEDEQQYAFDKKPLWKRTAIVGAGPAFNFIFAVFAYWLVFFIGVPAVKPVIGEVTPQSIVAQAGIESGMELKSISGIKTA
DWESVNLGLISHIGDESMTVTVSSQDDIGLEQQITLDISDWSFNPETESAMTTLGFRPYSPEISTVLAQVIDDGAAYSAG
LESGDKIVEINGQPIEQWKSVVELIRSHPMMPLDLVVLRNGVERSLVMTPNSREFSDGSTIGYAGIAPEVAEWPEDYRFE
LQFGVIESVGKAFDKTGQIIGLTLTMLKKLIVGDVGLNNLSGPISIAKGAGATADYGLVYFLGFLALISVNLGIINLVPL
PMLDGGHLLFFAIEAVTRKPVPEKVQEMGYRVGGAILFSLMALAIFNDFTRL
>Mature_451_residues
SGILWNFASFIVALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWSKIGRDGTEYSLSVIPLGGYVKMLDGRVDDLS
EDEQQYAFDKKPLWKRTAIVGAGPAFNFIFAVFAYWLVFFIGVPAVKPVIGEVTPQSIVAQAGIESGMELKSISGIKTAD
WESVNLGLISHIGDESMTVTVSSQDDIGLEQQITLDISDWSFNPETESAMTTLGFRPYSPEISTVLAQVIDDGAAYSAGL
ESGDKIVEINGQPIEQWKSVVELIRSHPMMPLDLVVLRNGVERSLVMTPNSREFSDGSTIGYAGIAPEVAEWPEDYRFEL
QFGVIESVGKAFDKTGQIIGLTLTMLKKLIVGDVGLNNLSGPISIAKGAGATADYGLVYFLGFLALISVNLGIINLVPLP
MLDGGHLLFFAIEAVTRKPVPEKVQEMGYRVGGAILFSLMALAIFNDFTRL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=454, Percent_Identity=53.9647577092511, Blast_Score=488, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49121; Mature: 48990

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGILWNFASFIVALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWSKIGRDGTEYS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCEE
LSVIPLGGYVKMLDGRVDDLSEDEQQYAFDKKPLWKRTAIVGAGPAFNFIFAVFAYWLVF
EEEEECCCCCEECCCCCCCCCCHHHHHHCCCCCCHHHHEEEECCHHHHHHHHHHHHHHHH
FIGVPAVKPVIGEVTPQSIVAQAGIESGMELKSISGIKTADWESVNLGLISHIGDESMTV
HHCCCHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCHHHHHCCCCCEEE
TVSSQDDIGLEQQITLDISDWSFNPETESAMTTLGFRPYSPEISTVLAQVIDDGAAYSAG
EEECCCCCCCCEEEEEEEECCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHCC
LESGDKIVEINGQPIEQWKSVVELIRSHPMMPLDLVVLRNGVERSLVMTPNSREFSDGST
CCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCC
IGYAGIAPEVAEWPEDYRFELQFGVIESVGKAFDKTGQIIGLTLTMLKKLIVGDVGLNNL
EEECCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCC
SGPISIAKGAGATADYGLVYFLGFLALISVNLGIINLVPLPMLDGGHLLFFAIEAVTRKP
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEHHHHHHHCCC
VPEKVQEMGYRVGGAILFSLMALAIFNDFTRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGILWNFASFIVALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWSKIGRDGTEYS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCEE
LSVIPLGGYVKMLDGRVDDLSEDEQQYAFDKKPLWKRTAIVGAGPAFNFIFAVFAYWLVF
EEEEECCCCCEECCCCCCCCCCHHHHHHCCCCCCHHHHEEEECCHHHHHHHHHHHHHHHH
FIGVPAVKPVIGEVTPQSIVAQAGIESGMELKSISGIKTADWESVNLGLISHIGDESMTV
HHCCCHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCHHHHHCCCCCEEE
TVSSQDDIGLEQQITLDISDWSFNPETESAMTTLGFRPYSPEISTVLAQVIDDGAAYSAG
EEECCCCCCCCEEEEEEEECCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHCC
LESGDKIVEINGQPIEQWKSVVELIRSHPMMPLDLVVLRNGVERSLVMTPNSREFSDGST
CCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCC
IGYAGIAPEVAEWPEDYRFELQFGVIESVGKAFDKTGQIIGLTLTMLKKLIVGDVGLNNL
EEECCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCC
SGPISIAKGAGATADYGLVYFLGFLALISVNLGIINLVPLPMLDGGHLLFFAIEAVTRKP
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEHHHHHHHCCC
VPEKVQEMGYRVGGAILFSLMALAIFNDFTRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]