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The map label for this gene is queC [H]

Identifier: 218709345

GI number: 218709345

Start: 1465899

End: 1466492

Strand: Direct

Name: queC [H]

Synonym: VS_1354

Alternate gene names: 218709345

Gene position: 1465899-1466492 (Clockwise)

Preceding gene: 218709344

Following gene: 218709349

Centisome position: 44.43

GC content: 42.76

Gene sequence:

>594_bases
ATGAAAAAAGCAGTTGTAGTATTCAGTGGTGGTCAAGACTCAACAACGTGTCTTGTTCAAGCATTAAAAGAGTATGATGA
AGTTCATGCGATTACGTTTGATTATGGTCAGCGCCATAGACTCGAGATCGAAGTTGCTGAGTCATTGTCGAAAGAACTTG
GTGTGAAAGCGCACAAAGTAATGGATGTGACTCTGTTGAATGAACTGGCTATTAGCTCTCTTACTCGTGACGATATTCCC
GTCTCTCATGAGCTACAAGAGAATGGGCTACCGAATTCTTTCGTTCCCGGTCGTAATATTCTGTTCTTAACTTTGGCGGG
TATTTACGCTTACCAAATCGGTGCAAATACCGTAATCACGGGTGTGTGTGAAACAGATTTTTCAGGCTACCCTGATTGTC
GTAATGACTTTGTGAAAGCGATGAACTCTGCGCTTGTACAAGGTATGGACAAGCCGCTTGATATTAAAACACCGTTAATG
TGGTTAAACAAGGCTGAGACATGGGCGTTGGCAGATCAGTATTCAGCACTCGAACTTGTTAGAAACAAAACACTGACCTG
CTACAACGGTATTATCGGTTCGGCAACATGTTGA

Upstream 100 bases:

>100_bases
CTTATCAATCCAAACTCACAAATATTTGAGCATCGCATAGGTTGTATTTGTTTACTTGCCTATATAAGTCGCTAGTAGAA
GATTCTCGTAAGGATTTAAG

Downstream 100 bases:

>100_bases
CAGTTTTTTTTATTTTCACGTTAAAAGAGCCATATATCAGTGGGTTATGTTAATATTTTTGATTGTCGTTGACTGTCAAC
AAAATCAGAATAAATTCCTC

Product: putative ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKKAVVVFSGGQDSTTCLVQALKEYDEVHAITFDYGQRHRLEIEVAESLSKELGVKAHKVMDVTLLNELAISSLTRDDIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGANTVITGVCETDFSGYPDCRNDFVKAMNSALVQGMDKPLDIKTPLM
WLNKAETWALADQYSALELVRNKTLTCYNGIIGSATC

Sequences:

>Translated_197_residues
MKKAVVVFSGGQDSTTCLVQALKEYDEVHAITFDYGQRHRLEIEVAESLSKELGVKAHKVMDVTLLNELAISSLTRDDIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGANTVITGVCETDFSGYPDCRNDFVKAMNSALVQGMDKPLDIKTPLM
WLNKAETWALADQYSALELVRNKTLTCYNGIIGSATC
>Mature_197_residues
MKKAVVVFSGGQDSTTCLVQALKEYDEVHAITFDYGQRHRLEIEVAESLSKELGVKAHKVMDVTLLNELAISSLTRDDIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGANTVITGVCETDFSGYPDCRNDFVKAMNSALVQGMDKPLDIKTPLM
WLNKAETWALADQYSALELVRNKTLTCYNGIIGSATC

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=194, Percent_Identity=72.680412371134, Blast_Score=303, Evalue=4e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 21694; Mature: 21694

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAVVVFSGGQDSTTCLVQALKEYDEVHAITFDYGQRHRLEIEVAESLSKELGVKAHKV
CCCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCEEEEEHHHHHHHHHHCCCHHHH
MDVTLLNELAISSLTRDDIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGANTVIT
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEE
GVCETDFSGYPDCRNDFVKAMNSALVQGMDKPLDIKTPLMWLNKAETWALADQYSALELV
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHH
RNKTLTCYNGIIGSATC
HCCCCEEECCCCCCCCC
>Mature Secondary Structure
MKKAVVVFSGGQDSTTCLVQALKEYDEVHAITFDYGQRHRLEIEVAESLSKELGVKAHKV
CCCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCEEEEEHHHHHHHHHHCCCHHHH
MDVTLLNELAISSLTRDDIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGANTVIT
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEE
GVCETDFSGYPDCRNDFVKAMNSALVQGMDKPLDIKTPLMWLNKAETWALADQYSALELV
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHH
RNKTLTCYNGIIGSATC
HCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA