Click here to switch to the map view.

The map label for this gene is speB [H]

Identifier: 218709232

GI number: 218709232

Start: 1316200

End: 1317126

Strand: Direct

Name: speB [H]

Synonym: VS_1239

Alternate gene names: 218709232

Gene position: 1316200-1317126 (Clockwise)

Preceding gene: 218709231

Following gene: 218709233

Centisome position: 39.89

GC content: 46.39

Gene sequence:

>927_bases
ATGAACGATCTATTTACCAAACCAGATTACTCGCTGTACTCCAACGCGATGACGTTTATGCGTCGCCCATTGGTGCAGAA
CCCAATTGATAACGATGCTGATGTGGTTGTGTTGGGCGCGCCGTTAGATATGGCGACGTCGGGTCGTCCGGGTGCTCGTA
TGGGACCTGATGCGATTCGTCGTGCGTCTGTAAACTTGGCGTGGGAAGGCAAAAAATTTCCTTGGGACTTCAATGTATTT
GAACACACCTCGGTGATTGATGCTGGCGATCTTGTGTTTGATTGCGGTGATGCAGAAGACTTAACTCAGCGTCTAGAAGC
AGCCGCTGATGCGATTCTAAACAGCGGTAAAACACTGTTAGGGTTAGGTGGCGATCACTTCATTACATTGCCTTTGCTAA
GAGCATACGGCAAGAAGTACGGTGAAATGGCTCTGATTCATTTTGACGCGCACACTGATACTTACAGTCAGGGTAGTCGT
TACGATCACGGTACTATGTTCTACCATGCGCCAAATGAAGGGTTAATCTCGCCTGAGCATTCTGTGCAAATAGGTATTCG
TACAGAGTATAAGCAGGAAGGTCACGGCTTTAATGTTATTAATGCGATGCAAGCGAATGACATGAGCGTGGATGAGATCA
TTGCTCAAGTAAAAGGTATTGTTGGCGACAAACCTGTTTATGTAACGTTTGATATTGACTGTCTAGACCCTGCGTTTGCA
CCGGGTACGGGCACACCAGTGTGTGGTGGTTTGAATTCAGATAAAGTGCTCAAAATAATCCGTGGCTTACAAGGTATCAA
CATGGTTGGTATGGATGTGGTAGAAGTGTCTCCAGCCTATGACCAAAGCGAAATTACCGCTCTAGCTGGTGCAACTATCG
CACTTGAGCTGCTTTACGTTTGGACGGCAAATCGCTTAACAAAATAA

Upstream 100 bases:

>100_bases
AAGATTTGGTCACAGCGAAAGTACCAGCACAAGAGCAGCAAAGCGTACTTGAAGAGTTAGAGCAAGGCTTGATGGGTTAC
ACCTATCTTGAGGATTTTTA

Downstream 100 bases:

>100_bases
AATAGTTAGCGAGCCATGTTGAACGTGACAATCTCGTTTTACGGATAAACACCATATTGCGGTACATGATCTTCTAAAAG
CCGCCCGAGTTAAACTCGGG

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNDLFTKPDYSLYSNAMTFMRRPLVQNPIDNDADVVVLGAPLDMATSGRPGARMGPDAIRRASVNLAWEGKKFPWDFNVF
EHTSVIDAGDLVFDCGDAEDLTQRLEAAADAILNSGKTLLGLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSQGSR
YDHGTMFYHAPNEGLISPEHSVQIGIRTEYKQEGHGFNVINAMQANDMSVDEIIAQVKGIVGDKPVYVTFDIDCLDPAFA
PGTGTPVCGGLNSDKVLKIIRGLQGINMVGMDVVEVSPAYDQSEITALAGATIALELLYVWTANRLTK

Sequences:

>Translated_308_residues
MNDLFTKPDYSLYSNAMTFMRRPLVQNPIDNDADVVVLGAPLDMATSGRPGARMGPDAIRRASVNLAWEGKKFPWDFNVF
EHTSVIDAGDLVFDCGDAEDLTQRLEAAADAILNSGKTLLGLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSQGSR
YDHGTMFYHAPNEGLISPEHSVQIGIRTEYKQEGHGFNVINAMQANDMSVDEIIAQVKGIVGDKPVYVTFDIDCLDPAFA
PGTGTPVCGGLNSDKVLKIIRGLQGINMVGMDVVEVSPAYDQSEITALAGATIALELLYVWTANRLTK
>Mature_308_residues
MNDLFTKPDYSLYSNAMTFMRRPLVQNPIDNDADVVVLGAPLDMATSGRPGARMGPDAIRRASVNLAWEGKKFPWDFNVF
EHTSVIDAGDLVFDCGDAEDLTQRLEAAADAILNSGKTLLGLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSQGSR
YDHGTMFYHAPNEGLISPEHSVQIGIRTEYKQEGHGFNVINAMQANDMSVDEIIAQVKGIVGDKPVYVTFDIDCLDPAFA
PGTGTPVCGGLNSDKVLKIIRGLQGINMVGMDVVEVSPAYDQSEITALAGATIALELLYVWTANRLTK

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=291, Percent_Identity=41.9243986254296, Blast_Score=205, Evalue=4e-53,
Organism=Homo sapiens, GI10947139, Length=303, Percent_Identity=24.0924092409241, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4502215, Length=296, Percent_Identity=24.3243243243243, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1789306, Length=305, Percent_Identity=62.2950819672131, Blast_Score=388, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6325146, Length=228, Percent_Identity=26.7543859649123, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33534; Mature: 33534

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLFTKPDYSLYSNAMTFMRRPLVQNPIDNDADVVVLGAPLDMATSGRPGARMGPDAIR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
RASVNLAWEGKKFPWDFNVFEHTSVIDAGDLVFDCGDAEDLTQRLEAAADAILNSGKTLL
HHCEEEEECCCCCCEECCCCCCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHHCCCEEE
GLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSQGSRYDHGTMFYHAPNEGLISPEH
ECCCCCEEHHHHHHHHCHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEYKQEGHGFNVINAMQANDMSVDEIIAQVKGIVGDKPVYVTFDIDCLDPAFA
CEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
PGTGTPVCGGLNSDKVLKIIRGLQGINMVGMDVVEVSPAYDQSEITALAGATIALELLYV
CCCCCCEECCCCHHHHHHHHHHCCCCCEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
WTANRLTK
HHHHHCCC
>Mature Secondary Structure
MNDLFTKPDYSLYSNAMTFMRRPLVQNPIDNDADVVVLGAPLDMATSGRPGARMGPDAIR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
RASVNLAWEGKKFPWDFNVFEHTSVIDAGDLVFDCGDAEDLTQRLEAAADAILNSGKTLL
HHCEEEEECCCCCCEECCCCCCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHHCCCEEE
GLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSQGSRYDHGTMFYHAPNEGLISPEH
ECCCCCEEHHHHHHHHCHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEYKQEGHGFNVINAMQANDMSVDEIIAQVKGIVGDKPVYVTFDIDCLDPAFA
CEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
PGTGTPVCGGLNSDKVLKIIRGLQGINMVGMDVVEVSPAYDQSEITALAGATIALELLYV
CCCCCCEECCCCHHHHHHHHHHCCCCCEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
WTANRLTK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA