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The map label for this gene is speA [H]

Identifier: 218709231

GI number: 218709231

Start: 1314293

End: 1316200

Strand: Direct

Name: speA [H]

Synonym: VS_1238

Alternate gene names: 218709231

Gene position: 1314293-1316200 (Clockwise)

Preceding gene: 218709226

Following gene: 218709232

Centisome position: 39.84

GC content: 45.6

Gene sequence:

>1908_bases
TTGGAAAATTCGGTTAATTTGGAACGCATCCGTGCTGAGTATAATGTAAAGCACTGGAGCCAAGGTTTTTATGGAATTGA
TGATAATGGCGAGGTGTATGTATCACCGAGCGAAACCGATCATCAAGTTCCGCTAAGTCAGATCGTAAAACAGTTAGAGC
AGAGAAATATTGGTTTGCCTGCTCTTGTGCGTTTTCCTCAAATAGTGCATCAACGTGTGCACAATATCTGTAACGCATTT
AACCAAGCGATCGATGAATATCAGTATGACAATCGTTACTTGCTTGTTTACCCGATTAAAGTTAACCAACAAAAAGAAGT
GGTTGATGAGATCTTAGCGAGCCAAGCTCAATTAGAGCAAAAGCAGCTAGGCCTAGAGGCGGGCAGCAAGCCTGAACTAT
TAGCGGTATTGGCACTGGCTCAAAAAGCGAGCTCGGTGATCGTGTGTAACGGTTACAAAGACAGAGAATACATCCGTCTT
GCTCTTATTGGCGAAAAGCTGGGTCATAAAGTATTTATCGTTCTAGAGAAGCTATCTGAGCTTGATCTTGTTCTTTCTGA
AGCGAAAGCGCTTGGCGTGAAACCTCGTTTAGGTTTACGTATTCGTCTTGCTTCTCAAGGCGCAGGTAAATGGCAAGCAA
GTGGTGGTGAGAAGTCGAAGTTTGGCTTGTCTGCATCACAAGTGCTTACTGTTATCGAACGTTTGAAAGCTGAAGACCAG
TTGGATGTTCTAGAGCTCGTGCACTTCCACCTTGGTTCACAAATGGCGAACATTCGTGATGTGCGCAATGGTGTGAGTGA
AGCGGCTCGTTTCTACTGTGAACTGCGTGATATTGGCGCTCAACTGAAGTTCTTGGATGTTGGTGGCGGTTTGGCGGTCG
ATTACGACGGCACACGTAGCCAGTCTTCAAACTCAATGAACTACGGCTTGCTTGAGTACGCTCGTAACATAGTGATGACA
GTAGGGGATATTTGTAAGCTCTACAATCAGCCACAACCTGTGATTATTTCAGAATCTGGTCGCTCGCTGACAGCGCACCA
TGCTGTACTGATCACCAACGTTATTGGTACTGAAAGCTACTCGCCGGAAGACATGGCAGCACCAGAAGCAGACGCGCCAA
TGTTGCTAAACAACATGTGGAAGAACTTCTTAGAGCTCGATGCTGGTAATGATGACCGTGCGTTGATTGAGATCTACAAC
GACACTCAGAGCGATATTGCAGAAGCACACAACCAATTTGCGACGGGTATGCTGAACCTTCAGCACCGTGCTTGGGCAGA
GCAGATGTCTTTGCGCATTAACTACGAACTTAGCTCTCGTATGAGTACTAAGAACCGTTACCACCGTCCTATTTTGGATG
AGTTGAGCGAGCGTTTGGCTGATAAGTTTTTCGTGAACTTCTCGCTGTTCCAATCGTTGCCAGATGCTTGGGGTATCGAT
CAGGTGTTCCCTGTATTGCCTCTAAGTGGTTTGGATAATGCGGACGAGCGACGCGCTGTAGTATTGGATATTACTTGTGA
TTCTGACGGTACGATTGACCAGTATGTTGATGGCCAAGGTATTGAAACGACTCTGCCAGTTCCTGCATGGAACCCAGATG
AACCATACCTGATGGGCTTTTTCTTAGTAGGCGCATACCAAGAGATCTTGGGTGATATGCACAACCTATTTGGTGATACC
CACAGTGTAGTGGTGAATGTTGATGAAAGTGGTCAAGCGAATATCGACTACATCAACGAAGGCGATACGGTTGAAGACAT
GATGCGTTATGTTCACATCGATACAGATCTGATTCGTCAGAACTACAAAGATTTGGTCACAGCGAAAGTACCAGCACAAG
AGCAGCAAAGCGTACTTGAAGAGTTAGAGCAAGGCTTGATGGGTTACACCTATCTTGAGGATTTTTAA

Upstream 100 bases:

>100_bases
CAGCCAACAAATCGTTTTCGAACGTTTTTTGTTGGGTTATACCTCGCTATTCCAATGAGGTATCTTCTGTCGATGGCCCT
ATAGTGTGAGGTCTCTAGAA

Downstream 100 bases:

>100_bases
TGAACGATCTATTTACCAAACCAGATTACTCGCTGTACTCCAACGCGATGACGTTTATGCGTCGCCCATTGGTGCAGAAC
CCAATTGATAACGATGCTGA

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MENSVNLERIRAEYNVKHWSQGFYGIDDNGEVYVSPSETDHQVPLSQIVKQLEQRNIGLPALVRFPQIVHQRVHNICNAF
NQAIDEYQYDNRYLLVYPIKVNQQKEVVDEILASQAQLEQKQLGLEAGSKPELLAVLALAQKASSVIVCNGYKDREYIRL
ALIGEKLGHKVFIVLEKLSELDLVLSEAKALGVKPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLTVIERLKAEDQ
LDVLELVHFHLGSQMANIRDVRNGVSEAARFYCELRDIGAQLKFLDVGGGLAVDYDGTRSQSSNSMNYGLLEYARNIVMT
VGDICKLYNQPQPVIISESGRSLTAHHAVLITNVIGTESYSPEDMAAPEADAPMLLNNMWKNFLELDAGNDDRALIEIYN
DTQSDIAEAHNQFATGMLNLQHRAWAEQMSLRINYELSSRMSTKNRYHRPILDELSERLADKFFVNFSLFQSLPDAWGID
QVFPVLPLSGLDNADERRAVVLDITCDSDGTIDQYVDGQGIETTLPVPAWNPDEPYLMGFFLVGAYQEILGDMHNLFGDT
HSVVVNVDESGQANIDYINEGDTVEDMMRYVHIDTDLIRQNYKDLVTAKVPAQEQQSVLEELEQGLMGYTYLEDF

Sequences:

>Translated_635_residues
MENSVNLERIRAEYNVKHWSQGFYGIDDNGEVYVSPSETDHQVPLSQIVKQLEQRNIGLPALVRFPQIVHQRVHNICNAF
NQAIDEYQYDNRYLLVYPIKVNQQKEVVDEILASQAQLEQKQLGLEAGSKPELLAVLALAQKASSVIVCNGYKDREYIRL
ALIGEKLGHKVFIVLEKLSELDLVLSEAKALGVKPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLTVIERLKAEDQ
LDVLELVHFHLGSQMANIRDVRNGVSEAARFYCELRDIGAQLKFLDVGGGLAVDYDGTRSQSSNSMNYGLLEYARNIVMT
VGDICKLYNQPQPVIISESGRSLTAHHAVLITNVIGTESYSPEDMAAPEADAPMLLNNMWKNFLELDAGNDDRALIEIYN
DTQSDIAEAHNQFATGMLNLQHRAWAEQMSLRINYELSSRMSTKNRYHRPILDELSERLADKFFVNFSLFQSLPDAWGID
QVFPVLPLSGLDNADERRAVVLDITCDSDGTIDQYVDGQGIETTLPVPAWNPDEPYLMGFFLVGAYQEILGDMHNLFGDT
HSVVVNVDESGQANIDYINEGDTVEDMMRYVHIDTDLIRQNYKDLVTAKVPAQEQQSVLEELEQGLMGYTYLEDF
>Mature_635_residues
MENSVNLERIRAEYNVKHWSQGFYGIDDNGEVYVSPSETDHQVPLSQIVKQLEQRNIGLPALVRFPQIVHQRVHNICNAF
NQAIDEYQYDNRYLLVYPIKVNQQKEVVDEILASQAQLEQKQLGLEAGSKPELLAVLALAQKASSVIVCNGYKDREYIRL
ALIGEKLGHKVFIVLEKLSELDLVLSEAKALGVKPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLTVIERLKAEDQ
LDVLELVHFHLGSQMANIRDVRNGVSEAARFYCELRDIGAQLKFLDVGGGLAVDYDGTRSQSSNSMNYGLLEYARNIVMT
VGDICKLYNQPQPVIISESGRSLTAHHAVLITNVIGTESYSPEDMAAPEADAPMLLNNMWKNFLELDAGNDDRALIEIYN
DTQSDIAEAHNQFATGMLNLQHRAWAEQMSLRINYELSSRMSTKNRYHRPILDELSERLADKFFVNFSLFQSLPDAWGID
QVFPVLPLSGLDNADERRAVVLDITCDSDGTIDQYVDGQGIETTLPVPAWNPDEPYLMGFFLVGAYQEILGDMHNLFGDT
HSVVVNVDESGQANIDYINEGDTVEDMMRYVHIDTDLIRQNYKDLVTAKVPAQEQQSVLEELEQGLMGYTYLEDF

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=624, Percent_Identity=54.4871794871795, Blast_Score=702, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71315; Mature: 71315

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSVNLERIRAEYNVKHWSQGFYGIDDNGEVYVSPSETDHQVPLSQIVKQLEQRNIGLP
CCCCCCHHHHHHHHCHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCH
ALVRFPQIVHQRVHNICNAFNQAIDEYQYDNRYLLVYPIKVNQQKEVVDEILASQAQLEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHH
KQLGLEAGSKPELLAVLALAQKASSVIVCNGYKDREYIRLALIGEKLGHKVFIVLEKLSE
HHHCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHEEEEEEHHHHCCEEEEHHHHHHH
LDLVLSEAKALGVKPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLTVIERLKAEDQ
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCH
LDVLELVHFHLGSQMANIRDVRNGVSEAARFYCELRDIGAQLKFLDVGGGLAVDYDGTRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCC
QSSNSMNYGLLEYARNIVMTVGDICKLYNQPQPVIISESGRSLTAHHAVLITNVIGTESY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEHHHHEEEEHHHCCCCC
SPEDMAAPEADAPMLLNNMWKNFLELDAGNDDRALIEIYNDTQSDIAEAHNQFATGMLNL
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
QHRAWAEQMSLRINYELSSRMSTKNRYHRPILDELSERLADKFFVNFSLFQSLPDAWGID
HHHHHHHHHHEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
QVFPVLPLSGLDNADERRAVVLDITCDSDGTIDQYVDGQGIETTLPVPAWNPDEPYLMGF
HHHHCCCCCCCCCCCCCEEEEEEEEECCCCCHHHCCCCCCCEEECCCCCCCCCCCHHHHH
FLVGAYQEILGDMHNLFGDTHSVVVNVDESGQANIDYINEGDTVEDMMRYVHIDTDLIRQ
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHCCHHHHHH
NYKDLVTAKVPAQEQQSVLEELEQGLMGYTYLEDF
HHHHHHEECCCCHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MENSVNLERIRAEYNVKHWSQGFYGIDDNGEVYVSPSETDHQVPLSQIVKQLEQRNIGLP
CCCCCCHHHHHHHHCHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCH
ALVRFPQIVHQRVHNICNAFNQAIDEYQYDNRYLLVYPIKVNQQKEVVDEILASQAQLEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHH
KQLGLEAGSKPELLAVLALAQKASSVIVCNGYKDREYIRLALIGEKLGHKVFIVLEKLSE
HHHCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHEEEEEEHHHHCCEEEEHHHHHHH
LDLVLSEAKALGVKPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLTVIERLKAEDQ
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCH
LDVLELVHFHLGSQMANIRDVRNGVSEAARFYCELRDIGAQLKFLDVGGGLAVDYDGTRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCC
QSSNSMNYGLLEYARNIVMTVGDICKLYNQPQPVIISESGRSLTAHHAVLITNVIGTESY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEHHHHEEEEHHHCCCCC
SPEDMAAPEADAPMLLNNMWKNFLELDAGNDDRALIEIYNDTQSDIAEAHNQFATGMLNL
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
QHRAWAEQMSLRINYELSSRMSTKNRYHRPILDELSERLADKFFVNFSLFQSLPDAWGID
HHHHHHHHHHEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
QVFPVLPLSGLDNADERRAVVLDITCDSDGTIDQYVDGQGIETTLPVPAWNPDEPYLMGF
HHHHCCCCCCCCCCCCCEEEEEEEEECCCCCHHHCCCCCCCEEECCCCCCCCCCCHHHHH
FLVGAYQEILGDMHNLFGDTHSVVVNVDESGQANIDYINEGDTVEDMMRYVHIDTDLIRQ
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHCCHHHHHH
NYKDLVTAKVPAQEQQSVLEELEQGLMGYTYLEDF
HHHHHHEECCCCHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA