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The map label for this gene is yhcS [C]

Identifier: 218709187

GI number: 218709187

Start: 1265820

End: 1266704

Strand: Direct

Name: yhcS [C]

Synonym: VS_1194

Alternate gene names: 218709187

Gene position: 1265820-1266704 (Clockwise)

Preceding gene: 218709185

Following gene: 218709188

Centisome position: 38.37

GC content: 47.23

Gene sequence:

>885_bases
ATGGATAGCTTTGAAGGTATTAATGAATTTGTTGCGGTAGCGGAGTGTCACGGCTTTTCTGCGGCCGCGAAACAACTGGG
TTGCAGTACTAGTCATGTCAGTCGCCAAGTGTCGAGATTAGAAGAGAGGGTAGGTGTGGCTTTACTCGCTCGATCCACTC
GTATGGTGAGTTTGACTGAGTCGGGGCATACCTATTATCAGCAATGCAAAGATCTGGTTATCGGGCTGCAACAGGCGAAT
GAACAAGTCACATCTCAACAAGCTCAGTTGAGCGGTACATTACGCGTGAGTGCTGCGGGTGCGTTTGCTGAAAATCATGT
TGCCGCGGCGATGATGGCATTTGCGAAAGACCACCCTGATCTGACTATCGAAATGAACTTCAATACCAATATGGTTAACT
TCATCGAAGATGGTATTGATTTCGCGATTCGTTATGGTCGACTTGATGATTCTGGTTTGGTGGCAAGGAAGCTGGTGGAT
CGGCCTATGGCAGCGGCCGCGAGTCAGAACTACATCGATCAATTCGGTTCTCCAACACAGCCTGAACAGTTGAAGTGGCA
CAGCTGTATTATTGCCAACAGTGATCAGTGGTTGTTTGAGAAAGATGGAAAACCGTTAAACGCGGTGCGCGTACATGGGC
GTTGGAAAAGCAATAACTCGAGTGCGGTACTTAAAGCTTGTGAAGAAGGGCTTGGCATTGTTTATCTTCCCAAAAGCAGC
TTCAATGGCGGTCTTGCCAATGGAAAGCTCGTTCCAGTGCTAGAAGAATATTGGGGAGCAGGTACAAGCAGTTGGATCGT
ATATCAAAACCGTCGCTTTCTTCCACAGAGAGCAAGGCTGGCTATCGACTTCTTAGTCTCTTATTTTTCCGATTGGAATG
AATAA

Upstream 100 bases:

>100_bases
TGAGTGATAATATGCCGAGTAGGCAAAACATTATTGCTATATAGCAATAGTGGATGTGAATTAGTCGGATGTGAACTCGT
TAGATGTAAACAGGTGAAGT

Downstream 100 bases:

>100_bases
CCGAATAGATAATGCTTACATAGCTATACAATATCCTTGTTGTTTTCTGATGTGCGTAATAAGAAGGTGCTATTTGTCTA
CTTTTGATGACTTACGCTTA

Product: transcriptional Regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDSFEGINEFVAVAECHGFSAAAKQLGCSTSHVSRQVSRLEERVGVALLARSTRMVSLTESGHTYYQQCKDLVIGLQQAN
EQVTSQQAQLSGTLRVSAAGAFAENHVAAAMMAFAKDHPDLTIEMNFNTNMVNFIEDGIDFAIRYGRLDDSGLVARKLVD
RPMAAAASQNYIDQFGSPTQPEQLKWHSCIIANSDQWLFEKDGKPLNAVRVHGRWKSNNSSAVLKACEEGLGIVYLPKSS
FNGGLANGKLVPVLEEYWGAGTSSWIVYQNRRFLPQRARLAIDFLVSYFSDWNE

Sequences:

>Translated_294_residues
MDSFEGINEFVAVAECHGFSAAAKQLGCSTSHVSRQVSRLEERVGVALLARSTRMVSLTESGHTYYQQCKDLVIGLQQAN
EQVTSQQAQLSGTLRVSAAGAFAENHVAAAMMAFAKDHPDLTIEMNFNTNMVNFIEDGIDFAIRYGRLDDSGLVARKLVD
RPMAAAASQNYIDQFGSPTQPEQLKWHSCIIANSDQWLFEKDGKPLNAVRVHGRWKSNNSSAVLKACEEGLGIVYLPKSS
FNGGLANGKLVPVLEEYWGAGTSSWIVYQNRRFLPQRARLAIDFLVSYFSDWNE
>Mature_294_residues
MDSFEGINEFVAVAECHGFSAAAKQLGCSTSHVSRQVSRLEERVGVALLARSTRMVSLTESGHTYYQQCKDLVIGLQQAN
EQVTSQQAQLSGTLRVSAAGAFAENHVAAAMMAFAKDHPDLTIEMNFNTNMVNFIEDGIDFAIRYGRLDDSGLVARKLVD
RPMAAAASQNYIDQFGSPTQPEQLKWHSCIIANSDQWLFEKDGKPLNAVRVHGRWKSNNSSAVLKACEEGLGIVYLPKSS
FNGGLANGKLVPVLEEYWGAGTSSWIVYQNRRFLPQRARLAIDFLVSYFSDWNE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=30.5084745762712, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI145693193, Length=308, Percent_Identity=30.5194805194805, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786401, Length=281, Percent_Identity=32.0284697508897, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=29.4314381270903, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=26.4084507042254, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787589, Length=270, Percent_Identity=28.1481481481481, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787128, Length=282, Percent_Identity=26.5957446808511, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790011, Length=285, Percent_Identity=24.9122807017544, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=25, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788706, Length=165, Percent_Identity=29.0909090909091, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786448, Length=245, Percent_Identity=24.8979591836735, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=140, Percent_Identity=26.4285714285714, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI157672245, Length=171, Percent_Identity=29.2397660818713, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787879, Length=167, Percent_Identity=27.5449101796407, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786508, Length=136, Percent_Identity=27.2058823529412, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32507; Mature: 32507

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSFEGINEFVAVAECHGFSAAAKQLGCSTSHVSRQVSRLEERVGVALLARSTRMVSLTE
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEEEC
SGHTYYQQCKDLVIGLQQANEQVTSQQAQLSGTLRVSAAGAFAENHVAAAMMAFAKDHPD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCCC
LTIEMNFNTNMVNFIEDGIDFAIRYGRLDDSGLVARKLVDRPMAAAASQNYIDQFGSPTQ
EEEEEECCCCHHHHHHHCHHHEEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
PEQLKWHSCIIANSDQWLFEKDGKPLNAVRVHGRWKSNNSSAVLKACEEGLGIVYLPKSS
CCCEEEEEEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCEEEECCCC
FNGGLANGKLVPVLEEYWGAGTSSWIVYQNRRFLPQRARLAIDFLVSYFSDWNE
CCCCCCCCEEEHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDSFEGINEFVAVAECHGFSAAAKQLGCSTSHVSRQVSRLEERVGVALLARSTRMVSLTE
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEEEC
SGHTYYQQCKDLVIGLQQANEQVTSQQAQLSGTLRVSAAGAFAENHVAAAMMAFAKDHPD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCCC
LTIEMNFNTNMVNFIEDGIDFAIRYGRLDDSGLVARKLVDRPMAAAASQNYIDQFGSPTQ
EEEEEECCCCHHHHHHHCHHHEEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
PEQLKWHSCIIANSDQWLFEKDGKPLNAVRVHGRWKSNNSSAVLKACEEGLGIVYLPKSS
CCCEEEEEEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCEEEECCCC
FNGGLANGKLVPVLEEYWGAGTSSWIVYQNRRFLPQRARLAIDFLVSYFSDWNE
CCCCCCCCEEEHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]