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The map label for this gene is csd [H]

Identifier: 218709185

GI number: 218709185

Start: 1263530

End: 1264765

Strand: Direct

Name: csd [H]

Synonym: VS_1192

Alternate gene names: 218709185

Gene position: 1263530-1264765 (Clockwise)

Preceding gene: 218709184

Following gene: 218709187

Centisome position: 38.3

GC content: 48.46

Gene sequence:

>1236_bases
ATGTCCTTCACTCTTAATGACGTGCGCCAACAGTTTAGCGCGTTAGGCCAATATCATAATGGCAAGCCAGTCACTTTCTT
TGATGGGCCGGGTGGCTCTCAGGTGCCTGAGAATGTTTTAGCATCAATGACCGAATACCTAGGGCATTTCAATTCAAACC
TAGGCGGCCACTATTTTTCTAGCCAAAAGACCACAAGTTTAATGCAGCAAGCGCGAGAAGCGGCGCAAGCACTGCTTAAT
GCGGAGTCTTCTGGCAACGTTGTGTTCGGAGCGAACATGACATCTCTGACCTTCCAATTGAGCCGAGCGATCAGTCGCGA
TTGGAAAAAGGGCGATGAAGTTATCGTCACGGCGTTAGACCATTACTCAAATGTATCGAGTTGGCAGCAAGCGGCAGATG
ACAAAGCCGCGATTGTTCGCCAAGTTCGCGTAGACGAGTCGGATTGCAGTTTGGATATGGCGCATTTTGAATCGCTGCTT
AACGAGAAAACCAAGCTTGTCGCGGTGACGTTTGCTTCAAACACGACAGGCTCGATTGTCGATATGGCGAAAGTGATCGA
GCTTGCACATCAGCATGGCGCGCAGGTTTATGTCGATGCCGTTCATTACGCGCCACACCATTTGGTCGATGTTCAGCAAT
TGAATTGTGATTTCTTAGCGTGTTCAGCGTATAAGTTCTTCGGCCCGCATGTGGGCATTGCTTATGTTGCGCCTCAATGG
TTACACACTTTAAAGCCTTACAAGGTTGAGCCTGCAACCAATATAGGCCCAGGTCGATTTGAGACAGGAACACAAAGCTT
TGAAGGCCTTGCCGGTGTGATTGCGGCGGTAGATTACTTGGCGCAGTTAGGCGATCCCGCCGATTCATTGCGTTCTCGTT
TAGAGCAAAGCTACGTGCTGTATAATAAGCATGAAAGCCAACTCAGCGAGTACTTCCTTAAACGCTTGGCCGACCTTGAA
GGGGCAAAGCTTTACGGGAAAACCGAGTTTGATTCGAACCTAAGAACCCCGACGTTTGCGATTACCTTTGATGCCCATTC
TCCAGAGTTCATCGCTAAGAAGTTGGGCGAGCATAATATCTGTGTTTGGAATGGTCACTTCTACGCATTAGGGCTGGTGA
AACAGTTGGGTATTGAAGAGCAGGGCGTGGTGCGTATTGGTTGTATGCATTATAACTCGATTGAAGAGATCGACTTGTTG
TTCAATGTGCTTGAAGGGATCTTGCGAAGCCACTAG

Upstream 100 bases:

>100_bases
GATAGTAAGCTTTGGCACAATGCACAACCGATTCGTACCATAGACCACGGCGAGATGGGCTACATGGATGTGTTTGTATT
AACGGCTAAGGATGCGCGCA

Downstream 100 bases:

>100_bases
CACTTAATCGCTATAGAATTAGAAAAGAGCATACTTCTCTCAATAATATTGAGTAGGAAGTATGCTCTTTTTATTTGATC
GAGCTTATATCTGTTTAACG

Product: putative cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSFTLNDVRQQFSALGQYHNGKPVTFFDGPGGSQVPENVLASMTEYLGHFNSNLGGHYFSSQKTTSLMQQAREAAQALLN
AESSGNVVFGANMTSLTFQLSRAISRDWKKGDEVIVTALDHYSNVSSWQQAADDKAAIVRQVRVDESDCSLDMAHFESLL
NEKTKLVAVTFASNTTGSIVDMAKVIELAHQHGAQVYVDAVHYAPHHLVDVQQLNCDFLACSAYKFFGPHVGIAYVAPQW
LHTLKPYKVEPATNIGPGRFETGTQSFEGLAGVIAAVDYLAQLGDPADSLRSRLEQSYVLYNKHESQLSEYFLKRLADLE
GAKLYGKTEFDSNLRTPTFAITFDAHSPEFIAKKLGEHNICVWNGHFYALGLVKQLGIEEQGVVRIGCMHYNSIEEIDLL
FNVLEGILRSH

Sequences:

>Translated_411_residues
MSFTLNDVRQQFSALGQYHNGKPVTFFDGPGGSQVPENVLASMTEYLGHFNSNLGGHYFSSQKTTSLMQQAREAAQALLN
AESSGNVVFGANMTSLTFQLSRAISRDWKKGDEVIVTALDHYSNVSSWQQAADDKAAIVRQVRVDESDCSLDMAHFESLL
NEKTKLVAVTFASNTTGSIVDMAKVIELAHQHGAQVYVDAVHYAPHHLVDVQQLNCDFLACSAYKFFGPHVGIAYVAPQW
LHTLKPYKVEPATNIGPGRFETGTQSFEGLAGVIAAVDYLAQLGDPADSLRSRLEQSYVLYNKHESQLSEYFLKRLADLE
GAKLYGKTEFDSNLRTPTFAITFDAHSPEFIAKKLGEHNICVWNGHFYALGLVKQLGIEEQGVVRIGCMHYNSIEEIDLL
FNVLEGILRSH
>Mature_410_residues
SFTLNDVRQQFSALGQYHNGKPVTFFDGPGGSQVPENVLASMTEYLGHFNSNLGGHYFSSQKTTSLMQQAREAAQALLNA
ESSGNVVFGANMTSLTFQLSRAISRDWKKGDEVIVTALDHYSNVSSWQQAADDKAAIVRQVRVDESDCSLDMAHFESLLN
EKTKLVAVTFASNTTGSIVDMAKVIELAHQHGAQVYVDAVHYAPHHLVDVQQLNCDFLACSAYKFFGPHVGIAYVAPQWL
HTLKPYKVEPATNIGPGRFETGTQSFEGLAGVIAAVDYLAQLGDPADSLRSRLEQSYVLYNKHESQLSEYFLKRLADLEG
AKLYGKTEFDSNLRTPTFAITFDAHSPEFIAKKLGEHNICVWNGHFYALGLVKQLGIEEQGVVRIGCMHYNSIEEIDLLF
NVLEGILRSH

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=432, Percent_Identity=29.8611111111111, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789175, Length=423, Percent_Identity=26.241134751773, Blast_Score=122, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45492; Mature: 45360

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTLNDVRQQFSALGQYHNGKPVTFFDGPGGSQVPENVLASMTEYLGHFNSNLGGHYFS
CCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
SQKTTSLMQQAREAAQALLNAESSGNVVFGANMTSLTFQLSRAISRDWKKGDEVIVTALD
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEHH
HYSNVSSWQQAADDKAAIVRQVRVDESDCSLDMAHFESLLNEKTKLVAVTFASNTTGSIV
HHCCHHHHHHHCCHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCEEEEEEEECCCCCHHH
DMAKVIELAHQHGAQVYVDAVHYAPHHLVDVQQLNCDFLACSAYKFFGPHVGIAYVAPQW
HHHHHHHHHHHCCCEEEEEEECCCCHHHEEHHHCCCCEEEECHHHHHCCCCCHHHHCHHH
LHTLKPYKVEPATNIGPGRFETGTQSFEGLAGVIAAVDYLAQLGDPADSLRSRLEQSYVL
HHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEE
YNKHESQLSEYFLKRLADLEGAKLYGKTEFDSNLRTPTFAITFDAHSPEFIAKKLGEHNI
ECCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCE
CVWNGHFYALGLVKQLGIEEQGVVRIGCMHYNSIEEIDLLFNVLEGILRSH
EEECCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFTLNDVRQQFSALGQYHNGKPVTFFDGPGGSQVPENVLASMTEYLGHFNSNLGGHYFS
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
SQKTTSLMQQAREAAQALLNAESSGNVVFGANMTSLTFQLSRAISRDWKKGDEVIVTALD
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEHH
HYSNVSSWQQAADDKAAIVRQVRVDESDCSLDMAHFESLLNEKTKLVAVTFASNTTGSIV
HHCCHHHHHHHCCHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCEEEEEEEECCCCCHHH
DMAKVIELAHQHGAQVYVDAVHYAPHHLVDVQQLNCDFLACSAYKFFGPHVGIAYVAPQW
HHHHHHHHHHHCCCEEEEEEECCCCHHHEEHHHCCCCEEEECHHHHHCCCCCHHHHCHHH
LHTLKPYKVEPATNIGPGRFETGTQSFEGLAGVIAAVDYLAQLGDPADSLRSRLEQSYVL
HHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEE
YNKHESQLSEYFLKRLADLEGAKLYGKTEFDSNLRTPTFAITFDAHSPEFIAKKLGEHNI
ECCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCE
CVWNGHFYALGLVKQLGIEEQGVVRIGCMHYNSIEEIDLLFNVLEGILRSH
EEECCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]