Click here to switch to the map view.

The map label for this gene is yrhP [H]

Identifier: 218709166

GI number: 218709166

Start: 1242074

End: 1242700

Strand: Direct

Name: yrhP [H]

Synonym: VS_1173

Alternate gene names: 218709166

Gene position: 1242074-1242700 (Clockwise)

Preceding gene: 218709160

Following gene: 218709167

Centisome position: 37.65

GC content: 42.11

Gene sequence:

>627_bases
ATGAGTTGGGACAGTATATCGCTGTTTATTGTTATCGTGTTTTTTATTGCCATTATTCCAGGCCCTAATGCTTTGCTGGT
ATTAAGCACAGCCTTAACTCAAAGGAAGCTGTTCGCATTTGTCAACGTGTTGGGTGTGTCATGTGGTTTCTTTTTTCACG
CCTTTATCTCGGCCAACGGCATAAGTTTGTTATTGTCGAACACCCCAATGGCCTTTGAAGGGCTTAAGTGGGCTGGGGTT
TTGTATCTTGTCTGGCTTGGGTATAACCATTTTCGTGCGGCACTGCGTGCTCAAGAGGGTGTACTTTATGCGGTAAGTGC
ATCGGGAAGTAAGCTATACAATCAATTTTTCAAAGGGCTCCTCACTAATCTACTGAATCCTAAAATCGTCCTGTTTTATC
TTTCTATATTCCCTCAATTTGTTTCAAAAGATGCGATTGTGACTGACAGTTTGATGCTTGGTGGGATTCAGGCGACAGTA
GTGTCGATGTGGTTCTTGATTGTGATTTTAATGGCGGATACGTTCAAGCGCTTGTTGGTTCAAAAGCGAACCTCACAAAT
GATGAACATTGTTTGTGGTGTTCTATTTGTGGGCTTTAGTATTCAACTAGCATTGTTTCAGCTCTGA

Upstream 100 bases:

>100_bases
TATGTTAGCCATACGCGATAATTAAACGTTTATCATATTGTAATGGCATTGAATGGACGTACAATGTCCGCCCTAAAAAT
GTTCATGAAATGAGTTCGAA

Downstream 100 bases:

>100_bases
GGTAGTGTTGCTAAGAATGGGGCATATACCATATTCTATTCAGTTCTCATTTTTTACTGAATCCTCAGGAATTTTAGAGT
CTCTTCATAAATGGCTAAAG

Product: putative homoserine/homoserine lactone efflux protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSWDSISLFIVIVFFIAIIPGPNALLVLSTALTQRKLFAFVNVLGVSCGFFFHAFISANGISLLLSNTPMAFEGLKWAGV
LYLVWLGYNHFRAALRAQEGVLYAVSASGSKLYNQFFKGLLTNLLNPKIVLFYLSIFPQFVSKDAIVTDSLMLGGIQATV
VSMWFLIVILMADTFKRLLVQKRTSQMMNIVCGVLFVGFSIQLALFQL

Sequences:

>Translated_208_residues
MSWDSISLFIVIVFFIAIIPGPNALLVLSTALTQRKLFAFVNVLGVSCGFFFHAFISANGISLLLSNTPMAFEGLKWAGV
LYLVWLGYNHFRAALRAQEGVLYAVSASGSKLYNQFFKGLLTNLLNPKIVLFYLSIFPQFVSKDAIVTDSLMLGGIQATV
VSMWFLIVILMADTFKRLLVQKRTSQMMNIVCGVLFVGFSIQLALFQL
>Mature_207_residues
SWDSISLFIVIVFFIAIIPGPNALLVLSTALTQRKLFAFVNVLGVSCGFFFHAFISANGISLLLSNTPMAFEGLKWAGVL
YLVWLGYNHFRAALRAQEGVLYAVSASGSKLYNQFFKGLLTNLLNPKIVLFYLSIFPQFVSKDAIVTDSLMLGGIQATVV
SMWFLIVILMADTFKRLLVQKRTSQMMNIVCGVLFVGFSIQLALFQL

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=197, Percent_Identity=29.4416243654822, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788099, Length=203, Percent_Identity=29.064039408867, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI48994979, Length=134, Percent_Identity=30.5970149253731, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23083; Mature: 22952

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWDSISLFIVIVFFIAIIPGPNALLVLSTALTQRKLFAFVNVLGVSCGFFFHAFISANG
CCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ISLLLSNTPMAFEGLKWAGVLYLVWLGYNHFRAALRAQEGVLYAVSASGSKLYNQFFKGL
EEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
LTNLLNPKIVLFYLSIFPQFVSKDAIVTDSLMLGGIQATVVSMWFLIVILMADTFKRLLV
HHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKRTSQMMNIVCGVLFVGFSIQLALFQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SWDSISLFIVIVFFIAIIPGPNALLVLSTALTQRKLFAFVNVLGVSCGFFFHAFISANG
CCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ISLLLSNTPMAFEGLKWAGVLYLVWLGYNHFRAALRAQEGVLYAVSASGSKLYNQFFKGL
EEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
LTNLLNPKIVLFYLSIFPQFVSKDAIVTDSLMLGGIQATVVSMWFLIVILMADTFKRLLV
HHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKRTSQMMNIVCGVLFVGFSIQLALFQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]