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The map label for this gene is gacS [H]

Identifier: 218709148

GI number: 218709148

Start: 1223554

End: 1227846

Strand: Direct

Name: gacS [H]

Synonym: VS_1155

Alternate gene names: 218709148

Gene position: 1223554-1227846 (Clockwise)

Preceding gene: 218709146

Following gene: 218709149

Centisome position: 37.09

GC content: 42.32

Gene sequence:

>4293_bases
ATGTTCCGCGCTTTTAATCTACTTTCTCTAATTATTCTGGCTTCTTCCGTATCTTTTTTCGGTAAGGCTAGTGGTTCGAT
TACCATCGGAGTTCAAACTTCAGGCTTTTCTCCGTATGTAGTTGTACAAGGTGGAGAGATTTCGGGACTGTTACCTGAAT
TAGCTAACTTTTATGCTAAAGACGAATTGAATGGCTTGGAGTTTGTTGGTTTTCATTCTCCGTCTGATCTAAACAACGTG
CTTAAAACGGAGCAAGTTGGTGCCATAATTACGGCTGAACAAAATATTTCTAGTAGCGGTGTTATTTACTCTAAACCTAT
TTTATCTAGCCGAATGGTTAGTCTAAGTAGCGAGCCTATTGAAACTCATTTATTGATGAAGGGCCGAAATCTCGCTTATT
TTGAAGGCTCAAGTAACGCGTCTTCTGTTAAGTCACTCCTTCCATTCTCTTCTTTTTCGTCATATTCATCTTATCAAAGC
GCTATCGCTGATGTTGCTCGCGAGAAAGCATTAGCCATTGTTGATGATGGTGTGCTACTACACAATAAGTTAATGAATAG
CCCCTATGAGTTATTCTTGTCGGTTAACTTGCATGATGATTTACCCCTAAATAATTACGTTATTGCCTTGCTGGATACTC
CTGAGAATAGGAAGGTGTTGGGTATTATCAATACCGCTATAAACCAAGATAACTCTAACAAACTTGTTAATATTCGTAAG
AAGTGGCTGAATGAAATACAGAGACGTTTGTTGTTGGTCGTTAGTAAAAATAAGCTGCTATTAACTGAAAAAGAGCAGCA
GTTCCTGCTTCTCAATCCGAACATATATGTATCATCTGAGACAGACTCGAAGCCTATTTCTTTCGAGAATAGTGAAGGTA
AGCCAGATGGTATTTCAATTGATATATTGAACGAGATATCCCGACTCACTGGGTTAAATTTTGTTTTTGAAAACGACCTC
GACCTTCAAGGTAACCAAGCTCACCCCGTATCTCTTCCTGTGATTCACACCAAGGCGACACCTTCTGCTGGTGGCGATGA
TCATCACCTCTACTCTAAACCGTTCATGGTTGAACCATGGGCACTGGTTGGTAAAAGTGATACGAGTAAATTGGCTGTGT
TCGGTGAATTAACGAAGAGCTCTATCATTGGAACCATAAATGACAGTGTCGGCATACAACTTGTTAAGCGTTATTGTGAG
GCTTGTCCAATCAAGACCTATAGCTCTGAGTTGCTTTTACTCGATGCTGTGGATAAAGGTGAGATTGATTCAGCGATGCT
TTCGCTTTATTTGGCATCACCTCTATTACAAGGGCAATATTCTGGGTATCTACGTGTAACGAGCTTACTGTCGAAGGACA
ATGATGTACCTGTAACATACAGTGTCGAAGCCGACCAAGAAGTGCTGAACAATATTATCAATAAAGCACTGTTCGCCATA
CCCCACCACAAGTATCAGCAGATTAAGAAACATTGGTTGGATGTATCTTATGAATCGGGCGTGGATACGGCAGATGTTGT
CTTGGGCGCTGCAATTTTAATCTCTGTCGCATCGGTGCTCATTATGCTTGTTATGGCATGGAGCTGGAAACTGAGACGTG
AAGTTGAAGACAGAAAGCGAACTGAATCCGCCCTCAAACATCAAGTGGAGTTCGAGCGTTCATTGTTGGACGCAATGCCG
TTTCCCATTGTTGTGCGTAACTTGGATAACCAGATAATCAGTTTGAACAGTGCCGCGCAGCAGCTTACCGGTTTTGAGTT
GATAGAAGGAGCCATCGTTAATAACTCCGATGAAGACACAATGATCCATCACGGGGTTGTTTTGCCTCGCTTAGAAAAAG
AAGTCGCTTCGCCGCAAGGCAGTAAACACTATGCGTATTGGAAGTGCCCGTATATCTCCAACGGGAATATCGAAGGCTCA
GTGACCATCCTTGATGATCTTACTGAGCTATATGAAGCAAAAAAAATAGCTAAAAGTGCCGATGATCGAGTACAGAAACT
TGCCAATAATTTGCATGGTGCGGTTATCCAGCATATTCAGCCTAAGCGAAGTCTGCATGATATTGAATTTGTATTTATCA
GTGATGGAGTCGAAGAGCTTTTGGGTCTCACTCCGGCTCAATTGCACCGCTCTCCGAATAGTTTTTTCGCCCCGCTGAAT
GCTCAAGACCGTAGAACCTTGATTAAGCGAGTACGTAGCGGAAATAAAGAGGGAAAACTAAGCCTCGATATCGGTGTGAA
TATTGATAATCAAAAACGATGGCTCAATTTGCAGAGCAAGATTTCTGACTTGGGTGAGTATTATGAATGGGACTCGGTTC
TAACTGATATCACTGAGCTTAAACAACAGCAAGAAGAGCTAACACAAGCAAGGCAAAGTGCTATTGCTGCCACTGAGGCA
AAGTCTCGATTTTTGGCCAACATGAGCCATGAAATTCGTACTCCATTGGGAGGGATTGTTAGCTTATTGGAATTGTCTGA
GCAATATGAGGTTGGTTATGAAGTTCAGAAGATCCATACAACGCTGAGTCAATCGGCGAATAACCTACTGCATATTGTTA
ACGATATACTCGATTTCTCGAAAATTGAAGCCGGTAAGCTGACCCTAGATTATCAGCCTGCAAGTCTAGATACATTGACT
CTTAGAGTGACTCAGTTGCAGGCGAGGCAAGCTCACGCCAAAGGGTTACAGTTCAAATTTTGGTTAGACCCTGAGTTGAA
TGATTTAGTCTTAATGGATGACATTCGTATTGGGCAAGTTCTGAATAATTTGTTGAGCAATGCCATTAAATTTACAGAAT
ATGGAACCGTAGGTTTAGCGGCAAAGTTACTCGACCTGGATGGTGAACAGCAACAAATTTGTTTCGAGGTGTTTGACAGT
GGCATCGGTATCAGTGAAGAACACATTCGAAACCTATTCCAACCTTTTGTTCAAGCCGATGAAGGAACCACGAGGAAATA
TGGTGGTTCAGGCCTTGGTTTGACTATCTCGAAGCAACTTATTGAACAAATGGGTGGGAGTCTTAACGTAACGAGTAAGA
TCAACATTGGTTCAACGTTCTCTATTACGCTGCCGCTTAAAACGCTCGCTGAAAATAACAGGGCGGACATGAATGGCAAG
GTGGCGCTACTTACCAAAACGTTCATGCAGCAATCTGAATTAGAGAACTATCTAACATCTTGGGGTATTAAGGTTATCTC
AAAGAATGTTCAGGTGACTAAAGAGCTCGCACACTGGGTCGATACCATTGAGCCTGATTTTGTGTTTATTCCTCATGAGC
TAGATCAGAGCATTGATACGTTCGCCGAAAGCGTGCAGTTTATTTGCGTCAGTGAACAAGGAATGCTTTCGCCTGCGCCA
TGCAAATTGGGCTGGAATCTGTCAGCAAACCCATTGTTGCCTTCGCAGTTGATGCACTGTTTGCACAACTGTCCTGCGTT
TGTGGAAGATGTTGTCCAAGATGATAATAATCTGAAATTGAGTACTGAGTCGCGCGAGTCTGCCAAACAGAATCAAAGAC
TTATCTTAATAGCGGAAGATCACCCAATCAATCAACAGATAATTCTTCAACAAATTGAGCAATTAGGTTTCCATGCCGAC
ATGGTAGATAACGGCAAGGAAGCACTTGTTGCCTTAGATAATGAAGATTATGGGCTGCTAATTACTGATTGCCACATGCC
AGAGATGGATGGGTATGAGTTAACAAGGCAGATCCGAGTAAAAGAGCAGAGCCAAAACCAACCTCGTCTTCCGATCATTG
CGTTAACCGCAAACGCTGTGCAAGGTGAAAATGATAAGTGCTTTGAGATTGGTATGGATGACTTCTTATCAAAACCAACC
AAATTAAGGGTGATTGGCGACACCATAATCAAACATCTTGATAAGGTGCAATCTGTTGTCGATAAGCCTTGTATTAGTTC
CTCGGAGCCTAAAAGTGAGCCGAGCTCTGCTCCGATTGATCTCGCCAACTTAACTGAATTGTTTGGTGACCAAGAGCTCG
TCATGCAGATCATCACTGACTTTATCAAGAGCCATCAAGCTGACATGCCTTTGCTTCAAGCTGCGTGTGAACAGCGAGAT
CTCGAAGCCATTAAACAGGTAGCTCATAAGATGAAGGGAGCTGCAAAAATGGTAGGCACAGAGGACATTGCCAATCAATT
GCAAACAATGGAATTGGTCTCCTTAAGTGACTTAGATGGTATTCAAGCACATTACGATAACCTCGAACAGCTGACGAACC
AATTGAAGACTTATTGTTCAGAATCAATCAAACCATTTAAGGAGCTACCATGA

Upstream 100 bases:

>100_bases
TTGCGTTGAACGAAAGTTACTTTTTGTTCAGTGCAAATTGGTGAGTTGATACGGTTAATACGATATAAGGTGCATTAATA
AATAAAACTCTAGGTTATTC

Downstream 100 bases:

>100_bases
ACCAGCATGTTGTAGTGATAGAAGATCACCCTTTTCAATTGAATGTAATGGGGATGGTTTTAAAAAGTTTGGGTATGGAA
AATGTCCAACCTTTTGAATG

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1430; Mature: 1430

Protein sequence:

>1430_residues
MFRAFNLLSLIILASSVSFFGKASGSITIGVQTSGFSPYVVVQGGEISGLLPELANFYAKDELNGLEFVGFHSPSDLNNV
LKTEQVGAIITAEQNISSSGVIYSKPILSSRMVSLSSEPIETHLLMKGRNLAYFEGSSNASSVKSLLPFSSFSSYSSYQS
AIADVAREKALAIVDDGVLLHNKLMNSPYELFLSVNLHDDLPLNNYVIALLDTPENRKVLGIINTAINQDNSNKLVNIRK
KWLNEIQRRLLLVVSKNKLLLTEKEQQFLLLNPNIYVSSETDSKPISFENSEGKPDGISIDILNEISRLTGLNFVFENDL
DLQGNQAHPVSLPVIHTKATPSAGGDDHHLYSKPFMVEPWALVGKSDTSKLAVFGELTKSSIIGTINDSVGIQLVKRYCE
ACPIKTYSSELLLLDAVDKGEIDSAMLSLYLASPLLQGQYSGYLRVTSLLSKDNDVPVTYSVEADQEVLNNIINKALFAI
PHHKYQQIKKHWLDVSYESGVDTADVVLGAAILISVASVLIMLVMAWSWKLRREVEDRKRTESALKHQVEFERSLLDAMP
FPIVVRNLDNQIISLNSAAQQLTGFELIEGAIVNNSDEDTMIHHGVVLPRLEKEVASPQGSKHYAYWKCPYISNGNIEGS
VTILDDLTELYEAKKIAKSADDRVQKLANNLHGAVIQHIQPKRSLHDIEFVFISDGVEELLGLTPAQLHRSPNSFFAPLN
AQDRRTLIKRVRSGNKEGKLSLDIGVNIDNQKRWLNLQSKISDLGEYYEWDSVLTDITELKQQQEELTQARQSAIAATEA
KSRFLANMSHEIRTPLGGIVSLLELSEQYEVGYEVQKIHTTLSQSANNLLHIVNDILDFSKIEAGKLTLDYQPASLDTLT
LRVTQLQARQAHAKGLQFKFWLDPELNDLVLMDDIRIGQVLNNLLSNAIKFTEYGTVGLAAKLLDLDGEQQQICFEVFDS
GIGISEEHIRNLFQPFVQADEGTTRKYGGSGLGLTISKQLIEQMGGSLNVTSKINIGSTFSITLPLKTLAENNRADMNGK
VALLTKTFMQQSELENYLTSWGIKVISKNVQVTKELAHWVDTIEPDFVFIPHELDQSIDTFAESVQFICVSEQGMLSPAP
CKLGWNLSANPLLPSQLMHCLHNCPAFVEDVVQDDNNLKLSTESRESAKQNQRLILIAEDHPINQQIILQQIEQLGFHAD
MVDNGKEALVALDNEDYGLLITDCHMPEMDGYELTRQIRVKEQSQNQPRLPIIALTANAVQGENDKCFEIGMDDFLSKPT
KLRVIGDTIIKHLDKVQSVVDKPCISSSEPKSEPSSAPIDLANLTELFGDQELVMQIITDFIKSHQADMPLLQAACEQRD
LEAIKQVAHKMKGAAKMVGTEDIANQLQTMELVSLSDLDGIQAHYDNLEQLTNQLKTYCSESIKPFKELP

Sequences:

>Translated_1430_residues
MFRAFNLLSLIILASSVSFFGKASGSITIGVQTSGFSPYVVVQGGEISGLLPELANFYAKDELNGLEFVGFHSPSDLNNV
LKTEQVGAIITAEQNISSSGVIYSKPILSSRMVSLSSEPIETHLLMKGRNLAYFEGSSNASSVKSLLPFSSFSSYSSYQS
AIADVAREKALAIVDDGVLLHNKLMNSPYELFLSVNLHDDLPLNNYVIALLDTPENRKVLGIINTAINQDNSNKLVNIRK
KWLNEIQRRLLLVVSKNKLLLTEKEQQFLLLNPNIYVSSETDSKPISFENSEGKPDGISIDILNEISRLTGLNFVFENDL
DLQGNQAHPVSLPVIHTKATPSAGGDDHHLYSKPFMVEPWALVGKSDTSKLAVFGELTKSSIIGTINDSVGIQLVKRYCE
ACPIKTYSSELLLLDAVDKGEIDSAMLSLYLASPLLQGQYSGYLRVTSLLSKDNDVPVTYSVEADQEVLNNIINKALFAI
PHHKYQQIKKHWLDVSYESGVDTADVVLGAAILISVASVLIMLVMAWSWKLRREVEDRKRTESALKHQVEFERSLLDAMP
FPIVVRNLDNQIISLNSAAQQLTGFELIEGAIVNNSDEDTMIHHGVVLPRLEKEVASPQGSKHYAYWKCPYISNGNIEGS
VTILDDLTELYEAKKIAKSADDRVQKLANNLHGAVIQHIQPKRSLHDIEFVFISDGVEELLGLTPAQLHRSPNSFFAPLN
AQDRRTLIKRVRSGNKEGKLSLDIGVNIDNQKRWLNLQSKISDLGEYYEWDSVLTDITELKQQQEELTQARQSAIAATEA
KSRFLANMSHEIRTPLGGIVSLLELSEQYEVGYEVQKIHTTLSQSANNLLHIVNDILDFSKIEAGKLTLDYQPASLDTLT
LRVTQLQARQAHAKGLQFKFWLDPELNDLVLMDDIRIGQVLNNLLSNAIKFTEYGTVGLAAKLLDLDGEQQQICFEVFDS
GIGISEEHIRNLFQPFVQADEGTTRKYGGSGLGLTISKQLIEQMGGSLNVTSKINIGSTFSITLPLKTLAENNRADMNGK
VALLTKTFMQQSELENYLTSWGIKVISKNVQVTKELAHWVDTIEPDFVFIPHELDQSIDTFAESVQFICVSEQGMLSPAP
CKLGWNLSANPLLPSQLMHCLHNCPAFVEDVVQDDNNLKLSTESRESAKQNQRLILIAEDHPINQQIILQQIEQLGFHAD
MVDNGKEALVALDNEDYGLLITDCHMPEMDGYELTRQIRVKEQSQNQPRLPIIALTANAVQGENDKCFEIGMDDFLSKPT
KLRVIGDTIIKHLDKVQSVVDKPCISSSEPKSEPSSAPIDLANLTELFGDQELVMQIITDFIKSHQADMPLLQAACEQRD
LEAIKQVAHKMKGAAKMVGTEDIANQLQTMELVSLSDLDGIQAHYDNLEQLTNQLKTYCSESIKPFKELP
>Mature_1430_residues
MFRAFNLLSLIILASSVSFFGKASGSITIGVQTSGFSPYVVVQGGEISGLLPELANFYAKDELNGLEFVGFHSPSDLNNV
LKTEQVGAIITAEQNISSSGVIYSKPILSSRMVSLSSEPIETHLLMKGRNLAYFEGSSNASSVKSLLPFSSFSSYSSYQS
AIADVAREKALAIVDDGVLLHNKLMNSPYELFLSVNLHDDLPLNNYVIALLDTPENRKVLGIINTAINQDNSNKLVNIRK
KWLNEIQRRLLLVVSKNKLLLTEKEQQFLLLNPNIYVSSETDSKPISFENSEGKPDGISIDILNEISRLTGLNFVFENDL
DLQGNQAHPVSLPVIHTKATPSAGGDDHHLYSKPFMVEPWALVGKSDTSKLAVFGELTKSSIIGTINDSVGIQLVKRYCE
ACPIKTYSSELLLLDAVDKGEIDSAMLSLYLASPLLQGQYSGYLRVTSLLSKDNDVPVTYSVEADQEVLNNIINKALFAI
PHHKYQQIKKHWLDVSYESGVDTADVVLGAAILISVASVLIMLVMAWSWKLRREVEDRKRTESALKHQVEFERSLLDAMP
FPIVVRNLDNQIISLNSAAQQLTGFELIEGAIVNNSDEDTMIHHGVVLPRLEKEVASPQGSKHYAYWKCPYISNGNIEGS
VTILDDLTELYEAKKIAKSADDRVQKLANNLHGAVIQHIQPKRSLHDIEFVFISDGVEELLGLTPAQLHRSPNSFFAPLN
AQDRRTLIKRVRSGNKEGKLSLDIGVNIDNQKRWLNLQSKISDLGEYYEWDSVLTDITELKQQQEELTQARQSAIAATEA
KSRFLANMSHEIRTPLGGIVSLLELSEQYEVGYEVQKIHTTLSQSANNLLHIVNDILDFSKIEAGKLTLDYQPASLDTLT
LRVTQLQARQAHAKGLQFKFWLDPELNDLVLMDDIRIGQVLNNLLSNAIKFTEYGTVGLAAKLLDLDGEQQQICFEVFDS
GIGISEEHIRNLFQPFVQADEGTTRKYGGSGLGLTISKQLIEQMGGSLNVTSKINIGSTFSITLPLKTLAENNRADMNGK
VALLTKTFMQQSELENYLTSWGIKVISKNVQVTKELAHWVDTIEPDFVFIPHELDQSIDTFAESVQFICVSEQGMLSPAP
CKLGWNLSANPLLPSQLMHCLHNCPAFVEDVVQDDNNLKLSTESRESAKQNQRLILIAEDHPINQQIILQQIEQLGFHAD
MVDNGKEALVALDNEDYGLLITDCHMPEMDGYELTRQIRVKEQSQNQPRLPIIALTANAVQGENDKCFEIGMDDFLSKPT
KLRVIGDTIIKHLDKVQSVVDKPCISSSEPKSEPSSAPIDLANLTELFGDQELVMQIITDFIKSHQADMPLLQAACEQRD
LEAIKQVAHKMKGAAKMVGTEDIANQLQTMELVSLSDLDGIQAHYDNLEQLTNQLKTYCSESIKPFKELP

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=534, Percent_Identity=31.8352059925094, Blast_Score=243, Evalue=7e-65,
Organism=Escherichia coli, GI1789149, Length=709, Percent_Identity=29.0550070521862, Blast_Score=240, Evalue=5e-64,
Organism=Escherichia coli, GI48994928, Length=257, Percent_Identity=37.3540856031128, Blast_Score=153, Evalue=8e-38,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=39.4422310756972, Blast_Score=150, Evalue=8e-37,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=37.9446640316205, Blast_Score=144, Evalue=6e-35,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=32.2033898305085, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=30.0448430493274, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=26.984126984127, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=28.1938325991189, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=28.4584980237154, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=27.3913043478261, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI1787894, Length=247, Percent_Identity=28.3400809716599, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=258, Percent_Identity=27.1317829457364, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=27.7310924369748, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=85, Percent_Identity=45.8823529411765, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 158879; Mature: 158879

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRAFNLLSLIILASSVSFFGKASGSITIGVQTSGFSPYVVVQGGEISGLLPELANFYAK
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHH
DELNGLEFVGFHSPSDLNNVLKTEQVGAIITAEQNISSSGVIYSKPILSSRMVSLSSEPI
CCCCCEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEECCHHHHHHHHCCCCCC
ETHLLMKGRNLAYFEGSSNASSVKSLLPFSSFSSYSSYQSAIADVAREKALAIVDDGVLL
CEEEEEECCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHH
HNKLMNSPYELFLSVNLHDDLPLNNYVIALLDTPENRKVLGIINTAINQDNSNKLVNIRK
HHHHHCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEHHHCCCCCCHHHHHHH
KWLNEIQRRLLLVVSKNKLLLTEKEQQFLLLNPNIYVSSETDSKPISFENSEGKPDGISI
HHHHHHHHHHEEEEECCEEEEEECCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCEEE
DILNEISRLTGLNFVFENDLDLQGNQAHPVSLPVIHTKATPSAGGDDHHLYSKPFMVEPW
HHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEECCH
ALVGKSDTSKLAVFGELTKSSIIGTINDSVGIQLVKRYCEACPIKTYSSELLLLDAVDKG
HEECCCCCCCEEEEEHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
EIDSAMLSLYLASPLLQGQYSGYLRVTSLLSKDNDVPVTYSVEADQEVLNNIINKALFAI
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHC
PHHKYQQIKKHWLDVSYESGVDTADVVLGAAILISVASVLIMLVMAWSWKLRREVEDRKR
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TESALKHQVEFERSLLDAMPFPIVVRNLDNQIISLNSAAQQLTGFELIEGAIVNNSDEDT
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEHHHHHHHHCCHHHHHCCEECCCCCCC
MIHHGVVLPRLEKEVASPQGSKHYAYWKCPYISNGNIEGSVTILDDLTELYEAKKIAKSA
EEECCEECHHHHHHHCCCCCCCCEEEEECCEECCCCCCEEEEHHHHHHHHHHHHHHHHHH
DDRVQKLANNLHGAVIQHIQPKRSLHDIEFVFISDGVEELLGLTPAQLHRSPNSFFAPLN
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHCCCHHHHHCCCCCEECCCC
AQDRRTLIKRVRSGNKEGKLSLDIGVNIDNQKRWLNLQSKISDLGEYYEWDSVLTDITEL
CHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQQQEELTQARQSAIAATEAKSRFLANMSHEIRTPLGGIVSLLELSEQYEVGYEVQKIHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
TLSQSANNLLHIVNDILDFSKIEAGKLTLDYQPASLDTLTLRVTQLQARQAHAKGLQFKF
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHCCCEEEE
WLDPELNDLVLMDDIRIGQVLNNLLSNAIKFTEYGTVGLAAKLLDLDGEQQQICFEVFDS
EECCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHC
GIGISEEHIRNLFQPFVQADEGTTRKYGGSGLGLTISKQLIEQMGGSLNVTSKINIGSTF
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEE
SITLPLKTLAENNRADMNGKVALLTKTFMQQSELENYLTSWGIKVISKNVQVTKELAHWV
EEEEEHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DTIEPDFVFIPHELDQSIDTFAESVQFICVSEQGMLSPAPCKLGWNLSANPLLPSQLMHC
HCCCCCEEEECHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LHNCPAFVEDVVQDDNNLKLSTESRESAKQNQRLILIAEDHPINQQIILQQIEQLGFHAD
HHCCHHHHHHHHCCCCCEEEECCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCC
MVDNGKEALVALDNEDYGLLITDCHMPEMDGYELTRQIRVKEQSQNQPRLPIIALTANAV
CCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCC
QGENDKCFEIGMDDFLSKPTKLRVIGDTIIKHLDKVQSVVDKPCISSSEPKSEPSSAPID
CCCCCCEEEECCHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LANLTELFGDQELVMQIITDFIKSHQADMPLLQAACEQRDLEAIKQVAHKMKGAAKMVGT
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCH
EDIANQLQTMELVSLSDLDGIQAHYDNLEQLTNQLKTYCSESIKPFKELP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MFRAFNLLSLIILASSVSFFGKASGSITIGVQTSGFSPYVVVQGGEISGLLPELANFYAK
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHH
DELNGLEFVGFHSPSDLNNVLKTEQVGAIITAEQNISSSGVIYSKPILSSRMVSLSSEPI
CCCCCEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEECCHHHHHHHHCCCCCC
ETHLLMKGRNLAYFEGSSNASSVKSLLPFSSFSSYSSYQSAIADVAREKALAIVDDGVLL
CEEEEEECCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHH
HNKLMNSPYELFLSVNLHDDLPLNNYVIALLDTPENRKVLGIINTAINQDNSNKLVNIRK
HHHHHCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEHHHCCCCCCHHHHHHH
KWLNEIQRRLLLVVSKNKLLLTEKEQQFLLLNPNIYVSSETDSKPISFENSEGKPDGISI
HHHHHHHHHHEEEEECCEEEEEECCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCEEE
DILNEISRLTGLNFVFENDLDLQGNQAHPVSLPVIHTKATPSAGGDDHHLYSKPFMVEPW
HHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEECCH
ALVGKSDTSKLAVFGELTKSSIIGTINDSVGIQLVKRYCEACPIKTYSSELLLLDAVDKG
HEECCCCCCCEEEEEHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
EIDSAMLSLYLASPLLQGQYSGYLRVTSLLSKDNDVPVTYSVEADQEVLNNIINKALFAI
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHC
PHHKYQQIKKHWLDVSYESGVDTADVVLGAAILISVASVLIMLVMAWSWKLRREVEDRKR
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TESALKHQVEFERSLLDAMPFPIVVRNLDNQIISLNSAAQQLTGFELIEGAIVNNSDEDT
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEHHHHHHHHCCHHHHHCCEECCCCCCC
MIHHGVVLPRLEKEVASPQGSKHYAYWKCPYISNGNIEGSVTILDDLTELYEAKKIAKSA
EEECCEECHHHHHHHCCCCCCCCEEEEECCEECCCCCCEEEEHHHHHHHHHHHHHHHHHH
DDRVQKLANNLHGAVIQHIQPKRSLHDIEFVFISDGVEELLGLTPAQLHRSPNSFFAPLN
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHCCCHHHHHCCCCCEECCCC
AQDRRTLIKRVRSGNKEGKLSLDIGVNIDNQKRWLNLQSKISDLGEYYEWDSVLTDITEL
CHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQQQEELTQARQSAIAATEAKSRFLANMSHEIRTPLGGIVSLLELSEQYEVGYEVQKIHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
TLSQSANNLLHIVNDILDFSKIEAGKLTLDYQPASLDTLTLRVTQLQARQAHAKGLQFKF
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHCCCEEEE
WLDPELNDLVLMDDIRIGQVLNNLLSNAIKFTEYGTVGLAAKLLDLDGEQQQICFEVFDS
EECCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHC
GIGISEEHIRNLFQPFVQADEGTTRKYGGSGLGLTISKQLIEQMGGSLNVTSKINIGSTF
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEE
SITLPLKTLAENNRADMNGKVALLTKTFMQQSELENYLTSWGIKVISKNVQVTKELAHWV
EEEEEHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DTIEPDFVFIPHELDQSIDTFAESVQFICVSEQGMLSPAPCKLGWNLSANPLLPSQLMHC
HCCCCCEEEECHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LHNCPAFVEDVVQDDNNLKLSTESRESAKQNQRLILIAEDHPINQQIILQQIEQLGFHAD
HHCCHHHHHHHHCCCCCEEEECCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCC
MVDNGKEALVALDNEDYGLLITDCHMPEMDGYELTRQIRVKEQSQNQPRLPIIALTANAV
CCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCC
QGENDKCFEIGMDDFLSKPTKLRVIGDTIIKHLDKVQSVVDKPCISSSEPKSEPSSAPID
CCCCCCEEEECCHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LANLTELFGDQELVMQIITDFIKSHQADMPLLQAACEQRDLEAIKQVAHKMKGAAKMVGT
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCH
EDIANQLQTMELVSLSDLDGIQAHYDNLEQLTNQLKTYCSESIKPFKELP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]