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The map label for this gene is engD [H]

Identifier: 218708749

GI number: 218708749

Start: 767121

End: 768272

Strand: Reverse

Name: engD [H]

Synonym: VS_0746

Alternate gene names: 218708749

Gene position: 768272-767121 (Counterclockwise)

Preceding gene: 218708750

Following gene: 218708748

Centisome position: 23.29

GC content: 44.53

Gene sequence:

>1152_bases
ATGGCCTACCAAAAGCACAAAATCGCTTACATACGTTCAAAGCAGAATAAGGTTTATATCATGGGTTTTAAATGTGGCAT
CGTTGGTCTACCAAACGTTGGTAAGTCAACTCTGTTTAACGCACTGACTAAAGCAGGCATCGAAGCAGCAAACTTTCCAT
TTTGTACGATCGAACCAAACACAGGTATCGTTCCGGTTCCAGATCTACGCTTAGATGCATTAGCAAAAATTGTTAATCCA
CAGAAGATCCTTCCAACGACAATGGAATTCGTAGATATCGCAGGCCTAGTTGCTGGCGCATCTAAAGGCGAAGGTCTAGG
TAACAAGTTCCTAGCTAACATCCGCGAAACTGATGCTATCGGTCACGTTGTACGCTGCTTTGAAAACGAAAACATCGTTC
ACGTTTCAGGCAAAGTATCACCTATCGAAGATATCGAAGTGATCAACCTTGAGCTTGCTCTTGCCGATCTAGATAGCTGT
GAACGTGCGATCTTCCGCAATGCTAAAAAAGCAAAAGGCGGCGATAAAGACGCTAAATTCGAAACTACGGTTCTTGAAAA
GCTACTACCTATCCTGACAGAAGGTGGTATGGCTCGTACTGTTGAACTTGCTAAAGAAGAAGTAGCGGCGATCGACTACC
TTAACTTCCTAACGCTTAAGCCAACAATGTACATCGCAAACGTTGCTGAAGATGGTTTTGAAAACAACCCTTACCTAGAC
GCAGTTCGTGAGTACGCAGAAAAAGAGAACAACGTTGTTGTTGCTGTTTGTGCTGCAATCGAATCTGAGCTTTCTGAACT
TGACGATGAAGATCGTGAGGAGTTCCTTGCAGACATGGGTATCGAAGAACCAGGCCTTAACCGAGTGATCCGCTCTGGTT
ACGAACTACTAACTCTTCAGACTTACTTCACTGCAGGTGTTAAAGAAGTTCGCGCTTGGACGATCCCTGTAGGTGCGACT
GCGCCACAAGCTGCAGGCAAGATCCACACCGACTTCGAAAAAGGATTCATCCGTGCAGAAGTAGTTGGTTACGAACATTT
CATCGAATTTGGCGGTGAAAGCGGAGCAAAAGATGCAGGTAAATGGCGTCTTGAAGGCAAAGAATACATCGTTAAAGACG
GTGATGTTGTTCACTTCCGTTTCAACGTTTAA

Upstream 100 bases:

>100_bases
GTTGCAGGTTATGTATTAGGCAAAGCTCCTGCGAAAGAGCAAGAGTGTATCGAGGCTGTCGTTGACGAATCGGTTCGTAG
CCTAGACATCTTATTGAAAG

Downstream 100 bases:

>100_bases
TTACCGATAAACATCTAATGAAAGGCCAGTGAATTCACTGGCCTTTTTCGTTTTCGCTCTTTCTAAAGAGCTTCTTATCC
AAAACTTAACTTCCTATATA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MAYQKHKIAYIRSKQNKVYIMGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGIVPVPDLRLDALAKIVNP
QKILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFENENIVHVSGKVSPIEDIEVINLELALADLDSC
ERAIFRNAKKAKGGDKDAKFETTVLEKLLPILTEGGMARTVELAKEEVAAIDYLNFLTLKPTMYIANVAEDGFENNPYLD
AVREYAEKENNVVVAVCAAIESELSELDDEDREEFLADMGIEEPGLNRVIRSGYELLTLQTYFTAGVKEVRAWTIPVGAT
APQAAGKIHTDFEKGFIRAEVVGYEHFIEFGGESGAKDAGKWRLEGKEYIVKDGDVVHFRFNV

Sequences:

>Translated_383_residues
MAYQKHKIAYIRSKQNKVYIMGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGIVPVPDLRLDALAKIVNP
QKILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFENENIVHVSGKVSPIEDIEVINLELALADLDSC
ERAIFRNAKKAKGGDKDAKFETTVLEKLLPILTEGGMARTVELAKEEVAAIDYLNFLTLKPTMYIANVAEDGFENNPYLD
AVREYAEKENNVVVAVCAAIESELSELDDEDREEFLADMGIEEPGLNRVIRSGYELLTLQTYFTAGVKEVRAWTIPVGAT
APQAAGKIHTDFEKGFIRAEVVGYEHFIEFGGESGAKDAGKWRLEGKEYIVKDGDVVHFRFNV
>Mature_382_residues
AYQKHKIAYIRSKQNKVYIMGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGIVPVPDLRLDALAKIVNPQ
KILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFENENIVHVSGKVSPIEDIEVINLELALADLDSCE
RAIFRNAKKAKGGDKDAKFETTVLEKLLPILTEGGMARTVELAKEEVAAIDYLNFLTLKPTMYIANVAEDGFENNPYLDA
VREYAEKENNVVVAVCAAIESELSELDDEDREEFLADMGIEEPGLNRVIRSGYELLTLQTYFTAGVKEVRAWTIPVGATA
PQAAGKIHTDFEKGFIRAEVVGYEHFIEFGGESGAKDAGKWRLEGKEYIVKDGDVVHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=45.1086956521739, Blast_Score=305, Evalue=6e-83,
Organism=Homo sapiens, GI58761502, Length=218, Percent_Identity=40.3669724770642, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=78.5123966942149, Blast_Score=593, Evalue=1e-171,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=31.496062992126, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=40.8219178082192, Blast_Score=288, Evalue=4e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=39.2953929539295, Blast_Score=252, Evalue=6e-68,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=35.1706036745407, Blast_Score=200, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6321649, Length=144, Percent_Identity=39.5833333333333, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=42.4731182795699, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=42.4731182795699, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=42.4731182795699, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24640879, Length=334, Percent_Identity=40.1197604790419, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24585318, Length=203, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 42068; Mature: 41936

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQKHKIAYIRSKQNKVYIMGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPN
CCCCCCEEEEEECCCCEEEEEEEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCC
TGIVPVPDLRLDALAKIVNPQKILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAI
CCEEECCCCHHHHHHHHCCCCHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GHVVRCFENENIVHVSGKVSPIEDIEVINLELALADLDSCERAIFRNAKKAKGGDKDAKF
HHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEEEHHHHHHHHHHHHCCHHCCCCCCCCHH
ETTVLEKLLPILTEGGMARTVELAKEEVAAIDYLNFLTLKPTMYIANVAEDGFENNPYLD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCEEEEEHHHCCCCCCCHHH
AVREYAEKENNVVVAVCAAIESELSELDDEDREEFLADMGIEEPGLNRVIRSGYELLTLQ
HHHHHHHCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEH
TYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAEVVGYEHFIEFGGESGAKDAG
HHHHHCHHHHEEEEEECCCCCCCCCCCEECHHHHCEEEEEEHHHHHHHHHCCCCCCCCCC
KWRLEGKEYIVKDGDVVHFRFNV
CEEECCCEEEEECCCEEEEEECC
>Mature Secondary Structure 
AYQKHKIAYIRSKQNKVYIMGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPN
CCCCCEEEEEECCCCEEEEEEEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCC
TGIVPVPDLRLDALAKIVNPQKILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAI
CCEEECCCCHHHHHHHHCCCCHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GHVVRCFENENIVHVSGKVSPIEDIEVINLELALADLDSCERAIFRNAKKAKGGDKDAKF
HHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEEEHHHHHHHHHHHHCCHHCCCCCCCCHH
ETTVLEKLLPILTEGGMARTVELAKEEVAAIDYLNFLTLKPTMYIANVAEDGFENNPYLD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCEEEEEHHHCCCCCCCHHH
AVREYAEKENNVVVAVCAAIESELSELDDEDREEFLADMGIEEPGLNRVIRSGYELLTLQ
HHHHHHHCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEH
TYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAEVVGYEHFIEFGGESGAKDAG
HHHHHCHHHHEEEEEECCCCCCCCCCCEECHHHHCEEEEEEHHHHHHHHHCCCCCCCCCC
KWRLEGKEYIVKDGDVVHFRFNV
CEEECCCEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA