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The map label for this gene is apaH [H]

Identifier: 218708406

GI number: 218708406

Start: 366785

End: 367588

Strand: Reverse

Name: apaH [H]

Synonym: VS_0368

Alternate gene names: 218708406

Gene position: 367588-366785 (Counterclockwise)

Preceding gene: 218708407

Following gene: 218708400

Centisome position: 11.14

GC content: 44.9

Gene sequence:

>804_bases
GTGTCGAATTATATTGTCGGAGACATTCAAGGATGCTTCGACGAGCTTAAGTTACTGCTTGAAACCATCAACTTTGATAA
ACAACAAGATACTTTATGGGTCGCCGGAGACTTAGTTGCTCGTGGCCCTAAATCCTTAGAGACGTTACGTTTTGTTCGTA
ACCTTGACAGTTCAGCGAAGGTGGTATTGGGTAACCATGATTTACATCTACTTGCTGTATCCTTAGGCCTCTTTTCAGCC
AAACCAAAAGACAAGACTCAACCAATTCTTGATGCTGAAGACCGTGACCAATTGCTGGAATGGTTAAGACAACAACCCTT
GATGCAAGAGCACCCAGAGTTTGTCATGACACATGCAGGCATCTCACCTCAATGGGACTTAGAACAAGCACGTACAGAGA
GTCGAGAGATAACGTCATTACTGAAATCGGACCGTTGGCAGTGGCTTATTGAGAACATGTACAGCAACACGCCAGATCTT
TGGAGCAACAAGTTACAAGACATCGAACGTTATCGCTATGCGATCAATAGCCTGACAAGAATGCGCTTCTGTTTTGAAGA
TGGCCGACTCGACATGGCATGTAAGCTACCACCGAATGAAATTACCGATGAACCACTAGTGCCATGGTTTGACCTTCCGC
AACGCATAAAGCTCGATAAAACCGTTGTTTTTGGACACTGGGCTGCGCTTGAAGGCTATAACGGAAAAGATGTAATTGGA
CTTGATACTGGGTGTGTGTGGGGGGGAGACTTGACGATACTTCGCTGGGAAGACAAACAGTTTTTCACTCAAAAAGCGCT
ATAG

Upstream 100 bases:

>100_bases
CATAAAGGCATTGATTTCATAACAGAAGTCGACCCATTTAGACTGGCTATCCCCAATATCCTTAACTAGTACGCATCTCT
ACCACTTACAGGAAAATACT

Downstream 100 bases:

>100_bases
AAACACGAGATACGAGATACGAGATACGAGATACGAGATACGAGATACGAGATACGAGATACGAGATACGAGATACGAGA
TACGAGATACGAGATACGAG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSNYIVGDIQGCFDELKLLLETINFDKQQDTLWVAGDLVARGPKSLETLRFVRNLDSSAKVVLGNHDLHLLAVSLGLFSA
KPKDKTQPILDAEDRDQLLEWLRQQPLMQEHPEFVMTHAGISPQWDLEQARTESREITSLLKSDRWQWLIENMYSNTPDL
WSNKLQDIERYRYAINSLTRMRFCFEDGRLDMACKLPPNEITDEPLVPWFDLPQRIKLDKTVVFGHWAALEGYNGKDVIG
LDTGCVWGGDLTILRWEDKQFFTQKAL

Sequences:

>Translated_267_residues
MSNYIVGDIQGCFDELKLLLETINFDKQQDTLWVAGDLVARGPKSLETLRFVRNLDSSAKVVLGNHDLHLLAVSLGLFSA
KPKDKTQPILDAEDRDQLLEWLRQQPLMQEHPEFVMTHAGISPQWDLEQARTESREITSLLKSDRWQWLIENMYSNTPDL
WSNKLQDIERYRYAINSLTRMRFCFEDGRLDMACKLPPNEITDEPLVPWFDLPQRIKLDKTVVFGHWAALEGYNGKDVIG
LDTGCVWGGDLTILRWEDKQFFTQKAL
>Mature_266_residues
SNYIVGDIQGCFDELKLLLETINFDKQQDTLWVAGDLVARGPKSLETLRFVRNLDSSAKVVLGNHDLHLLAVSLGLFSAK
PKDKTQPILDAEDRDQLLEWLRQQPLMQEHPEFVMTHAGISPQWDLEQARTESREITSLLKSDRWQWLIENMYSNTPDLW
SNKLQDIERYRYAINSLTRMRFCFEDGRLDMACKLPPNEITDEPLVPWFDLPQRIKLDKTVVFGHWAALEGYNGKDVIGL
DTGCVWGGDLTILRWEDKQFFTQKAL

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=269, Percent_Identity=50.1858736059479, Blast_Score=292, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 30926; Mature: 30794

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYIVGDIQGCFDELKLLLETINFDKQQDTLWVAGDLVARGPKSLETLRFVRNLDSSAK
CCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHCCCHHHHHHHHHHCCCCCCE
VVLGNHDLHLLAVSLGLFSAKPKDKTQPILDAEDRDQLLEWLRQQPLMQEHPEFVMTHAG
EEECCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCEEEEECC
ISPQWDLEQARTESREITSLLKSDRWQWLIENMYSNTPDLWSNKLQDIERYRYAINSLTR
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MRFCFEDGRLDMACKLPPNEITDEPLVPWFDLPQRIKLDKTVVFGHWAALEGYNGKDVIG
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEECCCEEEEEEHHEECCCCCCEEEE
LDTGCVWGGDLTILRWEDKQFFTQKAL
ECCCEEECCCEEEEEECCHHHHHHHCC
>Mature Secondary Structure 
SNYIVGDIQGCFDELKLLLETINFDKQQDTLWVAGDLVARGPKSLETLRFVRNLDSSAK
CCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHCCCHHHHHHHHHHCCCCCCE
VVLGNHDLHLLAVSLGLFSAKPKDKTQPILDAEDRDQLLEWLRQQPLMQEHPEFVMTHAG
EEECCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCEEEEECC
ISPQWDLEQARTESREITSLLKSDRWQWLIENMYSNTPDLWSNKLQDIERYRYAINSLTR
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MRFCFEDGRLDMACKLPPNEITDEPLVPWFDLPQRIKLDKTVVFGHWAALEGYNGKDVIG
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEECCCEEEEEEHHEECCCCCCEEEE
LDTGCVWGGDLTILRWEDKQFFTQKAL
ECCCEEECCCEEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA