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The map label for this gene is csgD [H]

Identifier: 218708362

GI number: 218708362

Start: 315532

End: 316179

Strand: Reverse

Name: csgD [H]

Synonym: VS_0322

Alternate gene names: 218708362

Gene position: 316179-315532 (Counterclockwise)

Preceding gene: 218708389

Following gene: 218708361

Centisome position: 9.58

GC content: 38.89

Gene sequence:

>648_bases
ATGAGAAAATCTCGATACGCTCGCACTTTACACTTTCTGTGCATCGACCCAAACGAAACCTATCTACACTTAAAAGAAAT
CGAAAAGCACTTATCCATTATTCTCTACAAAATGACGCCAGATGAATTGATGCTGGTTGATAGAAAGCAGAGCAATCGTA
TCCTTCTTGTTGATTACAAAGAGGTACCACAACTACTGGCTATTTGTCCTAACCTCCCCGTTATGTGGAAAAATCATGAA
ATAATCTTATTCAATGTGCCTCAGCAACTTCCTACCTCTGAGCTGCTAACCTACGGGGTATTAAAAGGACTCTTTTATAA
CACAGATCAAAAGGACAAGATTGCTCGTGGTCTTCAAGAAGTGATCGATGGTGATAATTGGTTACCAAGGAAGGTGACTA
ATCAGCTTCTGTTTTATTATCGTAATATGGTCAATACCAATACAACCCCAACCAATGTTGATTTAACTATTCGTGAAATC
CAAGTAATTCGCTGCCTTCAATCAGGATCATCAAATACCCAAATAGCTGATGACCTGTTCATTAGCGAATTCACGGTCAA
ATCCCACCTCTATCAAATATTCCGTAAATTAGCGGTGAAAAATAGAGTCCAAGCTATTGCATGGGCAAACCAAAACTTGC
TTGCATAA

Upstream 100 bases:

>100_bases
TTGAGAGTTGATATTCAACGCAAGTCACATAAAAGGTGCTAGAGAAGTAAAAATGTGCATGACAACGTGAAATCTAATTA
AATATAAACAGGACGTTTCA

Downstream 100 bases:

>100_bases
CCGCTCCGCTTCTAATCTGACAATAATTTTGAGGGAAGCTCGAGTAATCATAGGTATTGTTGCTGAATTTTCGACATAAC
ATATGCTAGAGTTGCCCTCA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MRKSRYARTLHFLCIDPNETYLHLKEIEKHLSIILYKMTPDELMLVDRKQSNRILLVDYKEVPQLLAICPNLPVMWKNHE
IILFNVPQQLPTSELLTYGVLKGLFYNTDQKDKIARGLQEVIDGDNWLPRKVTNQLLFYYRNMVNTNTTPTNVDLTIREI
QVIRCLQSGSSNTQIADDLFISEFTVKSHLYQIFRKLAVKNRVQAIAWANQNLLA

Sequences:

>Translated_215_residues
MRKSRYARTLHFLCIDPNETYLHLKEIEKHLSIILYKMTPDELMLVDRKQSNRILLVDYKEVPQLLAICPNLPVMWKNHE
IILFNVPQQLPTSELLTYGVLKGLFYNTDQKDKIARGLQEVIDGDNWLPRKVTNQLLFYYRNMVNTNTTPTNVDLTIREI
QVIRCLQSGSSNTQIADDLFISEFTVKSHLYQIFRKLAVKNRVQAIAWANQNLLA
>Mature_215_residues
MRKSRYARTLHFLCIDPNETYLHLKEIEKHLSIILYKMTPDELMLVDRKQSNRILLVDYKEVPQLLAICPNLPVMWKNHE
IILFNVPQQLPTSELLTYGVLKGLFYNTDQKDKIARGLQEVIDGDNWLPRKVTNQLLFYYRNMVNTNTTPTNVDLTIREI
QVIRCLQSGSSNTQIADDLFISEFTVKSHLYQIFRKLAVKNRVQAIAWANQNLLA

Specific function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA t

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787277, Length=170, Percent_Identity=36.4705882352941, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 25149; Mature: 25149

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSRYARTLHFLCIDPNETYLHLKEIEKHLSIILYKMTPDELMLVDRKQSNRILLVDYK
CCCCHHEEEEEEEEECCCCCEEEHHHHHHHHHEEEEEECCCCEEEEECCCCCCEEEEEHH
EVPQLLAICPNLPVMWKNHEIILFNVPQQLPTSELLTYGVLKGLFYNTDQKDKIARGLQE
HHHHHHHHCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VIDGDNWLPRKVTNQLLFYYRNMVNTNTTPTNVDLTIREIQVIRCLQSGSSNTQIADDLF
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEHHHHH
ISEFTVKSHLYQIFRKLAVKNRVQAIAWANQNLLA
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MRKSRYARTLHFLCIDPNETYLHLKEIEKHLSIILYKMTPDELMLVDRKQSNRILLVDYK
CCCCHHEEEEEEEEECCCCCEEEHHHHHHHHHEEEEEECCCCEEEEECCCCCCEEEEEHH
EVPQLLAICPNLPVMWKNHEIILFNVPQQLPTSELLTYGVLKGLFYNTDQKDKIARGLQE
HHHHHHHHCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VIDGDNWLPRKVTNQLLFYYRNMVNTNTTPTNVDLTIREIQVIRCLQSGSSNTQIADDLF
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEHHHHH
ISEFTVKSHLYQIFRKLAVKNRVQAIAWANQNLLA
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8817489; 8905232; 9278503 [H]