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The map label for this gene is yfbE

Identifier: 218700727

GI number: 218700727

Start: 2484924

End: 2486081

Strand: Direct

Name: yfbE

Synonym: ECIAI39_2400

Alternate gene names: 218700727

Gene position: 2484924-2486081 (Clockwise)

Preceding gene: 218700725

Following gene: 218700728

Centisome position: 48.42

GC content: 52.33

Gene sequence:

>1158_bases
ATGGCGGAAGGAAAAGCAATGTCAGAATTTTTGCCTTTTTCGCGACCAGCAATGGGCGTGGAGGAACTCGCTGCAGTTAA
AGAGGTTCTCGAATCCGGTTGGATCACAACCGGTCCGAAGAATCAGGCGCTTGAACAAGCCTTTTGCCAGTTGACGGGAA
ATCAGCATGCCATCGCGGTCAGTTCAGCCACCGCCGGAATGCATATCACGCTAATGGCGTTGGAAATTGGCAAGGGCGAT
GAAGTGATTACGCCTTCCCTGACCTGGGTTTCAACCCTCAATATGATCTCCTTGTTGGGTGCAACGCCGGTAATGGTGGA
TGTCGACCGCGATACGCTGATGGTCACGCCTGAAGCGATCGAGTCAGCCATTACGCCACGCACTAAAGCCATCATTCCGG
TGCATTATGCCGGTGCGCCAGCAGATATTGACGCCATTCGCGCCATTGGCGAACGTTACGGCATCGCAGTTATCGAAGAT
GCTGCCCATGCCGTCGGTACGTATTACAAAGGCCGACATATTGGCGCAAAAGGTACCGCTATTTTTTCGTTTCACGCCAT
CAAAAATATTACCTGTGCGGAAGGTGGCCTGATTGTTACTGATAATGAAAACCTTGCCCGCCAGCTACGGATGCTAAAAT
TTCACGGTCTGGGTGTCGATGCCTATGACAGACAAACCTGGGGCCGTGCACCGCAAGCTGAAGTCTTAACGCCGGGCTAT
AAGTATAATCTGACCGATATTAACGCCGCGATTGCCCTGACCCAGTTAGCCAAATTAGAGCACCTCAACACCCGTCGGCG
CGAAATTGCCCAGCAATATCAGCAAGCACTGGCAGCTCTCCCCTTTCAGCCATTAAGCCTTCCCGCCTGGCCGCACGTTC
ACGCCTGGCATCTGTTTATTATTCGTGTCGATGAACAACGTTGTGGTATCAGTCGCGATGCGTTGATGGAAGCGTTAAAA
GAAAGAGGCATTGGTACCGGGTTACATTTCCGCGCCGCTCACACACAAAAATATTATCGCGAGCGTTGTCCCACGCTGTC
GTTACCGAATACCGAATGGAATAGCGAACGCATCTGTTCGTTGCCGCTGTTCCCGGATATGACCACCGCCGATGCCGACC
GCGTCATCACAGCCCTTCAGCAACTCGCAGGACAATAA

Upstream 100 bases:

>100_bases
TTTCTTAAGGTTAAGTTAATATTCTATCCTTAAAATTTCGCTCCAAATGGCAAAATATACACAACACTCTTTATAGCAAA
TATAAGTGGACAGGTATTCA

Downstream 100 bases:

>100_bases
GCCATGTTTGAAATCCACCCTGTTAAGAAAGTCTCGGTGGTTATTCCCGTTTATAACGAGCAGGAAAGCTTACCGGAATT
AATCAGGCGCACCACAAAAG

Product: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase

Products: NA

Alternate protein names: UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase; UDP-Ara4O aminotransferase; UDP-4-amino-4-deoxy-L-arabinose aminotransferase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAEGKAMSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGD
EVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIED
AAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGY
KYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALK
ERGIGTGLHFRAAHTQKYYRERCPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ

Sequences:

>Translated_385_residues
MAEGKAMSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGD
EVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIED
AAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGY
KYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALK
ERGIGTGLHFRAAHTQKYYRERCPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ
>Mature_384_residues
AEGKAMSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDE
VITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDA
AHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYK
YNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKE
RGIGTGLHFRAAHTQKYYRERCPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ

Specific function: Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. ArnB subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=379, Percent_Identity=98.9445910290237, Blast_Score=776, Evalue=0.0,
Organism=Escherichia coli, GI2367285, Length=387, Percent_Identity=32.2997416020672, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022850
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: =2.6.1.87 [H]

Molecular weight: Translated: 42186; Mature: 42055

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGKAMSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAV
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
SSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAI
ECCCCCEEEEEEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCEEEECCCCEEEECHHHH
ESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTA
HHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCCE
IFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGY
EEEEHHHCCCEECCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCEECCCC
KYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFI
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
IRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERCPTLSLPNTEWNSERICS
EEECHHHCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
LPLFPDMTTADADRVITALQQLAGQ
CCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEGKAMSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAV
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
SSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAI
ECCCCCEEEEEEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCEEEECCCCEEEECHHHH
ESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTA
HHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCCE
IFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGY
EEEEHHHCCCEECCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCEECCCC
KYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFI
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
IRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERCPTLSLPNTEWNSERICS
EEECHHHCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
LPLFPDMTTADADRVITALQQLAGQ
CCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA