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The map label for this gene is narP

Identifier: 218700662

GI number: 218700662

Start: 2403455

End: 2404102

Strand: Direct

Name: narP

Synonym: ECIAI39_2331

Alternate gene names: 218700662

Gene position: 2403455-2404102 (Clockwise)

Preceding gene: 218700660

Following gene: 218700677

Centisome position: 46.83

GC content: 52.78

Gene sequence:

>648_bases
ATGCCTGAAGCAACGCCTTTTCAGGTGATGATTGTGGATGATCATCCACTTATGCGACGCGGTGTTCGTCAGTTACTGGA
GCTTGATCCTGGCTTTGAAGTGGTCGCCGAAGCGGGCGACGGCGCGAGCGCGATCGATCTGGCGAATAGACTGGATATCG
ACGTGATCTTACTGGATCTCAATATGAAAGGTATGAGTGGCCTGGATACCCTCAATGCCTTGCGCAGGGATGGCGTTACC
GCGCAAATTATTATCCTGACCGTATCCGATGCCTCCAGCGATGTCTTTGCGCTGATAGACGCAGGCGCAGACGGTTATCT
GTTGAAAGATAGCGACCCGGAAGTGTTGCTGGAAGCGATTCGTGCCGGAGCGAAAGGCAGCAAAGTCTTTAGCGAACGCG
TCAATCAGTACTTACGTGAACGTGAAATGTTTGGCGCGGAAGAAGATCCCTTCAGCGTGCTGACGGAGCGCGAGCTGGAT
GTTCTGCACGAGCTGGCACAGGGGCTGTCAAATAAACAGATTGCCTCGGTGTTGAATATTTCCGAGCAGACAGTAAAAGT
ACACATTCGCAATCTGCTGCGTAAACTCAATGTCCGCTCACGCGTGGCGGCCACCATTCTGTTCCTGCAACAACGCGGGG
CACAATAA

Upstream 100 bases:

>100_bases
ACATGTCCATACATAAAATGGGGTAACATTCACGCGCCTGGTAGCGTTACCAACGCTACGCTCAAACATAATGATTCTAA
TAAAACCTCAGGAGACTACT

Downstream 100 bases:

>100_bases
AAATAGCCCGATGGCATCACCATCGGGCCTCTTTTTATTTACTCTCCTGCGGCGACAAATGTTGCATCGCCTGCGCGATA
CTACGTTCAATCACCGCACG

Product: transcriptional regulator NarP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVT
AQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ

Sequences:

>Translated_215_residues
MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVT
AQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ
>Mature_214_residues
PEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTA
QIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELDV
LHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ

Specific function: This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=215, Percent_Identity=99.5348837209302, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1787473, Length=214, Percent_Identity=44.392523364486, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=32.0388349514563, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790102, Length=194, Percent_Identity=36.0824742268041, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=28.5, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1788712, Length=194, Percent_Identity=28.8659793814433, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788546, Length=200, Percent_Identity=31, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788191, Length=104, Percent_Identity=35.5769230769231, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23635; Mature: 23504

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASAIDLANRLDIDVILLDL
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHCCEEEEEEEE
NMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAI
CCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHH
RAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELDVLHELAQGLSNKQIASVLNI
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASAIDLANRLDIDVILLDL
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHCCEEEEEEEE
NMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAI
CCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHH
RAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELDVLHELAQGLSNKQIASVLNI
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501030; 9278503 [H]