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The map label for this gene is tonB

Identifier: 218699959

GI number: 218699959

Start: 1660466

End: 1661233

Strand: Direct

Name: tonB

Synonym: ECIAI39_1589

Alternate gene names: 218699959

Gene position: 1660466-1661233 (Clockwise)

Preceding gene: 218699956

Following gene: 218699963

Centisome position: 32.35

GC content: 53.12

Gene sequence:

>768_bases
TTGCATTTAAAATCGGGGCCTGGTTTTTCTACTGAAATGATTATGACTTCAATGACCCTTGATTTACCTCGCCGCTTCCC
ATGGCCGACGTTACTTTCGGTCTGCATTCATGGTGCTGTTGTGGCGGGTCTGCTCTATACCTCGGTACATCAGGTTATTG
AACTACCTGCGCCTGCGCAGCCCATTTCTGTCACGATGGTTGCGCCAGCGGATCTCGAACCGCCACAAGCCGTTCAACCC
CCACCGGAGCCGGTGGTAGAGCCAGAACCGGAACCTGAGCCGATCCCTGAACCGCCAAAAGAAGCTCCGGTGGTCATTGA
AAAGCCGAAGCCGAAACCTAAGCCAAAACCGAAGCCGGTGAAAAAGGTGGAGCAGCCAAAACGCGATGTCAAACCCGTAG
AGTCGCGTCCGGCATCACCGTTTGAAAATACGGCACCCGCGCGCCCGACATCAAGTACGGCAACGGCTGCAACCAGCAAG
CCGGTTACCAGTGTGGCTTCAGGACCACGCGCATTAAGCCGTAATCAGCCGCAGTATCCGGCACGAGCACAGGCATTGCG
CATTGAAGGGCAGGTTAAAGTTAAATTTGATGTCACGCCAGATGGTCGCGTGGATAACGTACAAATCCTCTCAGCCAAGC
CTGCAAACATGTTTGAGCGTGAGGTGAAAAATGCGATGCGCAGATGGCGTTATGAGCCGGGTAAGCCAGGCAGTGGGATT
GTGGTGAATATCCTGTTTAAAATTAACGGCACTACCGAAATTCAGTAA

Upstream 100 bases:

>100_bases
GATGTCTTTGTTAAGACCATGCATAAAGTAAGGTCAATTACGCCAAAAATGACATTTTCACTGATCCTGATCGTCTTGCC
TTATTGAATATGATTGCTAT

Downstream 100 bases:

>100_bases
GCATAAAGTCAAAAGCCTCCGACCGGAGGCTTTTGATTATTACTCAACAGGTAAGGCGCGAGGTTTTCCTTCGGGATCAA
CCGCGACATACTTAAATAAT

Product: transport protein TonB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MHLKSGPGFSTEMIMTSMTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQP
PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSK
PVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGI
VVNILFKINGTTEIQ

Sequences:

>Translated_255_residues
MHLKSGPGFSTEMIMTSMTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQP
PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSK
PVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGI
VVNILFKINGTTEIQ
>Mature_255_residues
MHLKSGPGFSTEMIMTSMTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQP
PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSK
PVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGI
VVNILFKINGTTEIQ

Specific function: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates such as cobalamin, and various iron compounds (such as iron dicitrate, enterochelin, aerobac

COG id: COG0810

COG function: function code M; Periplasmic protein TonB, links inner and outer membranes

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB family [H]

Homologues:

Organism=Escherichia coli, GI1787505, Length=239, Percent_Identity=98.744769874477, Blast_Score=353, Evalue=7e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003538
- InterPro:   IPR006260 [H]

Pfam domain/function: PF03544 TonB [H]

EC number: NA

Molecular weight: Translated: 27756; Mature: 27756

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLKSGPGFSTEMIMTSMTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPV
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCH
KKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYP
HHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHCCCCCCCC
ARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGI
CHHEEEEECCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCE
VVNILFKINGTTEIQ
EEEEEEEECCCCCCC
>Mature Secondary Structure
MHLKSGPGFSTEMIMTSMTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPV
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCH
KKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYP
HHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHCCCCCCCC
ARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGI
CHHEEEEECCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCE
VVNILFKINGTTEIQ
EEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6310567; 9097039; 9278503; 1885532; 8316087; 11328822 [H]