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The map label for this gene is blr

Identifier: 218699808

GI number: 218699808

Start: 1502568

End: 1502768

Strand: Reverse

Name: blr

Synonym: ECIAI39_1432

Alternate gene names: 218699808

Gene position: 1502768-1502568 (Counterclockwise)

Preceding gene: 218699810

Following gene: 218699807

Centisome position: 29.28

GC content: 41.29

Gene sequence:

>201_bases
TTGCTGGAGCTATTATTGCTAAGTAACATTTACCCCCTGAAGTTAATGGATCAATCAACAGAGATGTGGGCTGTAATGAA
TCGTCTTATTGAATTAACAGGTTGGATCGTTCTTGTCGTTTCAGTCATTCTTCTTGGCGTGGCGAGTCACATTGACAACT
ATCAGCCACCTGAACAGAGTACTACGGTTCAACACAAGTAA

Upstream 100 bases:

>100_bases
TAACCTGCCAGCAATAAGGGATGTTGTTTAACTTAAGTCAAAAAAATAGCGAATTTTCCAACGACAAAAGCTAAATATCG
CAAAAACCTCAGTAAAAATC

Downstream 100 bases:

>100_bases
GCTCTGCGCTTGTAGAGCGTCATGCTGCCCGTCCGGGTGCATGTTTTCACTTGTCGGATATTAAACCAGGAATTTATTAT
CTTGTTCGATGTTGTTGGTG

Product: beta-lactam resistance membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 66; Mature: 66

Protein sequence:

>66_residues
MLELLLLSNIYPLKLMDQSTEMWAVMNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSTTVQHK

Sequences:

>Translated_66_residues
MLELLLLSNIYPLKLMDQSTEMWAVMNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSTTVQHK
>Mature_66_residues
MLELLLLSNIYPLKLMDQSTEMWAVMNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSTTVQHK

Specific function: Has an effect on the susceptibiltiy to a number of antibiotics involved in peptidoglycan biosynthesis. Acts with beta lactams, D-cycloserine and bacitracin. Has no effect on the susceptibility to tetracycline, chloramphenicol, gentamicin, fosfomycin, vaco

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994886, Length=41, Percent_Identity=95.1219512195122, Blast_Score=83, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 7535; Mature: 7535

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELLLLSNIYPLKLMDQSTEMWAVMNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQS
CCHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TTVQHK
CCCCCC
>Mature Secondary Structure
MLELLLLSNIYPLKLMDQSTEMWAVMNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQS
CCHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TTVQHK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10931331; 9278503 [H]