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The map label for this gene is baeS

Identifier: 218695700

GI number: 218695700

Start: 2392906

End: 2394309

Strand: Direct

Name: baeS

Synonym: EC55989_2334

Alternate gene names: 218695700

Gene position: 2392906-2394309 (Clockwise)

Preceding gene: 218695699

Following gene: 218695701

Centisome position: 46.42

GC content: 54.06

Gene sequence:

>1404_bases
ATGAAGTTCTGGCGACCCGGTATTACCGGCAAACTGTTTCTGGCGATTTTCGCCACCTGCATTGTCTTGCTGATCAGTAT
GCACTGGGCGGTGCGTATCAGTTTTGAGCGTGGCTTTATTGATTACATCAAGCATGGTAATGAACAGCGATTACAACTGT
TAAGTGATGCGCTTGGCGAGCAGTATGCGCAGCATGGCAACTGGCGCTTCCTGCGCAACAATGATCGCTTTGTCTTTCAG
ATCCTGCGTTCATTTGAACACGATAATTCGGAAGATAAACCCGGCCCGGGTATGCCACCGCACGGCTGGCGTACCCAGTT
CTGGGTGGTTGATCAAAACAACAAAGTGCTGGTTGGTCCGCGAGCGCCGATTCCACCTGACGGTACACGGCGACCCATTC
TGGTCAACGGTGCGGAAGTTGGCGCGGTGATCGCCTCCCCCGTTGAGCGGTTAACGCGCAATACTGATATCAATTTCGAT
AAACAACAGCGGCAAACCAGCTGGTTGATTGTCGCTCTGGCAACGTTACTCGCGGCGCTCGCCACCTTTCTGCTGGCGCG
TGGTCTGTTGGCCCCGGTCAAACGGCTGGTGGACGGCACGCACAAACTGGCGGCGGGCGATTTCACTACCCGCGTAACGC
CCACCAGTGAAGATGAACTGGGCAAACTGGCGCAAGACTTCAACCAGCTCGCCAGCACGCTGGAGAAAAACCAGCAAATG
CGGCGCGATTTTATGGCTGATATTTCTCACGAACTGCGTACGCCATTAGCGGTGCTGCGCGGTGAACTGGAAGCCATTCA
GGATGGCGTGCGTAAATTCACGCCGGAGACGGTGGCGTCTTTACAGGCGGAGGTCGGTACACTGACCAAACTGGTTGACG
ATCTTCATCAGTTGTCGATGTCTGATGAAGGCGCTCTCGCCTATCAAAAAGCACCGGTAGATTTGATCCCACTGCTGGAA
GTGGCGGGCGGCGCATTTCGCGAACGATTTGCCAGCCGTGGCCTGAAACTGCAATTTTCCCTGCCAGACAGTATTACCGT
ATTTGGCGATCGCGACCGTTTAATGCAGTTATTCAATAACTTACTTGAAAACAGCCTGCGCTACACTGACAGCGGCGGCA
GCCTGAAAATCTCTGCCGAGCAGCACGACAAAACGGTGCGCCTGACCTTTGCCGACAGTGCGCCAGGTGTCAGTGACGAT
CAGCTACAAAAATTGTTTGAACGTTTTTATCGCACCGAAGGTTCCCGCAACCGCGCCAGCGGCGGTTCCGGGCTGGGGCT
GGCGATTTGCCTGAACATTGTTGAAGCACATAATGGCCGCATTATTGCTGCCCATTCGCCTTTTGGCGGGGTAAGCATTA
CAGTAGAGTTACCGCTGGAACGGGATTTACAGAGAGAAGTATGA

Upstream 100 bases:

>100_bases
GCATGGCGTTGATCATCGCCCTTCCGGCGTTCATCTTTGCCAGAGTGCCGAACGATACGCATCAAAATGTAGCTATTTCG
CGGCGAAAAAGGAGCGCGCA

Downstream 100 bases:

>100_bases
CCGAGTTACCAATCGACGAAAACACACCGCGTATTTTGATCGTGGAAGATGAACCGAAGCTGGGACAGTTGCTCATTGAT
TATCTGCGTGCTGCGAGCTA

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSFEHDNSEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV

Sequences:

>Translated_467_residues
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSFEHDNSEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
>Mature_467_residues
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSFEHDNSEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=467, Percent_Identity=99.3576017130621, Blast_Score=946, Evalue=0.0,
Organism=Escherichia coli, GI1786783, Length=295, Percent_Identity=28.8135593220339, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=28.3088235294118, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=29.7101449275362, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=27.6679841897233, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787374, Length=297, Percent_Identity=25.5892255892256, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=28.6885245901639, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788279, Length=292, Percent_Identity=26.7123287671233, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=30, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87081816, Length=254, Percent_Identity=28.740157480315, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=27.7591973244147, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787894, Length=307, Percent_Identity=23.4527687296417, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87082128, Length=292, Percent_Identity=24.3150684931507, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=28, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789808, Length=289, Percent_Identity=26.643598615917, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=25.7575757575758, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=320, Percent_Identity=22.8125, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=299, Percent_Identity=28.7625418060201, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=25, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52045; Mature: 52045

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQLLSDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSFEHDNSEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFDKQQRQTSWLIVALATLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKAPVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC
>Mature Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQLLSDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSFEHDNSEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFDKQQRQTSWLIVALATLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKAPVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]